Select Publications

Journal articles

Mewton L;Reppermund S;Crawford J;Bunce D;Wen W;Sachdev P, 2018, 'Cross-sectional and prospective inter-relationships between depressive symptoms, vascular disease and cognition in older adults', Psychological Medicine, pp. 1 - 9,

Jiang J;Paradise M;Liu T;Armstrong NJ;Zhu W;Kochan NA;Brodaty H;Sachdev PS;Wen W, 2018, 'The association of regional white matter lesions with cognition in a community-based cohort of older individuals', NeuroImage. Clinical, vol. 19, pp. 14 - 21,

Paradise MB;Shepherd CE;Wen W;Sachdev PS, 2018, 'Neuroimaging and neuropathology indices of cerebrovascular disease burden', Neurology, vol. 91, pp. 310 - 320,

Taylor ME;Lord SR;Delbaere K;Wen W;Jiang J;Brodaty H;Kurrle SE;Stefanie Mikolaizak A;Close JC T, 2018, 'White matter hyperintensities are associated with falls in older people with dementia', Brain Imaging and Behavior,

Cvejic RC;Hocking DR;Wen W;Georgiou-Karistianis N;Cornish KM;Godler DE;Rogers C;Trollor JN, 2018, 'Reduced caudate volume and cognitive slowing in men at risk of fragile X-associated tremor ataxia syndrome', Brain Imaging and Behavior,

Kong XZ;Mathias SR;Guadalupe T;Abé C;Agartz I;Akudjedu TN;Aleman A;Alhusaini S;Allen NB;Ames D;Andreassen OA;Vasquez AA;Armstrong NJ;Bergo F;Bastin ME;Batalla A;Bauer J;Baune BT;Baur-Streubel R;Biederman J;Blaine SK;Boedhoe P;Bøen E;Bose A;Bralten J;Brandeis D;Brem S;Brodaty H;Yüksel D;Brooks SJ;Buitelaar J;Bürger C;Bülow R;Calhoun V;Calvo A;Canales-Rodríguez EJ;Canive JM;Cannon DM;Caparelli EC;Castellanos FX;Cavalleri GL;Cendes F;Chaim-Avancini TM;Chantiluke K;Chen QL;Chen X;Cheng Y;Christakou A;Clark VP;Coghill D;Connolly CG;Conzelmann A;Córdova-Palomera A;Cousijn J;Crow T;Cubillo A;Dale A;Dannlowski U;De Bruttopilo SA;De Zeeuw P;Deary IJ;Delanty N;Demeter DV;Di Martino A;Dickie EW, 2018, 'Mapping cortical brain asymmetry in 17,141 healthy individuals worldwide via the ENIGMA consortium', Proceedings of the National Academy of Sciences of the United States of America, vol. 115, pp. E5154 - E5163,

Paradise M;Seruga A;Crawford JD;Chaganti J;Thalamuthu A;Kochan NA;Brodaty H;Wen W;Sachdev PS, 2018, 'The relationship of cerebral microbleeds to cognition and incident dementia in non-demented older individuals', Brain Imaging and Behavior, pp. 1 - 12,

Zimmermann J;Perry A;Breakspear M;Schirner M;Sachdev P;Wen W;Kochan NA;Mapstone M;Ritter P;McIntosh AR;Solodkin A, 2018, 'Differentiation of Alzheimer's disease based on local and global parameters in personalized Virtual Brain models', NeuroImage: Clinical, vol. 19, pp. 240 - 251,

Hyett MP;Perry A;Breakspear M;Wen W;Parker GB, 2018, 'White matter alterations in the internal capsule and psychomotor impairment in melancholic depression', PLoS ONE, vol. 13,

Jiang J;Liu T;Zhu W;Koncz R;Liu H;Lee T;Sachdev PS;Wen W, 2018, 'UBO Detector – A cluster-based, fully automated pipeline for extracting white matter hyperintensities', NeuroImage, vol. 174, pp. 539 - 549,

Jiang J;Thalamuthu A;Ho JE;Mahajan A;Ek WE;Brown DA;Breit SN;Wang TJ;Gyllensten U;Chen MH;Enroth S;Januzzi JL;Lind L;Armstrong NJ;Kwok JB;Schofield PR;Wen W;Trollor JN;Johansson Å;Morris AP;Vasan RS;Sachdev PS;Mather KA, 2018, 'A meta-analysis of genome-wide association studies of growth differentiation factor-15 concentration in blood', Frontiers in Genetics, vol. 9,

Zhang H;Sachdev PS;Thalamuthu A;He Y;Xia M;Kochan NA;Crawford JD;Trollor JN;Brodaty H;Wen W, 2018, 'The relationship between voxel-based metrics of resting state functional connectivity and cognitive performance in cognitively healthy elderly adults', Brain Imaging and Behavior, pp. 1 - 17,

Ghanavati T;Smitt MS;Lord SR;Sachdev P;Wen W;Kochan NA;Brodaty H;Delbaere K, 2018, 'Deep white matter hyperintensities, microstructural integrity and dual task walking in older people', Brain Imaging and Behavior, pp. 1 - 9,

Shen X;Liu T;Tao D;Fan Y;Zhang J;Li S;Jiang J;Zhu W;Wang Y;Wang Y;Brodaty H;Sachdev P;Wen W, 2018, 'Variation in longitudinal trajectories of cortical sulci in normal elderly', NeuroImage, vol. 166, pp. 1 - 9,

Koncz R;Mohan A;Dawes L;Thalamuthu A;Wright M;Ames D;Lee T;Trollor J;Wen W;Sachdev P, 2018, 'Incidental findings on cerebral MRI in twins: the Older Australian Twins Study', Brain Imaging and Behavior, vol. 12, pp. 860 - 869,

Shan X;Wen W;Yan T;Cheng W;Huang Z;Zhang L;Zhang H;Wang T;Zhu W;Zhu Y;Zhu J, 2017, 'miR 1296-5p inhibits the migration and invasion of gastric cancer cells by repressing erbb2 expression', PLoS ONE, vol. 12,

Zhou X;Wen W;Shan X;Zhu W;Xu J;Guo R;Cheng W;Wang F;Qi LW;Chen Y;Huang Z;Wang T;Zhu D;Liu P;Shu Y, 2017, 'A six-microRNA panel in plasma was identified as a potential biomarker for lung adenocarcinoma diagnosis', Oncotarget, vol. 8, pp. 6513 - 6525,

Zhou X;Wen W;Zhu J;Huang Z;Zhang L;Zhang H;Qi LW;Shan X;Wang T;Cheng W;Zhu D;Yin Y;Chen Y;Zhu W;Shu Y;Liu P, 2017, 'A six-microRNA signature in plasma was identified as a potential biomarker in diagnosis of esophageal squamous cell carcinoma', Oncotarget, vol. 8, pp. 34468 - 34480,

Guan H;Liu T;Jiang J;Tao D;Zhang J;Niu H;Zhu W;Wang Y;Cheng J;Kochan NA;Brodaty H;Sachdev P;Wen W, 2017, 'Classifying MCI subtypes in community-dwelling elderly using cross-sectional and longitudinal MRI-based biomarkers', Frontiers in Aging Neuroscience, vol. 9,

Perry A;Wen W;Kochan NA;Thalamuthu A;Sachdev PS;Breakspear M, 2017, 'The independent influences of age and education on functional brain networks and cognition in healthy older adults', Human Brain Mapping, vol. 38, pp. 5094 - 5114,

Brouwer RM;Panizzon MS;Glahn DC;Hibar DP;Hua X;Jahanshad N;Abramovic L;de Zubicaray GI;Franz CE;Hansell NK;Hickie IB;Koenis MM G;Martin NG;Mather KA;McMahon KL;Schnack HG;Strike LT;Swagerman SC;Thalamuthu A;Wen W;Gilmore JH;Gogtay N;Kahn RS;Sachdev PS;Wright MJ;Boomsma DI;Kremen WS;Thompson PM;Hulshoff Pol HE, 2017, 'Genetic influences on individual differences in longitudinal changes in global and subcortical brain volumes: Results of the ENIGMA plasticity working group', Human Brain Mapping, vol. 38, pp. 4444 - 4458,

Haynes BI;Bunce D;Kochan NA;Wen W;Brodaty H;Sachdev PS, 2017, 'Associations between reaction time measures and white matter hyperintensities in very old age', Neuropsychologia, vol. 96, pp. 249 - 255,

Cai K;Xu H;Guan H;Zhu W;Jiang J;Cui Y;Zhang J;Liu T;Wen W, 2017, 'Identification of early-stage Alzheimer's disease using sulcal morphology and other common neuroimaging indices', PLoS ONE, vol. 12,

Hibar DP;Adams HH H;Jahanshad N;Chauhan G;Stein JL;Hofer E;Renteria ME;Bis JC;Arias-Vasquez A;Ikram MK;Desrivières S;Vernooij MW;Abramovic L;Alhusaini S;Amin N;Andersson M;Arfanakis K;Aribisala BS;Armstrong NJ;Athanasiu L;Axelsson T;Beecham AH;Beiser A;Bernard M;Blanton SH;Bohlken MM;Boks MP;Bralten J;Brickman AM;Carmichael O;Chakravarty MM;Chen Q;Ching CR K;Chouraki V;Cuellar-Partida G;Crivello F;Den Braber A;Doan NT;Ehrlich S;Giddaluru S;Goldman AL;Gottesman RF;Grimm O;Griswold ME;Guadalupe T;Gutman BA;Hass J;Haukvik UK;Hoehn D;Holmes AJ;Hoogman M;Janowitz D;Jia T;Jørgensen KN;Karbalai N;Kasperaviciute D;Kim S;Klein M;Kraemer B;Lee PH, 2017, 'Novel genetic loci associated with hippocampal volume', Nature Communications, vol. 8,

Mavros Y;Gates N;Wilson GC;Jain N;Meiklejohn J;Brodaty H;Wen W;Singh N;Baune BT;Suo C;Baker MK;Foroughi N;Wang Y;Sachdev PS;Valenzuela M;Fiatarone Singh MA, 2017, 'Mediation of Cognitive Function Improvements by Strength Gains After Resistance Training in Older Adults with Mild Cognitive Impairment: Outcomes of the Study of Mental and Resistance Training', Journal of the American Geriatrics Society, vol. 65, pp. 550 - 559,

Suo C;Gates N;Fiatarone Singh M;Saigal N;Wilson GC;Meiklejohn J;Sachdev P;Brodaty H;Wen W;Singh N;Baune BT;Baker M;Foroughi N;Wang Y;Valenzuela MJ, 2017, 'Midlife managerial experience is linked to late life hippocampal morphology and function', Brain Imaging and Behavior, vol. 11, pp. 333 - 345,

Hocking DR;Birch RC;Bui QM;Menant JC;Lord SR;Georgiou-Karistianis N;Godler DE;Wen W;Hackett A;Rogers C;Trollor JN, 2017, 'Cerebellar volume mediates the relationship between FMR1 mRNA levels and voluntary step initiation in males with the premutation', Neurobiology of Aging, vol. 50, pp. 5 - 12,

Birch RC;Hocking DR;Cornish KM;Menant JC;Lord SR;Georgiou-Karistianis N;Godler DE;Wen W;Rogers C;Trollor JN, 2017, 'Selective subcortical contributions to gait impairments in males with the FMR1 premutation', Journal of Neurology, Neurosurgery and Psychiatry, vol. 88, pp. 188 - 190,

Guadalupe T;Mathias SR;VanErp TG M;Whelan CD;Zwiers MP;Abe Y;Abramovic L;Agartz I;Andreassen OA;Arias-Vásquez A;Aribisala BS;Armstrong NJ;Arolt V;Artiges E;Ayesa-Arriola R;Baboyan VG;Banaschewski T;Barker G;Bastin ME;Baune BT;Blangero J;Bokde AL W;Boedhoe PS W;Bose A;Brem S;Brodaty H;Bromberg U;Brooks S;Büchel C;Buitelaar J;Calhoun VD;Cannon DM;Cattrell A;Cheng Y;Conrod PJ;Conzelmann A;Corvin A;Crespo-Facorro B;Crivello F;Dannlowski U;de Zubicaray GI;de Zwarte SM C;Deary IJ;Desrivières S;Doan NT;Donohoe G;Dørum ES;Ehrlich S;Espeseth T;Fernández G;Flor H;Fouche JP;Frouin V;Fukunaga M;Gallinat J;Garavan H;Gill M;Suarez AG;Gowland P;Grabe HJ;Grotegerd D;Gruber O;Hagenaars S;Hashimoto R, 2016, 'Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex', Brain Imaging and Behavior, pp. 1 - 18,

Adams HH H;Hibar DP;Chouraki V;Stein JL;Nyquist PA;Rentería ME;Trompet S;Arias-Vasquez A;Seshadri S;Desrivières S;Beecham AH;Jahanshad N;Wittfeld K;Van Der Lee SJ;Abramovic L;Alhusaini S;Amin N;Andersson M;Arfanakis K;Aribisala BS;Armstrong NJ;Athanasiu L;Axelsson T;Beiser A;Bernard M;Bis JC;Blanken LM E;Blanton SH;Bohlken MM;Boks MP;Bralten J;Brickman AM;Carmichael O;Chakravarty MM;Chauhan G;Chen Q;Ching CR K;Cuellar-Partida G;Braber AD;Doan NT;Ehrlich S;Filippi I;Ge T;Giddaluru S;Goldman AL;Gottesman RF;Greven CU;Grimm O;Griswold ME;Guadalupe T;Hass J;Haukvik UK;Hilal S;Hofer E;Hoehn D;Holmes AJ;Hoogman M;Janowitz D;Jia T, 2016, 'Novel genetic loci underlying human intracranial volume identified through genome-wide association', Nature Neuroscience, vol. 19, pp. 1569 - 1582,

Wen W;Thalamuthu A;Mather KA;Zhu W;Jiang J;De Micheaux PL;Wright MJ;Ames D;Sachdev PS, 2016, 'Distinct Genetic Influences on Cortical and Subcortical Brain Structures', Scientific Reports, vol. 6,

Roberts G;Wen W;Frankland A;Perich T;Holmes-Preston E;Levy F;Lenroot RK;Hadzi-Pavlovic D;Nurnberger JI;Breakspear M;Mitchell PB, 2016, 'Interhemispheric white matter integrity in young people with bipolar disorder and at high genetic risk', Psychological Medicine, vol. 46, pp. 2385 - 2396,

Sachdev PS;Thalamuthu A;Mather KA;Ames D;Wright MJ;Wen W;Bowden J;Lee T;Brodaty H;Crawford J;Duckworth T;Kang K;Garden N;Martin N;Lemmon C, 2016, 'White Matter Hyperintensities Are under Strong Genetic Influence', Stroke, vol. 47, pp. 1422 - 1428,

Suo C;Singh MF;Gates N;Wen W;Sachdev P;Brodaty H;Saigal N;Wilson GC;Meiklejohn J;Singh N;Baune BT;Baker M;Foroughi N;Wang Y;Mavros Y;Lampit A;Leung I;Valenzuela MJ, 2016, 'Therapeutically relevant structural and functional mechanisms triggered by physical and cognitive exercise', Molecular Psychiatry,

Roberts G;Lenroot R;Frankland A;Yeung PK;Gale N;Wright A;Lau P;Levy F;Wen W;Mitchell PB, 2016, 'Abnormalities in left inferior frontal gyral thickness and parahippocampal gyral volume in young people at high genetic risk for bipolar disorder', Psychological Medicine, vol. 46, pp. 2083 - 2096,

Suo C;Singh MF;Gates N;Wen W;Sachdev P;Brodaty H;Saigal N;Wilson GC;Meiklejohn J;Singh N;Baune BT;Baker M;Foroughi N;Wang Y;Mavros Y;Lampit A;Leung I;Valenzuela MJ, 2016, 'Therapeutically relevant structural and functional mechanisms triggered by physical and cognitive exercise', Molecular Psychiatry, vol. 21, pp. 1633 - 1642,

Lupton MK;Strike L;Hansell NK;Wen W;Mather KA;Armstrong NJ;Thalamuthu A;McMahon KL;de Zubicaray GI;Assareh AA;Simmons A;Proitsi P;Powell JF;Montgomery GW;Hibar DP;Westman E;Tsolaki M;Kloszewska I;Soininen H;Mecocci P;Velas B;Lovestone S;Brodaty H;Ames D;Trollor JN;Martin NG;Thompson PM;Sachdev PS;Wright MJ, 2016, 'The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume', Neurobiology of Aging, vol. 40, pp. 68 - 77,

Poljak A;Crawford JD;Smythe GA;Brodaty H;Slavin MJ;Kochan NA;Trollor JN;Wen W;Mather KA;Assareh AA;Ng PC;Sachdev PS, 2016, 'The relationship between plasma aβ levels, cognitive function and brain volumetrics: Sydney memory and ageing study', Current Alzheimer Research, vol. 13, pp. 243 - 255,

Yang Z;Wen W;Jiang J;Crawford JD;Reppermund S;Levitan C;Slavin MJ;Kochan NA;Richmond RL;Brodaty H;Trollor JN;Sachdev PS, 2016, 'Structural MRI biomarkers of mild cognitive impairment from young elders to centenarians', Current Alzheimer Research, vol. 13, pp. 256 - 267,

Yang Z;Wen W;Jiang J;Crawford JD;Reppermund S;Levitan C;Slavin MJ;Kochan NA;Richmond RL;Brodaty H;Trollor JN;Sachdev PS, 2016, 'Age-associated differences on structural brain MRI in nondemented individuals from 71 to 103 years', Neurobiology of Aging, vol. 40, pp. 86 - 97,

Franke B;van Hulzen KJ E;Arias-Vasquez A;Bralten J;Hoogman M;Klein M;van Donkelaar MM J;Hakobjan MM H;Heister AJ G A M;Makkinje RR R;Naber MA M;van der Marel SS L;Mostert JC;Brunner HG;van Bokhoven H;Zwiers MP;Buitelaar JK;Fernández G;Fisher SE;Francks C;Stein JL;Hibar DP;Thompson PM;Ripke S;Anttila V;Neale BM;Farh KH;Bulik-Sullivan B;Huang H;Fromer M;Goldstein JI;Daly MJ;Walters RK, 2016, 'Genetic influences on schizophrenia and subcortical brain volumes: Large-scale proof of concept', Nature Neuroscience, vol. 19, pp. 420 - 431,

Jiang J;Wen W;Sachdev PS, 2016, 'Macrophage inhibitory cytokine-1/growth differentiation factor 15 as a marker of cognitive ageing and dementia', Current Opinion in Psychiatry, vol. 29, pp. 181 - 186,

Zhou X;Wen W;Shan X;Qian J;Li H;Jiang T;Wang W;Cheng W;Wang F;Qi L;Ding Y;Liu P;Zhu W;Chen Y, 2015, 'MiR-28-3p as a potential plasma marker in diagnosis of pulmonary embolism', Thrombosis Research, vol. 138, pp. 91 - 95,

Zhou X;Zhu W;Li H;Wen W;Cheng W;Wang F;Wu Y;Qi L;Fan Y;Chen Y;Ding Y;Xu J;Qian J;Huang Z;Wang T;Zhu D;Shu Y;Liu P, 2015, 'Diagnostic value of a plasma microRNA signature in gastric cancer: A microRNA expression analysis', Scientific Reports, vol. 5,

Zhang H;Sachdev PS;Wen W;Crawford JD;Brodaty H;Baune BT;Kochan NA;Slavin MJ;Reppermund S;Kang K;Trollor JN, 2015, 'The relationship between inflammatory markers and voxel-based gray matter volumes in nondemented older adults', Neurobiology of Aging,

Tuerk C;Zhang H;Sachdev P;Lord SR;Brodaty H;Wen W;Delbaere K, 2015, 'Regional Gray Matter Volumes Are Related to Concern about Falling in Older People: A Voxel-Based Morphometric Study', Journals of Gerontology - Series A Biological Sciences and Medical Sciences, vol. 71, pp. 138 - 144,

Jiang J;Trollor JN;Brown DA;Crawford JD;Thalamuthu A;Smith E;Breit SN;Liu T;Brodaty H;Baune BT;Sachdev PS;Wen W, 2015, 'An inverse relationship between serum macrophage inhibitory cytokine-1 levels and brain white matter integrity in community-dwelling older individuals', Psychoneuroendocrinology, vol. 62, pp. 80 - 88,

Fiatarone Singh MA;Gates N;Saigal N;Wilson GC;Meiklejohn J;Brodaty H;Wen W;Singh N;Baune BT;Suo C;Baker MK;Foroughi N;Wang Y;Sachdev PS;Valenzuela M, 2015, 'Reply to the Letter to the Editor by O'Caoimh et al', Journal of the American Medical Directors Association, vol. 16, pp. 999 - 1001,

Boraxbekk CJ;Ames D;Kochan NA;Lee T;Thalamuthu A;Wen W;Armstrong NJ;Kwok JB J;Schofield PR;Reppermund S;Wright MJ;Trollor JN;Brodaty H;Sachdev P;Mather KA, 2015, 'Investigating the influence of KIBRA and CLSTN2 genetic polymorphisms on cross-sectional and longitudinal measures of memory performance and hippocampal volume in older individuals', Neuropsychologia, vol. 78, pp. 10 - 17,

Perry A;Wen W;Lord A;Thalamuthu A;Roberts G;Mitchell PB;Sachdev PS;Breakspear M, 2015, 'The organisation of the elderly connectome', NeuroImage, vol. 114, pp. 414 - 426,

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