By Dr Ashleigh Evans

Journal articles

Afrose D; Alfonso-Sánchez S; Philp A; Hansbro PM; Su QP; McClements L, 2026, 'Targeting trophoblast cell mitochondrial dysfunction in preeclampsia via drug repurposing', Chemico Biological Interactions, 424, http://dx.doi.org/10.1016/j.cbi.2025.111883

Tahmasbpour E; Philp A; Sivasubramaniam V; Thomson C; Plit M; Ravipati A; Raftery M; Darley D, 2025, 'Proteomic Analysis of Transbronchial Biopsies to Discover Novel Biomarkers for Early Identification of Chronic Lung Allograft Dysfunction', Transplantation Direct, 11, pp. e1800, http://dx.doi.org/10.1097/TXD.0000000000001800

Liu G; Hsu AC; Geirnaert S; Cong C; Nair PM; Shen S; Marshall JE; Haw TJ; Fricker M; Philp AM; Hansbro NG; Pavlidis S; Guo Y; Burgess JK; Castellano L; Ieni A; Caramori G; Oliver BGG; Chung KF; Adcock IM; Knight DA; Polverino F; Bracke K; Wark PA; Hansbro PM, 2025, 'Vitronectin regulates lung tissue remodeling and emphysema in chronic obstructive pulmonary disease', Molecular Therapy, 33, pp. 917 - 932, http://dx.doi.org/10.1016/j.ymthe.2025.01.032

Tahmasbpour E; Philp A; Cree T; Sivasubramaniam V; Thomson C; Plit M; Ravipati A; Raftery M; Darley DR, 2025, 'Proteomic Analysis of Transbronchial Biopsy Tissue Reveals a Distinct Proteome and Mechanistic Pathways in High-Grade Eosinophilic Inflammation After Lung Transplantation', Transplant International, 38, http://dx.doi.org/10.3389/ti.2025.14080

Filipe EC; Velayuthar S; Philp A; Nobis M; Latham SL; Parker AL; Murphy KJ; Wyllie K; Major GS; Contreras O; Mok ETY; Enriquez RF; McGowan S; Feher K; Quek LE; Hancock SE; Yam M; Tran E; Setargew YFI; Skhinas JN; Chitty JL; Phimmachanh M; Han JZR; Cadell AL; Papanicolaou M; Mahmodi H; Kiedik B; Junankar S; Ross SE; Lam N; Coulson R; Yang J; Zaratzian A; Da Silva AM; Tayao M; Chin IL; Cazet A; Kansara M; Segara D; Parker A; Hoy AJ; Harvey RP; Bogdanovic O; Timpson P; Croucher DR; Lim E; Swarbrick A; Holst J; Turner N; Choi YS; Kabakova IV; Philp A; Cox TR, 2024, 'Tumor Biomechanics Alters Metastatic Dissemination of Triple Negative Breast Cancer via Rewiring Fatty Acid Metabolism', Advanced Science, 11, http://dx.doi.org/10.1002/advs.202307963

Koay YC; Liu RP; McIntosh B; Vigder N; Lauren S; Bai AY; Tomita S; Li D; Harney D; Hunter B; Zhang Y; Yang J; Bannon P; Philp A; Philp A; Kaye DM; Larance M; Lal S; O'Sullivan JF, 2024, 'The Efficacy of Risk Factor Modification Compared to NAD+ Repletion in Diastolic Heart Failure', Jacc Basic to Translational Science, 9, pp. 733 - 750, http://dx.doi.org/10.1016/j.jacbts.2024.01.011

Beretta M; Dai Y; Olzomer EM; Vancuylenburg CS; Santiago-Rivera JA; Philp AM; Hargett SR; Li K; Shah DP; Chen SY; Alexopoulos SJ; Li C; Harris TE; Lee B; Wathier M; Cermak JM; Tucker SP; Turner N; Bayliss DA; Philp A; Byrne FL; Santos WL; Hoehn KL, 2024, 'Liver-Selective Imidazolopyrazine Mitochondrial Uncoupler SHD865 Reverses Adiposity and Glucose Intolerance in Mice', Diabetes, 73, pp. 374 - 384, http://dx.doi.org/10.2337/db23-0233

Liu G; Haw TJ; Starkey MR; Philp AM; Pavlidis S; Nalkurthi C; Nair PM; Gomez HM; Hanish I; Hsu AC; Hortle E; Pickles S; Rojas-Quintero J; Estepar RSJ; Marshall JE; Kim RY; Collison AM; Mattes J; Idrees S; Faiz A; Hansbro NG; Fukui R; Murakami Y; Cheng HS; Tan NS; Chotirmall SH; Horvat JC; Foster PS; Oliver BG; Polverino F; Ieni A; Monaco F; Caramori G; Sohal SS; Bracke KR; Wark PA; Adcock IM; Miyake K; Sin DD; Hansbro PM, 2023, 'TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase', Nature Communications, 14, http://dx.doi.org/10.1038/s41467-023-42913-z

Padilha C; Philp AM, 2023, 'A Perspective on "Hypoxia Resistance is an Inherent Phenotype of the Mouse Flexor Digitorum Brevis Skeletal Muscle"', Function, 4, http://dx.doi.org/10.1093/function/zqad024

Woodhouse RM; Frolows N; Wang G; Hawdon A; Wong EHK; Dansereau LC; Su Y; Adair LD; New EJ; Philp AM; Tan WK; Philp A; Ashe A, 2022, 'Mitochondrial succinate dehydrogenase function is essential for sperm motility and male fertility', Iscience, 25, http://dx.doi.org/10.1016/j.isci.2022.105573

Liu G; Jarnicki AG; Paudel KR; Lu W; Wadhwa R; Philp AM; Van Eeckhoutte H; Marshall JE; Malyla V; Katsifis A; Fricker M; Hansbro NG; Dua K; Kermani NZ; Eapen MS; Tiotiu A; Chung KF; Caramori G; Bracke K; Adcock IM; Sohal SS; Wark PA; Oliver BG; Hansbro PM, 2022, 'Adverse roles of mast cell chymase-1 in COPD', European Respiratory Journal, 60, http://dx.doi.org/10.1183/13993003.01431-2021

Sligar J; DeBruin DA; Saner NJ; Philp AM; Philp A, 2022, 'The importance of mitochondrial quality control for maintaining skeletal muscle function across health span', American Journal of Physiology Cell Physiology, 322, pp. C461 - C467, http://dx.doi.org/10.1152/ajpcell.00388.2021

Liu G; Philp AM; Corte T; Travis MA; Schilter H; Hansbro NG; Burns CJ; Eapen MS; Sohal SS; Burgess JK; Hansbro PM, 2021, 'Therapeutic targets in lung tissue remodelling and fibrosis', Pharmacology and Therapeutics, 225, http://dx.doi.org/10.1016/j.pharmthera.2021.107839

Philp AM; Butterworth S; Davis ET; Jones SW, 2021, 'Enampt is localised to areas of cartilage damage in patients with hip osteoarthritis and promotes cartilage catabolism and inflammation', International Journal of Molecular Sciences, 22, http://dx.doi.org/10.3390/ijms22136719

Philp AM; Saner NJ; Lazarou M; Ganley IG; Philp A, 2021, 'The influence of aerobic exercise on mitochondrial quality control in skeletal muscle', Journal of Physiology, 599, pp. 3463 - 3476, http://dx.doi.org/10.1113/JP279411

Ellwood RA; Hewitt JE; Torregrossa R; Philp AM; Hardee JP; Hughes S; van de Klashorst D; Gharahdaghi N; Anupom T; Slade L; Deane CS; Cooke M; Etheridge T; Piasecki M; Antebi A; Lynch GS; Philp A; Vanapalli SA; Whiteman M; Szewczyk NJ, 2021, 'Mitochondrial hydrogen sulfide supplementation improves health in the C. elegans Duchenne muscular dystrophy model', Proceedings of the National Academy of Sciences of the United States of America, 118, http://dx.doi.org/10.1073/pnas.2018342118

Hardee JP; Martins KJB; Miotto PM; Ryall JG; Gehrig SM; Reljic B; Naim T; Chung JD; Trieu J; Swiderski K; Philp AM; Watt MJ; Stroud DA; Koopman R; Steinberg GR; Lynch GS, 2021, 'Metabolic remodeling of dystrophic skeletal muscle reveals biological roles for dystrophin and utrophin in adaptation and plasticity', Molecular Metabolism, 45, http://dx.doi.org/10.1016/j.molmet.2020.101157

Stocks B; Ashcroft SP; Joanisse S; Dansereau LC; Koay YC; Elhassan YS; Lavery GG; Quek LE; O'Sullivan JF; Philp AM; Wallis GA; Philp A, 2021, 'Nicotinamide riboside supplementation does not alter whole-body or skeletal muscle metabolic responses to a single bout of endurance exercise', Journal of Physiology, 599, pp. 1513 - 1531, http://dx.doi.org/10.1113/JP280825

Ashcroft SP; Fletcher G; Philp AM; Jenkinson C; Das S; Hansbro PM; Atherton PJ; Philp A, 2021, 'Diet-induced Vitamin D deficiency reduces skeletal muscle mitochondrial respiration', Journal of Endocrinology, 249, pp. 113 - 124, http://dx.doi.org/10.1530/JOE-20-0233

Alexopoulos SJ; Chen SY; Brandon AE; Salamoun JM; Byrne FL; Garcia CJ; Beretta M; Olzomer EM; Shah DP; Philp AM; Hargett SR; Lawrence RT; Lee B; Sligar J; Carrive P; Tucker SP; Philp A; Lackner C; Turner N; Cooney GJ; Santos WL; Hoehn KL; Evans A, 2020, 'Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice', Nature Communications, 11, pp. 2397, http://dx.doi.org/10.1038/s41467-020-16298-2

Pearson MJ; Philp AM; Haq H; Cooke ME; Nicholson T; Grover LM; Newton Ede M; Jones SW, 2019, 'Evidence of Intrinsic Impairment of Osteoblast Phenotype at the Curve Apex in Girls With Adolescent Idiopathic Scoliosis', Spine Deformity, 7, pp. 533 - 542, http://dx.doi.org/10.1016/j.jspd.2018.11.016

Riquelme D; Silva I; Philp AM; Huidobro-Toro JP; Cerda O; Trimmer JS; Leiva-Salcedo E, 2018, 'Subcellular Localization and Activity of TRPM4 in Medial Prefrontal Cortex Layer 2/3', Frontiers in Cellular Neuroscience, 12, pp. 12, http://dx.doi.org/10.3389/fncel.2018.00012

Bishop HI; Cobb MM; Kirmiz M; Parajuli LK; Mandikian D; Philp AM; Melnik M; Kuja-Panula J; Rauvala H; Shigemoto R; Murray KD; Trimmer JS, 2018, 'Kv2 Ion Channels Determine the Expression and Localization of the Associated AMIGO-1 Cell Adhesion Molecule in Adult Brain Neurons', Frontiers in Molecular Neuroscience, 11, pp. 1, http://dx.doi.org/10.3389/fnmol.2018.00001

Pearson MJ; Herndler-Brandstetter D; Tariq MA; Nicholson TA; Philp AM; Smith HL; Davis ET; Jones SW; Lord JM, 2017, 'IL-6 secretion in osteoarthritis patients is mediated by chondrocyte-synovial fibroblast cross-talk and is enhanced by obesity', Scientific Reports, 7, http://dx.doi.org/10.1038/s41598-017-03759-w

Philp AM; Collier RL; Grover LM; Davis ET; Jones SW, 2017, 'Resistin promotes the abnormal Type I collagen phenotype of subchondral bone in obese patients with end stage hip osteoarthritis', Scientific Reports, 7, http://dx.doi.org/10.1038/s41598-017-04119-4

Philp AM; Davis ET; Jones SW, 2017, 'Developing anti-inflammatory therapeutics for patients with osteoarthritis', Rheumatology United Kingdom, 56, pp. 869 - 881, http://dx.doi.org/10.1093/rheumatology/kew278

Philp AM; Raja S; Philp A; Ede MPN; Jones SW, 2017, 'The effect of vancomycin and gentamicin antibiotics on human osteoblast proliferation, metabolic function, and bone mineralization', Spine, 42, pp. 202 - 207, http://dx.doi.org/10.1097/BRS.0000000000001712

Pearson MJ; Philp AM; Heward JA; Roux BT; Walsh DA; Davis ET; Lindsay MA; Jones SW, 2016, 'Long Intergenic Noncoding RNAs Mediate the Human Chondrocyte Inflammatory Response and Are Differentially Expressed in Osteoarthritis Cartilage', Arthritis and Rheumatology, 68, pp. 845 - 856, http://dx.doi.org/10.1002/art.39520

Ede MPN; Philp AM; Philp A; Richardson SM; Mohammad S; Jones SW, 2016, 'Povidone-iodine has a profound effect on in vitro osteoblast proliferation and metabolic function and inhibits their ability to mineralize and form bone', Spine, 41, pp. 729 - 734, http://dx.doi.org/10.1097/BRS.0000000000001332

Philp A; Belew MY; Evans A; Pham D; Sivia I; Chen A; Schenk S; Baar K, 2011, 'The PGC-1α-related coactivator promotes mitochondrial and myogenic adaptations in C2C12 myotubes', American Journal of Physiology Regulatory Integrative and Comparative Physiology, 301, pp. R864 - R872, http://dx.doi.org/10.1152/ajpregu.00232.2011

Stretton C; Evans A; Hundal HS, 2010, 'Cellular depletion of atypical PKCλ is associated with enhanced insulin sensitivity and glucose uptake in L6 rat skeletal muscle cells', AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 299, pp. E402 - E412, http://dx.doi.org/10.1152/ajpendo.00171.2010

Hawley SA; Ross FA; Chevtzoff C; Green KA; Evans A; Fogarty S; Towler MC; Brown LJ; Ogunbayo OA; Evans AM; Hardie DG, 2010, 'Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation', Cell Metabolism, 11, pp. 554 - 565, http://dx.doi.org/10.1016/j.cmet.2010.04.001

Conference Papers

Philp A; Pearson M; O'Leary M; Jones S, 2018, 'Association of chemerin levels in serum and synovial fluid with the severity of hip osteoarthritis', in Osteoarthritis and Cartilage, Elsevier, pp. s182, http://dx.doi.org/10.1016/j.joca.2018.02.391

Philp AM; Collier RL; Bartlett DB; Lord JM; Davis ET; Jones SW, 2016, 'EVIDENCE OF ABNORMAL TYPE I COLLAGEN COMPOSITION IN OBESE PATIENTS WITH OA', in OSTEOARTHRITIS AND CARTILAGE, ELSEVIER SCI LTD, NETHERLANDS, Amsterdam, pp. S388 - S389, presented at World Congress of the Osteoarthritis-Research-Society-International (OARSI) on Osteoarthritis, NETHERLANDS, Amsterdam, 31 March 2016 - 03 April 2016

Preprints

Alldritt I; Sligar J; Campelj D; Padilha CS; Ritenis E; Mantamadiotis T; Widodo S; Dinevska M; Nielsen J; Philp AM; Philp A, 2025, Exercise training improves sarcopenic muscle function via restoration of mitochondrial quality control, http://dx.doi.org/10.1101/2025.11.03.686168

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