By Dr Anbu Thalamuthu

Journal articles

Lipnicki DM; Crawford JD; Dutta R; Thalamuthu A; Kochan NA; Andrews G; Lima-Costa MF; Castro-Costa E; Brayne C; Matthews FE; Stephan BCM; Lipton RB; Katz MJ; Ritchie K; Scali J; Ancelin ML; Scarmeas N; Yannakoulia M; Dardiotis E; Lam LCW; Wong CHY; Fung AWT; Guaita A; Vaccaro R; Davin A; Kim KW; Han JW; Kim TH; Anstey KJ; Cherbuin N; Butterworth P; Scazufca M; Kumagai S; Chen S; Narazaki K; Ng TP; Gao Q; Reppermund S; Brodaty H; Lobo A; Lopez-Anton R; Santabárbara J; Sachdev PS, 2017, 'Age-related cognitive decline and associations with sex, education and apolipoprotein E genotype across ethnocultural groups and geographic regions: a collaborative cohort study', PLoS Medicine, 14, pp. e1002261, http://dx.doi.org/10.1371/journal.pmed.1002261

Hibar DP; Adams HHH; Jahanshad N; Chauhan G; Stein JL; Hofer E; Renteria ME; Bis JC; Arias-Vasquez A; Ikram MK; Desrivières S; Vernooij MW; Abramovic L; Alhusaini S; Amin N; Andersson M; Arfanakis K; Aribisala BS; Armstrong NJ; Athanasiu L; Axelsson T; Beecham AH; Beiser A; Bernard M; Blanton SH; Bohlken MM; Boks MP; Bralten J; Brickman AM; Carmichael O; Chakravarty MM; Chen Q; Ching CRK; Chouraki V; Cuellar-Partida G; Crivello F; Den Braber A; Doan NT; Ehrlich S; Giddaluru S; Goldman AL; Gottesman RF; Grimm O; Griswold ME; Guadalupe T; Gutman BA; Hass J; Haukvik UK; Hoehn D; Holmes AJ; Hoogman M; Janowitz D; Jia T; Jørgensen KN; Karbalai N; Kasperaviciute D; Kim S; Klein M; Kraemer B; Lee PH; Liewald DCM; Lopez LM; Luciano M; MacAre C; Marquand AF; Matarin M; Mather KA; Mattheisen M; McKay DR; Milaneschi Y; Muñoz Maniega S; Nho K; Nugent AC; Nyquist P; Loohuis LMO; Oosterlaan J; Papmeyer M; Pirpamer L; Pütz B; Ramasamy A; Richards JS; Risacher SL; Roiz-Santiañez R; Rommelse N; Ropele S; Rose EJ; Royle NA; Rundek T; Sämann PG; Saremi A; Satizabal CL; Schmaal L; Schork AJ; Shen L; Shin J; Shumskaya E; Smith AV; Sprooten E; Strike LT; Teumer A; Brodaty H; Sachdev P; Schofield P; Wen W; Kwok J; Reppermund S; Assareh A; Thalamuthu A, 2017, 'Novel genetic loci associated with hippocampal volume', Nature Communications, 8, pp. 13624, http://dx.doi.org/10.1038/ncomms13624

Tsang R; Reppermund S; Thalamuthu A; Ames D; Wright M; Trollor J; Sachdev P; Mather K, 2017, 'Modelling genetic and environmental influences on depressive symptoms and their covariation with anxiety and vascular phenotypes: findings from the Older Australian Twins Study', Frontiers in Psychiatry, 8, http://dx.doi.org/10.3389/conf.fpsyt.2017.48.00014

Perry A; Wen W; Kochan NA; Thalamuthu A; Sachdev PS; Breakspear M, 2017, 'The independent influences of age and education on functional brain networks and cognition in healthy older adults', Human Brain Mapping, 38, pp. 5094 - 5114, http://dx.doi.org/10.1002/hbm.23717

Perry A; Wen W; Kochan N; Thalamuthu A; Sachdev P; Breakspear M, 2017, 'The independent influences of age and education on functional brain networks and cognition in healthy older adults', , http://dx.doi.org/10.1101/154898

Ciobanu LG; Sachdev PS; Trollor JN; Reppermund S; Thalamuthu A; Mather KA; Cohen-Woods S; Baune BT, 2016, 'Differential gene expression in brain and peripheral tissues in depression across the life span: A review of replicated findings', Neuroscience and Biobehavioral Reviews, 71, pp. 281 - 293, http://dx.doi.org/10.1016/j.neubiorev.2016.08.018

Adams HHH; Hibar DP; Chouraki V; Stein JL; Nyquist PA; Rentería ME; Trompet S; Arias-Vasquez A; Seshadri S; Desrivières S; Beecham AH; Jahanshad N; Wittfeld K; Van Der Lee SJ; Abramovic L; Alhusaini S; Amin N; Andersson M; Arfanakis K; Aribisala BS; Armstrong NJ; Athanasiu L; Axelsson T; Beiser A; Bernard M; Bis JC; Blanken LME; Blanton SH; Bohlken MM; Boks MP; Bralten J; Brickman AM; Carmichael O; Chakravarty MM; Chauhan G; Chen Q; Ching CRK; Cuellar-Partida G; Braber AD; Doan NT; Ehrlich S; Filippi I; Ge T; Giddaluru S; Goldman AL; Gottesman RF; Greven CU; Grimm O; Griswold ME; Guadalupe T; Hass J; Haukvik UK; Hilal S; Hofer E; Hoehn D; Holmes AJ; Hoogman M; Janowitz D; Jia T; Kasperaviciute D; Kim S; Klein M; Kraemer B; Lee PH; Liao J; Liewald DCM; Lopez LM; Luciano M; Macare C; Marquand A; Matarin M; Mather KA; Mattheisen M; Mazoyer B; McKay DR; McWhirter R; Milaneschi Y; Mirza-Schreiber N; Muetzel RL; Maniega SM; Nho K; Nugent AC; Loohuis LMO; Oosterlaan J; Papmeyer M; Pappa I; Pirpamer L; Pudas S; Pütz B; Rajan KB; Ramasamy A; Richards JS; Risacher SL; Roiz-Santiañez R; Rommelse N; Rose EJ; Royle NA; Rundek T; Sämann PG; Satizabal CL, 2016, 'Novel genetic loci underlying human intracranial volume identified through genome-wide association', Nature Neuroscience, 19, pp. 1569 - 1582, http://dx.doi.org/10.1038/nn.4398

Mather KA; Armstrong NJ; Thalamuthu A; Kwok JBJ, 2016, 'Tick tock: DNA methylation, the epigenetic clock and exceptional longevity', Epigenomics, 8, pp. 1577 - 1582, http://dx.doi.org/10.2217/epi-2016-0137

Wen W; Thalamuthu A; Mather KA; Zhu W; Jiang J; De Micheaux PL; Wright MJ; Ames D; Sachdev PS, 2016, 'Distinct Genetic Influences on Cortical and Subcortical Brain Structures', Scientific Reports, 6, pp. 32760 - 32760, http://dx.doi.org/10.1038/srep32760

Muenchhoff J; Poljak A; Thalamuthu A; Gupta VB; Chatterjee P; Raftery M; Masters CL; Morris JC; Bateman RJ; Fagan AM; Martins RN; Sachdev PS, 2016, 'Changes in the plasma proteome at asymptomatic and symptomatic stages of autosomal dominant Alzheimer's disease', Scientific Reports, 6, pp. 29078 - 29078, http://dx.doi.org/10.1038/srep29078

Sachdev PS; Thalamuthu A; Mather KA; Ames D; Wright MJ; Wen W; Bowden J; Lee T; Brodaty H; Crawford J; Duckworth T; Kang K; Garden N; Martin N; Lemmon C; Schofield P, 2016, 'White Matter Hyperintensities Are under Strong Genetic Influence', Stroke, 47, pp. 1422 - 1428, http://dx.doi.org/10.1161/STROKEAHA.116.012532

Lupton MK; Strike L; Hansell NK; Wen W; Mather KA; Armstrong NJ; Thalamuthu A; McMahon KL; de Zubicaray GI; Assareh AA; Simmons A; Proitsi P; Powell JF; Montgomery GW; Hibar DP; Westman E; Tsolaki M; Kloszewska I; Soininen H; Mecocci P; Velas B; Lovestone S; Brodaty H; Ames D; Trollor JN; Martin NG; Thompson PM; Sachdev PS; Wright MJ, 2016, 'The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume', Neurobiology of Aging, 40, pp. 68 - 77, http://dx.doi.org/10.1016/j.neurobiolaging.2015.12.023

Mather KA; Thalamuthu A; Oldmeadow C; Song F; Armstrong NJ; Poljak A; Holliday EG; McEvoy M; Kwok JB; Assareh AA; Reppermund S; Kochan NA; Lee T; Ames D; Wright MJ; Trollor JN; Schofield PW; Brodaty H; Scott RJ; Schofield PR; Attia JR; Sachdev PS; Schofield P, 2016, 'Genome-wide significant results identified for plasma apolipoprotein H levels in middle-aged and older adults', Scientific Reports, 6, pp. 23675, http://dx.doi.org/10.1038/srep23675

Mohan A; Mather KA; Thalamuthu A; Baune BT; Sachdev PS, 2016, 'Gene expression in the aging human brain: An overview', Current Opinion in Psychiatry, 29, pp. 159 - 167, http://dx.doi.org/10.1097/YCO.0000000000000238

Franke B; van Hulzen KJE; Arias-Vasquez A; Bralten J; Hoogman M; Klein M; van Donkelaar MMJ; Hakobjan MMH; Heister AJGAM; Makkinje RRR; Naber MAM; van der Marel SSL; Mostert JC; Brunner HG; van Bokhoven H; Zwiers MP; Buitelaar JK; Fernández G; Fisher SE; Francks C; Stein JL; Hibar DP; Thompson PM; Ripke S; Anttila V; Neale BM; Farh KH; Bulik-Sullivan B; Huang H; Fromer M; Goldstein JI; Daly MJ; Walters RK; Smoller JW; Lee P; Belliveau RA; Bergen SE; Bevilacqua E; Chambert KD; Genovese G; O'Dushlaine C; Scolnick EM; McCarroll SA; Moran JL; Palotie A; Petryshen TL; Erk S; Heinz A; Mohnke S; Romanczuk-Seiferth N; Walter H; DeLisi LE; McCarley RW; Mesholam-Gately RI; Seidman LJ; Nichols TE; Neale MC; McIntosh AM; Papmeyer M; Sprooten E; Lawrie SM; Sussmann JE; McMahon FJ; Yao Y; Meyer-Lindenberg A; Schwarz E; Grimm O; Mattheisen M; Agerbo E; Demontis D; Hansen T; Mors O; Olsen L; Rasmussen HB; Børglum AD; Mortensen PB; Werge T; Andreassen OA; Brown AA; Athanasiu L; Hartberg CB; Haukvik U; Melle I; Gruber O; Kraemer B; Keil M; Sachdev PS; Mather KA; Thalamuthu A; Armstrong NJ; Assareh AA; Brodaty H; Reppermund S; Wen W; Roiz-Santiañez R; Perez-Iglesias R; Saykin AJ; Kim S; Nho K; Risacher SL; Schofield P; Carr V; Kwok J; Schofield P, 2016, 'Genetic influences on schizophrenia and subcortical brain volumes: Large-scale proof of concept', Nature Neuroscience, 19, pp. 420 - 431, http://dx.doi.org/10.1038/nn.4228

Lazarus J; Mather KA; Thalamuthu A; Kwok JB, 2015, 'Genetic factors and epigenetic mechanisms of longevity: Current perspectives', Epigenomics, 7, pp. 1339 - 1349, http://dx.doi.org/10.2217/epi.15.80

Sachdev PS; Lipnicki DM; Kochan NA; Crawford JD; Thalamuthu A; Andrews G; Brayne C; Matthews FE; Stephan BCM; Lipton RB; Katz MJ; Ritchie K; Carrière I; Ancelin ML; Lam LCW; Wong CHY; Fung AWT; Guaita A; Vaccaro R; Davin A; Ganguli M; Dodge H; Hughes T; Anstey KJ; Cherbuin N; Butterworth P; Ng TP; Gao Q; Reppermund S; Brodaty H; Schupf N; Manly J; Stern Y; Lobo A; Lopez-Anton R; Santabárbara J; Zimmerman M; Derby C; Leung GTY; Chan WC; Polito L; Abbondanza S; Valle E; Colombo M; Vitali SF; Fossi S; Zaccaria D; Forloni G; Villani S; Christensen H; MacKinnon A; Easteal S; Jacomb T; Maxwell K; Bowman A; Burns K; Broe A; Dekker J; Dooley L; De Permentier M; Fairjones S; Fletcher J; French T; Foster C; Nugent-Cleary-Fox E; Gooi C; Harvey E; Helyer R; Hsieh S; Hughes L; Jacek S; Johnston M; McCade D; Meeth S; Milne E; Moir A; O'Grady R; Pfaeffli K; Pose C; Reuser L; Rose A; Schofield P; Shahnawaz Z; Sharpley A; Thompson C; Queisser W; Wong S; Mayeux R; Brickman A; Luchsinger J; Sanchez D; Tang MX; Andrews H; Marcos G; De-La-Cámara C; Saz P; Ventura T; Quintanilla MA; Lobo E; Schofield P, 2015, 'The prevalence of mild cognitive impairment in diverse geographical and ethnocultural regions: The COSMIC Collaboration', PLoS ONE, 10, pp. e0142388, http://dx.doi.org/10.1371/journal.pone.0142388

Boraxbekk CJ; Ames D; Kochan NA; Lee T; Thalamuthu A; Wen W; Armstrong NJ; Kwok JBJ; Schofield PR; Reppermund S; Wright MJ; Trollor JN; Brodaty H; Sachdev P; Mather KA; Schofield P, 2015, 'Investigating the influence of KIBRA and CLSTN2 genetic polymorphisms on cross-sectional and longitudinal measures of memory performance and hippocampal volume in older individuals', Neuropsychologia, 78, pp. 10 - 17, http://dx.doi.org/10.1016/j.neuropsychologia.2015.09.031

Jiang J; Trollor JN; Brown DA; Crawford JD; Thalamuthu A; Smith E; Breit SN; Liu T; Brodaty H; Baune BT; Sachdev PS; Wen W, 2015, 'An inverse relationship between serum macrophage inhibitory cytokine-1 levels and brain white matter integrity incommunity-dwelling older individuals', Psychoneuroendocrinology, 62, pp. 80 - 88, http://dx.doi.org/10.1016/j.psyneuen.2015.07.610

Perry A; Wen W; Lord A; Thalamuthu A; Roberts G; Mitchell PB; Sachdev PS; Breakspear M, 2015, 'The organisation of the elderly connectome', NeuroImage, 114, pp. 414 - 426, http://dx.doi.org/10.1016/j.neuroimage.2015.04.009

Jiang J; Wen W; Brown DA; Crawford J; Thalamuthu A; Smith E; Breit SN; Liu T; Zhu W; Brodaty H; Baune BT; Trollor JN; Sachdev PS, 2015, 'The relationship of serum macrophage inhibitory cytokine - 1 levels with gray matter volumes in community-dwelling older individuals', PLoS ONE, 10, pp. e0123399, http://dx.doi.org/10.1371/journal.pone.0123399

Hibar DP; Stein JL; Renteria ME; Arias-Vasquez A; Desrivières S; Jahanshad N; Toro R; Wittfeld K; Abramovic L; Andersson M; Aribisala BS; Armstrong NJ; Bernard M; Bohlken MM; Boks MP; Bralten J; Brown AA; Mallar Chakravarty M; Chen Q; Ching CRK; Cuellar-Partida G; Den Braber A; Giddaluru S; Goldman AL; Grimm O; Guadalupe T; Hass J; Woldehawariat G; Holmes AJ; Hoogman M; Janowitz D; Jia T; Kim S; Klein M; Kraemer B; Lee PH; Olde Loohuis LM; Luciano M; MacAre C; Mather KA; Mattheisen M; Milaneschi Y; Nho K; Papmeyer M; Ramasamy A; Risacher SL; Roiz-Santiañez R; Rose EJ; Salami A; Sämann PG; Schmaal L; Schork AJ; Shin J; Strike LT; Teumer A; Van Donkelaar MMJ; Van Eijk KR; Walters RK; Westlye LT; Whelan CD; Winkler AM; Zwiers MP; Alhusaini S; Athanasiu L; Ehrlich S; Hakobjan MMH; Hartberg CB; Haukvik UK; Heister AJGAM; Hoehn D; Kasperaviciute D; Liewald DCM; Lopez LM; Makkinje RRR; Matarin M; Naber MAM; Reese McKay D; Needham M; Nugent AC; Pütz B; Royle NA; Shen L; Sprooten E; Trabzuni D; Van Der Marel SSL; Van Hulzen KJE; Walton E; Wolf C; Almasy L; Ames D; Arepalli S; Assareh AA; Bastin ME; Brodaty H; Bulayeva KB; Carless MA; Cichon S; Corvin A; Curran JE; Czisch M; Schofield P; Sachdev P; Wen W; Kwok J; Thalamuthu A; Reppermund S; Schofield P, 2015, 'Common genetic variants influence human subcortical brain structures', Nature, 520, pp. 224 - 229, http://dx.doi.org/10.1038/nature14101

Davies G; Armstrong N; Bis JC; Bressler J; Chouraki V; Giddaluru S; Hofer E; Ibrahim-Verbaas CA; Kirin M; Lahti J; Van Der Lee SJ; Le Hellard S; Liu T; Marioni RE; Oldmeadow C; Postmus I; Smith AV; Smith JA; Thalamuthu A; Thomson R; Vitart V; Wang J; Yu L; Zgaga L; Zhao W; Boxall R; Harris SE; Hill WD; Liewald DC; Luciano M; Adams H; Ames D; Amin N; Amouyel P; Assareh AA; Au R; Becker JT; Beiser A; Berr C; Bertram L; Boerwinkle E; Buckley BM; Campbell H; Corley J; De Jager PL; Dufouil C; Eriksson JG; Espeseth T; Faul JD; Ford I; Scotland G; Gottesman RF; Griswold ME; Gudnason V; Harris TB; Heiss G; Hofman A; Holliday EG; Huffman J; Kardia SLR; Kochan N; Knopman DS; Kwok JB; Lambert JC; Lee T; Li G; Li SC; Loitfelder M; Lopez OL; Lundervold AJ; Lundqvist A; Mather KA; Mirza SS; Nyberg L; Oostra BA; Palotie A; Papenberg G; Pattie A; Petrovic K; Polasek O; Psaty BM; Redmond P; Reppermund S; Rotter JI; Schmidt H; Schuur M; Schofield PW; Scott RJ; Steen VM; Stott DJ; Van Swieten JC; Taylor KD; Trollor J; Trompet S; Uitterlinden AG; Weinstein G; Widen E; Windham BG; Jukema JW; Wright AF; Sachdev P; Schofield P; Brodaty H; Schofield P, 2015, 'Genetic contributions to variation in general cognitive function: A meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)', Molecular Psychiatry, 20, pp. 183 - 192, http://dx.doi.org/10.1038/mp.2014.188

Chan JPL; Thalamuthu A; Oldmeadow C; Armstrong NJ; Holliday EG; McEvoy M; Kwok JB; Assareh AA; Peel R; Hancock SJ; Reppermund S; Menant J; Trollor JN; Brodaty H; Schofield PR; Attia JR; Sachdev PS; Scott RJ; Mather KA; Schofield P, 2015, 'Genetics of hand grip strength in mid to late life', Age (Dordrecht, Netherlands), 37, pp. 9745 - 9745, http://dx.doi.org/10.1007/s11357-015-9745-5

Mather KA; Armstrong NJ; Wen W; Kwok JB; Assareh AA; Thalamuthu A; Reppermund S; Duesing K; Wright MJ; Ames D; Trollor JN; Brodaty H; Schofield PR; Sachdev PS; Schofield P, 2015, 'Investigating the genetics of hippocampal volume in older adults without dementia', PLoS ONE, 10, pp. e0116920, http://dx.doi.org/10.1371/journal.pone.0116920

Wu HZY; Ong KL; Seeher K; Armstrong NJ; Thalamuthu A; Brodaty H; Sachdev P; Mather K, 2015, 'Circulating microRNAs as biomarkers of alzheimer's disease: A systematic review', Journal of Alzheimer's Disease, 49, pp. 755 - 766, http://dx.doi.org/10.3233/JAD-150619

Lazarus J; Mather KA; Armstrong NJ; Song F; Poljak A; Thalamuthu A; Lee T; Kochan NA; Brodaty H; Wright MJ; Ames D; Sachdev PS; Kwok JBJ, 2015, 'DNA methylation in the apolipoprotein-A1 gene is associated with episodic memory performance in healthy older individuals', Journal of Alzheimer's Disease, 44, pp. 175 - 182, http://dx.doi.org/10.3233/JAD-141314

Kanchibhotla SC; Mather KA; Thalamuthu A; Zhuang L; Schofield PR; Kwok JBJ; Ames D; Wright MJ; Trollor JN; Wen W; Sachdev PS; Schofield P, 2014, 'Genetics of microstructure of the corpus callosum in older adults', PLoS ONE, 9, pp. e113181, http://dx.doi.org/10.1371/journal.pone.0113181

Zakharov S; Teoh GHK; Salim A; Thalamuthu A, 2014, 'A method to incorporate prior information into score test for genetic association studies', BMC Bioinformatics, 15, http://dx.doi.org/10.1186/1471-2105-15-24

Thompson PM; Stein JL; Medland SE; Hibar DP; Vasquez AA; Renteria ME; Toro R; Jahanshad N; Schumann G; Franke B; Wright MJ; Martin NG; Agartz I; Alda M; Alhusaini S; Almasy L; Almeida J; Alpert K; Andreasen NC; Andreassen OA; Apostolova LG; Appel K; Armstrong NJ; Aribisala B; Bastin ME; Bauer M; Bearden CE; Bergmann Ø; Binder EB; Blangero J; Bockholt HJ; Bøen E; Bois C; Boomsma DI; Booth T; Bowman IJ; Bralten J; Brouwer RM; Brunner HG; Brohawn DG; Buckner RL; Buitelaar J; Bulayeva K; Bustillo JR; Calhoun VD; Cannon DM; Cantor RM; Carless MA; Caseras X; Cavalleri GL; Chakravarty MM; Chang KD; Ching CRK; Christoforou A; Cichon S; Clark VP; Conrod P; Coppola G; Crespo-Facorro B; Curran JE; Czisch M; Deary IJ; de Geus EJC; den Braber A; Delvecchio G; Depondt C; de Haan L; de Zubicaray GI; Dima D; Dimitrova R; Djurovic S; Dong H; Donohoe G; Duggirala R; Dyer TD; Ehrlich S; Ekman CJ; Elvsåshagen T; Emsell L; Erk S; Espeseth T; Fagerness J; Fears S; Fedko I; Fernández G; Fisher SE; Foroud T; Fox PT; Francks C; Frangou S; Frey EM; Frodl T; Frouin V; Garavan H; Giddaluru S; Glahn DC; Godlewska B; Goldstein RZ; Gollub RL; Grabe HJ, 2014, 'The ENIGMA Consortium: Large-scale collaborative analyses of neuroimaging and genetic data', Brain Imaging and Behavior, 8, pp. 153 - 182, http://dx.doi.org/10.1007/s11682-013-9269-5

Sachdev PS; Lee T; Wen W; Ames D; Batouli AH; Bowden J; Brodaty H; Chong E; Crawford J; Kang K; Mather K; Lammel A; Slavin MJ; Thalamuthu A; Trollor J; Wright MJ; OATS Research Team ; Kumfor F; Kwok J; Menant J, 2013, 'The contribution of twins to the study of cognitive ageing and dementia: The Older Australian Twins Study', International Review of Psychiatry, 25, pp. 738 - 747, http://dx.doi.org/10.3109/09540261.2013.870137

Zakharov S; Wong TY; Aung T; Vithana EN; Khor CC; Salim A; Thalamuthu A, 2013, 'Combined genotype and haplotype tests for region-based association studies', BMC Genomics, 14, http://dx.doi.org/10.1186/1471-2164-14-569

Duskova K; Nagilla P; Le HS; Iyer P; Thalamuthu A; Martinson J; Bar-Joseph Z; Buchanan W; Rinaldo C; Ayyavoo V, 2013, 'MicroRNA regulation and its effects on cellular transcriptome in Human Immunodeficiency Virus-1 (HIV-1) infected individuals with distinct viral load and CD4 cell counts', BMC Infectious Diseases, 13, http://dx.doi.org/10.1186/1471-2334-13-250

Zakharov S; Salim A; Thalamuthu A, 2013, 'Comparison of similarity-based tests and pooling strategies for rare variants', BMC Genomics, 14, http://dx.doi.org/10.1186/1471-2164-14-50

Sandhu KS; Li G; Poh HM; Quek YLK; Sia YY; Peh SQ; Mulawadi FH; Lim J; Sikic M; Menghi F; Thalamuthu A; Sung WK; Ruan X; Fullwood MJ; Liu E; Csermely P; Ruan Y, 2012, 'Large-Scale Functional Organization of Long-Range Chromatin Interaction Networks', Cell Reports, 2, pp. 1207 - 1219, http://dx.doi.org/10.1016/j.celrep.2012.09.022

Ng KP; Hillmer AM; Chuah CTH; Juan WC; Ko TK; Teo ASM; Ariyaratne PN; Takahashi N; Sawada K; Fei Y; Soh S; Lee WH; Huang JWJ; Allen JC; Woo XY; Nagarajan N; Kumar V; Thalamuthu A; Poh WT; Ang AL; Mya HT; How GF; Yang LY; Koh LP; Chowbay B; Chang CT; Nadarajan VS; Chng WJ; Than H; Lim LC; Goh YT; Zhang S; Poh D; Tan P; Seet JE; Ang MK; Chau NM; Ng QS; Tan DSW; Soda M; Isobe K; Nöthen MM; Wong TY; Shahab A; Ruan X; Cacheux-Rataboul V; Sung WK; Tan EH; Yatabe Y; Mano H; Soo RA; Chin TM; Lim WT; Ruan Y; Ong ST, 2012, 'A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer', Nature Medicine, 18, pp. 521 - 528, http://dx.doi.org/10.1038/nm.2713

Thalamuthu A; Zhao J; Keong GTH; Kondragunta V; Mukhopadhyay I, 2011, 'Association tests for rare and common variants based on genotypic and phenotypic measures of similarity between individuals.', BMC Proc, 5 Suppl 9, pp. S89, http://dx.doi.org/10.1186/1753-6561-5-S9-S89

Zhao J; Thalamuthu A, 2011, 'Gene-based multiple trait analysis for exome sequencing data.', BMC Proc, 5 Suppl 9, pp. S75, http://dx.doi.org/10.1186/1753-6561-5-S9-S75

Liu T; Thalamuthu A, 2011, 'Identity by descent and association analysis of dichotomous traits based on large pedigrees.', BMC Proc, 5 Suppl 9, pp. S31, http://dx.doi.org/10.1186/1753-6561-5-S9-S31

Png E; Thalamuthu A; Ong RTH; Snippe H; Boland GJ; Seielstad M, 2011, 'A genome-wide association study of hepatitis B vaccine response in an Indonesian population reveals multiple independent risk variants in the HLA region', Human Molecular Genetics, 20, pp. 3893 - 3898, http://dx.doi.org/10.1093/hmg/ddr302

Low HQ; Chen CPLH; Kasiman K; Thalamuthu A; Ng SS; Foo JN; Chang HM; Wong MC; Tai ES; Liu J, 2011, 'A comprehensive association analysis of homocysteine metabolic pathway genes in singaporean Chinese with ischemic stroke', PLoS ONE, 6, http://dx.doi.org/10.1371/journal.pone.0024757

Gupta A; Nagilla P; Le HS; Bunney C; Zych C; Thalamuthu A; Bar-Joseph Z; Mathavan S; Ayyavoo V, 2011, 'Comparative expression profile of miRNA and mRNA In primary peripheral blood mononuclear cells infected with human immunodeficiency virus (HIV-1)', PLoS ONE, 6, http://dx.doi.org/10.1371/journal.pone.0022730

Liu T; Thalamuthu A; Liu JJ; Chen C; Wang Z; Wu R, 2011, 'Asymptotic distribution for epistatic tests in case-control studies', Genomics, 98, pp. 145 - 151, http://dx.doi.org/10.1016/j.ygeno.2011.05.001

Thalamuthu A; Khor CC; Venkataraman D; Koh LW; Tan DTH; Aung T; Mehta JS; Vithana EN, 2011, 'Association of TCF4 gene polymorphisms with Fuchs' corneal dystrophy in the Chinese', Investigative Ophthalmology and Visual Science, 52, pp. 5573 - 5578, http://dx.doi.org/10.1167/iovs.11-7568

Teo SM; Pawitan Y; Kumar V; Thalamuthu A; Seielstad M; Chia KS; Salim A, 2011, 'Multi-platform segmentation for joint detection of copy number variants', Bioinformatics, 27, pp. 1555 - 1561, http://dx.doi.org/10.1093/bioinformatics/btr162

Li J; Humphreys K; Heikkinen T; Aittomäki K; Blomqvist C; Pharoah PDP; Dunning AM; Ahmed S; Hooning MJ; Martens JWM; Van Den Ouweland AMW; Alfredsson L; Palotie A; Peltonen-Palotie L; Irwanto A; Low HQ; Teoh GHK; Thalamuthu A; Easton DF; Nevanlinna H; Liu J; Czene K; Hall P, 2011, 'A combined analysis of genome-wide association studies in breast cancer', Breast Cancer Research and Treatment, 126, pp. 717 - 727, http://dx.doi.org/10.1007/s10549-010-1172-9

Sng CCA; Cackett PD; Yeo IY; Thalamuthu A; Venkatraman A; Venkataraman D; Koh AH; Tai ES; Wong TY; Aung T; Vithana EN, 2011, 'Toll-like receptor 3 polymorphism rs3775291 is not associated with choroidal neovascularization or polypoidal choroidal vasculopathy in Chinese subjects', Ophthalmic Research, 45, pp. 191 - 196, http://dx.doi.org/10.1159/000321387

Amerasinghe N; Zhang J; Thalamuthu A; He M; Vithana EN; Viswanathan A; Wong TY; Foster PJ; Aung T, 2011, 'The heritability and sibling risk of angle closure in Asians', Ophthalmology, 118, pp. 480 - 485, http://dx.doi.org/10.1016/j.ophtha.2010.06.043

Zhao J; Gupta S; Seielstad M; Liu J; Thalamuthu A, 2011, 'Pathway-based analysis using reduced gene subsets in genome-wide association studies', BMC Bioinformatics, 12, http://dx.doi.org/10.1186/1471-2105-12-17

Chan SL; Thalamuthu A; Goh BC; Chia KS; Chuah B; Wong A; Lee SC, 2011, 'Exon sequencing and association analysis of EPHX1 genetic variants with maintenance warfarin dose in a multiethnic Asian population', Pharmacogenetics and Genomics, 21, pp. 35 - 41, http://dx.doi.org/10.1097/FPC.0b013e328341b68f

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