By Dr Charlotte Rose Lemech

Journal articles

Wynne CJ; Cole A; Lemech C; Wang G; Zhang Y; Chen B; Wang M; Li B; Xia M; Sinclair R, 2023, 'Safety, Pharmacokinetics and Preliminary Efficacy of IL4-Rα Monoclonal Antibody AK120 in Both Healthy and Atopic Dermatitis Subjects: A Phase I, Randomized, Two-Part, Double-Blind, Placebo-Controlled, Dose-Escalation, First-In-Human Clinical Study', Dermatology and Therapy, 13, pp. 2357 - 2373, http://dx.doi.org/10.1007/s13555-023-01010-1

Fries L; Formica N; Mallory RM; Zhou H; Plested JS; Kalkeri R; Moldovan I; Patel N; Albert G; Robinson M; Cho I; Chau G; Dubovsky F; Glenn GM; Adams M; Arya M; Athan E; Berger I; Bradley P; Glover R; Griffin P; Kim J; Kitchener S; Klein T; Leah A; Lemech C; Lickliter J; Manning MB; Napier-Flood F; Nugent P; Thackwray S; Turner M, 2023, 'Strong CD4+T-Cell Responses to Ancestral and Variant Spike Proteins Are Established by NVX-CoV2373 Severe Acute Respiratory Syndrome Coronavirus 2 Primary Vaccination', Journal of Infectious Diseases, 228, pp. 734 - 741, http://dx.doi.org/10.1093/infdis/jiad163

Lee DH; Han J-Y; Lemech CR; Millward M; Roohullah A; Choi JY; Park KE; Kim NY; Im S; Rajasekaran N; Lee S; Moon H; Hwang S; Shin Y; Lee S-H, 2023, 'ABN401 in patients with NSCLC with MET exon 14 (METex14) skipping: Result from the pilot expansion study.', Journal of Clinical Oncology, 41, pp. e21148 - e21148, http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e21148

Lemech C; Zhou C; Zhan X; Shi Y; Liu J; Piha-Paul SA; Richardson G; Qin G; Song PH; Shi L; Sun Y; Xia Y, 2023, 'Abstract CT178: GQ1001: A next generation HER2-targeting ADC that exhibits promising early clinical efficacy with excellent tolerance in a multi-center, Phase Ia study', Cancer Research, 83, pp. ct178 - ct178, http://dx.doi.org/10.1158/1538-7445.am2023-ct178

Lemech CR; Argent C; Scribner CL; Sharabi A; Daniels R; Appleman JR, 2023, 'Abstract CT180: Activation of innate and adaptive immune response with a clinical stage TLR7 agonist prodrug PRTX007', Cancer Research, 83, pp. CT180 - CT180, http://dx.doi.org/10.1158/1538-7445.am2023-ct180

Fu S; Falchook GS; Barve M; McKean M; Tan TJ; Lemech C; Chee CE; Marina N; Abbadessa G; Meng R; Rotolo F; Wang H; Deng J; Wang W; Wang R; Meniawy T, 2023, 'Abstract 2155: Joint modeling of safety and peripheral mode-of-action (MoA) biomarkers to support RP2D identification in Phase 1 study of SAR444245 (SAR’245) as monotherapy (mono) or combined with pembrolizumab (pembro) in patients with advanced solid tumors', Cancer Research, 83, pp. 2155 - 2155, http://dx.doi.org/10.1158/1538-7445.am2023-2155

Lemech CR; Kichenadasse G; Marschner JP; Alevizopoulos K; Otterlei M; Millward M, 2023, 'ATX-101, a cell-penetrating protein targeting PCNA, can be safely administered as intravenous infusion in patients and shows clinical activity in a Phase 1 study', Oncogene, 42, pp. 541 - 544, http://dx.doi.org/10.1038/s41388-022-02582-6

Lemech C; Dredge K; Bampton D; Hammond E; Clouston A; Waterhouse NJ; Stanley AC; Leveque-El Mouttie L; Chojnowski GM; Haydon A; Pavlakis N; Burge M; Brown MP; Goldstein D, 2023, 'Phase Ib open-label, multicenter study of pixatimod, an activator of TLR9, in combination with nivolumab in subjects with microsatellite-stable metastatic colorectal cancer, metastatic pancreatic ductal adenocarcinoma and other solid tumors', Journal for Immunotherapy of Cancer, 11, http://dx.doi.org/10.1136/jitc-2022-006136

Strickler JH; Satake H; George TJ; Yaeger R; Hollebecque A; Garrido-Laguna I; Schuler M; Burns TF; Coveler AL; Falchook GS; Vincent M; Sunakawa Y; Dahan L; Bajor D; Rha SY; Lemech C; Juric D; Rehn M; Ngarmchamnanrith G; Jafarinasabian P; Tran Q; Hong DS, 2023, 'Sotorasib in KRAS p.G12C-Mutated Advanced Pancreatic Cancer', New England Journal of Medicine, 388, pp. 33 - 43, http://dx.doi.org/10.1056/NEJMoa2208470

Tran B; Millward M; Lemech C; Frentzas S; Day D; Latifi A; Desai J; Wabnitz P; Kearney P; Galkin A, 2023, '1047P AXA-042, a systemically administered TLR2/6 agonist, demonstrates target engagement and TLR pathway activation in patients with advanced solid tumors', Annals of Oncology, 34, pp. s635, http://dx.doi.org/10.1016/j.annonc.2023.09.2186

Weickhardt AJ; Frentzas S; Lemech C; Srimani J; Yin J; Trepicchio WL; Gorgun C; Kichenadasse G, 2023, '711TiP A phase I/II, first-in-human, open-label, dose-escalation study of TAK-186, an EGFR × CD3ε COBRA T cell engager, in adult patients with unresectable, locally advanced, or metastatic solid tumors', Annals of Oncology, 34, pp. s492, http://dx.doi.org/10.1016/j.annonc.2023.09.1897

Vickers D; Port K; Li J; Eather S; Cranney G; Lemech C; Singarayar S, 2023, 'Novel Use of Micra AV Pacemaker for Immune Checkpoint Inhibitor-associated Myocarditis, Life-sustaining Ventricular Tachycardia and Atrioventricular Dissociation', Heart Lung and Circulation, 32, pp. s343, http://dx.doi.org/10.1016/j.hlc.2023.06.782

Kalac M; Hertzberg M; Cheah C; Ribrag V; Acosta PA; Opat S; Bachy E; Ysebaert L; Qiu L; Yi S; Nishimura N; Lemech C; Bussolari J; Deng C; Lu T; Xiu L; Van Hemelryck S; Philippar U; Guo Y; Soete V; Soriano I; Fourneau N; Gerecitano J; Morschhauser F, 2023, 'P624: PHASE 1 STUDY OF JNJ‐67856633, A FIRST‐IN‐HUMAN HIGHLY SELECTIVE MALT1 INHIBITOR, IN RELAPSED/REFRACTORY (R/R) B‐CELL NON‐HODGKIN LYMPHOMA (B‐NHL) AND CHRONIC LYMPHOCYTIC LEUKEMIA (CLL)', HemaSphere, 7, pp. e60782b9, http://dx.doi.org/10.1097/01.hs9.0000969400.60782.b9

Hertzberg M; Kalac M; Cheah CY; Ribrag V; Abrisqueta P; Opat S; Bachy E; Ysebaert L; Qiu L; Yi S; Nishimura N; Lemech C; Bussolari J; Deng C; Lu T; Xiu L; Hemelryck SV; Philippar U; Guo Y; Soete V; Paradinas IS; Fourneau N; Gerecitano J; Morschhauser F, 2023, 'PHASE 1 STUDY OF JNJ‐67856633, A FIRST‐IN‐HUMAN MALT1 INHIBITOR, IN RELAPSED/REFRACTORY (R/R) B‐CELL NON‐HODGKIN LYMPHOMA (B‐NHL) AND CHRONIC LYMPHOCYTIC LEUKEMIA (CLL)', Hematological Oncology, 41, pp. 131 - 132, http://dx.doi.org/10.1002/hon.3163_88

Pimanda JE; Thoms JAI; Hampton HR; Davidson S; Joshi S; Sarowar CH; Lim XY; Nunez AC; Kakadia PM; Pickford R; Raftery M; Hough S; Buckland G; Bailey M; Ghodke Y; Absar N; Vaughan L; Pasalic L; Fong CY; Kenealy M; Hiwase D; Stoddart R; Mohammed S; Lee L; Passam FH; Spring K; Skarratt KK; Rebeiro P; Larsen SR; Presgrave P; Stevenson WS; Ling S; Tiley C; Fuller S; Roncolato F; Enjeti AK; Hoenemann D; Lemech C; Bohlander SK; Olivier J; Hertzberg M; Unnikrishnan A; Polizzotto MN, 2022, 'In Vivo Drug Incorporation and Intracellular Dynamics of Injectable Versus Oral Azacytidine: A Phase II Open Label Multicentre Trial', Blood, 140, pp. 6927 - 6929, http://dx.doi.org/10.1182/blood-2022-157634

Mallory RM; Formica N; Pfeiffer S; Wilkinson B; Marcheschi A; Albert G; McFall H; Robinson M; Plested JS; Zhu M; Cloney-Clark S; Zhou B; Chau G; Robertson A; Maciejewski S; Hammond HL; Baracco L; Logue J; Frieman MB; Smith G; Patel N; Glenn GM; Adams M; Arya M; Athan E; Berger I; Bradley P; Briskin T; Glover R; Griffin P; Kim J; Kitchener S; Klein T; Leah A; Leelasena I; Lemech C; Lickliter J; Manning MB; Napier-Flood F; Nugent P; Thackwray S; Turner M, 2022, 'Safety and immunogenicity following a homologous booster dose of a SARS-CoV-2 recombinant spike protein vaccine (NVX-CoV2373): a secondary analysis of a randomised, placebo-controlled, phase 2 trial', Lancet Infectious Diseases, 22, pp. 1565 - 1576, http://dx.doi.org/10.1016/S1473-3099(22)00420-0

Lemech C; Argent C; Scribner C; Daniels R; Appleman JR, 2022, 'Abstract CT189: PRTX007, an optimized TLR7 agonist for systemic immunotherapy of cancers: Interim analysis of phase I study in healthy volunteers', Cancer Research, 82, pp. CT189 - CT189, http://dx.doi.org/10.1158/1538-7445.am2022-ct189

Wynne C; Schwabe C; Lemech C; Stroissnig H; Dias R; Sobierska J; Guenzi E; Otto H; Sattar A; Kay R; Haliduola HN; Berti F, 2022, 'A randomized, adaptive design, double-blind, 3-arm, parallel study assessing the pharmacokinetics and safety of AVT02, a high-concentration (100 mg/mL) Adalimumab biosimilar, in healthy adult subjects (ALVOPAD FIRST)', Expert Opinion on Investigational Drugs, 31, pp. 965 - 976, http://dx.doi.org/10.1080/13543784.2022.2035359

Falchook GS; Fu S; Lemech C; Mckean MA; Azad AA; Gan HK; Sommerhalder D; Wang JS; Tan TJY; Chee CE; Barve M; Moser J; Mooney J; Acuff N; Wang R; Marina N; Abbadessa G; Streit M; Ramusovic S; Meniawy T, 2022, '747P Phase I study of SAR444245 (SAR’245) as monotherapy (mono) and combined with pembrolizumab (pembro) or cetuximab (cetux) in patients (pts) with advanced solid tumors', Annals of Oncology, 33, pp. s885 - s886, http://dx.doi.org/10.1016/j.annonc.2022.07.873

Li BT; Falchook GS; Durm GA; Burns TF; Skoulidis F; Ramalingam SS; Spira A; Bestvina CM; Goldberg SB; Veluswamy R; Iams WT; Chiappori AA; Lemech CR; Meloni AR; Ebiana V; Dai T; Gauto DM; Varrieur TL; Snyder WJ; Govindan R, 2022, 'OA03.06 CodeBreaK 100/101: First Report of Safety/Efficacy of Sotorasib in Combination with Pembrolizumab or Atezolizumab in Advanced KRAS p.G12C NSCLC', Journal of Thoracic Oncology, 17, pp. s10 - s11, http://dx.doi.org/10.1016/j.jtho.2022.07.025

Lickliter JD; Jennens R; Lemech CR; Kichenadasse G; Cai D; Su SY-C, 2021, 'Phase 1 dose-escalation study of ACT001 in patients with recurrent glioblastoma and other advanced solid tumors.', Journal of Clinical Oncology, 39, pp. 2037 - 2037, http://dx.doi.org/10.1200/jco.2021.39.15_suppl.2037

Coward J; Mislang ARA; Frentzas S; Lemech CR; Nagrial A; Jin X; Li B; Wang ZM; Kwek KY; Xia Y, 2021, 'Safety and efficacy of AK112, an anti-PD-1/VEGF-A bispecific antibody, in patients with advanced solid tumors in a phase I dose escalation study.', Journal of Clinical Oncology, 39, pp. 2515 - 2515, http://dx.doi.org/10.1200/jco.2021.39.15_suppl.2515

Lemech CR; Kichenadasse G; Marschner J-P; Alevizopoulos K; Otterlei M; Millward M, 2021, 'Safety profile and disease stabilization in late stage, heavily pretreated, solid tumor patients in a first-in-human (FIH) study of ATX-101, a drug targeting proliferating cell nuclear antigen (PCNA).', Journal of Clinical Oncology, 39, pp. 3067 - 3067, http://dx.doi.org/10.1200/jco.2021.39.15_suppl.3067

Lee DH; Roohullah A; Cho BC; Lemech CR; de Souza PL; Millward M; Choi JY; Park KE; Lee M; Kim Y; Shin Y; Han J-Y, 2021, 'Trial in progress: A phase 1-2 multicenter, open-label, dose-escalation and dose-expansion study to evaluate the safety, pharmacokinetics, pharmacodynamics, and antitumor activity of ABN401 in patients with advanced solid tumors.', Journal of Clinical Oncology, 39, pp. tps3157 - tps3157, http://dx.doi.org/10.1200/jco.2021.39.15_suppl.tps3157

Lee DH; Roohullah A; Cho BC; Lemech C; de Souza P; Millward M; Choi J; Park KE; Lee M; Kim Y; Park S; Lee J; Kim J; Shin YK; Han J-Y, 2021, '1358P Phase I dose-escalation study to evaluate safety and clinical activity of c-MET inhibitor ABN401 in patients with advanced solid tumor', Annals of Oncology, 32, pp. s1029 - s1030, http://dx.doi.org/10.1016/j.annonc.2021.08.1958

Coward J; Frentzas S; Mislang A; Gao B; Lemech C; Jin X; Li B; Wang M; Kwek KY; Zhou Y; Xia Y, 2021, '427 Efficacy and safety of AK112, an anti-PD-1/VEGF-A bispecific antibody, in patients with platinum-resistant/refractory epithelial ovarian cancer in a Phase 1 study', Journal for ImmunoTherapy of Cancer, 9, pp. a457 - a457, http://dx.doi.org/10.1136/jitc-2021-sitc2021.427

Lemech C; Woodward N; Chan N; Mortimer J; Naumovski L; Nuthalapati S; Tong B; Jiang F; Ansell P; Ratajczak CK; Sachdev J, 2020, 'A first-in-human, phase 1, dose-escalation study of ABBV-176, an antibody-drug conjugate targeting the prolactin receptor, in patients with advanced solid tumors', Investigational New Drugs, 38, pp. 1815 - 1825, http://dx.doi.org/10.1007/s10637-020-00960-z

Perry N; Moss S; Dixon S; Milner S; Mokbel K; Lemech C; Arkenau HT; Duffy S; Pinker K, 2020, 'Mammographic breast density and urbanization: Interactions with BMI, environmental, lifestyle, and other patient factors', Diagnostics, 10, http://dx.doi.org/10.3390/diagnostics10060418

Coward J; Lemech CR; Mislang ARA; Parakh S; Underhill C; Nagrial A; Jin X; Li B; Wang ZM; Kwek KY; Xia Y, 2020, 'A phase I study of AK112, a bispecific antibody that targets PD-1 and VEGF co-expressing T cells, in patients with advanced solid tumors.', Journal of Clinical Oncology, 38, pp. tps3155 - tps3155, http://dx.doi.org/10.1200/jco.2020.38.15_suppl.tps3155

Berry S; Giraldo N; Nguyen P; Green B; Xu H; Ogurtsova A; Soni A; Succaria F; Wang D; Roberts C; Stein J; Engle E; Pardoll D; Anders R; Cottrell T; Taube JM; Tran B; Voskoboynik M; Kuo J; Bang YL; Chung HC; Ahn MJ; Kim SW; Perera A; Freeman D; Achour I; Faggioni R; Xiao F; Ferte C; Lemech C; Meric-Bernstam F; Werner T; Hodi S; Messersmith W; Lewis N; Talluto C; Dostalek M; Tao A; McWhirter S; Trujillo D; Luke J; Xu C; Bomarelli B; Qi J; Qin G; Yu H; Jenkins M; Lo KM; Halle JP; Lan Y; Taylor M; Vogelzang N; Cohn A; Stepan D; Shumaker R; Dutcus C; Guo M; Schmidt E; Rasco D; Brose M; Di Simone C; Jain S; Richards D; Encarnacion C; Vogelzeng N; Mier J; An J; Yang YY; Lee WH; Yang J; Kim JK; Kim HG; Paek SH; Lee JW; Woo J; Kim JB; Kwon H; Lim W; Paik NS; Kim YK; Moon BI; Janku F; Tan D; Martin-Liberal J; Takahashi S; Geva R; Gucalp A; Chen X; Subramanian K; Mataraza J; Wheler J; Bedard P, 2019, 'Correction: 33rd Annual meeting & pre-conference programs of the Society for Immunotherapy of Cancer (SITC 2018) (Journal for ImmunoTherapy of Cancer (2018) 6:Suppl 1 DOI: 10.1186/s40425-018-0422-y)', Journal for Immunotherapy of Cancer, 7, http://dx.doi.org/10.1186/s40425-019-0519-y

Coward J; Lemech C; Meniawy T; Dupont CD; Gonzalez AM; Lim M; Savitsky D; Carini M; Hu S; Shebanova O; Dow E; Ortuzar W; Buell JS; Stein RB; Youssoufian H, 2018, 'Phase I/II study of CTLA-4 inhibitor AGEN1884 + PD-1 Inhibitor AGEN2034 in patients with advanced/refractory solid tumors, with expansion into 2L cervical cancer and solid tumors', Annals of oncology : official journal of the European Society for Medical Oncology, 29, pp. viii417, http://dx.doi.org/10.1093/annonc/mdy288.041

Lickliter JD; Jennens R; Lemech CR; Su SY-C; Chen Y, 2018, 'Phase 1 dose-escalation study of ACT001 in patients with recurrent glioblastoma and other advanced solid tumors.', Journal of Clinical Oncology, 36, pp. e14048 - e14048, http://dx.doi.org/10.1200/jco.2018.36.15_suppl.e14048

Mateo J; Ganji G; Lemech C; Burris HA; Han SW; Swales K; Decordova S; DeYoung MP; Smith DA; Kalyana-Sundaram S; Wu J; Motwani M; Kumar R; Tolson JM; Rha SY; Chung HC; Eder JP; Sharma S; Bang YJ; Infante JR; Yan L; De Bono JS; Arkenau HT, 2017, 'A first-time-in-human study of GSK2636771, a phosphoinositide 3 kinase beta-selective inhibitor, in patients with advanced solid tumors', Clinical Cancer Research, 23, pp. 5981 - 5992, http://dx.doi.org/10.1158/1078-0432.CCR-17-0725

Goldstein D; Lemech C; Valle J, 2017, 'New molecular and immunotherapeutic approaches in biliary cancer', ESMO Open, 2, pp. e000152, http://dx.doi.org/10.1136/esmoopen-2016-000152

Uccello M; Moschetta M; Mak G; Martynyuk N; Hauser J; Bassett S; Voskoboynik M; Lemech C; Rafii S; Arkenau H-T, 2017, 'BRAF +/- MEK inhibition in patients (pts) with BRAF-mutant (mut) metastatic colorectal cancer (mCRC): The Sarah Cannon Research Institute UK’s experience.', Journal of Clinical Oncology, 35, pp. 645 - 645, http://dx.doi.org/10.1200/jco.2017.35.4_suppl.645

Soria JC; Gan HK; Blagden SP; Plummer R; Arkenau HT; Ranson M; Evans TRJ; Zalcman G; Bahleda R; Hollebecque A; Lemech C; Dean E; Brown J; Gibson D; Peddareddigari V; Murray S; Nebot N; Mazumdar J; Swartz L; Auger KR; Fleming RA; Singh R; Millward M, 2016, 'A phase I, pharmacokinetic and pharmacodynamic study of GSK2256098, a focal adhesion kinase inhibitor, in patients with advanced solid tumors', Annals of Oncology, 27, pp. 2268 - 2274, http://dx.doi.org/10.1093/annonc/mdw427

Plesner T; Arkenau HT; Gimsing P; Krejcik J; Lemech C; Minnema MC; Lassen U; Laubach JP; Palumbo A; Lisby S; Basse L; Wang J; Sasser AK; Guckert ME; De Boer C; Khokhar NZ; Yeh H; Clemens PL; Ahmadi T; Lokhorst HM; Richardson PG, 2016, 'Phase 1/2 study of daratumumab, lenalidomide, and dexamethasone for relapsed multiple myeloma', Blood, 128, pp. 1821 - 1828, http://dx.doi.org/10.1182/blood-2016-07-726729

Hughes A; Landers D; Arkenau HT; Shah S; Stephens R; Mahal A; Simmons M; Lemech C; Royle J, 2016, 'Erratum to: Development and Evaluation of a New Technological Way of Engaging Patients and Enhancing Understanding of Drug Tolerability in Early Clinical Development: PROACT (Adv Ther, (2016), 33, (1012-1024), 10.1007/s12325-016-0335-4)', Advances in Therapy, 33, pp. 1677 - 1678, http://dx.doi.org/10.1007/s12325-016-0390-x

Lemech CR; Williams R; Thompson SR; McCaughan B; Chin M, 2016, 'Treatment of breast cancer 2 (BRCA2)-mutant follicular dendritic cell sarcoma with a poly ADP-ribose polymerase (PARP) inhibitor: A case report', BMC Research Notes, 9, http://dx.doi.org/10.1186/s13104-016-2189-x

Lemech CR; Ensell L; Paterson JC; Eminowicz G; Lowe H; Arora R; Arkenau HT; Widschwendter M; MacDonald N; Olaitan A; Mould T; Meyer T; Hartley J; Mitra A; Ledermann JA; McCormack M; Kristeleit RS, 2016, 'Enumeration and Molecular Characterisation of Circulating Tumour Cells in Endometrial Cancer', Oncology Switzerland, 91, pp. 48 - 54, http://dx.doi.org/10.1159/000445999

Hughes A; Landers D; Arkenau HT; Shah S; Stephens R; Mahal A; Simmons M; Lemech C; Royle J, 2016, 'Development and Evaluation of a New Technological Way of Engaging Patients and Enhancing Understanding of Drug Tolerability in Early Clinical Development: PROACT', Advances in Therapy, 33, pp. 1012 - 1024, http://dx.doi.org/10.1007/s12325-016-0335-4

Bendell JC; Patel MR; Yoshida K; Seraj J; Weaver R; Lemech C; Todaro TG; Pant S; Arkenau HT, 2016, 'Phase 1 study of cardiac safety of TAS-102 in patients with advanced solid tumors', Cancer Chemotherapy and Pharmacology, 77, pp. 1275 - 1283, http://dx.doi.org/10.1007/s00280-016-3031-9

Laille E; Patel M; Jones SF; Burris HA; Infante J; Lemech C; Liu L; Arkenau HT, 2015, 'Evaluation of CYP3A-mediated drug-drug interactions with romidepsin in patients with advanced cancer', Journal of Clinical Pharmacology, 55, pp. 1378 - 1385, http://dx.doi.org/10.1002/jcph.560

Lemech C; Dua D; Newmark J; Saggese M; Simmons E; Spiliopoulou P; Arkenau HT, 2015, 'Patients' perceptions of research biopsies in phase i oncology trials', Oncology Switzerland, 88, pp. 95 - 102, http://dx.doi.org/10.1159/000368161

Plesner T; Arkenau H-T; Lokhorst HM; Gimsing P; Krejcik J; Lemech C; Minnema MC; Lassen U; Laubach JP; Ahmadi T; Yeh H; Guckert ME; Feng H; Brun NC; Lisby S; Basse L; Palumbo A; Richardson PG, 2014, 'Safety and Efficacy of Daratumumab with Lenalidomide and Dexamethasone in Relapsed or Relapsed, Refractory Multiple Myeloma', Blood, 124, pp. 84, http://dx.doi.org/10.1182/blood.v124.21.84.84

Hillman RJ; Garland SM; Gunathilake MPW; Stevens M; Kumaradevan N; Lemech C; Ward RL; Meagher A; McHugh L; Jin F; Carroll S; Goldstein D; Grulich AE; Tabrizi SN, 2014, 'Human papillomavirus (HPV) genotypes in an Australian sample of anal cancers.', Int J Cancer, 135, pp. 996 - 1001, http://dx.doi.org/10.1002/ijc.28730

Baird R; Cresti N; Beddowes E; Saggese M; Flynn M; Garcia Corbacho J; Gao F; Lemech C; Donaldson K; Posner J; Kawabata I; Forster M; Arkenau H; Plummer R; Jodrell D; Spicer J, 2013, 'Abstract P4-12-24: Phase I trial of S-222611, a dual tyrosine kinase inhibitor of EGFR and HER2, with preliminary evidence of efficacy in patients (pts) with heavily-pretreated HER2-positive metastatic breast cancer', Cancer Research, 73, pp. p4-12-24-p4-12-24, http://dx.doi.org/10.1158/0008-5472.sabcs13-p4-12-24

Jones A; Teschendorff AE; Li Q; Hayward JD; Kannan A; Mould T; West J; Zikan M; Cibula D; Fiegl H; Lee SH; Wik E; Hadwin R; Arora R; Lemech C; Turunen H; Pakarinen P; Jacobs IJ; Salvesen HB; Bagchi MK; Bagchi IC; Widschwendter M, 2013, 'Role of DNA Methylation and Epigenetic Silencing of HAND2 in Endometrial Cancer Development', Plos Medicine, 10, http://dx.doi.org/10.1371/journal.pmed.1001551

Saggese M; Dua D; Simmons E; Lemech C; Arkenau H-T, 2013, 'Research biopsies in the context of early phase oncology studies: clinical and ethical considerations', Oncology Reviews, pp. e5 - e5, http://dx.doi.org/10.4081/oncol.2013.232

Lemech CR; Arkenau HT, 2013, 'The future is here: Tumour profiling in day-to-day clinical practice', Drug Discovery Today, 18, pp. 689 - 691, http://dx.doi.org/10.1016/j.drudis.2013.06.006

Back to profile page