By Associate Professor Tanya Lynn Applegate

Journal articles

Grebely J; Feld JJ; Applegate T; Matthews GV; Hellard M; Sherker A; Petoumenos K; Zang G; Shaw I; Yeung B; George J; Teutsch S; Kaldor JM; Cherepanov V; Bruneau J; Shoukry NH; Lloyd AR; Dore GJ, 2013, 'Plasma interferon-gamma-inducible protein-10 (IP-10) levels during acute hepatitis C virus infection', Hepatology, 57, pp. 2124 - 2134, http://dx.doi.org/10.1002/hep.26263

Grebely J; Hellard M; Applegate TL; Petoumenos K; Yeung B; Feld J; Rawlinson WD; Lloyd AR; George J; Kaldor JM; Dore GJ; Matthews G; Dolan K, 2012, 'Virological responses during treatment for recent hepatitis C virus: Potential benefit for ribavirin use in HCV/HIV co-infection', AIDS, 26, pp. 1653 - 1661, http://dx.doi.org/10.1097/QAD.0b013e3283553719

Mcintyre GJ; Groneman JL; Yu YH; Tran A; Applegate TL, 2011, 'Multiple shRNA combinations for near-complete coverage of all HIV-1 strains', AIDS Research and Therapy, 8, pp. 1, http://www.aidsrestherapy.com/content/8/1/1

Applegate TL; Birkett DJ; Mcintyre GJ; Jaramillo AB; Symonds G; Murray JM, 2010, 'In silico modeling indicates the development of HIV-1 resistance to multiple shRNA gene therapy differs to standard antiretroviral therapy', Retrovirology, 7:83, pp. 1 - 14, http://www.retrovirology.com/content/7/1/83

Grebely J; Petoumenos K; Hellard M; Matthews G; Suppiah V; Applegate TL; Yeung B; Marks P; Rawlinson WD; Lloyd AROLA; Booth D; Kaldor JM; George J; Dore GJ; Amin J; Cameron B; Acraman B; Dolan K; Bloch M; Van Beek I; Li H; Madden A, 2010, 'Potential Role for Interleukin-28B Genotype in Treatment Decision-Making in Recent Hepatitis C Virus Infection', Hepatology, 52, pp. 1216 - 1224, http://dx.doi.org/10.1002/hep.23850

Mcintyre GJ; Groneman JL; Yu YH; Jaramillo A; Shen S; Applegate TL, 2009, '96 shRNAs designed for maximal coverage of HIV-1 variants', Retrovirology, 6, http://dx.doi.org/10.1186/1742-4690-6-55

Mcintyre GJ; Yu Y; Tran A; Jaramillo AB; Arndt AJ; Millington ML; Boyd MP; Elliott FA; Shen SW; Murray JM; Applegate TL, 2009, 'Cassette deletion in multiple shRNA lentiviral vectors for HIV-1 and its impact on treatment success', Virology Journal, 6, pp. 184, http://www.virologyj.com/content/6/1/184

Millington ML; Arndt A; Boyd MP; Applegate TL; Shen SW, 2009, 'Towards a clinically relevant lentiviral transduction protocol for primary human CD34 hematopoietic stem/progenitor cells', PLoS One, 4, pp. e6461

Mcintyre GJ; Groneman JL; Tran A; Applegate TL, 2008, 'An infinitely expandable cloning strategy plus repeat-proof PCR for working with multiple shRNA', PLoS ONE, 3, http://dx.doi.org/10.1371/journal.pone.0003827

Mokany E; Todd AV; Fuery CJ; Applegate TL, 2006, 'Diagnosis and monitoring of PML-RARalpha-positive acute promyelocytic leukemia by quantitative RT-PCR.', Methods in molecular medicine, 125, pp. 127 - 147

Haber PS; Apte MV; Moran C; Applegate TL; Pirola RC; Korsten MA; Mccaughan GW; Wilson JS, 2004, 'Non-oxidative metabolism of ethanol by rat pancreatic acini', Pancreatology, 4, pp. 82 - 89, http://dx.doi.org/10.1159/000077608

Applegate TL; Iland HJ; Mokany E; Todd AV, 2002, 'Molecular monitoring of acute promyelocytic leukemia by DzyNA reverse transcription-PCR', CLINICAL CHEMISTRY, 48, pp. 1858 - 1860, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000178238100041&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Applegate TL; Iland HJ; Mokany E; Todd AV, 2002, 'Diagnosis and molecular monitoring of acute promyelocytic leukemia using DzyNA reverse transcription-PCR to quantify PML/RARα fusion transcripts', Clinical Chemistry, 48, pp. 1338 - 1343, http://dx.doi.org/10.1093/clinchem/48.8.1338

End DW; Smets G; Todd AV; Applegate TL; Fuery CJ; Angibaud P; Venet M; Sanz G; Poignet H; Skrzat S; Devine A; Wouters W; Bowden C, 2001, 'Characterization of the antitumor effects of the selective farnesyl protein transferase inhibitor R115777 in vivo and in vitro', Cancer Research, 61, pp. 131 - 137

Impey HL; Applegate TL; Haughton MA; Fuery CJ; King JE; Todd AV, 2000, 'Factors that influence deoxyribozyme cleavage during polymerase chain reaction', Analytical Biochemistry, 286, pp. 300 - 303, http://dx.doi.org/10.1006/abio.2000.4818

Todd AV; Fuery CJ; Impey HL; Applegate TL; Haughton MA, 2000, 'DzyNA-PCR: Use of DNAzymes to detect and quantify nucleic acid sequences in a real-time fluorescent format', Clinical Chemistry, 46, pp. 625 - 630, http://dx.doi.org/10.1093/clinchem/46.5.625

Fuery CJ; Impey H; Roberts NK; Applegate TL; Ward RL; Hawkins NJ; Sheehan C; O Grady R; Todd AV, 2000, 'Detection of rare mutant alleles by restriction endonuclease-mediated selective-PCR: assay design and optimization', Clinical Chemistry, 46, pp. 620 - 624

Ward RL; Sheehan C; Norrie M; Applegate TL; Fuery CJ; Impey H; Hawkins NJ; Todd AV, 2000, 'Factors influencing the detection of mutant K-ras in the serum of patients with colorectal cancer', Annals of the New York Academy of Sciences, 906, pp. 17 - 18, http://dx.doi.org/10.1111/j.1749-6632.2000.tb06583.x

Roberts NJ; Impey H; Applegate TL; Furey C; Ward RL; Todd AV, 1999, 'Rapid and sensitive detection of mutant alleles in codon 12 of K-ras by restriction endonuclease-mediated selective polymerase chain reaction (REMS-PCR)', BioTechniques, 27, pp. 418 - 422

Haber PS; Apte MV; Applegate TL; Norton ID; Korsten MA; Pirola RC; Wilson JS, 1998, 'Metabolism of ethanol by rat pancreatic acinar cells', Journal of Laboratory and Clinical Medicine, 132, pp. 294 - 302, http://dx.doi.org/10.1016/S0022-2143(98)90042-7

Haber PS; Apte MV; Applegate TL; Norton ID; Korsten MA; Pirola R; Wilson JS, 1998, 'Metabolism of ethanol by rat pancreatic acinar cells', Journal of Laboratory and Clinical Medicine, 132, pp. 203 - 294, http://linkinghub.elsevier.com/retrieve/pii/S0022-2143(98)90042-7

Apte MV; Haber PS; Applegate TL; Norton ID; Mccaughan GW; Korsten MA; Pirola RC; Wilson JS, 1998, 'Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture', Gut, pp. 128 - 133, http://dx.doi.org/10.1136/gut.43.1.128

Apte MV; Norton ID; Haber PS; Applegate TL; Mccaughan GW; Korsten MA; Pirola RC; Wilson JS, 1998, 'The effect of ethanol on pancreatic enzymes - a dietary artefact?', Biochimica et Biophysica ACTA, 1379, pp. 314 - 324, http://dx.doi.org/10.1016/S0304-4165(97)00109-8

Applegate TL; Karjalainen A; Bygrave FL, 1997, 'Rapid Ca²⁺ influx induced by the action of dibutylhydroquinone and glucagon in the perfused rat liver', Biochemical Journal, 323, pp. 463 - 467, http://dx.doi.org/10.1042/bj3230463

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