By Dr Chai Ann Ng

Preprints

Lau CHY; Flood E; Hunter MJ; Williams-Noonan BJ; Corbett KM; Ng C-A; Bouwer JC; Stewart AG; Perozo E; Allen TW; Vandenberg JI, 2023, Potassium dependent structural changes in the selectivity filter of HERG potassium channels, , http://dx.doi.org/10.1101/2023.12.14.571769

Thomson K; Jiang C; Richardson E; Westphal D; Burkard T; Wolf C; Vatta M; Harrison S; Ingles J; Bezzina C; Kroncke B; Vandenberg J; Ng C-A, 2023, Clinical interpretation ofKCNH2variants using a robust PS3/BS3 functional patch clamp assay, , http://dx.doi.org/10.1101/2023.10.08.23296707

Copier JS; Bootsma M; Ng C; Wilde AAM; Bertels RA; Bikker H; Christiaans I; van der Crabben SN; Hol JA; Koopmann TT; Knijnenburg J; Lommerse AAJ; van der Smagt JJ; Bezzina CR; Vandenberg JI; Verkerk AO; Barge-Schaapveld DQCM; Lodder EM, 2022, Reclassification of a likely pathogenic Dutch founder variant in KCNH2; implications of reduced penetrance, , http://dx.doi.org/10.1101/2022.08.05.502917

Jiang C; Richardson E; Farr J; Hill A; Ullah R; Kroncke B; Harrison S; Thomson K; Ingles J; Vandenberg J; Ng C-A, 2021, A calibrated functional patch clamp assay to enhance clinical variant interpretation in KCNH2-related long QT syndrome, , http://dx.doi.org/10.1101/2021.12.13.472492

Vandenberg J; Lau C; Flood E; Hunter M; Ng C-A; Bouwer J; Stewart A; Perozo E; Allen T, 2021, Structural Basis for Rapid Voltage Dependent Inactivation of HERG Potassium Channels, , http://dx.doi.org/10.21203/rs.3.rs-1105661/v1

Li JV; Ng C-A; Cheng D; Yao M; Guo Y; Yu Z-Y; Ramaswamy Y; Ju LA; Kuchel PW; Feneley MP; Fatkin D; Cox CD, 2020, Modified N-linked glycosylation status predicts trafficking defective human Piezo1 channel mutations, , http://dx.doi.org/10.1101/2020.11.30.404962

Kozek KA; Glazer AM; Ng C-A; Blackwell D; Egly CL; Vanags LR; Blair M; Mitchell D; Matreyek KA; Fowler DM; Knollmann BC; Vandenberg J; Roden DM; Kroncke BM, 2020, High-throughput discovery of trafficking-deficient variants in the cardiac potassium channelKCNH2: Deep mutational scan ofKCNH2trafficking, , http://dx.doi.org/10.1101/2020.02.17.952606

Other

Ng CA; Kuchel PW; Vandenberg JI, 2012, Solution nmr structure of the S4S5 linker of herg potassium channel, Worldwide Protein Data Bank, , http://dx.doi.org/10.2210/pdb2le7/pdb

Ng CA; Hunter MJ; Mobli M; King GF; Kuchel PW; Vandenberg JI, 2011, Solution NMR structure of the N-terminal PAS domain of HERG potassium channel, Worldwide Protein Data Bank, , http://dx.doi.org/10.2210/pdb2l0w/pdb

Ng CA; Kato Y; Tanokura M; Brownlee RTC, 2007, Structure Characterisation of PINA WW Domain and Comparison with other Group IV WW Domains, PIN1 and ESS1, Worldwide Protein Data Bank, , http://dx.doi.org/10.2210/pdb2jv4/pdb

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