By Dr David Humphreys

Journal articles

Ohanian M; Humphreys DT; Anderson E; Preiss T; Fatkin D, 2013, 'A heterozygous variant in the human cardiac miR-133 gene, MIR133A2, alters miRNA duplex processing and strand abundance.', BMC Genetics, 14, http://dx.doi.org/10.1186/1471-2156-14-18

Li CCY; Eaton SA; Young PE; Lee M; Shuttleworth R; Humphreys DT; Grau GE; Combes V; Bebawy M; Gong J; Brammah S; Buckland ME; Suter CM, 2013, 'Glioma microvesicles carry selectively packaged coding and noncoding RNAs which alter gene expression in recipient cells', RNA Biology, 10, pp. 1333 - 1344, http://dx.doi.org/10.4161/rna.25281

Samaraweera SE; O'Keefe LV; Van Eyk CL; Lawlor KT; Humphreys DT; Suter CM; Richards RI, 2013, 'Modeling and analysis of repeat RNA toxicity in drosophila', Methods in Molecular Biology, 1017, pp. 173 - 192, http://dx.doi.org/10.1007/978-1-62703-438-8_13

Humphreys DT; Hynes CJ; Patel HR; Wei GH; Cannon L; Fatkin D; Suter CM; Clancy JL; Preiss T, 2012, 'Complexity of murine cardiomyocyte miRNA biogenesis, sequence variant expression and function.', PLoS One, 7, pp. e30933, http://dx.doi.org/10.1371/journal.pone.0030933

Humphreys DT; Preiss T; Hentze M, 2012, 'Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins', Cell, 149, pp. 1393 - 1406, http://dx.doi.org/10.1016/j.cell.2012.04.031

Squires JE; Patel HR; Nousch M; Sibbritt T; Humphreys DT; Parker BJ; Suter CM; Preiss T, 2012, 'Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA', Nucleic Acids Research, 40, pp. 5023 - 5033, http://dx.doi.org/10.1093/nar/gks144

Preiss T; Clancy JL; Wei G; Echner N; Humphreys D; Beilharz TH, 2011, 'mRNA isoform diversity can obscure detection of miRNA-mediated control of translation', RNA - a Publication of the RNA Society, 17, pp. 1025 - 1031

Schonrock N; Humphreys D; Preiss T; Gotz J, 2011, 'Target Gene Repression Mediated by miRNAs miR-181c and miR-9 Both of Which Are Down-regulated by Amyloid-beta', Journal of Molecular Neuroscience, 46, pp. 324 - 335, http://dx.doi.org/10.1007/s12031-011-9587-2

Larance M; Rowland AF; Hoehn KL; Humphreys D; Preiss T; Guilhaus M; James DE, 2010, 'Global phosphoproteomics identifies a major role for AKT and 14-3-3 in regulating EDC3', Molecular and Cellular Proteomics, 9, pp. 682 - 694, http://dx.doi.org/10.1074/mcp.M900435-MCP200

Schonrock N; Yazi DK; Humphreys D; Staufenbiel M; Ittner LM; Preiss T; Gotz J; Ke Y, 2010, 'Neuronal microRNA deregulation in response to Alzheimer's disease amyloid-beta', PLoS One, 5, pp. e11070, http://dx.doi.org/10.1371/journal.pone.0011070

Beilharz TH; Humphreys D; Clancy JL; Thermann R; Martin DI; Hentze MW; Preiss T, 2009, 'MicroRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells', PLoS One, 4

Clancy JL; Nousch M; Humphreys D; Westman B; Beilharz TH; Preiss T, 2007, 'Methods to analyze microRNA-mediated control of mRNA translation', Methods in Enzymology, 431, pp. 83 - 112

Lu DP; Read RL; Humphreys DT; Battah FM; Martin DIK; Rasko JEJ, 2005, 'PCR-based expression analysis and identification of microRNAs.', Journal of RNAi and gene silencing : an international journal of RNA and gene targeting research, 1, pp. 44 - 49

Humphreys D; Westman B; Martin DI; Preiss T, 2005, 'MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function', Proceedings of the National Academy of Sciences of the United States of America, 102, pp. 16961 - 16966

Hochgrebe TT; Humphreys D; Wilson MR; Easterbrook-Smith SB, 1999, 'A reexamination of the role of clusterin as a complement regulator', Experimental Cell Research, 249, pp. 13 - 21, http://dx.doi.org/10.1006/excr.1999.4459

Humphreys DT; Carver JA; Easterbrook-Smith SB; Wilson MR, 1999, 'Clusterin has chaperone-like activity similar to that of small heat shock proteins', Journal of Biological Chemistry, 274, pp. 6875 - 6881, http://dx.doi.org/10.1074/jbc.274.11.6875

Humphreys DT; Wilson MR, 1999, 'Modes of L929 cell death induced by TNF-α and other cytotoxic agents', Cytokine, 11, pp. 773 - 782, http://dx.doi.org/10.1006/cyto.1998.0492

Humphreys D; Hochgrebe TT; Easterbrook-Smith SB; Tenniswood MP; Wilson MR, 1997, 'Effects of clusterin overexpression on TNFα- and TGFβ-mediated death of L929 cells', Biochemistry, 36, pp. 15233 - 15243, http://dx.doi.org/10.1021/bi9703507

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