Researcher

My Expertise

  • Design of biomaterials and nanomaterials to direct cell responses
  • Biophysical analyses of protein and cell interactions with biomaterials and nanomaterials
  • Extracellular matrix molecule biochemistry
  • In vitro and in vivo models of angiogenesis

 

Keywords

Fields of Research (FoR)

Biomedical engineering, Regenerative medicine (incl. stem cells), Nanomaterials, Biomaterials, Cellular interactions (incl. adhesion, matrix, cell wall)

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Biography

Megan Lord is Associate Professor of Biomedical Engineering, UNSW Sydney. She attained a Doctor of Philosophy in Engineering, Master of Biomedical Engineering and First class Honours degree in Chemical Engineering from UNSW. She leads a research program in biomaterials design to direct cell responses for applications in tissue repair and drug delivery. She is recognised as a leader in the field of biomaterials and specifically the engineering...view more

Megan Lord is Associate Professor of Biomedical Engineering, UNSW Sydney. She attained a Doctor of Philosophy in Engineering, Master of Biomedical Engineering and First class Honours degree in Chemical Engineering from UNSW. She leads a research program in biomaterials design to direct cell responses for applications in tissue repair and drug delivery. She is recognised as a leader in the field of biomaterials and specifically the engineering of biomaterial-cell interactions for applications in tissue repair, drug delivery and cell technologies.

Megan’s research has been published in more than 90 peer reviewed publications and she has trained 16 PhD/MPhil candidates as primary supervisor. Her research has been supported by national grants including a prestigious ARC Future Fellowship and has been recognised by an NSW Young Tall Poppy Award.

Megan serves on the Standards Australia Committee HE-030 Biological and Clinical Evaluation of Medical Devices that reviews and ratifies ISO 10993 and TC 194. She is the Past-President, Matrix Biology Society of Australia and New Zealand, Council Member, International Society for Matrix Biology and Associate Editor, IEEE Engineering in Medicine and Biology Society Conference Proceedings. She is the founding Academic Director of both the Molecular Surface Interaction Laboratory, Mark Wainwright Analytical Centre and the Australian Graduate School of Engineering (AGSE) Industry PhD Program.


My Grants

 

Australian Research Council Future Fellowship (2022-2026) Engineering nanomaterial interactions with the cell surface.
Australian Research Council Linkage Project with Synedgen Inc (2020-2023) Understanding glycopolymer interactions with the extracellular matrix.
Diabetes Australia General Grant (2019) Bioengineered growth factor binding scaffolds.
Australian Research Council Linkage Infrastructure, Equipment and Facilities (2019) Advanced mechanical property testing suite.
Australian Research Council Discovery Project (2015-2019) Novel biomimetic vascular biomaterials using extracellular matrix molecules.
Australian Research Council Linkage Project with the Australian Red Cross Blood Service (2014-2019) Biomimetic blood bag materials for prolonged platelet storage.
Australian Research Council Linkage Project with Cochlear Ltd (2014-2018) Biological determinants of the safety and stability of neuroprosthetic stimulation electrodes.
National Heart Foundation (2011-2012) The roles of perlecan heparan sulphate in modulating vascular intimal hyperplasia.
Australian Research Council Linkage Project with Synedgen Inc (including Australian Postdoctoral Fellowship) (2010-2014) Targeted growth factor delivery using natural polysaccharide materials for bone regeneration.
Australian Research Council Discovery Project (2010-2013) Advanced nanoparticles as biocompatible antioxidant agents with targeting functionality.
Australian Research Council Linkage Project with HemCon Medical Technologies (2007-2010) Blood component interactions with polysaccharide biomaterials for vascular applications.

In addition, Associate Professor Lord has been awarded grant funding from UNSW through the Research Infrastructure Scheme, Career Advancement Fund, Faculty of Engineering Carers Award, Faculty of Engineering Early Career Researcher fund and School project support.


My Qualifications

Bachelor of Engineering (Chemical Engineering) (Hons I), University of New South Wales
Master of Biomedical Engineering, University of New South Wales
Doctor of Philosophy, University of New South Wales


My Awards

Selected:
Barry Preston Award from the Matrix Biology Society of Australia and New Zealand recognised leadership in the field of matrix biology distinguished by a sustained record of achievement, commitment to mentoring junior researchers and exceptional communication skills (2022)
UNSW Faculty of Engineering Excellence in Leadership award (2020)
Matrix Biology Society of Australia and New Zealand Paper of the Month and Year Award (2020) - Mid-career category
NSW Young Tall Poppy Science Award in recognition of the achievements of Australia’s outstanding young scientific researchers and communicators. (2014)
UNSW Emeritus Professor Maria Skyllas-Kazacos Young Professional Award for Outstanding Achievement Award for female alumni from UNSW Engineering in recognition of a significant achievement in their field. (2013)
New Investigator Award from the Matrix Biology Society of Australia and New Zealand recognised the research achievements of early career researchers in the field of matrix biology with less than 10 years post-doctoral experience. (2008)
 


My Research Activities

Designing nanomaterials for drug delivery, diagnostics and cell technologies. I develop models to study biomaterial interactions with cells replicating the cell surface in vivo. This research is enabling the design of biomaterials for controlled interactions with cells including efficient intracellular delivery, overcoming the current and critical challenges to widespread use in therapies, drug delivery, diagnostics and cell technologies.

Engineering biomaterials for tissue regeneration. I develop biomaterial scaffolds that encourage the formation of new blood vessels overcoming challenges in current approaches associated with high manufacturing cost and off-target effects.


My Research Supervision


Supervision keywords


Areas of supervision

Megan welcomes expressions of interest to join her team at the Honours, Masters and Doctorate levels.

PhD/Masters positions available. Megan is seeking expressions of interest from talented candidates to design nanomaterials for drug delivery through understanding their interactions with cells. These findings have implications for the discovery of effective drug delivery approaches for applications in cardiovascular disease, diabetes and cancer. This project is suited to candidates interested in developing their skills in biomaterials, biochemistry and biophysics. Please contact Megan for more information.

 


Currently supervising

Post-doctoral Research Fellows
Dr Lu Fu
Dr Ha Na Kim

Current PhD/MPhil Candidates
Claire BridgesExploring glycopolymer interactions with blood vessels in diabetic conditions
Amy Jiang, In vitro and in vivo performance of perlecan coated biomaterials for vascular applications
Habib JoukhdarSilk fibroin as a biomaterial for cardiac patches

PhD/MPhil alumni (selected)
Dr Keerthana Chandrasekar, Klick
Dr Ted Chang, Sydney Children's Hospitals Network
Dr Lu Fu, University of New South Wales
Dr Ha Na Kim, University of New South Wales
Dr Kieran Lau, Nanyang Technical University
Bitong Li, University of New South Wales
Dr Deepika Nandakumar, ALS
Dr Chun-yi Ng, Grand Pacific CRO
Dr Fengying Tang, University of Washington
Dr James Vassie, University of New South Wales
Dr Joel Yong, University of New South Wales

 

 


My Engagement

University leadership
Academic Director, Australian Graduate School of Engineering Industry PhD Program, Faculty of Engineering
Academic Director, Molecular Surface Interaction Laboratory, Mark Wainwright Analytical Centre

Professional leadership
Past President, Matrix Biology Society of Australia and New Zealand
Member, Standards Australia Committee HE-030 Biological and Clinical Evaluation of Medical Devices who represent Australia on the ISO technical committee 194 working groups responsible for the ISO10993 standard
Council Member, International Society for Matrix Biology
Member, Australasian Society for Biomaterials and Tissue Engineering

Editorial positions
Editorial Board, Cellular Signalling
Associate Editor, IEEE Engineering in Medicine and Biology Society Conference Proceedings


My Teaching

Cellular and Tissue Engineering (BIOM9333)
Research Thesis (BIOM4951/4952/4953)
Research Thesis Biomedical Engineering (BIOM9020/9021)
Engineering Postgraduate Research Essentials (GSOE9400)
Medical Biotechnology (BABS3061)

 

 

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Location

Samuels Building F25
Level 5, Room 505
UNSW
Sydney NSW 2052
AUSTRALIA


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Contact

+61 2 9385 3910

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