By Dr Dannielle Upton

Journal articles

Upton DH; Liu J; George SM; Valvi S; Ung C; Rayner BS; Gopalakrishnan A; Pandher R; Khan A; Venkat P; Mayoh C; Holliday H; Yeung N; Nguyen H; Franshaw L; Ehteda A; Shen H; Farruggia G; Orienti I; Reynolds CP; Tsoli M; Ziegler DS, 2025, 'High-throughput in vitro drug screening and in vivo studies identify fenretinide as a brain-penetrant DMG therapeutic.', Neuro Oncol, http://dx.doi.org/10.1093/neuonc/noaf035

Upton DH; Ziegler DS; Tsoli M, 2024, 'Development of Orthotopic Patient-Derived Xenograft Models of Pediatric Intracranial Tumors', , 2806, pp. 75 - 90, http://dx.doi.org/10.1007/978-1-0716-3858-3_7

Ung C; Upton D; Venkat P; Pandher R; Mayoh C; Tsoli M; Ziegler D, 2023, 'DDEL-07. BARRIER TO PROGRESS: DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) INDUCES A TIGHTENED BLOOD-BRAIN BARRIER PHENOTYPE', Neuro-Oncology, 25, pp. v102 - v103, http://dx.doi.org/10.1093/neuonc/noad179.0386

Hayden E; Franshaw L; Upton D; Liu J; Nguyen H; Joshi S; Tsoli M; Dolman E; Rayner B; Ziegler D, 2023, 'Abstract 1561: Preclinical examination of PLK1 inhibitors for the treatment of diffuse midline gliomas', Cancer Research, 83, pp. 1561 - 1561, http://dx.doi.org/10.1158/1538-7445.am2023-1561

Upton DH; Ung C; George SM; Tsoli M; Kavallaris M; Ziegler DS, 2022, 'Challenges and opportunities to penetrate the blood-brain barrier for brain cancer therapy', Theranostics, 12, pp. 4734 - 4752, http://dx.doi.org/10.7150/THNO.69682

Khan A; Gamble LD; Upton DH; Ung C; Yu DMT; Ehteda A; Pandher R; Mayoh C; Hébert S; Jabado N; Kleinman CL; Burns MR; Norris MD; Haber M; Tsoli M; Ziegler DS, 2021, 'Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas', Nature Communications, 12, pp. 971, http://dx.doi.org/10.1038/s41467-021-20896-z

Ung C; Tsoli M; Liu J; Cassano D; Pocoví-Martínez S; Upton DH; Ehteda A; Mansfeld FM; Failes TW; Farfalla A; Katsinas C; Kavallaris M; Arndt GM; Vittorio O; Cirillo G; Voliani V; Ziegler DS, 2021, 'Doxorubicin-loaded gold nanoarchitectures as a therapeutic strategy against diffuse intrinsic pontine glioma', Cancers, 13, pp. 1 - 20, http://dx.doi.org/10.3390/cancers13061278

Upton DH; Popovic K; Fulton R; Kassiou M, 2020, 'Anaesthetic-dependent changes in gene expression following acute and chronic exposure in the rodent brain', Scientific Reports, 10, pp. 9366, http://dx.doi.org/10.1038/s41598-020-66122-6

Tsoli M; Shen H; Mayoh C; Franshaw L; Ehteda A; Upton D; Carvalho D; Vinci M; Meel MH; van Vuurden D; Plessier A; Castel D; Drissi R; Farrell M; Cryan J; Crimmins D; Caird J; Pears J; Francis S; Ludlow LEA; Carai A; Mastronuzzi A; Liu B; Hansford J; Gottardo NG; Hassall T; Kirby M; Fouladi M; Hawkins C; Monje M; Grill J; Jones C; Hulleman E; Ziegler DS, 2019, 'Correction to: International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma (Journal of Neuro-Oncology, (2019), 141, 2, (253-263), 10.1007/s11060-018-03038-2)', Journal of Neuro-Oncology, 141, pp. 265, http://dx.doi.org/10.1007/s11060-018-03060-4

Tsoli M; Shen H; Mayoh C; Franshaw L; Ehteda A; Upton D; Carvalho D; Vinci M; Meel MH; van Vuurden D; Plessier A; Castel D; Drissi R; Farrell M; Cryan J; Crimmins D; Caird J; Pears J; Francis S; Ludlow LEA; Carai A; Mastronuzzi A; Liu B; Hansford J; Gottardo N; Hassall T; Kirby M; Fouladi M; Hawkins C; Monje M; Grill J; Jones C; Hulleman E; Ziegler DS, 2019, 'International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma', Journal of Neuro-Oncology, 141, pp. 253 - 263, http://dx.doi.org/10.1007/s11060-018-03038-2

Upton DH; Walters KA; McTavish KJ; Holt J; Handelsman DJ; Allan CM, 2018, 'Reproductive failure in mice expressing transgenic follicle-stimulating hormone is not caused by loss of oocyte quality', Biology of Reproduction, 98, pp. 491 - 500, http://dx.doi.org/10.1093/biolre/ioy015

Upton DH; Walters KA; Allavena RE; Jimenez M; Desai R; Handelsman DJ; Allan CM, 2016, 'Global or Granulosa Cell-Specific Pten Mutations in Combination with Elevated FSH Levels Fail to Cause Ovarian Tumours in Mice', Hormones and Cancer, 7, pp. 316 - 326, http://dx.doi.org/10.1007/s12672-016-0272-3

Hazra R; Upton D; Desai R; Noori O; Jimenez M; Handelsman DJ; Allan CM, 2016, 'Elevated expression of the sertoli cell androgen receptor disrupts male fertility', American Journal of Physiology - Endocrinology and Metabolism, 311, pp. E396 - E404, http://dx.doi.org/10.1152/ajpendo.00159.2016

Powell KL; Stevens V; Upton DH; McCracken SA; Simpson AM; Cheng Y; Tasevski V; Morris JM; Ashton AW, 2016, 'Role for the thromboxane A 2 receptor β-isoform in the pathogenesis of intrauterine growth restriction', Scientific Reports, 6, http://dx.doi.org/10.1038/srep28811

Upton DH; Fuller ES; Colvin EK; Walters KA; Jimenez M; Desai R; Handelsman DJ; Howell VM; Allan CM, 2015, 'Granulosa Cell-Specific Brca1 Loss Alone or Combined with Trp53 Haploinsufficiency and Transgenic FSH Expression Fails to Induce Ovarian Tumors', Hormones and Cancer, 6, pp. 142 - 152, http://dx.doi.org/10.1007/s12672-015-0222-5

Hazra R; Upton D; Jimenez M; Desai R; Handelsman DJ; Allan CM, 2014, 'In vivo actions of the sertoli cell glucocorticoid receptor', Endocrinology, 155, pp. 1120 - 1130, http://dx.doi.org/10.1210/en.2013-1940

Hazra R; Corcoran L; Robson M; McTavish KJ; Upton D; Handelsman DJ; Allan CM, 2013, 'Temporal role of sertoli cell androgen receptor expression in spermatogenic development', Molecular Endocrinology, 27, pp. 12 - 24, http://dx.doi.org/10.1210/me.2012-1219

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