Select Publications

Journal articles

Liu T, 2012, 'Amide-based derivatives of â-alanine hydroxamic acid as histone deacetylase inhibitors: Attenuation of potency through resonance effects', Bioorganic and Medicinal Chemistry Letters, 22, pp. 6200 - 6204, http://dx.doi.org/10.1016/j.bmcl.2012.08.006

Liu T; Marshall G; Iismaa S; Liu P; Xu N, 2012, 'Enhancing the anticancer effect of the histone deacetylase inhibitor by activating transglutaminase', European Journal of Cancer, 48, pp. 3278 - 3287, http://dx.doi.org/10.1016/j.ejca.2012.02.067

Tay KH; Jin L; Tseng H; Jiang CC; Ye Y; Thorne RF; Liu T; Guo ST; Verrills NM; Hersey P; Zhang XD, 2012, 'Suppression of PP2A is critical for protection of melanoma cells upon endoplasmic reticulum stress', Cell Death & Disease, 3, pp. e337, http://dx.doi.org/10.1038/cddis.2012.79

Marshall GM; Liu PY; Gherardi S; Scarlett CJ; Bedalov A; Xu N; Iraci N; Valli E; Ling D; Thomas W; Van bekkum M; Sekyere E; Jankowski K; Trahair T; Mackenzie K; Haber M; Norris MD; Biankin AV; Perini G; Liu T, 2011, 'SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability', PLOS Genetics, 7, pp. e1 - e14, http://dx.doi.org/10.1371/journal.pgen.1002135

Liu T, 2011, 'The histone deacetylase SIRT1 promotes N-Myc-induced neuroblastoma by stabilizing N-Myc protein', PLoS Genetics, 7, pp. e1002135

Bell E; Chen L; Liu T; Marshall GM; Lunec J; Tweddle DA, 2010, 'MYCN oncoprotein targets and their therapeutic potential', Cancer Letters, 293, pp. 144 - 157, http://dx.doi.org/10.1016/j.canlet.2010.01.015

Liu T, 2010, 'Opposing Effects of Two Tissue Transglutaminase Protein Isoforms in Neuroblastoma Cell Differentiation', The Journal of Biological Chemistry, 285, pp. 3561 - 3567, http://dx.doi.org/10.1074/jbc.M109.053041

Marshall GM; Gherardi S; Xu N; Neiron Z; Trahair TN; Scarlett CJ; Chang DK; Liu PY; Jankowski K; Iraci N; Haber M; Norris MD; Keating J; Sekyere E; Jonquieres G; Biankin AV; Stossi F; Katzenellenbogen BS; Perini G; Liu T, 2010, 'Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects', Oncogene, 29, pp. 5957 - 5968, http://dx.doi.org/10.1038/onc.2010.332

Liu T; Bell J; Koach J; Malyukova A; Thomas W; Sekyere E; Cunningham A; Norris M; Haber M; Kavallaris M; Cheung B-B; Kim P; Tan O; Marshall G, 2010, 'TRIM16 acts as a tumour suppressor by inhibitory effects on cytoplasmic vimentin and nuclear E2F1 in neuroblastoma cells', Oncogene, 29, pp. 6172 - 6183, http://dx.doi.org/10.1038/onc.2010.340

Liu T, 2009, 'Over-expression of clusterin is a resistance factor to the anti-cancer effect of histone deacetylase inhibitors', European Journal of Cancer, 45, pp. 1846 - 1854, http://dx.doi.org/10.1016/j.ejca.2009.03.002

Liu T, 2009, 'The critical role of the class III histone deacetylase SIRT1 in cancer', Cancer Research, 69, pp. 1702 - 1705, http://dx.doi.org/10.1158/0008-5472.CAN-08-3365

Liu T, 2009, 'The cyclin-dependent kinase inhibitor, p21WAF1, promotes angiogenesis by repressing gene transcription of thioredoxin-binding protein 2 in cancer cells', Carcinogenesis, 30, pp. 1865 - 1871, http://dx.doi.org/10.1093/carcin/bgp225

Liu T; Tee AEL; Porro A; Smith SA; Dwarte T; Pei YL; Iraci N; Sekyere E; Haber M; Norris MD; Diolaiti D; Della Valle G; Perini G; Marshall GM, 2007, 'Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis (Proceedings of the National Academy of Science of the United States of America (November 20, 2007) 104; 47, (18682-18687) DOI: 10.1073/pnas.0705524104)', Proceedings of the National Academy of Sciences of the United States of America, 104, pp. 21021, http://dx.doi.org/10.1073/pnas.0711060105

Liu T; Tee EL; Porro A; Smith SA; Dwarte T; Norris MD; Diolaiti D; Della Valle G; Perini G; Marshall GM, 2007, 'Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis (vol 104, pg 18682, 2007)', PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 104, pp. 21021 - 21021, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000252077400076&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Liu T; Tee AEL; Porro A; Smith SA; Dwarte T; Pei YL; Iraci N; Sekyere E; Haber M; Norris MD; Diolaiti D; Della Valle G; Perini G; Marshall GM, 2007, 'Erratum: Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis (Proceedings of the National Academy of Sciences of the United States of America (2007) 104 (18682-18687) DOI: 10.1073/pnas.0705524104)', Proceedings of the National Academy of Sciences of the United States of America, 120, http://dx.doi.org/10.1073/pnas.2220015120

Liu T, 2007, 'Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis', Proceedings of the National Academy of Sciences of the United States of America, 104, pp. 18682 - 18687, http://dx.doi.org/10.1073/pnas.0705524104

Liu T; Kuljaca S; Haber M; Norris M; Marshall G; Dwarte T; Tee ANDREW, 2007, 'Enhancing the anti-angiogenic action of histone deacetylase inhibitors', Molecular Cancer, 6, pp. 68 - 79, http://dx.doi.org/10.1186/1476-4598-6-68

Liu T, 2006, 'Histone deacetylase inhibitors: multifunctional anticancer agents', Cancer Treatment Reviews, 32, pp. 157 - 165, http://dx.doi.org/10.1016/j.ctrv.2005.12.006

Liu T, 2005, 'The propeptide mediates formation of stromal stores of ProMIC-1: role in determining prostate cancer outcome', Cancer Research, 65, pp. 2330 - 2336, http://dx.doi.org/10.1158/0008-5472.CAN-04-3827

Liu T; Bohlken A; Kuljaca S; Lee M; Nguyen T; Norris M; Haber M; Marshall G; Smith S; Cheung B-B; Bowtell D, 2005, 'The retinoid anticancer signal: mechanisms of target gene regulation', British Journal of Cancer, 93, pp. 310 - 318, http://dx.doi.org/10.1038/sj.bjc.6602700

Liu T, 2003, 'Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum', Proceedings of the National Academy of Sciences of the United States of America, 100, pp. 3410 - 3415, http://dx.doi.org/10.1073/pnas.0530278100

Liu T; Bauskin AR; Zaunders J; Brown DA; Pankhurst S; Russell PJ; Breit SN, 2003, 'Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells', Cancer research, 63, pp. 5034 - 5040

Brown DA; Ward RL; Buckhaults P; Liu T; Romans KE; Hawkins NJ; Bauskin AR; Kinzler KW; Vogelstein B; Breit SN, 2003, 'MIC 1 serum level and genotype: Associations with progress and prognosis of colorectal carcinoma', Clinical Cancer Research, 9, pp. 2642 - 2650

Liu T, 2002, 'Antibody-based approach to high-volume genotyping for MIC-1 polymorphism', BioTechniques, 33, pp. 118 - 120

Liu T, 2002, 'Concentration in plasma of macrophage inhibitory cytokine-1 and risk of cardiovascular events in women: a nested case-control study', Lancet, 359, pp. 2159 - 2163, http://dx.doi.org/10.1016/S0140-6736(02)09093-1

Liu T; Tracey DJ, 2000, 'ATP P2X receptors play little role in the maintenance of neuropathic hyperalgesia', Neuroreport, 11, pp. 1272 - 1669

Liu T; Van Roogen N; Tracey DJ, 2000, 'Depletion of macrophages reduces axonal degeneration and hyperalgesia following nerve injury', Pain, pp. 25 - 32

Liu T; Knight KR; Tracey DJ, 2000, 'Hyperalgesia due to nerve injury - role of peroxynitrite', Neuroscience, pp. 125 - 131

Tao L; Walker JS; Tracey DJ, 1999, 'Zinc alleviates thermal hyperalgesia due to partial nerve injury', NeuroReport, 10, pp. 645 - 649, http://dx.doi.org/10.1097/00001756-199902250-00037

Khalil Z; Liu T; Helme RD, 1999, 'Free radicals contribute to the reduction in peripheral vascular responses and the maintenance of thermal hyperalgesia in rats with chronic constriction injury', Pain, 79, pp. 31 - 37, http://dx.doi.org/10.1016/S0304-3959(98)00143-2

Liu T; Walker JS; Tracey DJ, 1999, 'Zinc alleviates thermal hyperalgesia due to partial nerve injury', Neuroreport, 10, pp. 1619 - 1623


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