By Dr Emmy Dorothee Grace Fleuren

Conference Papers

Volken L; Tax G; Mao J; Cadiz R; Rishfi M; Dolman E; Fleuren E, 2024, 'Advancing precision medicine in paediatric sarcoma: Harnessing DNA damage response pathway for targeted therapies.', Sydney, presented at ZERO Childhood Cancer National Symposium 2024, Sydney, 08 May 2024

Perkins C; Barger Z; Fordham A; Salib A; Lim Kam Sian T; Daly R; Ekert P; Fleuren E, 2024, 'Phosphoproteomic profiling for novel target identification in childhood sarcomas: Paving the road towards improved outcomes for relapsed and metastatic osteosarcoma', Sydney, Australia, presented at ZERO Childhood Cancer National Symposium “Precision in Action: Collaboration Driving Cancer Breakthroughs”, Sydney, Australia, 08 May 2024

Barger Z; Fordham A; Mao J; Brown L; Perkins C; Gunther K; Paul E; Fleuren E, 2024, 'ZERO and beyond: Establishment, Characterisation, and Utilisation of Nine Novel Patient-Derived Osteosarcoma Cell Lines', Sydney, Australia, presented at ZERO Childhood Cancer National Symposium “Precision in Action: Collaboration Driving Cancer Breakthroughs", Sydney, Australia, 08 May 2024

Volken L; Tax G; Mao J; Cadiz R; Rishfi M; Dolman E; Fleuren E, 2024, 'Exploiting the dna damage response to develop personalised treatments for high-risk sarcoma in children', Lorne, presented at Lorne Cancer, Lorne, 09 February 2024, https://cancer-2024.p.asnevents.com.au/days/2024-02-09/abstract/100289

Perkins C; Barger Z; Fordham A; Salib A; Lim Kam Sian T; Daly R; Ekert P; Fleuren E, 2024, 'Phosphoproteomic profiling for novel target identification in childhood sarcomas: Paving the road towards improved outcomes for relapsed and metastatic osteosarcoma.', Lorne, presented at Lorne Cancer, Lorne, 09 February 2024, https://cancer-2024.p.asnevents.com.au/days/2024-02-09/abstract/100264

Perkins C; Barger Z; Fordham A; Salib A; Lim Kam Sian T; Daly R; Ekert P; Fleuren E, 2023, 'Phosphoproteomic profiling for novel target identification in childhood sarcomas: Paving the road towards improved outcomes for relapsed and metastatic osteosarcoma', Sydney, presented at Children’s Cancer Institute - Research Symposium, Sydney, 04 December 2023

Barger Z; Fordham A; Mao J; Brown L; Perkins C; Gunther K; Ekert P; Fleuren E, 2023, 'Advancing Preclinical Sarcoma Models: The Establishment and Characterisation of Nine Novel Patient-Derived Osteosarcoma Cell Lines', Melbourne, presented at Australia and New Zealand Sarcoma Association (ANZSA) Annual Scientific Meeting, Melbourne, 10 November 2023

Perkins C; Barger Z; Fordham A; Salib A; Lim Kam Sian T; Daly R; Ekert P; Fleuren E, 2023, 'Phosphoproteomic profiling for novel target identification in childhood sarcomas: Paving the road towards improved outcomes for relapsed and metastatic osteosarcoma', Melbourne, presented at Australia and New Zealand Sarcoma Association (ANZSA) Annual Meeting, Melbourne, 10 November 2023

Perkins C; Barger Z; Fordham A; Salib A; Lim Kam Sian T; Daly R; Ekert P; Fleuren E, 2023, 'Phosphoproteomic profiling for novel target identification in childhood sarcomas: Paving the road towards improved outcomes for relapsed and metastatic osteosarcoma.', Cape Schanck/Melbourne, presented at Cell Signalling and its Therapeutic Implications (CSTI) 2023, Cape Schanck/Melbourne, 16 May 2023, https://drive.google.com/file/d/1G0HeWsknc2z2W3Tq0rTQkECg4SLzgTsO/view

Perkins C; Barger Z; Fordham A; Salib A; Lim Kam Sian T; Daly R; Ekert P; Fleuren E, 2023, 'Phosphoproteomic profiling for novel target identification in childhood sarcomas: Paving the road towards improved outcomes for relapsed and metastatic osteosarcoma', Melbourne (Cape Schanck), presented at Cell Signalling and its Therapeutic Implications (CSTI 2023), Melbourne (Cape Schanck), 15 May 2023, https://drive.google.com/file/d/1G0HeWsknc2z2W3Tq0rTQkECg4SLzgTsO/view

Xie J; Gifford A; Mao J; Cadiz R; Avila A; Yun DY; Zhou A; Dolman E; Fleuren E; Mayoh C; Barahona P; Lau L; Kamili A; Tsoli M; Marshall G; Ziegler D; Trahair T; Haber M; Tyrrell V; Lock R, 2022, 'Establishment and application of patient-derived xenograft models for personalised medicine in paediatric cancer', Sydney, presented at Children’s Cancer Institute - Research Symposium 2022, Sydney, 06 December 2022

Barger Z; Fordham A; Perkins C; Gunther K; Ekert P; Fleuren E, 2022, 'Optimisation of functional in vitro patient-derived osteosarcoma cell culture models', Sydney, presented at Children’s Cancer Institute - Research Symposium 2022, Sydney, 06 December 2022

Fordham A; Brown L; Mayoh C; Wong M; Barger Z; O'Regan L; Lim Kan Siam T; Xie J; Gunther K; Barahona P; Ajuyah P; Lau L; Ziegler D; Haber M; Tyrrell V; Lock R; Cowley M; Nicholls W; Daly R; Ekert P; Fleuren E, 2022, 'MULTI-PLATFORM TYROSINE KINASE PROFILING REVEALS NOVEL ACTIONABLE FGFR ABERRATIONS ACROSS PEDIATRIC AND ADOLESCENT AND YOUNG ADULT SARCOMAS', Vancouver, Canada, presented at Connective Tissue Oncology Society (CTOS) Annual Meeting 2022, Vancouver, Canada, 17 November 2022

Barger Z; Fordham A; Perkins C; Gunther K; Ekert P; Fleuren E, 2022, 'Optimisation of functional in vitro patient-derived osteosarcoma cell culture models.', Sydney, presented at ZERO Childhood Cancer National Symposium “Towards Precision Oncology for All” 2022, Sydney, 26 October 2022

Fordham A; Brown L; Mayoh C; Wong M; Barger Z; Xie J; Gunther K; Trebilcock P; Lock R; Cowley M; Ekert P; Fleuren E, 2021, 'Multi-platform tyrosine kinase profiling reveals novel molecular response signatures to FGFR-inhibitors in paediatric and AYA sarcoma', Sydney (virtual), presented at Kids Cancer Alliance (KCA) Symposium 2021, Sydney (virtual), 02 September 2021

Fleuren E; Dolman E; Lau L; Xie J; Batey D; Mayoh C; Barahona P; Khuong Quang DA; Wong M; ZERO PDTT; ZERO OT; Norris M; Haber M; Trahair T; Marshall G; Ziegler D; Tyrrell V; Cowley M; Lock R; Ekert P, 2021, 'Supporting clinical decision-making for PI3K/AKT/mTOR inhibitors for high-risk paediatric and adolescent and young adult (AYA) sarcoma', Virtual, presented at The Australian and New Zealand Children’s Haematology/Oncology Group (ANZCHOG) Annual Scientific Meeting, Virtual, 24 June 2021

Fordham A; Brown L; Mayoh C; Wong M; Barger Z; Xie J; Gunther K; Trebilcock P; Lim Kam Sian T; Lock R; Daly R; Cowley M; Ekert P; Fleuren E, 2021, 'Multi-platform tyrosine kinase profiling reveals novel molecular response signatures to FGFR-inhibitors in paediatric and AYA sarcoma.', Virtual, presented at The Australian Society for Medical Research (ASMR) 2021, Virtual, 10 June 2021

Fleuren E; Dolman E; Lau L; Xie J; Batey D; Mayoh C; Barahona P; Sherstyuk A; Khuong Quang DA; Wong M; ZERO PDTT; ZERO OT; Thomas D; Mould E; Norris M; Haber M; Trahair T; Marshall G; Ziegler D; Tyrrell V; Cowley M; Lock R; Ekert P, 2020, 'Supporting clinical decision-making for PI3K/AKT/MTOR inhibitors for high-risk paediatric and AYA sarcoma', Virtual, presented at Connective Tissue Oncology Society (CTOS) Annual Meeting 2020, Virtual, 18 November 2020

Fleuren E; Dolman E; Lau L; Xie J; Batey D; Mayoh C; Barahona P; Khuong Quang DA; Wong M; ZERO PDTT; ZERO OT; Norris M; Haber M; Trahair T; Marshall G; Ziegler D; Tyrrell V; Cowley M; Lock R; Ekert P, 2020, 'Supporting clinical decision-making for PI3K/AKT/MTOR inhibitors for high-risk paediatric sarcoma patients', Virtual, presented at KCA Symposium 2020, Virtual, 17 September 2020

Fleuren E; Lau L; Barahona P; Sherstyuk A; Mayoh C; Terry R; Khuong Quang DA; Wong M; Xie J; Batey D; Grebert-Wade D; Strong P; Lim JY; Chow S-O; Kumar A; Failes T; Arndt G; Mould E; Haber M; Norris M; Lock R; Trahair T; Marshall G; Ziegler D; Tyrrell V; Cowley M; Ekert P, 2020, 'Precision medicine for high-risk paediatric and AYA sarcomas', Lorne, presented at Lorne Cancer 2020, Lorne, 13 February 2020

Fleuren E; Xie J; Barahona P; Sherstyuk A; Batey D; Jin Yi L; Lau L; Khuong Quang DA; Failes T; Chow S-O; Mayoh C; Wong M; Kumar A; ZERO OT; ZERO PDTT; ZERO SMT; Thomas D; Trahair T; Haber M; Mould E; Lock R; Ziegler D; Tyrrell V; Cowley M; Ekert P, 2019, 'Personalised medicine for high-risk paediatric and AYA sarcoma patients', Tokyo, Japan, presented at Connective Tissue Oncology Society (CTOS) Annual Meeting, Tokyo, Japan, 13 November 2019, https://www.ctos.org/Portals/0/PDF/2019%20CTOS%20Final%20Program.pdf

Fleuren E; Lau L; Barahona P; Sherstyuk A; Mayoh C; Khuong Quang DA; Wong M; Xie J; Batey D; Grebert-Wade D; Strong P; Lim JL; Chow S-O; Kumar A; Failes T; Arndt G; Mould E; Haber M; Lock R; Trahair T; Marshall G; Ziegler D; Tyrrell V; Cowley M; Ekert P, 2019, 'Precision medicine for high-risk paediatric and AYA sarcomas', Sydney, presented at Kids Cancer Alliance - Annual Meeting, Sydney, 31 October 2019, https://kca.org.au/wp-content/uploads/2019/11/2019-ECR-and-Student-Event-Program.pdf

Fleuren EDG; Jones S; Frankum J; Williamson C; Menon M; Shipley J; Ashworth A; van der Graaf W; Lord CJ, 2018, 'Synthetic lethality in synovial sarcoma: SS18-SSX fusions and DNA damage response (DDR) inhibitors', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, IL, Chicago, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), IL, Chicago, 14 April 2018 - 18 April 2018, http://dx.doi.org/10.1158/1538-7445.AM2018-2975

Fleuren ED; Vlenterie M; van der Graaf W; Hillebrandt-Roeffen M; Cebeci S; van de Ven A; Flucke U; Wu J; Versleijen-Jonkers Y; Daly R, 2017, 'Phosphoproteomic landscape of sarcoma: novel subgroups and actionable targets', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), DC, Washington, 01 April 2017 - 05 April 2017, http://dx.doi.org/10.1158/1538-7445.AM2017-5837

Fleuren EDG; Versleijen-Jonkers YMH; Roeffen MHS; Franssen GM; Houghton PJ; Oyen WJG; Boerman OC; van der Graaf WTA, 2013, 'Abstract 2761: Temsirolimus is effective as a single agent and in combination with cisplatin or bevacizumab in preclinical osteosarcoma models.', in Cancer Research, American Association for Cancer Research (AACR), pp. 2761 - 2761, http://dx.doi.org/10.1158/1538-7445.am2013-2761

Fleuren EDG; Versleijen-Jonkers YMH; van de Luijtgaarden ACM; Molkenboer-Kuenen JDM; Roeffen MHS; van Laarhoven HWM; Boerman OC; Oyen WJG; van der Graaf WTA, 2011, 'Abstract 5283: MicroSPECT imaging of IGF1R expression with radiolabeled R1507 in osteosarcoma models', in Cancer Research, American Association for Cancer Research (AACR), pp. 5283 - 5283, http://dx.doi.org/10.1158/1538-7445.am2011-5283

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