By Dr David Humphreys

Preprints

Thekkedam C; Humphreys D; Naval-Sanchez M; Nicks A; Harvey R; Contreras O, 2026, A scalable MNase-seq framework for reproducible nucleosome profiling across pluripotent stem cell and cardiomyocyte models, http://dx.doi.org/10.64898/2026.06.08.731013

, 2025, Impaired yolk sac NAD metabolism disrupts murine embryogenesis with relevance to human birth defects, http://dx.doi.org/10.7554/eLife.97649

Bozon K; Cuny H; Sheng DZ; Martin EMMA; Sipka A; Young P; Humphreys DT; Dunwoodie SL, 2025, Impaired yolk sac NAD metabolism disrupts murine embryogenesis with relevance to human birth defects, http://dx.doi.org/10.7554/elife.97649.2

Bozon K; Cuny H; Sheng DZ; Martin EMMA; Young P; Humphreys DT; Dunwoodie SL, 2024, Impaired yolk sac NAD metabolism disrupts murine embryogenesis with relevance to human birth defects, http://dx.doi.org/10.7554/elife.97649.1

Cropley J; Eaton S; Aiken A; Young P; Giannoulatou E; Ho JWK; Buckland M; Keam S; Hutvagner G; Humphreys D; Langley K; Henstridge D; Martin D; Febbraio M; Suter C, 2016, Grand paternal inheritance of an acquired metabolic trait induced by ancestral obesity is associated with sperm RNA, http://dx.doi.org/10.1101/042101

Cornejo-Páramo P; Zhang X; Louis L; Yang Y-H; Li Z; Humphreys D; Wong ES, A Bag-Of-Motif Model Captures Cell States at Distal Regulatory Sequences, http://dx.doi.org/10.1101/2024.01.03.574012

Zhuang X; Wang Q; Joost S; Ferrena A; Humphreys DT; Li Z; Blum M; Bastl K; Ding S; Landais Y; Zhan Y; Zhao Y; Chaligne R; Lee J-H; Carrasco SE; Bhanot UK; Koche RP; Bott MJ; Katajisto P; Soto-Feliciano YM; Pisanic T; Thomas T; Zheng D; Wong ES; Tammela T, Aging limits stemness and tumorigenesis in the lung by reprogramming iron homeostasis, http://dx.doi.org/10.1101/2024.06.23.600305

Murtha LA; Hardy SA; Mabotuwana NS; Bigland MJ; Bailey T; Raguram K; Liu S; Ngo DT; Sverdlov AL; Tomin T; Birner-Gruenberger R; Hume RD; Iismaa SE; Humphreys DT; Patrick R; Chong JJH; Lee RJ; Harvey RP; Graham RM; Rainer PP; Boyle AJ, Fibulin-3 is necessary to prevent cardiac rupture following myocardial infarction, http://dx.doi.org/10.21203/rs.3.rs-3055737/v1

Bozon K; Cuny H; Sheng DZ; Martin EMMA; Sipka A; Young P; Humphreys DT; Dunwoodie SL, Impaired yolk sac NAD metabolism disrupts murine embryogenesis with relevance to human birth defects, http://dx.doi.org/10.1101/2024.05.07.592899

Marjaneh M; Kirk EP; Patrick R; Alankerage D; Humphreys DT; Del Monte-Nieto G; Cornejo-Paramo P; Janbandhu V; Doan TB; Dunwoodie SL; Wong ES; Moran C; Martin ICA; Thomson PC; Harvey RP, Quantitative trait and transcriptome analysis of genetic complexity underpinning cardiac interatrial septation in mice using an advanced intercross line, http://dx.doi.org/10.1101/2022.10.31.514499

Humphreys DT; Lewis A; Pan-Castillo B; Berti G; Mein C; Wozniak E; Gordon H; Gadhok R; Minicozzi A; ChinAleong J; Feakins R; Giannoulatou E; James LK; Stagg AJ; Lindsay JO; Silver A, Single cell sequencing data identify distinct B cell and fibroblast populations in stricturing Crohn’s disease, http://dx.doi.org/10.1101/2023.09.04.556163

Nicks AM; Holman SR; Chan AY; Tsang M; Young PE; Humphreys DT; Naqvi N; Husain A; Li M; Smith NJ; Iismaa SE; Graham RM, Standardised method for cardiomyocyte isolation and purification from individual murine neonatal, infant, and adult hearts, http://dx.doi.org/10.1101/2021.09.30.462562

Ridone P; Ishida T; Lin A; Humphreys DT; Giannoulatou E; Sowa Y; Baker MAB, The rapid evolution of flagellar ion-selectivity in experimental populations of E. coli, http://dx.doi.org/10.1101/2021.01.26.427765

Humphreys DT; Fossat N; Tam PPL; Ho JWK, Ularcirc: Visualisation and enhanced analysis of circular RNAs via back and canonical forward splicing, http://dx.doi.org/10.1101/318436

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