By Dr Janet Newman

Books

, 2019, Supercomputing Frontiers, Abramson D; de Supinski BR, (ed.), Springer International Publishing, http://dx.doi.org/10.1007/978-3-030-18645-6

Book Chapters

Watkins CJ; Rosa N; Carroll T; Ratcliffe D; Ristic M; Russell C; Li R; Fazio V; Newman J, 2019, 'A Crystal/Clear Pipeline for Applied Image Processing', in Abramson D; DeSupinski BR (ed.), , SPRINGER INTERNATIONAL PUBLISHING AG, pp. 19 - 37, http://dx.doi.org/10.1007/978-3-030-18645-6_2

Fazio VJ; Peat TS; Newman J, 2015, 'Crystallization: Digging into the past to learn lessons for the future', in , pp. 141 - 159, http://dx.doi.org/10.1007/978-1-4939-2230-7_8

Journal articles

Joho Y; Royan S; Caputo AT; Newton S; Peat TS; Newman J; Jackson C; Ardevol A, 2024, 'Enhancing PET Degrading Enzymes: A Combinatory Approach', ChemBioChem, 25, http://dx.doi.org/10.1002/cbic.202400084

Sharma S; Chung CY; Uryu S; Petrovic J; Cao J; Rickard A; Nady N; Greasley S; Johnson E; Brodsky O; Khan S; Wang H; Wang Z; Zhang Y; Tsaparikos K; Chen L; Mazurek A; Lapek J; Kung PP; Sutton S; Richardson PF; Greenwald EC; Yamazaki S; Jones R; Maegley KA; Bingham P; Lam H; Stupple AE; Kamal A; Chueh A; Cuzzupe A; Morrow BJ; Ren B; Carrasco-Pozo C; Tan CW; Bhuva DD; Allan E; Surgenor E; Vaillant F; Pehlivanoglu H; Falk H; Whittle JR; Newman J; Cursons J; Doherty JP; White KL; MacPherson L; Devlin M; Dennis ML; Hattarki MK; De Silva M; Camerino MA; Butler MS; Dolezal O; Pilling P; Foitzik R; Stupple PA; Lagiakos HR; Walker SR; Hediyeh-Zadeh S; Nuttall S; Spall SK; Charman SA; Connor T; Peat TS; Avery VM; Bozikis YE; Yang Y; Zhang M; Monahan BJ; Voss AK; Thomas T; Street IP; Dawson SJ; Dawson MA; Lindeman GJ; Davis MJ; Visvader JE; Paul TA, 2023, 'Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer', Cell Chemical Biology, 30, pp. 1191 - 1210.e20, http://dx.doi.org/10.1016/j.chembiol.2023.07.005

Rosa N; Watkins CJ; Newman J, 2023, 'Moving beyond MARCO', PLOS ONE, 18, http://dx.doi.org/10.1371/journal.pone.0283124

Baker EN; Bond CS; Garman EF; Newman J; Read RJ; Van Raaij MJ, 2022, 'Submission of structural biology data for review purposes', IUCrJ, 9, pp. 1 - 2, http://dx.doi.org/10.1107/S2052252521012999

Guo Z; Smutok O; Johnston WA; Walden P; Ungerer JPJ; Peat TS; Newman J; Parker J; Nebl T; Hepburn C; Melman A; Suderman RJ; Katz E; Alexandrov K, 2021, 'Design of a methotrexate-controlled chemical dimerization system and its use in bio-electronic devices', Nature Communications, 12, http://dx.doi.org/10.1038/s41467-021-27184-w

Caputo AT; Eder OM; Bereznakova H; Pothuis H; Ardevol A; Newman J; Nuttall S; Peat TS; Adams TE, 2021, 'Structure-guided selection of puromycin N-acetyltransferase mutants with enhanced selection stringency for deriving mammalian cell lines expressing recombinant proteins', Scientific Reports, 11, http://dx.doi.org/10.1038/s41598-021-84551-9

Baker EN; Bond CS; Garman EF; Newman J; Read RJ; Van Raaij MJ, 2021, 'Submission of structural biology data for review purposes', Acta Crystallographica Section F: Structural Biology Communications, 77, pp. 435 - 436, http://dx.doi.org/10.1107/S2053230X21012681

Baker EN; Bond CS; Garman EF; Newman J; Read RJ; van Raaij MJ, 2021, 'Submission of structural biology data for review purposes.', Acta Crystallogr F Struct Biol Commun, 77, pp. 435 - 436, http://dx.doi.org/10.1107/S2053230X21012681

Abrahams G; Newman J, 2021, 'Data- and diversity-driven development of a Shotgun crystallization screen using the Protein Data Bank', ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 77, pp. 1437 - 1450, http://dx.doi.org/10.1107/S2059798321009724

Helliwell JR; Newman J; van Raaij MJ, 2021, 'Topical Reviews in Acta Crystallographica F Structural Biology Communications', ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 77, pp. 385 - 385, http://dx.doi.org/10.1107/S2053230X21011195

Dong L; McKinstry WJ; Pan L; Newman J; Ren B, 2021, 'Crystal structure of fungal tannase from Aspergillus niger', ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 77, pp. 267 - 277, http://dx.doi.org/10.1107/S2059798320016484

Abrahams G; Newman J, 2021, 'Data and Diversity Driven Development of a Shotgun Crystallisation Screen using the Protein Data Bank', , http://dx.doi.org/10.1101/2021.08.11.456002

Newman J; Nebl T; Van H; Peat TS, 2020, 'The X-ray crystal structure of the N-terminal domain of Ssr4, a Schizosaccharomyces pombe chromatin-remodelling protein', Acta Crystallographica Section F: Structural Biology Communications, 76, pp. 583 - 589, http://dx.doi.org/10.1107/S2053230X20015216

Klemm T; Ebert G; Calleja DJ; Allison CC; Richardson LW; Bernardini JP; Lu BGC; Kuchel NW; Grohmann C; Shibata Y; Gan ZY; Cooney JP; Doerflinger M; Au AE; Blackmore TR; van der Heden van Noort GJ; Geurink PP; Ovaa H; Newman J; Riboldi-Tunnicliffe A; Czabotar PE; Mitchell JP; Feltham R; Lechtenberg BC; Lowes KN; Dewson G; Pellegrini M; Lessene G; Komander D, 2020, 'Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2', EMBO Journal, 39, http://dx.doi.org/10.15252/embj.2020106275

Newman J; van Raaij MJ, 2020, 'Contamination or serendipity - doing the wrong thing by chance', ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 76, pp. 391 - 391, http://dx.doi.org/10.1107/S2053230X20012029

Dennis ML; Newman J; Dolezal O; Hattarki M; Surjadi RN; Nuttall SD; Pham T; Nebl T; Camerino M; Khoo PS; Monahan BJ; Peat TS, 2020, 'Crystal structures of human ENPP1 in apo and bound forms', Acta Crystallographica Section D: Structural Biology, 76, pp. 889 - 898, http://dx.doi.org/10.1107/S2059798320010505

Newman J; van Raaij MJ, 2020, 'Innovation versus practice in biological crystallization', ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 76, pp. 290 - 291, http://dx.doi.org/10.1107/S2053230X20008869

Wilson J; Ristic M; Kirkwood J; Hargreaves D; Newman J, 2020, 'Predicting the Effect of Chemical Factors on the pH of Crystallization Trials', iScience, 23, http://dx.doi.org/10.1016/j.isci.2020.101219

Rosa N; Ristic M; Thorburn L; Abrahams GJ; Marshall B; Watkins CJ; Kruger A; Khassapov A; Newman J, 2020, 'Tools to Ease the Choice and Design of Protein Crystallisation Experiments', CRYSTALS, 10, http://dx.doi.org/10.3390/cryst10020095

Esquirol L; Peat TS; Sugrue E; Balotra S; Rottet S; Warden AC; Wilding M; Hartley CJ; Jackson CJ; Newman J; Scott C, 2020, 'Bacterial catabolism of s-triazine herbicides: biochemistry, evolution and application', Advances in Microbial Physiology, 76, pp. 129 - 186, http://dx.doi.org/10.1016/bs.ampbs.2020.01.004

Dennis ML; Morrow BJ; Dolezal O; Cuzzupe AN; Stupple AE; Newman J; Bentley J; Hattarki M; Nuttall SD; Foitzik RC; Street IP; Stupple PA; Monahan BJ; Peat TS, 2019, 'Fragment screening for a protein-protein interaction inhibitor to WDR5', Structural Dynamics, 6, http://dx.doi.org/10.1063/1.5122849

van Raaij MJ; Newman J, 2019, 'Taking biological structure communications into the third dimension', ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 75, pp. 663 - 664, http://dx.doi.org/10.1107/S2053230X19014754

Dennis ML; Esquirol L; Nebl T; Newman J; Scott C; Peat TS, 2019, 'The evolving story of AtzT, a periplasmic binding protein', Acta Crystallographica Section D: Structural Biology, 75, pp. 995 - 1002, http://dx.doi.org/10.1107/S2059798319013883

Newman J; van Raaij MJ, 2019, 'Introducing Methods Communications, a new category of contributions to Acta Crystallographica F', ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 75, pp. 529 - 530, http://dx.doi.org/10.1107/S2053230X19010306

Helliwell JR; Minor W; Weiss MS; Garman EF; Read RJ; Newman J; van Raaij MJ; Hajdu J; Baker EN, 2019, 'Findable Accessible Interoperable Re-usable (FAIR) diffraction data are coming to protein crystallography', JOURNAL OF APPLIED CRYSTALLOGRAPHY, 52, pp. 495 - 497, http://dx.doi.org/10.1107/S1600576719005922

Helliwell JR; Minor W; Weiss MS; Garman EF; Read RJ; Newman J; van Raaij MJ; Hajdu J; Baker EN, 2019, 'Findable Accessible Interoperable Re-usable (FAIR) diffraction data are coming to protein crystallography', ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 75, pp. 321 - 323, http://dx.doi.org/10.1107/S2053230X19005909

Helliwell JR; Minor W; Weiss MS; Garman EF; Read RJ; Newman J; van Raaij MJ; Hajdu J; Baker EN, 2019, 'Findable Accessible Interoperable Re-usable (FAIR) diffraction data are coming to protein crystallography', IUCRJ, 6, pp. 341 - 343, http://dx.doi.org/10.1107/S2052252519005918

Helliwell JR; Minor W; Weiss MS; Garman EF; Read RJ; Newman J; van Raaij MJ; Hajdu J; Baker EN, 2019, 'Findable Accessible Interoperable Re-usable (FAIR) diffraction data are coming to protein crystallography', ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 75, pp. 455 - 457, http://dx.doi.org/10.1107/S2059798319004844

Abrahams GJ; Newman J, 2019, 'BLASTing away preconceptions in crystallization trials', ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 75, pp. 184 - 192, http://dx.doi.org/10.1107/S2053230X19000141

Newman J; Caron K; Nebl T; Peat TS, 2019, 'Structures of the transcriptional regulator BgaR, a lactose sensor', Acta Crystallographica Section D: Structural Biology, 75, pp. 639 - 646, http://dx.doi.org/10.1107/S2059798319008131

Esquirol L; Peat TS; Wilding M; Hartley CJ; Newman J; Scott C, 2018, 'A novel decarboxylating amidohydrolase involved in avoiding metabolic dead ends during cyanuric acid catabolism in Pseudomonas sp. Strain ADP', PLoS ONE, 13, http://dx.doi.org/10.1371/journal.pone.0206949

Rosa N; Ristic M; Marshall B; Newman J, 2018, 'Cinder: keeping crystallographers app-y', ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 74, pp. 410 - 418, http://dx.doi.org/10.1107/S2053230X18008038

Bruno AE; Charbonneau P; Newman J; Snell EH; So DR; Vanhoucke V; Watkins CJ; Williams S; Wilson J, 2018, 'Classification of crystallization outcomes using deep convolutional neural networks', PLOS ONE, 13, http://dx.doi.org/10.1371/journal.pone.0198883

Esquirol L; Peat TS; Wilding M; Liu JW; French NG; Hartley CJ; Onagi H; Nebl T; Easton CJ; Newman J; Scott C, 2018, 'An unexpected vestigial protein complex reveals the evolutionary origins of an s-triazine catabolic enzyme', Journal of Biological Chemistry, 293, pp. 7880 - 7891, http://dx.doi.org/10.1074/jbc.RA118.001996

Gu A; Marshall B; Rosa N; Ristic M; Newman J, 2018, 'Organizing a crystallization laboratory', JOURNAL OF APPLIED CRYSTALLOGRAPHY, 51, pp. 47 - 54, http://dx.doi.org/10.1107/S1600576717016727

Esquirol L; Peat TS; Wilding M; Lucent D; French NG; Hartley CJ; Newman J; Scott C, 2018, 'Structural and biochemical characterization of the biuret hydrolase (BiuH) from the cyanuric acid catabolism pathway of Rhizobium leguminasorum bv. viciae 3841', PLoS ONE, 13, http://dx.doi.org/10.1371/journal.pone.0192736

Newman J; Sharp JA; Enjapoori AK; Bentley J; Nicholas KR; Adams TE; Peat TS, 2018, 'Structural characterization of a novel monotreme-specific protein with antimicrobial activity from the milk of the platypus', Acta Crystallographica Section F: Structural Biology Communications, 74, pp. 39 - 45, http://dx.doi.org/10.1107/S2053230X17017708

Zabara A; Meikle TG; Trenker R; Yao S; Newman J; Peat TS; Separovic F; Conn CE; Call MJ; Call ME; Landau EM; Drummond CJ, 2017, 'Lipidic Cubic Phase-Induced Membrane Protein Crystallization: Interplay between Lipid Molecular Structure, Mesophase Structure and Properties, and Crystallogenesis', Crystal Growth and Design, 17, pp. 5667 - 5674, http://dx.doi.org/10.1021/acs.cgd.7b00519

Peat TS; Balotra S; Wilding M; Hartley CJ; Newman J; Scott C, 2017, 'High-resolution X-ray structures of two functionally distinct members of the cyclic amide hydrolase family of Toblerone fold enzymes', Applied and Environmental Microbiology, 83, http://dx.doi.org/10.1128/AEM.03365-16

Davies C; Böttcher C; Boss PK; Peat T; Newman J, 2017, 'Understanding the control of grape berry ripening and developing opportunities for its manipulation', Acta Horticulturae, 1157, pp. 1 - 10, http://dx.doi.org/10.17660/ActaHortic.2017.1157.1

Zabara A; Meikle TG; Newman J; Peat TS; Conn CE; Drummond CJ, 2017, 'The nanoscience behind the art of: In-meso crystallization of membrane proteins', Nanoscale, 9, pp. 754 - 763, http://dx.doi.org/10.1039/c6nr07634c

Wilding M; Scott C; Newman J; Peat TS, 2017, 'Crystal structure of a putrescine aminotransferase from Pseudomonas sp. strain AAC', Acta Crystallographica Section:F Structural Biology Communications, 73, pp. 29 - 35, http://dx.doi.org/10.1107/S2053230X16019658

Land N; De Seta G; Berti P, 2017, 'Meltdown', SGUARDO-RIVISTA DI FILOSOFIA, pp. 269 - 279, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000422630200018&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Silk MR; Newman J; Ratcliffe JC; White JF; Caradoc-Davies T; Price JR; Perrier S; Thompson PE; Chalmers DK, 2017, 'Parallel and antiparallel cyclic d/l peptide nanotubes', Chemical Communications, 53, pp. 6613 - 6616, http://dx.doi.org/10.1039/c7cc00846e

Wilding M; Peat TS; Kalyaanamoorthy S; Newman J; Scott C; Jermiin LS, 2017, 'Reverse engineering: Transaminase biocatalyst development using ancestral sequence reconstruction', Green Chemistry, 19, pp. 5375 - 5380, http://dx.doi.org/10.1039/c7gc02343j

Wilding M; Scott C; Peat TS; Newman J, 2017, 'X-ray crystal structure of a malonate-semialdehyde dehydrogenase from Pseudomonas sp. strain AAC', Acta Crystallographica Section:F Structural Biology Communications, 73, pp. 24 - 28, http://dx.doi.org/10.1107/S2053230X16020008

Brewster JL; McKellar JLO; Finn TJ; Newman J; Peat TS; Gerth ML, 2016, 'Structural basis for ligand recognition by a Cache chemosensory domain that mediates carboxylate sensing in Pseudomonas syringae', Scientific Reports, 6, http://dx.doi.org/10.1038/srep35198

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