By Dr Francisco Cruz

Journal articles

Coelho A; Charrua A; Oliveira R; Cavaleiro H; Cruz CD; Cruz F, 2019, 'Underactive bladder in aging rats is associated with a reduced number of serotonin‐expressing cells in the urethra and is improved by serotonin application to the urethra', LUTS Lower Urinary Tract Symptoms, 11, pp. 248 - 254, http://dx.doi.org/10.1111/luts.12273

Antunes-Lopes T; Cruz F, 2019, 'Urinary Biomarkers in Overactive Bladder: Revisiting the Evidence in 2019', European Urology Focus, 5, pp. 329 - 336, http://dx.doi.org/10.1016/j.euf.2019.06.006

Cruz F; Magg S; Nagai Y; Wermter S, 2018, 'Improving interactive reinforcement learning: What makes a good teacher?', Connection Science, 30, pp. 306 - 325, http://dx.doi.org/10.1080/09540091.2018.1443318

Manso M; Alexandre B; Antunes-Lopes T; Martins-da-Silva C; Cruz F, 2018, '¿Es útil el sistema transobturatriz ajustable ATOMS® para el tratamiento de la incontinencia urinaria masculina en centros urológicos de bajo y medio volumen?', Actas Urológicas Españolas (English Edition), 42, pp. 267 - 272, http://dx.doi.org/10.1016/j.acuro.2017.07.011

Angulo JC; Fonseca J; Esquinas C; Ojea A; Rodríguez A; Rabassa M; Teba F; Escribano G; Cruz F, 2018, 'Adjustable transobturator male system (ATOMS®) as treatment of stress urinary incontinence secondary to transurethral resection of the prostate', Actas Urológicas Españolas (English Edition), 42, pp. 567 - 573, http://dx.doi.org/10.1016/j.acuroe.2018.09.002

Angulo JC; Esquinas C; Arance I; Rodríguez A; Pereira J; Rabassa M; Teyrouz A; Teba F; Celada G; Marcelino JP; Martins FE; Manso M; Cruz F, 2018, 'Adjustable Transobturator Male System after Failed Surgical Devices for Male Stress Urinary Incontinence: A Feasibility Study', Urologia Internationalis, 101, pp. 106 - 113, http://dx.doi.org/10.1159/000489316

Roncon-Albuquerque R; Gaião S; Figueiredo P; Príncipe N; Basílio C; Mergulhão P; Silva S; Honrado T; Cruz F; Pestana M; Oliveira G; Meira L; França A; Almeida-Sousa JP; Araújo F; Paiva J-A, 2018, 'An integrated program of extracorporeal membrane oxygenation (ECMO) assisted cardiopulmonary resuscitation and uncontrolled donation after circulatory determination of death in refractory cardiac arrest', Resuscitation, 133, pp. 88 - 94, http://dx.doi.org/10.1016/j.resuscitation.2018.10.016

Nambiar AK; Bosch R; Cruz F; Lemack GE; Thiruchelvam N; Tubaro A; Bedretdinova DA; Ambühl D; Farag F; Lombardo R; Schneider MP; Burkhard FC, 2018, 'EAU Guidelines on Assessment and Nonsurgical Management of Urinary Incontinence', European Urology, 73, pp. 596 - 609, http://dx.doi.org/10.1016/j.eururo.2017.12.031

Coelho A; Oliveira R; Cavaleiro H; Cruz CD; Cruz F, 2018, 'Evidence for an urethro‐vesical crosstalk mediated by serotonin', Neurourology and Urodynamics, 37, pp. 2389 - 2397, http://dx.doi.org/10.1002/nau.23590

Pinto RA; Costa D; Morgado A; Pereira P; Charrua A; Silva J; Cruz F, 2018, 'Intratrigonal OnabotulinumtoxinA Improves Bladder Symptoms and Quality of Life in Patients with Bladder Pain Syndrome/Interstitial Cystitis: A Pilot, Single Center, Randomized, Double-Blind, Placebo Controlled Trial', Journal of Urology, 199, pp. 998 - 1003, http://dx.doi.org/10.1016/j.juro.2017.10.018

Manso M; Pacheco-Figueiredo L; Santos-Silva A; Silva J; Silva C; Cruz F, 2018, 'Renal Cell Carcinoma with Venous Thrombus: Should Surgery Be Offered When Metastasis Is Present at Diagnosis?', Urologia Internationalis, 101, pp. 387 - 390, http://dx.doi.org/10.1159/000493510

Kreydin E; Welk B; Chung D; Clemens Q; Yang C; Danforth T; Gousse A; Kielb S; Kraus S; Mangera A; Reid S; Szell N; Cruz F; Chartier-Kastler E; Ginsberg DA, 2018, 'Surveillance and management of urologic complications after spinal cord injury', World Journal of Urology, 36, pp. 1545 - 1553, http://dx.doi.org/10.1007/s00345-018-2345-0

Angulo JC; Cruz F; Esquinas C; Arance I; Manso M; Rodríguez A; Pereira J; Ojea A; Carballo M; Rabassa M; Teyrouz A; Escribano G; Rodríguez E; Teba F; Celada G; Madurga B; Álvarez‐Ossorio JL; Marcelino JP; Martins FE, 2018, 'Treatment of male stress urinary incontinence with the adjustable transobturator male system: Outcomes of a multi‐center Iberian study', Neurourology and Urodynamics, 37, pp. 1458 - 1466, http://dx.doi.org/10.1002/nau.23474

Antunes-Lopes T; Coelho A; Pinto R; Barros SC; Cruz CD; Cruz F; Silva CM, 2017, 'Author Reply', Urology, 99, pp. 55 - 56, http://dx.doi.org/10.1016/j.urology.2016.08.050

Coelho A; Antunes‐Lopes T; Gillespie J; Cruz F, 2017, 'Beta‐3 adrenergic receptor is expressed in acetylcholine‐containing nerve fibers of the human urinary bladder: An immunohistochemical study', Neurourology and Urodynamics, 36, pp. 1972 - 1980, http://dx.doi.org/10.1002/nau.23224

Chapple CR; Cruz F; Deffieux X; Milani AL; Arlandis S; Artibani W; Bauer RM; Burkhard F; Cardozo L; Castro-Diaz D; Cornu JN; Deprest J; Gunnemann A; Gyhagen M; Heesakkers J; Koelbl H; MacNeil S; Naumann G; Roovers J-PWR; Salvatore S; Sievert K-D; Tarcan T; Van der Aa F; Montorsi F; Wirth M; Abdel-Fattah M, 2017, 'Consensus Statement of the European Urology Association and the European Urogynaecological Association on the Use of Implanted Materials for Treating Pelvic Organ Prolapse and Stress Urinary Incontinence', European Urology, 72, pp. 424 - 431, http://dx.doi.org/10.1016/j.eururo.2017.03.048

Oliveira R; Coelho A; Charrua A; Avelino A; Cruz F, 2017, 'Expression of cleaved SNAP‐25 after bladder wall injection of onabotulinumtoxina or abobotulinumtoxina: A comparative study in the mice', Neurourology and Urodynamics, 36, pp. 86 - 90, http://dx.doi.org/10.1002/nau.22900

Matos R; Serrão P; Rodriguez L; Birder LA; Cruz F; Charrua A, 2017, 'The water avoidance stress induces bladder pain due to a prolonged alpha1A adrenoceptor stimulation', Naunyn-Schmiedeberg's Archives of Pharmacology, 390, pp. 839 - 844, http://dx.doi.org/10.1007/s00210-017-1384-1

Antunes-Lopes T; Coelho A; Pinto R; Barros SC; Cruz CD; Cruz F; Silva CM, 2017, 'Urinary Neurotrophin Levels Increase in Women With Stress Urinary Incontinence After a Midurethral Sling Procedure', Urology, 99, pp. 49 - 56, http://dx.doi.org/10.1016/j.urology.2016.08.048

Cruz F; Magg S; Weber C; Wermter S, 2016, 'Training Agents With Interactive Reinforcement Learning and Contextual Affordances', IEEE Transactions on Cognitive and Developmental Systems, 8, pp. 271 - 284, http://dx.doi.org/10.1109/TCDS.2016.2543839

Cruz F; Baraglia J; Nagai Y; Wermter S, 2016, 'Special issue on bio-inspired social robot learning in home scenarios', IEEE Transactions on Cognitive and Developmental Systems, 8, pp. 1 - 2, http://dx.doi.org/10.1109/TCDS.2016.2603000

Matos R; Cordeiro JM; Coelho A; Ferreira S; Silva C; Igawa Y; Cruz F; Charrua A, 2016, 'Bladder pain induced by prolonged peripheral alpha 1A adrenoceptor stimulation involves the enhancement of transient receptor potential vanilloid 1 activity and an increase of urothelial adenosine triphosphate release', Acta Physiologica, 218, pp. 265 - 275, http://dx.doi.org/10.1111/apha.12744

Rodrigues de Carvalho TG; Pinto R; Cruz F; Silva J, 2016, 'EFFECT OF ONABOTULINUM TOXIN TYPE A INTRAPROSTATIC INJECTION ON THE OUTCOME OF BENIGN PROSTATIC HYPERPLASIA PATIENTS REFRACTORY TO MEDICAL THERAPY: A 2-YEAR FOLLOW-UP STUDY', ARCHIVOS ESPANOLES DE UROLOGIA, 69, pp. 719 - 726

Montorsi F; Gandaglia G; Chapple C; Cruz F; Desgrandchamps F; Llorente C, 2016, 'Effectiveness and safety of silodosin in the treatment of lower urinary tract symptoms in patients with benign prostatic hyperplasia: A European phase IV clinical study (SiRE study)', International Journal of Urology, 23, pp. 572 - 579, http://dx.doi.org/10.1111/iju.13088

Martins-Silva C; Cruz F, 2016, 'Efficacy and Safety of OnabotulinumtoxinA in Patients with Urinary Incontinence Due to Neurogenic Detrusor Overactivity: Update of the Pivotal Randomised, Double-blind, Placebo-controlled Trials', European Urology Focus, 2, pp. 329 - 331, http://dx.doi.org/10.1016/j.euf.2016.04.003

Antunes-Lopes T; da Silva CM; Cruz F, 2016, 'Evaluation of the Donor After Brain Death and Technique for Organ Procurement', European Urology Open Science, 15, pp. 390 - 396, http://dx.doi.org/10.1016/j.eursup.2016.08.004

Coelho A; Oliveira R; Cruz F; Cruz CD, 2016, 'Impairment of sensory afferents by intrathecal administration of botulinum toxin A improves neurogenic detrusor overactivity in chronic spinal cord injured rats', Experimental Neurology, 285, pp. 159 - 166, http://dx.doi.org/10.1016/j.expneurol.2016.05.029

Cruz F, 2016, 'Re: Efficacy and Safety of Mirabegron Add-on Therapy to Solifenacin in Incontinent Overactive Bladder Patients with an Inadequate Response to Initial 4-week Solifenacin Monotherapy: A Randomised Double-blind Multicentre Phase 3B Study (BESIDE)', European Urology, 70, pp. 892, http://dx.doi.org/10.1016/j.eururo.2016.08.027

Roehrborn CG; Cruz F; Fusco F, 2016, 'α1-Blockers in Men with Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Obstruction: Is Silodosin Different?', Advances in Therapy, 33, pp. 2110 - 2121, http://dx.doi.org/10.1007/s12325-016-0423-5

Dinis S; de Oliveira JT; Pinto R; Cruz F; Buffington CT; Dinis P, 2015, 'From bladder to systemic syndrome: concept and treatment evolution of interstitial cystitis', International Journal of Women's Health, 7, pp. 735 - 744, http://dx.doi.org/10.2147/ijwh.s60798

Frias B; Santos J; Morgado M; Sousa MM; Gray SMY; McCloskey KD; Allen S; Cruz F; Cruz CD, 2015, 'The Role of Brain-Derived Neurotrophic Factor (BDNF) in the Development of Neurogenic Detrusor Overactivity (NDO)', Journal of Neuroscience, 35, pp. 2146 - 2160, http://dx.doi.org/10.1523/jneurosci.0373-14.2015

Cruz CD; Coelho A; Antunes-Lopes T; Cruz F, 2015, 'Biomarkers of spinal cord injury and ensuing bladder dysfunction', Advanced Drug Delivery Reviews, 82, pp. 153 - 159, http://dx.doi.org/10.1016/j.addr.2014.11.007

Laterza RM; Sievert K; de Ridder D; Vierhout ME; Haab F; Cardozo L; van Kerrebroeck P; Cruz F; Kelleher C; Chapple C; Espuña‐Pons M; Koelbl H, 2015, 'Bladder function after radical hysterectomy for cervical cancer', Neurourology and Urodynamics, 34, pp. 309 - 315, http://dx.doi.org/10.1002/nau.22570

Charrua A; Pinto R; Taylor A; Canelas A; Ribeiro-da-Silva A; Cruz CD; Birder LA; Cruz F, 2015, 'Can the adrenergic system be implicated in the pathophysiology of bladder pain syndrome/interstitial cystitis? A clinical and experimental study', Neurourology and Urodynamics, 34, pp. 489 - 496, http://dx.doi.org/10.1002/nau.22542

Charrua A; Cruz CD; Jansen D; Rozenberg B; Heesakkers J; Cruz F, 2015, 'Co‐administration of transient receptor potential vanilloid 4 (TRPV4) and TRPV1 antagonists potentiate the effect of each drug in a rat model of cystitis', BJU International, 115, pp. 452 - 460, http://dx.doi.org/10.1111/bju.12861

Bunn F; Kirby M; Pinkney E; Cardozo L; Chapple C; Chester K; Cruz F; Haab F; Kelleher C; Milsom I; Sievart KD; Tubaro A; Wagg A, 2015, 'Is there a link between overactive bladder and the metabolic syndrome in women? A systematic review of observational studies', International Journal of Clinical Practice, 69, pp. 199 - 217, http://dx.doi.org/10.1111/ijcp.12518

Camões J; Coelho A; Castro-Diaz D; Cruz F, 2015, 'Lower Urinary Tract Symptoms and Aging: The Impact of Chronic Bladder Ischemia on Overactive Bladder Syndrome', Urologia Internationalis, 95, pp. 373 - 379, http://dx.doi.org/10.1159/000437336

Cruz F, 2015, 'Re: Combination Treatment with Mirabegron and Solifenacin in Patients with Overactive Bladder: Efficacy and Safety Results from a Randomised, Double-blind, Dose-ranging, Phase 2 Study (Symphony)', European Urology, 67, pp. 1189 - 1190, http://dx.doi.org/10.1016/j.eururo.2015.02.017

Charrua A; Pinto R; Birder LA; Cruz F, 2015, 'Sympathetic nervous system and chronic bladder pain: a new tune for an old song', Translational Andrology and Urology, 4, pp. 534 - 542, http://dx.doi.org/10.3978/j.issn.2223-4683.2015.09.06

Cruz F, 2015, 'Transient receptor potential channel: a reality that still requires many years of scientific efforts', BJU International, 115, pp. 676 - 677, http://dx.doi.org/10.1111/bju.12944

Coelho A; Wolf‐Johnston AS; Shinde S; Cruz CD; Cruz F; Avelino A; Birder LA, 2015, 'Urinary bladder inflammation induces changes in urothelial nerve growth factor and TRPV1 channels', British Journal of Pharmacology, 172, pp. 1691 - 1699, http://dx.doi.org/10.1111/bph.12958

Antunes-Lopes T; Pinto R; Morgado P; Madaleno P; Silva J; Silva C; Cruz F, 2014, 'Intrarenal artery pseudoaneurysm after blunt abdominal trauma: a case report of successful superselective angioembolization', Research and Reports in Urology, 6, pp. 17 - 20, http://dx.doi.org/10.2147/rru.s58291

Araújo JR; Silva SE; Cruz F; Falcão-Reis F, 2014, 'Acute Transient Myopia With Shallowing of the Anterior Chamber Induced by Sulfamethoxazole in a Patient With Pseudoxanthoma Elasticum', Journal of Glaucoma, 23, pp. 415 - 417, http://dx.doi.org/10.1097/ijg.0000000000000074

Antunes-Lopes T; Cruz CD; Cruz F; Sievert KD, 2014, 'Biomarkers in lower urinary tract symptoms/overactive bladder', Current Opinion in Urology, 24, pp. 352 - 357, http://dx.doi.org/10.1097/mou.0000000000000064

Pina F; Botelho F; Lopes T; Lopes I; Figueiredo G; Portugal R; Ferro A; Cruz F; Barros H; Lunet N, 2014, 'Can serum angiogenin be used to improve the diagnostic performance in prostate cancer screening?', European Journal of Cancer Prevention, 23, pp. 166 - 172, http://dx.doi.org/10.1097/cej.0b013e3283647453

Cruz F; Nitti V, 2014, 'Chapter 5: Clinical data in neurogenic detrusor overactivity (NDO) and overactive bladder (OAB)', Neurourology and Urodynamics, 33, pp. s26 - s31, http://dx.doi.org/10.1002/nau.22630

Eisenhardt A; Schneider T; Cruz F; Oelke M, 2014, 'Consistent and significant improvement of nighttime voiding frequency (nocturia) with silodosin in men with LUTS suggestive of BPH: pooled analysis of three randomized, placebo-controlled, double-blind phase III studies', World Journal of Urology, 32, pp. 1119 - 1125, http://dx.doi.org/10.1007/s00345-013-1228-7

Silva J; Silva CM; Cruz F, 2014, 'Current medical treatment of lower urinary tract symptoms/BPH', Current Opinion in Urology, 24, pp. 21 - 28, http://dx.doi.org/10.1097/mou.0000000000000007

Ginsberg D; Cruz F; Herschorn S; Gousse A; Keppenne V; Aliotta P; Sievert K-D; Brin MF; Jenkins B; Thompson C; Lam W; Heesakkers J; Haag-Molkenteller C, 2014, 'Erratum to: OnabotulinumtoxinA is Effective in Patients with Urinary Incontinence due to Neurogenic Detrusor Overactivity Regardless of Concomitant Anticholinergic Use or Neurologic Etiology', Advances in Therapy, 31, pp. 242 - 242, http://dx.doi.org/10.1007/s12325-014-0103-2

Coelho A; Oliveira R; Rossetto O; Cruz CD; Cruz F; Avelino A, 2014, 'Intrathecal administration of botulinum toxin type A improves urinary bladder function and reduces pain in rats with cystitis', European Journal of Pain, 18, pp. 1480 - 1489, http://dx.doi.org/10.1002/ejp.513

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