By Dr Ernest Moles Meler

Journal articles

Moles E; Chang DW; Mansfeld FM; Duly A; Kimpton K; Logan A; Howard CB; Thurecht KJ; Kavallaris M, 2024, 'EGFR Targeting of Liposomal Doxorubicin Improves Recognition and Suppression of Non-Small Cell Lung Cancer', International Journal of Nanomedicine, 19, pp. 3623 - 3639, http://dx.doi.org/10.2147/IJN.S450534

Moles E; Howard CB; Huda P; Karsa M; McCalmont H; Kimpton K; Duly A; Chen Y; Huang Y; Tursky ML; Ma D; Bustamante S; Pickford R; Connerty P; Omari S; Jolly CJ; Joshi S; Shen S; Pimanda JE; Dolnikov A; Cheung LC; Kotecha RS; Norris MD; Haber M; de Bock CE; Somers K; Lock RB; Thurecht KJ; Kavallaris M; Moles Meler E, 2023, 'Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia', Science translational medicine, 15, pp. eabm1262 - eabm1262, http://dx.doi.org/10.1126/scitranslmed.abm1262

Karsa M; Ronca E; Bongers A; Mariana A; Moles E; Failes TW; Arndt GM; Cheung LC; Kotecha RS; Kavallaris M; Haber M; Norris MD; Henderson MJ; Xiao L; Somers K; Moles Meler E, 2022, 'Systematic In Vitro Evaluation of a Library of Approved and Pharmacologically Active Compounds for the Identification of Novel Candidate Drugs for KMT2A-Rearranged Leukemia', Frontiers in Oncology, 11, pp. 779859, http://dx.doi.org/10.3389/fonc.2021.779859

Connerty P; Moles E; de Bock CE; Jayatilleke N; Smith JL; Meshinchi S; Mayoh C; Kavallaris M; Lock RB; Moles Meler E, 2021, 'Development of siRNA-loaded lipid nanoparticles targeting long non-coding RNA LINC01257 as a novel and safe therapeutic approach for t(8;21) pediatric acute myeloid leukemia', Pharmaceutics, 13, pp. 1681, http://dx.doi.org/10.3390/pharmaceutics13101681

Lantero E; Belavilas-Trovas A; Biosca A; Recolons P; Moles E; Sulleiro E; Zarzuela F; Ávalos-Padilla Y; Ramírez M; Fernàndez-Busquets X, 2020, 'Development of DNA Aptamers Against Plasmodium falciparum Blood Stages Using Cell-Systematic Evolution of Ligands by EXponential Enrichment', Journal of biomedical nanotechnology, 16, pp. 315 - 334, http://dx.doi.org/10.1166/jbn.2020.2901

Biosca A; Dirscherl L; Moles E; Imperial S; Fernàndez-Busquets X, 2019, 'An immunopegliposome for targeted antimalarial combination therapy at the nanoscale', Pharmaceutics, 11, http://dx.doi.org/10.3390/pharmaceutics11070341

Moles E; Kavallaris M, 2019, 'A potent targeted cancer nanotherapeutic', Nature Biomedical Engineering, 3, pp. 248 - 250, http://dx.doi.org/10.1038/s41551-019-0390-7

Moles E; Kavallaris M; Fernàndez-Busquets X, 2019, 'Modeling the distribution of diprotic basic drugs in liposomal systems: Perspectives on malaria nanotherapy', Frontiers in Pharmacology, 10, http://dx.doi.org/10.3389/fphar.2019.01064

Quiliano M; Pabón A; Moles E; Bonilla-Ramirez L; Fabing I; Fong KY; Nieto-Aco DA; Wright DW; Pizarro JC; Vettorazzi A; López de Cerain A; Deharo E; Fernández-Busquets X; Garavito G; Aldana I; Galiano S, 2018, 'Structure-activity relationship of new antimalarial 1-aryl-3-susbtituted propanol derivatives: Synthesis, preliminary toxicity profiling, parasite life cycle stage studies, target exploration, and targeted delivery', European Journal of Medicinal Chemistry, 152, pp. 489 - 514, http://dx.doi.org/10.1016/j.ejmech.2018.04.038

Moles E; Galiano S; Gomes A; Quiliano M; Teixeira C; Aldana I; Gomes P; Fernàndez-Busquets X, 2017, 'ImmunoPEGliposomes for the targeted delivery of novel lipophilic drugs to red blood cells in a falciparum malaria murine model', Biomaterials, 145, pp. 178 - 191, http://dx.doi.org/10.1016/j.biomaterials.2017.08.020

Moles E; Marcos J; Imperial S; Pozo OJ; Fernàndez-Busquets X, 2017, '2-picolylamine derivatization for high sensitivity detection of abscisic acid in apicomplexan blood-infecting parasites', Talanta, 168, pp. 130 - 135, http://dx.doi.org/10.1016/j.talanta.2017.03.030

Moles E; Moll K; Ch'ng JH; Parini P; Wahlgren M; Fernàndez-Busquets X, 2016, 'Development of drug-loaded immunoliposomes for the selective targeting and elimination of rosetting Plasmodium falciparum-infected red blood cells', Journal of Controlled Release, 241, pp. 57 - 67, http://dx.doi.org/10.1016/j.jconrel.2016.09.006

Ch'ng JH; Moll K; Quintana MDP; Chan SCL; Masters E; Moles E; Liu J; Eriksson AB; Wahlgren M, 2016, 'Rosette-Disrupting Effect of an Anti-Plasmodial Compound for the Potential Treatment of Plasmodium falciparum Malaria Complications', Scientific Reports, 6, http://dx.doi.org/10.1038/srep29317

Moles E; Valle-Delgado JJ; Urbán P; Azcárate IG; Bautista JM; Selva J; Egea G; Ventura S; Fernàndez-Busquets X, 2015, 'Possible roles of amyloids in malaria pathophysiology', Future Science OA, 1, http://dx.doi.org/10.4155/fso.15.43

Moles E; Urbán P; Jiménez-Díaz MB; Viera-Morilla S; Angulo-Barturen I; Busquets MA; Fernàndez-Busquets X, 2015, 'Immunoliposome-mediated drug delivery to Plasmodium-infected and non-infected red blood cells as a dual therapeutic/prophylactic antimalarial strategy', Journal of Controlled Release, 210, pp. 217 - 229, http://dx.doi.org/10.1016/j.jconrel.2015.05.284

Moles E; Fernandez-Busquets X, 2015, 'Loading antimalarial drugs into noninfected red blood cells: An undesirable roommate for Plasmodium', Future Medicinal Chemistry, 7, pp. 837 - 840, http://dx.doi.org/10.4155/fmc.15.35

Marques J; Moles E; Urbán P; Prohens R; Busquets MA; Sevrin C; Grandfils C; Fernàndez-Busquets X, 2014, 'Application of heparin as a dual agent with antimalarial and liposome targeting activities toward Plasmodium-infected red blood cells', Nanomedicine: Nanotechnology, Biology, and Medicine, 10, pp. 1719 - 1728, http://dx.doi.org/10.1016/j.nano.2014.06.002

Movellan J; Urbán P; Moles E; de la Fuente JM; Sierra T; Serrano JL; Fernàndez-Busquets X, 2014, 'Amphiphilic dendritic derivatives as nanocarriers for the targeted delivery of antimalarial drugs', Biomaterials, 35, pp. 7940 - 7950, http://dx.doi.org/10.1016/j.biomaterials.2014.05.061

Urbán P; Valle-Delgado JJ; Moles E; Marques J; Díez C; Fernàndez-Busquets X, 2012, 'Nanotools for the delivery of antimicrobial peptides', Current Drug Targets, 13, pp. 1158 - 1172, http://dx.doi.org/10.2174/138945012802002302

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