Select Publications

Journal articles

Khan A; Gamble LD; Upton DH; Ung C; Yu DMT; Ehteda A; Pandher R; Mayoh C; Hébert S; Jabado N; Kleinman CL; Burns MR; Norris MD; Haber M; Tsoli M; Ziegler DS, 2021, 'Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas', Nature Communications, vol. 12, pp. 971, http://dx.doi.org/10.1038/s41467-021-20896-z

Ung C; Tsoli M; Liu J; Cassano D; Pocoví-Martínez S; Upton DH; Ehteda A; Mansfeld FM; Failes TW; Farfalla A; Katsinas C; Kavallaris M; Arndt GM; Vittorio O; Cirillo G; Voliani V; Ziegler DS, 2021, 'Doxorubicin-loaded gold nanoarchitectures as a therapeutic strategy against diffuse intrinsic pontine glioma', Cancers, vol. 13, pp. 1 - 20, http://dx.doi.org/10.3390/cancers13061278

Upton DH; Popovic K; Fulton R; Kassiou M, 2020, 'Anaesthetic-dependent changes in gene expression following acute and chronic exposure in the rodent brain', Scientific Reports, vol. 10, http://dx.doi.org/10.1038/s41598-020-66122-6

Tsoli M; Shen H; Mayoh C; Franshaw L; Ehteda A; Upton D; Carvalho D; Vinci M; Meel MH; van Vuurden D; Plessier A; Castel D; Drissi R; Farrell M; Cryan J; Crimmins D; Caird J; Pears J; Francis S; Ludlow LEA; Carai A; Mastronuzzi A; Liu B; Hansford J; Gottardo NG; Hassall T; Kirby M; Fouladi M; Hawkins C; Monje M; Grill J; Jones C; Hulleman E; Ziegler DS, 2019, 'Correction to: International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma (Journal of Neuro-Oncology, (2019), 141, 2, (253-263), 10.1007/s11060-018-03038-2)', Journal of Neuro-Oncology, vol. 141, pp. 265, http://dx.doi.org/10.1007/s11060-018-03060-4

Tsoli M; Shen H; Mayoh C; Franshaw L; Ehteda A; Upton D; Carvalho D; Vinci M; Meel MH; van Vuurden D; Plessier A; Castel D; Drissi R; Farrell M; Cryan J; Crimmins D; Caird J; Pears J; Francis S; Ludlow LEA; Carai A; Mastronuzzi A; Liu B; Hansford J; Gottardo N; Hassall T; Kirby M; Fouladi M; Hawkins C; Monje M; Grill J; Jones C; Hulleman E; Ziegler DS, 2019, 'International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma', Journal of Neuro-Oncology, vol. 141, pp. 253 - 263, http://dx.doi.org/10.1007/s11060-018-03038-2

Upton DH; Walters KA; McTavish KJ; Holt J; Handelsman DJ; Allan CM, 2018, 'Reproductive failure in mice expressing transgenic follicle-stimulating hormone is not caused by loss of oocyte quality', Biology of Reproduction, vol. 98, pp. 491 - 500, http://dx.doi.org/10.1093/biolre/ioy015

Upton DH; Walters KA; Allavena RE; Jimenez M; Desai R; Handelsman DJ; Allan CM, 2016, 'Global or Granulosa Cell-Specific Pten Mutations in Combination with Elevated FSH Levels Fail to Cause Ovarian Tumours in Mice', Hormones and Cancer, vol. 7, pp. 316 - 326, http://dx.doi.org/10.1007/s12672-016-0272-3

Hazra R; Upton D; Desai R; Noori O; Jimenez M; Handelsman DJ; Allan CM, 2016, 'Elevated expression of the sertoli cell androgen receptor disrupts male fertility', American Journal of Physiology - Endocrinology and Metabolism, vol. 311, pp. E396 - E404, http://dx.doi.org/10.1152/ajpendo.00159.2016

Powell KL; Stevens V; Upton DH; McCracken SA; Simpson AM; Cheng Y; Tasevski V; Morris JM; Ashton AW, 2016, 'Role for the thromboxane A 2 receptor β-isoform in the pathogenesis of intrauterine growth restriction', Scientific Reports, vol. 6, http://dx.doi.org/10.1038/srep28811

Upton DH; Fuller ES; Colvin EK; Walters KA; Jimenez M; Desai R; Handelsman DJ; Howell VM; Allan CM, 2015, 'Granulosa Cell-Specific Brca1 Loss Alone or Combined with Trp53 Haploinsufficiency and Transgenic FSH Expression Fails to Induce Ovarian Tumors', Hormones and Cancer, vol. 6, pp. 142 - 152, http://dx.doi.org/10.1007/s12672-015-0222-5

Hazra R; Upton D; Jimenez M; Desai R; Handelsman DJ; Allan CM, 2014, 'In vivo actions of the sertoli cell glucocorticoid receptor', Endocrinology, vol. 155, pp. 1120 - 1130, http://dx.doi.org/10.1210/en.2013-1940

Hazra R; Corcoran L; Robson M; McTavish KJ; Upton D; Handelsman DJ; Allan CM, 2013, 'Temporal role of sertoli cell androgen receptor expression in spermatogenic development', Molecular Endocrinology, vol. 27, pp. 12 - 24, http://dx.doi.org/10.1210/me.2012-1219

Conference Papers

Ung C; Tsoli M; Liu J; Cassano D; Upton D; Ehteda A; Mansfield F; Failes T; Kavallaris M; Arndt G; Vittorio O; Voliani V; Cirilo G; Ziegler DS, 2020, 'NANOPARTICLE DELIVERY OF DOXORUBICIN FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 286 - 286, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100048&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts

Upton D; George S; Liu J; Cai D; Su SY-C; Manoharan N; Foresto S; Hassall T; Tsoli M; Ziegler D, 2021, 'ACT001-A PROMISING THERAPEUTIC FOR DIFFUSE INTRINSIC PONTINE GLIOMAS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 23, pp. 20 - 20, http://dx.doi.org/10.1093/neuonc/noab090.080

Ung C; Upton D; Tsoli M; Ziegler D, 2021, 'HGG-10. THE BLOOD-BRAIN BARRIER IN DIPG: INVESTIGATING REGION-SPECIFIC DIFFERENCES IN PERMEABILITY', in Neuro-Oncology, Oxford University Press (OUP), Vol. 23, pp. i19 - i19, http://dx.doi.org/10.1093/neuonc/noab090.076

Khan A; Gamble L; Upton D; Yu D; Pandher R; Mayoh C; Burns MR; Norris MD; Haber M; Tsoli M; Ziegler DS, 2021, 'POLYAMINE PATHWAY INHIBITION IS A POTENT NOVEL THERAPEUTIC STRATEGY AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 23, pp. 40 - 41, http://dx.doi.org/10.1093/neuonc/noab090.163

Upton D; Valvi S; Liu J; Yeung N; George S; Ung C; Khan A; Franshaw L; Ehteda A; Shen H; Orienti I; Farruggia G; Reynolds P; Tsoli M; Ziegler D, 2021, 'POTENTIAL NEW THERAPIES FOR DIFFUSE INTRINSIC PONTINE GLIOMAS IDENTIFIED THROUGH HIGH THROUGHPUT DRUG SCREENING', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 23, pp. 42 - 42, http://dx.doi.org/10.1093/neuonc/noab090.169

Ung C; Tsoli M; Liu J; Cassano D; Upton D; Ehteda A; Mansfield F; Failes T; Kavallaris M; Arndt G; Vittorio O; Voliani V; Cirilo G; Ziegler DS, 2020, 'DDEL-12. NANOPARTICLE DELIVERY OF DOXORUBICIN FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii286 - iii286, http://dx.doi.org/10.1093/neuonc/noaa222.047

Upton D; Valvi S; Liu J; Yeung N; George S; Ung C; Khan A; Franshaw L; Ehteda A; Shen H; Orienti I; Farruggia G; Nath C; Reynolds P; Tsoli M; Ziegler D, 2020, 'DIPG-07. HIGH THROUGHPUT DRUG SCREENING IDENTIFIES POTENTIAL NEW THERAPIES FOR DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPGs)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii288 - iii288, http://dx.doi.org/10.1093/neuonc/noaa222.058

Khan A; Gamble L; Upton D; Yu D; Ehteda A; Pandher R; Mayoh C; Burns M; Norris M; Haber M; Tsoli M; Ziegler D, 2020, 'DIPG-15. POLYAMINE PATHWAY INHIBITION IS A POTENT NOVEL THERAPEUTIC STRATEGY AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii289 - iii290, http://dx.doi.org/10.1093/neuonc/noaa222.065

Ehteda A; Franshaw L; Liu J; Joshi S; Simon S; Pang CNI; Giorgi F; Pandher R; Ung C; Tolhurst O; Mayoh C; Khan A; Hayden E; Gopalakrishnan A; Trebilcock P; Upton D; Lehmann R; George S; Vittorio O; Tsoli M; Gurova K; Gudkov AG; Norris MD; Haber M; Ziegler DS, 2020, 'DIPG-27. TARGETING FACILITATES CHROMATIN TRANSCRIPTION (FACT) AS A NOVEL STRATEGY FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) THAT ENHANCES RESPONSE TO HISTONE DEACETYLASE (HDAC) INHIBITION', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii292 - iii292, http://dx.doi.org/10.1093/neuonc/noaa222.076


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