By Conjoint Professor Samuel Norbert Breit

Journal articles

Walker B, 2000, 'Comparative effects of azimilide and ambasilide on the human ether-a-go-go-related gene (HERG) potassium channel', Cardiovascular Research, 48, pp. 44 - 58, http://dx.doi.org/10.1016/s0008-6363(00)00155-3

Fairlie WD; Zhang H-P; Brown PK; Russell PK; Bauskin AR; Breit SN, 2000, 'Expression of a TGF-β superfamily protein, macrophage inhibitory cytokine-1, in the yeast Pichia pastoris', Gene, 254, pp. 67 - 76, http://dx.doi.org/10.1016/s0378-1119(00)00295-x

Tonini R; Ferroni A; Valenzuela SM; Warton K; Campbell TJ; Breit SN; Mazzanti M, 2000, 'Functional characterization of the NCC27 nuclear protein in stable transfected CHO-K1 cells', FASEB JOURNAL, 14, pp. 1171 - 1178, http://dx.doi.org/10.1096/fasebj.14.9.1171

Walker BD; Tie H; Singleton CB; Bursill JA; Wyse KR; Valenzuela SM; Breit SN; Campbell TJ, 2000, 'Hyperkalaemia and acidosis modify HERG channel biophysical properties and antagonise inhibition by sotalol', Heart, Lung and Circulation, 9, pp. A131 - A131, http://dx.doi.org/10.1046/j.1443-9506.2000.07650.x

Tie H; Walker BD; Singleton CB; Valenzuela SM; Bursill JA; Wyse KR; Breit SN; Campbell TJ, 2000, 'Inhibition of HERG potassium channels by the antimalarial agent halofantrine', British Journal of Pharmacology, 130, pp. 1967 - 1975, http://dx.doi.org/10.1038/sj.bjp.0703470

Singleton CB; Walker BD; Tie H; Bursill JA; Wyse KR; Valenzuela SM; Breit SN; Campbell TJ, 2000, 'Potent blockade by quinidine of the Kv4.3 current: Significance with regard to treatment of the brugada syndrome', Heart, Lung and Circulation, 9, pp. A92 - A92, http://dx.doi.org/10.1046/j.1443-9506.2000.06115.x

Tie H; Walker BD; Singleton CB; Bursill J; Wyse K; Valenzuela S; Breit SN; Campbell TJ, 2000, 'The antipsychotic agents thioridazine, chlorpromazine and clozapine block the human-ether-a-go-go-related gene (HERG) potassium channel: Cellular mechanism for proarrhythmia', Heart, Lung and Circulation, 9, pp. A109 - A109, http://dx.doi.org/10.1046/j.1443-9506.2000.06796.x

Tie H; Walker BD; Valenzuela SM; Breit SN; Campbell TJ, 2000, 'The heart of psychotropic drug therapy', The Lancet, 355, pp. 1825 - 1825, http://dx.doi.org/10.1016/s0140-6736(05)73083-x

Valenzuela SM; Mazzanti M; Tonini R; Qiu MR; Warton K; Musgrove EA; Campbell TJ; Breit SN, 2000, 'The nuclear chloride ion channel NCC27 is involved in regulation of the cell cycle', The Journal of Physiology, 529, pp. 541 - 552, http://dx.doi.org/10.1111/j.1469-7793.2000.00541.x

Breit S; Kolb HA; Häussinger D; Lang F, 1999, 'Effects of tetrabutylhydroperoxide on hepatocyte ion channels', Cellular Physiology and Biochemistry, 9, pp. 133 - 138, http://dx.doi.org/10.1159/000016310

Singleton CB; Valenzuela SM; Walker BD; Tie H; Wyse KR; Bursill JA; Qiu MR; Breit SN; Campbell TJ, 1999, 'Blockade by N-3 polyunsaturated fatty acid of the Kv4.3 current stably expressed in Chinese hamster ovary cells.', Br J Pharmacol, 127, pp. 941 - 948, http://dx.doi.org/10.1038/sj.bjp.0702638

Walker BD; Valenzuela SM; Singleton CB; Tie H; Bursill JA; Wyse KR; Qiu MR; Breit SN; Campbell TJ, 1999, 'Inhibition of HERG channels stably expressed in a mammalian cell line by the antianginal agent perhexiline maleate.', Br J Pharmacol, 127, pp. 243 - 251, http://dx.doi.org/10.1038/sj.bjp.0702502

Walker BD; Singleton CB; Bursill JA; Wyse KR; Valenzuela SM; Qiu MR; Breit SN; Campbell TJ, 1999, 'Inhibition of the human ether-a-go-go-related gene (HERG) potassium channel by cisapride: affinity for open and inactivated states.', Br J Pharmacol, 128, pp. 444 - 450, http://dx.doi.org/10.1038/sj.bjp.0702774

Fairlie WD; Moore AG; Bauskin AR; Russell PK; Zhang HP; Breit SN, 1999, 'MIC-1 is a novel TGF-beta superfamily cytokine associated with macrophage activation.', J Leukoc Biol, 65, pp. 2 - 5, http://dx.doi.org/10.1002/jlb.65.1.2

Fairlie WD; Russell PK; Zhang HP; Breit SN, 1999, 'Screening procedure for Pichia pastoris clones containing multiple copy gene inserts.', Biotechniques, 26, pp. 1042 - 1044, http://dx.doi.org/10.2144/99266bm06

Martin D; Bursill J; Qui MR; Breit SN; Campbell T, 1998, 'Alternative hypothesis for efficacy of macrolides in acute coronary syndromes.', Lancet, 351, pp. 1858 - 1859, http://dx.doi.org/10.1016/S0140-6736(05)78804-8

Breit S; Kolb HA; Apfel H; Haberland C; Schmitt M; Häussinger D; Graf J; Lang F, 1998, 'Regulation of ion channels in rat hepatocytes', Pflugers Archiv European Journal of Physiology, 435, pp. 203 - 210, http://dx.doi.org/10.1007/s004240050502

Bootcov MR; Bauskin AR; Valenzuela SM; Moore AG; Bansal M; He XY; Zhang HP; Donnellan M; Mahler S; Pryor K; Walsh BJ; Nicholson RC; Fairlie WD; Por SB; Robbins JM; Breit SN, 1997, 'MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-β superfamily', Proceedings of the National Academy of Sciences, 94, pp. 11514 - 11519, http://dx.doi.org/10.1073/pnas.94.21.11514

Valenzuela SM; Martin DK; Por SB; Robbins JM; Warton K; Bootcov MR; Schofield PR; Campbell TJ; Breit SN, 1997, 'Molecular Cloning and Expression of a Chloride Ion Channel of Cell Nuclei', Journal of Biological Chemistry, 272, pp. 12575 - 12582, http://dx.doi.org/10.1074/jbc.272.19.12575

Brown DA; Breit SN, 1997, 'Scleroderma Lung Disease', BioDrugs, 8, pp. 185 - 192, http://dx.doi.org/10.2165/00063030-199708030-00004

Breit SN, 1995, 'Clinical features of immunodeficiency in man', Human Experimental Toxicology, 14, pp. 95 - 97, http://dx.doi.org/10.1177/096032719501400120

Waldegger S; Beisse F; Apfel H; Breit S; Kolb HA; Häussinger D; Lang F, 1995, 'Electrophysiological effects of progesterone on hepatocytes', Biochimica Et Biophysica Acta Molecular Cell Research, 1266, pp. 186 - 190, http://dx.doi.org/10.1016/0167-4889(94)00236-8

Martin DJ; Bootcov MR; Campbell TJ; French PW; Breit SN, 1995, 'Human macrophages contain a stretch-sensitive potassium channel that is activated by adherence and cytokines', Journal of Membrane Biology, 147, pp. 305 - 315

Walsh BR; Gooley AA; Williams KM; Breit SN, 1995, 'Identification of macrophage activation associated proteins by two-dimensional gel electrophoresis and microsequencing', Journal of Leukocyte Biology, pp. 507 - 512

Morgan GW; Pharm B; Breit SN, 1995, 'Radiation and the lung: A reevaluation of the mechanisms mediating pulmonary injury', International Journal of Radiation Oncology*Biology*Physics, 31, pp. 361 - 369, http://dx.doi.org/10.1016/0360-3016(94)00477-3

Breit SN; Thornton SC; Penny R, 1994, 'Lung involvement in Scleroderma', Clinics in Dermatology, 12, pp. 243 - 252, http://dx.doi.org/10.1016/s0738-081x(94)90328-x

Bennett S; Breit SN, 1994, 'Variables in the isolation and culture of human monocytes that are of particular relevance to studies of HIV.', J Leukoc Biol, 56, pp. 236 - 240, http://dx.doi.org/10.1002/jlb.56.3.236

Schwartz DA; Burmeister LF; Hunninghake GW, 1993, 'Bronchoalveolar Lavage Cellularity: The Distribution in Normal Volunteers: Reply', American Review of Respiratory Disease, 147, pp. 1607 - 1608, http://dx.doi.org/10.1164/ajrccm/147.6_pt_1.1607a

Roberts CM; Foulcher E; Zaunders JJ; Bryant DH; Freund J; Cairns D; Penny R; Morgan GW; Breit SN, 1993, 'Radiation pneumonitis: a possible lymphocyte-mediated hypersensitivity reaction.', Ann Intern Med, 118, pp. 696 - 700, http://dx.doi.org/10.7326/0003-4819-118-9-199305010-00006

Bennett S; Por SB; Cooley MA; Breit SN, 1993, 'In vitro replication dynamics of human culture-derived macrophages in a long term serum-free system.', J Immunol, 150, pp. 2364 - 2371, https://www.ncbi.nlm.nih.gov/pubmed/7680690

Williams KM; Day RO; Breit SN, 1993, 'Biochemical actions and clinical pharmacology of anti-inflammatory drugs', Advances in Drug Research, 24, pp. 121 - 198

Roberts CM; Cairns D; Bryant DH; Burke WMJ; Yeates M; Blake H; Penny R; Shelley L; Zaunders JJ; Breit SN, 1993, 'Changes in epithelial lining fluid albumin associated with smoking and interstitial lung disease', European Respiratory Journal, 6, pp. 110 - 115

Kuschner WG; Brown JK; Kane GC; Breit SN, 1993, 'Quantifying lymphocytes in bronchoalveolar lavage fluid [2]', Annals of Internal Medicine, 119, pp. 1050 - 1051, http://dx.doi.org/10.7326/0003-4819-119-10-199311150-00019

Breit SN, 1993, 'Bronchoalveolar Lavage Cellularity: The Distribution in Normal Volunteers', American Review of Respiratory Disease, 147, pp. 1607 - 1607, http://dx.doi.org/10.1164/ajrccm/147.6_Pt_1.1607

Walsh BJ; Thornton SC; Penny R; Breit SN, 1992, 'Microplate reader-based quantitation of collagens', Analytical Biochemistry, 203, pp. 187 - 190, http://dx.doi.org/10.1016/0003-2697(92)90301-m

Katelaris A; Penny R; Breit SN, 1992, 'Mitotic Activity in the Dermis of Mice During Graft Versus Host Disease: The Role of Fibroblast Replication in Dermal Fibrosis', Journal of Investigative Dermatology, 99, pp. 779 - 783, http://dx.doi.org/10.1111/1523-1747.ep12614736

Bennett S; Por SB; Stanley ER; Breit SN, 1992, 'Monocyte proliferation in a cytokine-freem serum-free system', Journal of Immunological Methods, 153, pp. 201 - 212, http://dx.doi.org/10.1016/0022-1759(92)90323-l

Ramsay SC; Yeates MG; Burke WM; Bryant DH; Morgan GW; Breit SN, 1992, 'Quantitative pulmonary gallium scanning in interstitial lung disease.', Eur J Nucl Med, 19, pp. 80 - 85, http://dx.doi.org/10.1007/BF00184121

Ma J; Walsh B; Chen S-L; Penny R; Breit SN, 1992, 'Restoring antibody activity of a monoclonal anti-RNP antibody by dissociative HPLC demonstration of blocking antibody binding sites with antigen released from effete hybridoma cells', Journal of Immunological Methods, 155, pp. 121 - 127, http://dx.doi.org/10.1016/0022-1759(92)90278-2

Burke WM; Roberts CM; Bryant DH; Cairns D; Yeates M; Morgan GW; Martin BJ; Blake H; Penny R; Zaunders JJ, 1992, 'Smoking-induced changes in epithelial lining fluid volume, cell density and protein.', Eur Respir J, 5, pp. 780 - 784, https://www.ncbi.nlm.nih.gov/pubmed/1499700

Cairns D; Shelley L; Burke WM; Bryant DH; Yeates M; Penny R; Breit SN, 1992, 'The differing patterns of interstitial lung involvement in connective tissue diseases.', J Rheumatol, 19, pp. 1089 - 1095, https://www.ncbi.nlm.nih.gov/pubmed/1512763

Cairns D; Shelley L; Burke WMJ; Bryant DH; Yeates M; Morgan GW; Penny R; Breit SN, 1991, 'Interstitial Lung Disease Associated with Connective Tissue Diseases: The Use of Statistical Structure Analysis in Model Development', American Review of Respiratory Disease, 143, pp. 1235 - 1240, http://dx.doi.org/10.1164/ajrccm/143.6.1235

THORNTON SC; POR SB; PENNY R; RICHTER M; SHELLEY L; BREIT SN, 1991, 'Identification of the major fibroblast growth factors released spontaneously in inflammatory arthritis as platelet derived growth factor and tumour necrosis factor‐alpha', Clinical Experimental Immunology, 86, pp. 79 - 86, http://dx.doi.org/10.1111/j.1365-2249.1991.tb05777.x

Por SB; Cooley MA; Breit SN; Penny R; French PW, 1991, 'Antibodies to tubulin and actin bind to the surface of a human monocytic cell line, U937.', Journal of Histochemistry & Cytochemistry, 39, pp. 981 - 985, http://dx.doi.org/10.1177/39.7.1865114

Gibson PG; Breit SN; Bryant DH, 1990, 'Hypoxia during bronchoalveolar lavage', Australian and New Zealand Journal of Medicine, 20, pp. 39 - 43, http://dx.doi.org/10.1111/j.1445-5994.1990.tb00368.x

Thornton SC; Por SB; Walsh BJ; Penny R; Breit SN, 1990, 'Interaction of immune and connective tissue cells: I. The effect of lymphokines and monokines on fibroblast growth.', J Leukoc Biol, 47, pp. 312 - 320, http://dx.doi.org/10.1002/jlb.47.4.312

Lloyd AR; Breit SN; Rozenberg MC, 1989, 'Recurrent fever in Sjøgren's syndrome.', Med J Aust, 151, pp. 163 - 167, https://www.ncbi.nlm.nih.gov/pubmed/2755376

Hicks C; Breit SN; Penny. R, 1989, 'Response of microvascular endothelial cells to biological response modifiers', Immunology & Cell Biology, 67, pp. 271 - 277, http://dx.doi.org/10.1038/icb.1989.41

Breit SN; Cairns D; Szentirmay A; Callaghan T; Murray D; Wacher T; Gibson PG; Marks G; Bryant DH; Yeates M, 1989, 'The presence of Sjögren's syndrome is a major determinant of the pattern of interstitial lung disease in scleroderma and other connective tissue diseases.', J Rheumatol, 16, pp. 1043 - 1049, https://www.ncbi.nlm.nih.gov/pubmed/2585401

Gibson PG; Robinson BW; McLennan G; Bryant DH; Breit SN, 1989, 'The role of bronchoalveolar lavage in the assessment of diffuse lung diseases.', Aust N Z J Med, 19, pp. 281 - 291, http://dx.doi.org/10.1111/j.1445-5994.1989.tb00263.x

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