By Dr David Robert Croucher

Journal articles

Pereira BA; Ritchie S; Chambers CR; Gordon KA; Magenau A; Murphy KJ; Nobis M; Tyma VM; Liew YF; Lucas MC; Naeini MM; Barkauskas DS; Chacon-Fajardo D; Howell AE; Parker AL; Warren SC; Reed DA; Lee V; Metcalf XL; Lee YK; O'Regan LP; Zhu J; Trpceski M; Fontaine ARM; Stoehr J; Rouet R; Lin X; Chitty JL; Porazinski S; Wu SZ; Filipe EC; Cadell AL; Holliday H; Yang J; Papanicolaou M; Lyons RJ; Zaratzian A; Tayao M; Da Silva A; Vennin C; Yin J; Dew AB; McMillan PJ; Goldstein LD; Deveson IW; Croucher DR; Samuel MS; Sim HW; Batten M; Chantrill L; Grimmond SM; Gill AJ; Samra J; Jeffry Evans TR; Sasaki T; Phan TG; Swarbrick A; Sansom OJ; Morton JP; Pajic M; Parker BL; Herrmann D; Cox TR; Timpson P, 2024, 'Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response', Science Advances, 10, http://dx.doi.org/10.1126/sciadv.adl1197

Filipe EC; Velayuthar S; Philp A; Nobis M; Latham SL; Parker AL; Murphy KJ; Wyllie K; Major GS; Contreras O; Mok ETY; Enriquez RF; McGowan S; Feher K; Quek LE; Hancock SE; Yam M; Tran E; Setargew YFI; Skhinas JN; Chitty JL; Phimmachanh M; Han JZR; Cadell AL; Papanicolaou M; Mahmodi H; Kiedik B; Junankar S; Ross SE; Lam N; Coulson R; Yang J; Zaratzian A; Da Silva AM; Tayao M; Chin IL; Cazet A; Kansara M; Segara D; Parker A; Hoy AJ; Harvey RP; Bogdanovic O; Timpson P; Croucher DR; Lim E; Swarbrick A; Holst J; Turner N; Choi YS; Kabakova IV; Philp A; Cox TR, 2024, 'Tumor Biomechanics Alters Metastatic Dissemination of Triple Negative Breast Cancer via Rewiring Fatty Acid Metabolism', Advanced Science, 11, http://dx.doi.org/10.1002/advs.202307963

Chitty JL; Yam M; Perryman L; Parker AL; Skhinas JN; Setargew YFI; Mok ETY; Tran E; Grant RD; Latham SL; Pereira BA; Ritchie SC; Murphy KJ; Trpceski M; Findlay AD; Melenec P; Filipe EC; Nadalini A; Velayuthar S; Major G; Wyllie K; Papanicolaou M; Ratnaseelan S; Phillips PA; Sharbeen G; Youkhana J; Russo A; Blackwell A; Hastings JF; Lucas MC; Chambers CR; Reed DA; Stoehr J; Vennin C; Pidsley R; Zaratzian A; Da Silva AM; Tayao M; Charlton B; Herrmann D; Nobis M; Clark SJ; Biankin AV; Johns AL; Croucher DR; Nagrial A; Gill AJ; Grimmond SM; Chantrill LA; Chou A; Dwarte T; Metcalf XL; Jeong G; Kenyon L; Waddell N; Pearson JV; Patch AM; Nones K; Newell F; Mukhopadhyay P; Addala V; Kazakoff S; Holmes O; Leonard C; Wood S; Hofmann O; Samra JS; Pavlakis N; Arena J; High HA; Asghari R; Merrett ND; Das A; Cosman PH; Ismail K; Stoita A; Williams D; Spigellman A; McLeo D; Kirk J; Kench JG; Grimison P; Sandroussi C; Goodwin A; Mead RS; Tucker K; Andrews L; Texler M; Forrest C; Ballal M; Fletcher D; Beilin M; Feeney K; Epari K; Mukhedkar S; Zeps N; Nguyen NQ; Ruszkiewicz AR; Worthley C; Chen J, 2023, 'A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer', Nature Cancer, 4, pp. 1326 - 1344, http://dx.doi.org/10.1038/s43018-023-00614-y

Nguyen T; Lau A; Bier J; Cooke KC; Lenthall H; Ruiz-Diaz S; Avery DT; Brigden H; Zahra D; Sewell WA; Droney L; Okada S; Asano T; Abolhassani H; Chavoshzadeh Z; Abraham RS; Rajapakse N; Klee EW; Church JA; Williams A; Wong M; Burkhart C; Uzel G; Croucher DR; James DE; Ma CS; Brink R; Tangye SG; Deenick EK, 2023, 'Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2', The Journal of experimental medicine, 220, http://dx.doi.org/10.1084/jem.20221020

Conway JRW; Warren SC; Lee YK; McCulloch AT; Magenau A; Lee V; Metcalf XL; Stoehr J; Haigh K; Abdulkhalek L; Guaman CS; Reed DA; Murphy KJ; Pereira BA; Mélénec P; Chambers C; Latham SL; Lenthall H; Deenick EK; Ma Y; Phan T; Lim E; Joshua AM; Walters S; Grey ST; Shi YC; Zhang L; Herzog H; Croucher DR; Philp A; Scheele CLGJ; Herrmann D; Sansom OJ; Morton JP; Papa A; Haigh JJ; Nobis M; Timpson P, 2023, 'Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse', Science Advances, 9, http://dx.doi.org/10.1126/sciadv.adf9063

Hastings JF; Latham SL; Kamili A; Wheatley MS; Han JZR; Wong-Erasmus M; Phimmachanh M; Nobis M; Pantarelli C; Cadell AL; O’Donnell YEI; Leong KH; Lynn S; Geng FS; Cui L; Yan S; Achinger-Kawecka J; Stirzaker C; Norris MD; Haber M; Trahair TN; Speleman F; De Preter K; Cowley MJ; Bogdanovic O; Timpson P; Cox TR; Kolch W; Fletcher JI; Fey D; Croucher DR, 2023, 'Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma', Science Advances, 9, http://dx.doi.org/10.1126/sciadv.abp8314

Walter S; Ho J; Alvarado R; Smith G; Croucher DR; Liang S; Grayson JW; Mangussi-Gomes J; Van Es SL; Earls P; Rimmer J; Campbell R; Kalish L; Sacks R; Harvey RJ, 2022, 'Mepolizumab decreases tissue eosinophils while increasing type-2 cytokines in eosinophilic chronic rhinosinusitis', Clinical and Experimental Allergy, 52, pp. 1403 - 1413, http://dx.doi.org/10.1111/cea.14152

Latham SL; O'Donnell YEI; Croucher DR, 2022, 'Non-kinase targeting of oncogenic c-Jun Nterminal kinase (JNK) signaling: the future of clinically viable cancer treatments', Biochemical Society Transactions, 50, pp. 1823 - 1836, http://dx.doi.org/10.1042/BST20220808

Papanicolaou M; Parker AL; Yam M; Filipe EC; Wu SZ; Chitty JL; Wyllie K; Tran E; Mok E; Nadalini A; Skhinas JN; Lucas MC; Herrmann D; Nobis M; Pereira BA; Law AMK; Castillo L; Murphy KJ; Zaratzian A; Hastings JF; Croucher DR; Lim E; Oliver BG; Mora FV; Parker BL; Gallego-Ortega D; Swarbrick A; O’Toole S; Timpson P; Cox TR, 2022, 'Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis', Nature Communications, 13, http://dx.doi.org/10.1038/s41467-022-32255-7

Raftopulos NL; Washaya TC; Niederprum A; Egert A; Hakeem-Sanni MF; Varney B; Aishah A; Georgieva ML; Olsson E; Dos Santos DZ; Nassar ZD; Cochran BJ; Nagarajan SR; Kakani MS; Hastings JF; Croucher DR; Rye K-A; Butler LM; Grewal T; Hoy AJ, 2022, 'Prostate cancer cell proliferation is influenced by LDL-cholesterol availability and cholesteryl ester turnover', CANCER & METABOLISM, 10, http://dx.doi.org/10.1186/s40170-021-00278-1

Munoz MA; Fletcher EK; Skinner OP; Jurczyluk J; Kristianto E; Hodson MP; Sun S; Ebetino FH; Croucher DR; Hansbro PM; Center JR; Rogers MJ, 2021, 'Bisphosphonate drugs have actions in the lung and inhibit the mevalonate pathway in alveolar macrophages', eLife, 10, http://dx.doi.org/10.7554/eLife.72430

Lin HM; Yeung N; Hastings JF; Croucher DR; Huynh K; Meikle TG; Mellett NA; Kwan EM; Davis ID; Tran B; Mahon KL; Zhang A; Stockler MR; Briscoe K; Marx G; Bastick P; Crumbaker ML; Joshua AM; Azad AA; Meikle PJ; Horvath LG, 2021, 'Relationship between circulating lipids and cytokines in metastatic castration‐resistant prostate cancer', Cancers, 13, http://dx.doi.org/10.3390/cancers13194964

Floerchinger A; Murphy KJ; Latham SL; Warren SC; McCulloch AT; Lee YK; Stoehr J; Mélénec P; Guaman CS; Metcalf XL; Lee V; Zaratzian A; Da Silva A; Tayao M; Rolo S; Phimmachanh M; Sultani G; McDonald L; Mason SM; Ferrari N; Ooms LM; Johnsson AKE; Spence HJ; Olson MF; Machesky LM; Sansom OJ; Morton JP; Mitchell CA; Samuel MS; Croucher DR; Welch HCE; Blyth K; Caldon CE; Herrmann D; Anderson KI; Timpson P; Nobis M, 2021, 'Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging', Cell Reports, 36, http://dx.doi.org/10.1016/j.celrep.2021.109689

Rajal AG; Marzec KA; McCloy RA; Nobis M; Chin V; Hastings JF; Lai K; Kennerson M; Hughes WE; Vaghjiani V; Timpson P; Cain JE; Watkins DN; Croucher DR; Burgess A, 2021, 'A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma', eLife, 10, http://dx.doi.org/10.7554/eLife.65234

Han JZR; Hastings JF; Phimmachanh M; Fey D; Kolch W; Croucher DR, 2021, 'Personalized medicine for neuroblastoma: Moving from static genotypes to dynamic simulations of drug response', Journal of Personalized Medicine, 11, http://dx.doi.org/10.3390/jpm11050395

Munoz M; Fletcher E; Skinner O; Jurczyluk J; Kristianto E; Hodson M; Sun S; Ebetino F; Croucher D; Hansbro P; Center J; Rogers M, 2021, 'Bisphosphonate drugs have actions outside the skeleton and inhibit the mevalonate pathway in alveolar macrophages', , http://dx.doi.org/10.1101/2021.08.09.455652

Cultrone D; Zammit NW; Self E; Postert B; Han JZR; Bailey J; Warren J; Croucher DR; Kikuchi K; Bogdanovic O; Chtanova T; Hesselson D; Grey ST, 2020, 'A zebrafish functional genomics model to investigate the role of human A20 variants in vivo', Scientific Reports, 10, http://dx.doi.org/10.1038/s41598-020-75917-6

Phimmachanh M; Han JZR; O’Donnell YEI; Latham SL; Croucher DR, 2020, 'Histone Deacetylases and Histone Deacetylase Inhibitors in Neuroblastoma', Frontiers in Cell and Developmental Biology, 8, http://dx.doi.org/10.3389/fcell.2020.578770

Filipčík P; Latham SL; Cadell AL; Day CL; Croucher DR; Mace PD, 2020, 'A cryptic tubulin-binding domain links MEKK1 to curved tubulin protomers', Proceedings of the National Academy of Sciences of the United States of America, 117, pp. 21308 - 21318, http://dx.doi.org/10.1073/pnas.2006429117

Latham SL; Weiß N; Schwanke K; Thiel C; Croucher DR; Zweigerdt R; Manstein DJ; Taft MH, 2020, 'Myosin-18B Regulates Higher-Order Organization of the Cardiac Sarcomere through Thin Filament Cross-Linking and Thick Filament Dynamics', Cell Reports, 32, http://dx.doi.org/10.1016/j.celrep.2020.108090

Hastings JF; O'Donnell YEI; Fey D; Croucher DR, 2020, 'Applications of personalised signalling network models in precision oncology', Pharmacology and Therapeutics, 212, http://dx.doi.org/10.1016/j.pharmthera.2020.107555

Hastings JF; Rajal AG; Latham SL; Han JZR; McCloy RA; O’donnell YEI; Phimmachanh M; Murphy AD; Nagrial A; Daneshvar D; Chin V; Watkins DN; Burgess A; Croucher DR, 2020, 'Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma', eLife, 9, pp. 1 - 25, http://dx.doi.org/10.7554/eLife.53367

Gonzalez-Rajal A; Hastings JF; Watkins DN; Croucher DR; Burgess A, 2020, 'Breathing New Life into the Mechanisms of Platinum Resistance in Lung Adenocarcinoma', Frontiers in Cell and Developmental Biology, 8, http://dx.doi.org/10.3389/fcell.2020.00305

Cipponi A; Goode DL; Bedo J; McCabe MJ; Pajic M; Croucher DR; Rajal AG; Junankar SR; Saunders DN; Lobachevsky P; Papenfuss AT; Nessem D; Nobis M; Warren SC; Timpson P; Cowley M; Vargas AC; Qiu MR; Generali DG; Keerthikumar S; Nguyen U; Corcoran NM; Long GV; Blay J-Y; Thomas DM; McCabe M, 2020, 'MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer', Science

Trevelyan SJ; Brewster JL; Burgess AE; Crowther JM; Cadell AL; Parker BL; Croucher DR; Dobson RCJ; Murphy JM; Mace PD, 2020, 'Structure-based mechanism of preferential complex formation by apoptosis signal–regulating kinases', Science Signaling, 13, http://dx.doi.org/10.1126/scisignal.aay6318

Filipčík P; Latham S; Cadell A; Day C; Croucher D; Mace P, 2020, 'A cryptic tubulin-binding domain links MEKK1 to microtubule remodelling', , http://dx.doi.org/10.1101/2020.04.07.030676

Gonzalez-Rajal A; Marzec K; McCloy R; Nobis M; Chin V; Hastings J; Lai K; Kennerson M; Hughes W; Vaghjiani V; Timpson P; Cain J; Neil Watkins D; Croucher D; Burgess A, 2020, 'A Non-Genetic, Cell Cycle Dependent Mechanism of Platinum Resistance in Lung Adenocarcinoma', , http://dx.doi.org/10.1101/2020.11.26.400499

Cultrone D; Zammit N; Self E; Postert B; Han JZR; Bailey J; Warren J; Croucher D; Kikuchi K; Bogdanovic O; Chtanova T; Hesselson D; Grey S, 2020, 'A zebrafish functional genomics model to investigate the role of human A20 variantsin vivo', , http://dx.doi.org/10.1101/2020.02.23.961763

Vennin C; Mélénec P; Rouet R; Nobis M; Cazet AS; Murphy KJ; Herrmann D; Reed DA; Lucas MC; Warren SC; Elgundi Z; Pinese M; Kalna G; Roden D; Samuel M; Zaratzian A; Grey ST; Da Silva A; Leung W; Johns AL; Chantrill LA; Chou A; Steinmann A; Arshi M; Dwarte T; Froio D; Pereira B; Ritchie S; Chambers CR; Metcalf X; Waddell N; Pearson JV; Patch AM; Nones K; Newell F; Mukhopadhyay P; Addala V; Kazakoff S; Holmes O; Leonard C; Wood S; Grimmond SM; Hofmann O; Christ A; Bruxner T; Samra JS; Pavlakis N; High HA; Asghari R; Merrett ND; Pavey D; Das A; Cosman PH; Ismail K; O’Connnor C; Stoita A; Williams D; Spigellman A; Lam VW; McLeod D; Kirk J; Kench JG; Grimison P; Cooper CL; Sandroussi C; Goodwin A; Mead RS; Tucker K; Andrews L; Texler M; Forest C; Epari KP; Ballal M; Fletcher DR; Mukhedkar S; Zeps N; Beilin M; Feeney K; Nguyen NQ; Ruszkiewicz AR; Worthley C; Chen J; Brooke-Smith ME; Papangelis V; Clouston AD; Barbour AP; O’Rourke TJ; Fawcett JW; Slater K; Hatzifotis M; Hodgkinson P; Nikfarjam M; Eshleman JR; Hruban RH; Wolfgang CL; Lawlor RT; Beghelli S; Corbo V; Scardoni M; Bassi C; Christ D; Cox T; Timpson P; Phillips P; Whitelock J; Pajic M; Gill A; Croucher D, 2019, 'CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan', Nature Communications, 10, pp. 3637, http://dx.doi.org/10.1038/s41467-019-10968-6

Castillo L; George S; Lin H-M; Yeung N; Mawson A; Young AI; Law AM; Hastings J; Gallego-Ortega D; Deng N; Croucher D; Swarbrick A; Horvath L; Ormandy CJ; Oakes SR, 2019, 'Flicking the switch off, targeting MCL-1 in the treatment of breast and prostate cancer', Oncology Abstracts, http://dx.doi.org/10.1530/oncolabs.1.p038

Kennedy SP; Han JZR; Portman N; Nobis M; Hastings JF; Murphy KJ; Latham SL; Cadell AL; Miladinovic D; Marriott GR; O'Donnell YEI; Shearer RF; Williams JT; Munoz AG; Cox TR; Watkins DN; Saunders DN; Timpson P; Lim E; Kolch W; Croucher DR, 2019, 'Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer', Breast Cancer Research, 21, http://dx.doi.org/10.1186/s13058-019-1127-y

Hastings JF; Skhinas JN; Fey D; Croucher DR; Cox TR, 2019, 'The extracellular matrix as a key regulator of intracellular signalling networks', British Journal of Pharmacology, 176, pp. 82 - 92, http://dx.doi.org/10.1111/bph.14195

Rogers S; McCloy RA; Parker BL; Gallego-Ortega D; Law AMK; Chin VT; Conway JRW; Fey D; Millar EKA; O’Toole S; Deng N; Swarbrick A; Chastain PD; Cesare AJ; Timpson P; Caldon CE; Croucher DR; James DE; Watkins DN; Burgess A, 2018, 'MASTL overexpression promotes chromosome instability and metastasis in breast cancer', Oncogene, 37, pp. 4518 - 4533, http://dx.doi.org/10.1038/s41388-018-0295-z

Marini KD; Croucher DR; McCloy RA; Vaghjiani V; Gonzalez-Rajal A; Hastings JF; Chin V; Szczepny A; Kostyrko K; Marquez C; Samantha W; Jayasekara N; Alamgeer M; Boolell V; Han JZR; Waugh T; Lee HC; Oakes SR; Kumar B; Harrison CA; Hedger MP; Lorensuhewa N; Kita B; Barrow R; Robinson BW; De Kretser DM; Wu J; Ganju V; Alejandro Sweet-Cordero E; Burgess A; Martelotto LG; Rossello FJ; Cain JE; Neil Watkins D, 2018, 'Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapy', Science Translational Medicine, 10, http://dx.doi.org/10.1126/scitranslmed.aat3504

Hastings JF; Han JZR; Shearer RF; Kennedy SP; Iconomou M; Saunders DN; Croucher DR, 2018, 'Dissecting multi-protein signaling complexes by bimolecular complementation affinity purification (Bicap)', Journal of Visualized Experiments, 2018, http://dx.doi.org/10.3791/57109

Hastings JF; Han JZR; Shearer RF; Kennedy SP; Iconomou M; Saunders DN; Croucher DR, 2018, 'Dissecting Multi-protein Signaling Complexes by Bimolecular Complementation Affinity Purification (BiCAP)', Journal of Visualized Experiments, http://dx.doi.org/10.3791/57109-v

Conway JRW; Warren SC; Herrmann D; Murphy KJ; Cazet AS; Vennin C; Shearer RF; Killen MJ; Magenau A; Mélénec P; Pinese M; Nobis M; Zaratzian A; Boulghourjian A; Da Silva AM; del Monte-Nieto G; Adam ASA; Harvey RP; Haigh JJ; Wang Y; Croucher DR; Sansom OJ; Pajic M; Caldon CE; Morton JP; Timpson P; del Monte Nieto G; Gallego-Ortega D, 2018, 'Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer', Cell Reports, 23, pp. 3312 - 3326, http://dx.doi.org/10.1016/j.celrep.2018.05.038

Vouri M; Croucher DR; Kennedy SP; An Q; Pilkington GJ; Hafizi S, 2016, 'Axl-EGFR receptor tyrosine kinase hetero-interaction provides EGFR with access to pro-invasive signalling in cancer cells', Oncogenesis, 5, pp. e266 - e266, http://dx.doi.org/10.1038/oncsis.2016.66

Kennedy SP; Hastings JF; Han JZR; Croucher DR, 2016, 'The under-appreciated promiscuity of the epidermal growth factor receptor family', Frontiers in Cell and Developmental Biology, 4, http://dx.doi.org/10.3389/fcell.2016.00088

Croucher DR; Iconomou M; Hastings JF; Kennedy SP; Shearer RF; McKenna J; Wan A; Lau J; Aparicio S; Saunders DN, 2016, 'Bimolecular complementation affinity purification (BiCAP) reveals dimer-specific protein interactions for ERBB2 dimers', Science Signaling, 9, pp. ra69 - ra69, http://dx.doi.org/10.1126/scisignal.aaf0793

Rogers S; Fey D; McCloy RA; Parker BL; Mitchell NJ; Payne RJ; Daly RJ; James DE; Caldon CE; Watkins DN; Croucher DR; Burgess A, 2016, 'PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells', Journal of Cell Science, 129, pp. 1340 - 1354, http://dx.doi.org/10.1242/jcs.179754

Erami Z; Herrmann D; Warren SC; Nobis M; McGhee EJ; Lucas MC; Leung W; Reischmann N; Mrowinska A; Schwarz JP; Kadir S; Conway JRW; Vennin C; Karim SA; Campbell AD; Gallego-Ortega D; Magenau A; Murphy KJ; Ridgway RA; Law AM; Walters SN; Grey ST; Croucher DR; Zhang L; Herzog H; Hardeman EC; Gunning PW; Ormandy CJ; Evans TRJ; Strathdee D; Sansom OJ; Morton JP; Anderson KI; Timpson P; Zhang L, 2016, 'Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue', Cell Reports, 14, pp. 152 - 167, http://dx.doi.org/10.1016/j.celrep.2015.12.020

Saunders DN; Croucher D, 2016, 'Dissecting and Deconvoluting Multi-molecular Complexes - Principles of Systems Biology, No. 7', Cell Systems, 3, pp. 3 - 6, http://dx.doi.org/10.1016/j.cels.2016.07.010

Fey D; Halasz M; Dreidax D; Kennedy SP; Hastings JF; Rauch N; Munoz AG; Pilkington R; Fischer M; Westermann F; Kolch W; Kholodenko BN; Croucher DR, 2015, 'Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients', Science Signaling, 8, http://dx.doi.org/10.1126/scisignal.aab0990

Freeman R; Niego B; Croucher DR; Pedersen LO; Medcalf RL, 2014, 'T-PA, but not desmoteplase, induces plasmin-dependent opening of a blood-brain barrier model under normoxic and ischaemic conditions', Brain Research, 1565, pp. 63 - 73, http://dx.doi.org/10.1016/j.brainres.2014.03.027

Duffy FJ; Devocelle M; Croucher DR; Shields DC, 2014, 'Computational survey of peptides derived from disulphide-bonded protein loops that may serve as mediators of protein-protein interactions', BMC Bioinformatics, 15, http://dx.doi.org/10.1186/1471-2105-15-305

Zheng Y; Zhang C; Croucher DR; Soliman MA; St-Denis N; Pasculescu A; Taylor L; Tate SA; Rod Hardy W; Colwill K; Dai AY; Bagshaw R; Dennis JW; Gingras AC; Daly RJ; Pawson T, 2013, 'Temporal regulation of EGF signalling networks by the scaffold protein Shc1', Nature, 499, pp. 166 - 171, http://dx.doi.org/10.1038/nature12308

Croucher DR; Hochgräfe F; Zhang L; Liu L; Lyons RJ; Rickwood D; Tactacan CM; Browne BC; Ali N; Chan H; Shearer R; Gallego-Ortega D; Saunders DN; Swarbrick A; Daly RJ, 2013, 'Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway', Cancer Research, 73, pp. 1969 - 1980, http://dx.doi.org/10.1158/0008-5472.CAN-12-1472

Nguyen LK; Matallanas D; Croucher DR; Von Kriegsheim A; Kholodenko BN, 2013, 'Signalling by protein phosphatases and drug development: A systems-centred view', FEBS Journal, 280, pp. 751 - 765, http://dx.doi.org/10.1111/j.1742-4658.2012.08522.x

Ortiz-padilla C; Gallego-ortega D; Browne B; Hochgrafe F; Caldon CE; Lyons R; Croucher DR; Rickwood D; Ormandy CJ; Brummer T; Daly RJ, 2013, 'Functional characterization of cancer-associated Gab1 mutations', Oncogene, 32, pp. 2696 - 2702, http://dx.doi.org/10.1038/onc.2012.271

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