By Dr Fei Deng

Journal articles

Zhu T; Wang Z; Wu Y; Jiang W; Deng F; Fang R; Yang D, 2026, 'CIRCLE-F/V: a dual-mode CRISPR-Cas13a cascade biosensor for ultrasensitive and visual detection of low-abundance EGFR mutations', Journal of Biological Engineering, 20, pp. 74, http://dx.doi.org/10.1186/s13036-026-00675-4

Liu L; Zheng J; Lu X; Sarowar C; Wang Y; Smith MA; Wang X; Deng F; Mohanty B; Nor-Azman NA; Zhang F; Chiu SH; Torrado M; Li Y; Tang SY; Tang J; Spencer MJS; Kumar PV; Kalantar-Zadeh K; Zhang C, 2026, 'Gallium in liquid state shows nuclease-mimicking activity', Nature Communications, 17, pp. 5126, http://dx.doi.org/10.1038/s41467-026-71346-7

Wang R; Zhang Q; Gaira S; Zhao Y; Lai J; Li M; Zhang C; Wu L; Deng F; Tang SY, 2026, 'Artificial intelligence for CRISPR-based biosensing: From molecular design to assay intelligence', Trac Trends in Analytical Chemistry, 204, http://dx.doi.org/10.1016/j.trac.2026.119061

Zhou Y; Lu N; Hasan MW; Deng F; Fan J; Sang R; Chen W, 2026, 'Redox-responsive LNPs for therapeutics delivery', Advanced Drug Delivery Reviews, 237, http://dx.doi.org/10.1016/j.addr.2026.115934

Fu W; Sang R; Xue R; Bao G; Feng S; Jiao C; Deng F, 2026, 'Engineering gRNA for CRISPR biosensing: chemical, structural, and programmable designs for ultrasensitive diagnostics', Trac Trends in Analytical Chemistry, 202, http://dx.doi.org/10.1016/j.trac.2026.118960

Hall T; Sang R; Gulati S; Yang M; Zhang C; Goldys EM; Deng F, 2026, 'Circular nucleic acid synthesis: Enzymatic, chemical, and emerging strategies for diagnostic and bioengineering applications', Trac Trends in Analytical Chemistry, 201, pp. 118875, http://dx.doi.org/10.1016/j.trac.2026.118875

Wu Y; Zhou S; Ye X; Zhu T; Deng F; Yang D, 2026, 'Engineering crRNA for CRISPR–Cas12a‐ and Cas13a‐based biosensing: molecular design principles and emerging architectures', Trac Trends in Analytical Chemistry, 201, http://dx.doi.org/10.1016/j.trac.2026.118893

Sang R; Yang B; Zahra K; Deng F; Gu Z; Goldys EM; Deng W, 2026, 'Redox responsive nanosystems for medicine: from reactive species mapping to precision treatment', Advanced Drug Delivery Reviews, 235, http://dx.doi.org/10.1016/j.addr.2026.115892

Li X; Gao X; Gu T; Li Q; Wang L; Deng F; Guo M; Huo D; Hou C, 2026, 'Tribos: A Modular Hairpin-Enhanced CRISPR/Cas12a Biosensor for Ultrasensitive Detection of HER2 Protein', Analytical Chemistry, 98, pp. 21055 - 21063, http://dx.doi.org/10.1021/acs.analchem.6c03581

Long Y; Zhang R; Zhang L; Peng R; Deng F; Hou C; Hou J; Luo X; Huo D, 2026, 'Pollen-stigma biomimetic framework: a CuCo2O4 nanozyme-based electrochemical aptasensor for ultrasensitive aflatoxin B1 detection.', Analyst, http://dx.doi.org/10.1039/d6an00565a

Zhang R; Long Y; Zhang L; Peng R; Ma Y; Deng F; Luo X; Huo D; Hou C, 2026, 'A renewable electrochemical sensor based on highly conductive MOF for simultaneous detection of triple heavy metal ions (Cd2+, Cu2+, and Hg2+) in environmental and food monitoring', Microchemical Journal, 226, http://dx.doi.org/10.1016/j.microc.2026.118295

Liu X; Luo G; Shi F; Wang Q; Deng F; Hou J; Huo D; Hou C, 2026, 'Synergistic signal amplification via DNAzyme-driven DNA walker and MnAu nanozyme for sensitive electrochemical detection of CA15-3', Microchemical Journal, 226, http://dx.doi.org/10.1016/j.microc.2026.118510

Zhai X; Yang B; Deng F; Gulati S; Mckinnirey F; Wu X; Li Y; Goldys EM, 2026, 'CbAgo-enriched Cas12a biosensor for cancer mutations screening', Analytica Chimica Acta, 1403, pp. 345420, http://dx.doi.org/10.1016/j.aca.2026.345420

Zhang Y; Meng J; Jin C; Yang M; Deng F; Luo X; Hou C; Huo D, 2026, 'Engineering asymmetric Fe-N₃-S single-atom nanozymes for multiplexed, on-body sweat analysis and metabolic health monitoring', Chemical Engineering Journal, 538, pp. 176584, http://dx.doi.org/10.1016/j.cej.2026.176584

Zhao R; Bai J; Zhang Q; Wei J; Deng F; Kim M; Li X; Man S; Peng W; Ma L, 2026, 'PfAgo-guided SERS signal conversion for amplification-free and semi-quantitative detection of Salmonella typhimurium in food and physiological samples', Journal of Hazardous Materials, 511, pp. 142193, http://dx.doi.org/10.1016/j.jhazmat.2026.142193

Li X; Gao X; Dong J; Gu T; Li Q; Wang L; Deng F; Hou J; Hou C; Huo D, 2026, 'Aptamer Nanoswitch-Mediated Lock-Expose Mechanism Enables Highly Sensitive In Vitro Detection and Precise In Situ Membrane Imaging of HER2 Protein', ACS Sensors, 11, pp. 4014 - 4023, http://dx.doi.org/10.1021/acssensors.6c00371

Pan L; Sang R; Xue R; Ma Y; Goldys E; Deng F, 2026, 'AlphaFold3-guided tracrRNA redesign yields small monomeric Cas12f RNPs', Nucleic Acids Research, 54, http://dx.doi.org/10.1093/nar/gkag430

Liu X; Shi F; Luo G; Wang Q; Deng F; Luo X; Huo D; Hou C, 2026, 'A Disposable CRISPR-Nanozyme Electrochemical Biosensor for Rapid and Sensitive Detection of Breast Cancer Circulating Tumor DNA', Analytical Chemistry, 98, pp. 12802 - 12810, http://dx.doi.org/10.1021/acs.analchem.6c00173

Peng X; Cao J; Chen C; Zhang K; Yu Y; Deng F; Feng S; Zhao J, 2026, 'Integrated Microfluidic SERS Sensor Featuring Au NPs@Cu MOF/Hydrogel for Label-Free and Specific Creatinine Detection', Analytical Chemistry, 98, pp. 12728 - 12738, http://dx.doi.org/10.1021/acs.analchem.6c00140

Duan Y; Liu M; Men D; Luo Y; Xia X; Wang L; Deng F; Huo D; Hou C, 2026, 'Ultrasensitive detection of tumor marker CA15–3 using a CRISPR/Cas12a-assisted CdTe QDs@ZIF-8 dual-emission fluorescence sensor', Microchemical Journal, 224, pp. 117868, http://dx.doi.org/10.1016/j.microc.2026.117868

Liu H; Jin L; Gao Z; Cui C; Yu Y; Deng F; Gao X; Zhao J; Bian S; Feng S, 2026, 'Droplet-Interlaced Generator with On-Chip Metal–Liquid Micromirrors for Enhanced Microfluidic Absorbance Detection', Biosensors, 16, pp. 202, http://dx.doi.org/10.3390/bios16040202

Mohammadnejad A; Ma L; Goldys E; Deng F, 2026, 'CRISPR-enabled point-of-care diagnostics for SARS-CoV-2 variant surveillance: design principles for adapting molecular detection to viral evolution', Trac Trends in Analytical Chemistry, 199, pp. 118808 - 118808, http://dx.doi.org/10.1016/j.trac.2026.118808

Zhou Y; Xie Y; Qi J; Hu J; Yang Y; Deng F; Zhu Y; Deng W; Mei L; Goldys EM; Zhang J; Xu C; Chen W, 2026, 'A leucine derivate-adjuvanted LNP vaccine enhances antitumor immunity through mTOR activation and metabolic reprograming in dendritic cells', Biomaterials, 325, pp. 123539, http://dx.doi.org/10.1016/j.biomaterials.2025.123539

Deng F; Gulati S; Sang R; Li Y; Goldys EM, 2026, 'Autocatalytic Cas13a biosensor enabled by RNA-nanocircles for ultrasensitive RNA detection', npj Biosensing, 3, pp. 5, http://dx.doi.org/10.1038/s44328-025-00067-6

Long Y; Liu X; Zhang Y; Zhang R; Gu T; Peng R; Deng F; Luo X; Hou C; Huo D, 2026, 'Cascade-activated DNA nano-gating coupled with P-doped Fe single-atom electrocatalyst for ultrasensitive dual-mode detection of circulating tumor DNA', Chemical Engineering Journal, 536, pp. 175784, http://dx.doi.org/10.1016/j.cej.2026.175784

Liu M; Duan Y; Zhao J; Yang S; Wang L; Deng F; Hou J; Huo D; Hou C, 2026, 'Fluorine-free MBene nanosheets as a tunable DNA-binding interface for CRISPR/Cas12a-microfluidic smartphone detection of CA15-3', Chemical Engineering Journal, pp. 180443 - 180443, http://dx.doi.org/10.1016/j.cej.2026.180443

Ma L; Liu Y; Mao Y; Wang J; Chen Y; Deng F; Zhu Z; Ou L; Kim M; Ye S; Peng W; Man S, 2026, 'Multiplexed Thermus thermophilus Argonaute-triggered tri-color fluorescent palette biosensing for rapid detection and genotyping of Helicobacter pylori', Chemical Engineering Journal, 536, pp. 175785, http://dx.doi.org/10.1016/j.cej.2026.175785

Sun R; Liu X; Liu L; Rong H; Gong Y; Le X; Peng W; Peng X; Cheng Z; Tang J; Xiang Q; Nie Y; Yang X; Zhang F; Li R; Wu Y; Zhao Y; Deng F; Zhang M; Xiang T, 2026, 'ZNF334 suppresses colorectal cancer by inducing cell cycle arrest through UCHL1/ZYG11A-mediated perturbation of Cyclin B1–CDK1 complex', Genes & Diseases, pp. 102381 - 102381, http://dx.doi.org/10.1016/j.gendis.2026.102381

Yang F; Xu C; Li C; Xiang X; Zhao Y; Hu C; Rong H; He Y; Li J; Wang Y; Tang C; Liu X; Li R; Deng F; Xiang T, 2025, 'Amplification-free cancer diagnosis based on inhibition of Cas12a activity by site-specific 5mC-modified cfDNA', Nucleic Acids Research, 53, pp. gkaf1383, http://dx.doi.org/10.1093/nar/gkaf1383

Yang Y; Guo J; Qi J; Deng W; Hu J; Hasan MW; Deng F; Zhou Y; Song Z; Deng W; Chen W, 2025, 'A lyophilizable LNP vaccine enables STING-reinforced postoperational adjuvant immunotherapy', Journal of Nanobiotechnology, 23, pp. 379, http://dx.doi.org/10.1186/s12951-025-03445-4

Fu W; Xue R; Shivdasani MN; Wu Y; Chen D; Guo T; Lovell NH; Goldys EM; Xiang T; Huang Y; Deng F, 2025, 'Advances in biosensors for diagnosis and monitoring of inflammatory bowel disease: A review', Bioengineering and Translational Medicine, 10, pp. e70064, http://dx.doi.org/10.1002/btm2.70064

Zhu T; Jiang W; Wu Y; Fang R; Deng F; Yang D, 2025, 'Advances in CRISPR/Cas13a-based biosensors for non-coding RNA detection', Talanta, 294, pp. 128223, http://dx.doi.org/10.1016/j.talanta.2025.128223

Gaba S; Deng F; Jain U, 2025, 'CRISPR-assisted bioanalytical sensing of cytokines', Trac Trends in Analytical Chemistry, 192, pp. 118318, http://dx.doi.org/10.1016/j.trac.2025.118318

Liu X; Luo G; Shi F; Wang Q; Diao Z; Dong L; Deng F; Huo D; Hou C, 2025, 'Dual nanozyme bubble-propelled biosensor for multiple miRNAs detection overcomes spatial hurdles of DNA probes', Biosensors and Bioelectronics, 286, pp. 117624, http://dx.doi.org/10.1016/j.bios.2025.117624

Zahra K; Deng F; Deng W; Sang R, 2025, 'Advances in photodynamic therapy and its combination strategies for breast cancer', Acta Biomaterialia, 205, pp. 125 - 140, http://dx.doi.org/10.1016/j.actbio.2025.08.054

Zou X; Gu T; Li X; Deng L; Zhu S; Dong J; Deng F; Hou C; Huo D, 2025, 'PAM-free activation of CRISPR/Cas12a via semi-nested asymmetric RPA: highly specific detection of HPV16 dsDNA', Analyst, 150, pp. 3891 - 3898, http://dx.doi.org/10.1039/d5an00491h

Hall T; Gulati S; Sang R; Jia Z; Mckinnirey F; Vesey G; Goldys E; Deng F, 2025, 'CRISPR biosensing with lateral flow assays for point of care Diagnostics: Overcoming commercial development challenges', Trac Trends in Analytical Chemistry, 189, pp. 118275, http://dx.doi.org/10.1016/j.trac.2025.118275

Huang Y; Duan W; Deng F; Tang W; Payne SC; Guo T; Goldys EM; Lovell NH; Shivdasani MN, 2025, 'Towards an Implantable Aptamer Biosensor for Monitoring in Inflammatory Bowel Disease', Biosensors, 15, pp. 546, http://dx.doi.org/10.3390/bios15080546

Jin J; Hu J; Yan J; Deng F; Jin S; Yang D, 2025, 'Dual-Mode SERS Lateral Flow Aptamer Assay with Machine Learning-Driven Highly Sensitive Interferon-γ Detection', ACS Synthetic Biology, 14, pp. 2845 - 2853, http://dx.doi.org/10.1021/acssynbio.5c00244

Xie Y; Guo J; Hu J; Li Y; Zhang Z; Zhu Y; Deng F; Qi J; Zhou Y; Chen W, 2025, 'A factorial design-optimized microfluidic LNP vaccine elicits potent magnesium-adjuvating cancer immunotherapy', Materials Today Bio, 32, pp. 101703, http://dx.doi.org/10.1016/j.mtbio.2025.101703

Sang R; Nixdorf S; Hung T; Power C; Deng F; Bui TA; Engel A; Goldys EM; Deng W, 2025, 'Unlocking the in vivo therapeutic potential of radiation-activated photodynamic therapy for locally advanced rectal cancer with lymph node involvement', Ebiomedicine, 116, pp. 105724, http://dx.doi.org/10.1016/j.ebiom.2025.105724

Pan L; Ma Y; Sang R; Lu X; Fan X; Li M; Zuo Q; Wang A; Deng F, 2025, 'Optimization of CRISPR/Cas12f1 guide RNAs using AlphaFold 3 for enhanced nucleic acid detection', Microchemical Journal, 212, pp. 113194, http://dx.doi.org/10.1016/j.microc.2025.113194

Wang Y; Xue Y; Hong X; Wang H; Zhou C; Wang W; Sheng J; Liang P; Li H; Xu Q; Wang Y; Liu K; Shang L; Peng H; Chen F; Zhang K; Yin H; Wang Y; Deng F; Feng S; Huang WE; Li B, 2025, 'Functionalized microwell laser sorting method for single-cell viable microbial detection', Sensors and Actuators B Chemical, 427, pp. 137202, http://dx.doi.org/10.1016/j.snb.2024.137202

Pan L; Jiang W; Deng F; Fang R; Jin S; Yang D, 2025, 'Signal-amplification strategy and advances in electrochemistry-based CRISPR/Cas12 biosensing', Chemical Engineering Journal, 508, pp. 161110, http://dx.doi.org/10.1016/j.cej.2025.161110

Luo X; Hu E; Deng F; Zhang C; Xian Y, 2025, 'A dual-enzyme activated fluorescent probe for precise identification of tumor senescence', Chemical Science, 16, pp. 6507 - 6514, http://dx.doi.org/10.1039/d5sc00103j

Johnston L; Baharfar M; Chi Y; Bardet L; Mousavi M; Deng F; Lin J; Yong J; Liu L; Kalantar-Zadeh K; Tang J, 2025, 'Liquid-Metal-Driven Synthesis of Mesoporous Noble Metal Thin Films and Micropatterns for Biosensing', ACS Nano, 19, pp. 8727 - 8738, http://dx.doi.org/10.1021/acsnano.4c15552

Chia S; Guo T; Goldys EM; Payne SC; Duan W; Lovell NH; Shivdasani MN; Deng F, 2025, 'A CRISPR mediated point-of-care assay for the detection of mucosal calprotectin in an animal model of ulcerative colitis', Bioengineering and Translational Medicine, 10, pp. e10725, http://dx.doi.org/10.1002/btm2.10725

Deng F; Sang R; Li Y; Yang B; Zhai X; Xue R; Zhang C; Deng W; Goldys EM, 2025, 'Hairpin-locker mediated CRISPR/Cas tandem system for ultrasensitive detection of DNA without pre-amplification', Microchemical Journal, 210, pp. 113025, http://dx.doi.org/10.1016/j.microc.2025.113025

Pan L; Wang A; Sang R; Lu X; Chen W; Ma Y; Deng F, 2025, 'AlphaFold 3 sheds insights into chemical enhancer-induced structural changes in Cas12a RNPs', Health Nanotechnology, 1, pp. 1, http://dx.doi.org/10.1186/s44301-024-00003-z

Zheng Y; Liu BX; Zuo QF; Deng F; Lan CH, 2025, 'Detection of Streptococcus anginosus in fecal samples using PCR-CRISPR /Cas12a system', Bioanalysis, 17, pp. 737 - 745, http://dx.doi.org/10.1080/17576180.2025.2518042

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