By Dr Longting Lin

Journal articles

Liu F; Chen C; Chen C; Parsons MW; Li G; Lin L, 2025, 'Salvageable Time Window: Tissue Clock After Acute Ischemic Stroke Onset', Stroke, 56, pp. 3165 - 3174, http://dx.doi.org/10.1161/STROKEAHA.125.051780

Lee P; Wu T; Chen C; Lin L; Garcia-Esperon C; Cordato DJ; Miteff F; Kleinig TJ; Choi PMC; Xin C; Barber PA; Ranta A; Fink JN; Parsons MW; Gao L, 2025, 'Cost-Effectiveness of Endovascular Thrombectomy in Large Vessel Occlusion Stroke for the Very Elderly', Neurology, 105, pp. e214079, http://dx.doi.org/10.1212/WNL.0000000000214079

Thomas JO; Visser M; Garcia-Esperon C; Spratt NJ; Cordato D; Cappelen-Smith C; Lin L; Parsons MW, 2025, 'CT perfusion lesions are present in most MRI confirmed lacunar strokes.', Neuroimage Clin, 48, pp. 103903, http://dx.doi.org/10.1016/j.nicl.2025.103903

Edwards LS; Cappelen-Smith C; Cordato D; Bivard A; Churilov L; Lin L; Chen C; Garcia-Esperon C; Parsons MW, 2025, 'Optimizing CTP in Posterior Circulation Infarction (POCI): A Comprehensive Analysis of CTP Postprocessing Algorithms for POCI', American Journal of Neuroradiology, 46, pp. 2243 - 2252, http://dx.doi.org/10.3174/ajnr.A8833

Yang H; George Y; Mehta D; Lin L; Chen C; Yang D; Sun J; Lau KF; Bain C; Yang Q; Parsons MW; Ge Z, 2025, 'Multi-modal CT Perfusion-based Deep Learning for Predicting Stroke Lesion Outcomes in Complete and No Recanalization Scenarios.', AJNR Am J Neuroradiol, http://dx.doi.org/10.3174/ajnr.A9016

He Z; Hong L; Ling Y; Li S; Liu X; Wang X; Dong Q; Cheng X, 2025, 'Baseline Blood Pressure Was Associated with Hemispheric Cerebral Blood Flow in Acute Small Subcortical Infarcts', Cerebrovascular Diseases, 54, pp. 467 - 475, http://dx.doi.org/10.1159/000541700

Gao L; Tan E; Chen C; Kleinig T; Yan B; Cheung A; Levi C; Garcia-Esperon C; Cordato D; Blair C; Lin L; Parsons M; Bivard A, 2025, 'Cost-Effectiveness of Endovascular Thrombectomy in M2 Occlusion Stroke: Real-World Experience Versus Clinical Trials', Journal of Endovascular Therapy, 32, pp. 1047 - 1055, http://dx.doi.org/10.1177/15266028231201098

Liu Y; Lu G; Li D; Wu G; Zhou X; Qu R; Fang Y; He Z; Zhang A; Hong L; Fang K; Cheng X; Dong Q, 2025, 'Tenecteplase thrombolytic therapy for acute ischaemic stroke in China: A real-world, multicentre, retrospective, controlled study', Stroke and Vascular Neurology, 10, pp. 452 - 461, http://dx.doi.org/10.1136/svn-2024-003381

Hong L; Lin L; Chen C; Bivard A; Levi CR; Su Y; Ling Y; Parsons MW; Cheng X; Dong Q, 2025, 'Persistent penumbral profiles indicate a potentially good outcome in acute stroke patients without major reperfusion', International Journal of Stroke, 20, pp. 687 - 695, http://dx.doi.org/10.1177/17474930251318921

Pidugun V; Wardman D; Thomas P; Badge H; Ji J; Chen C; Pham T; Cheung AK; Manning N; Blair C; Cappelen-Smith C; Lin L; Hodgkinson SJ; McDougall A; Parsons M; Cordato D, 2025, 'Time to endovascular thrombectomy for acute ischaemic stroke in language other than English (LOTE) communities in South-Western Sydney', BMJ Neurology Open, 7, http://dx.doi.org/10.1136/bmjno-2025-001114

Kim N; Ryu WS; Ha SY; Kim JY; Kang J; Baik SH; Jung C; Han MK; Bae HJ; Lin L; Parsons M; Kim BJ, 2025, 'Optimal Cerebral Blood Flow Thresholds for Ischemic Core Estimation Using Computed Tomography Perfusion and Diffusion-Weighted Imaging', Annals of Neurology, 97, pp. 919 - 929, http://dx.doi.org/10.1002/ana.27169

Lin L; Liu F; Yi T; Zhu Y; Yang J; Zhao Y; Wang F; Xiang G; Chen C; Xiao Y; Shen H; Xu L; Long Y; Zhang Y; Huang Z; Chen C; Churilov L; Parsons MW; Chen W; Li G; Zhang H; Jiang C; Xu Z; Wang Q; Wang Y; Yu M; Yang W; Wang X; Fu W; Wu Y; Lin D; Lin X; Pan Z; Zeng L; He Y; Chen X; Zhou J; Zhao F; Zhu T; Wang D; Gao M; Shi W; Deng J; Lu H; Wei L; Gu Y; Zhang Y; He Z; Liang Y; Qian Z; Guo P; Pan Z; Wu Y; Huang Y; Liu R; Wei C; Han D, 2025, 'Tirofiban on First-Pass Recanalization in Acute Stroke Endovascular Thrombectomy: The OPTIMISTIC Randomized Clinical Trial', JAMA Network Open, 8, pp. e255308, http://dx.doi.org/10.1001/jamanetworkopen.2025.5308

Jiang P; Yu W; Wang X; Gao S; Geng Y; Guo S; shen Q; Lin L; Parsons M; Zhang S, 2025, 'Post-Thrombectomy Mild Hypercapnia State Prevents Poor Outcome by Reducing Infarct Progression', Brain and Behavior, 15, http://dx.doi.org/10.1002/brb3.70347

Garcia-Esperon C; Berry-Noronha A; Di Bartolo A; Green DS; Hasnain MG; Sharma GJ; Coutinho JM; Planken RN; Rinkel LA; Nio SS; Lim A; Kim J; Chew BLA; Leung M; Al-Hadethi S; Lin L; Levi CR; Spratt NJ; Wu T; Parsons MW, 2025, 'Arterial Input Function Dispersal on Acute Brain CT Perfusion Scan in Patients With Acute Stroke and an Intracardiac Thrombus', Neurology, 104, pp. e210256, http://dx.doi.org/10.1212/WNL.0000000000210256

Cheng X; Hong L; Lin L; Churilov L; Ling Y; Yang N; Fu J; Lu G; Yue Y; Zhang J; Wang F; Wang Z; Zhao Y; Zhou X; Peng Z; Wu D; Zhao L; Zhai Q; Yu X; Fang Q; Shao X; Tang Y; Zhang D; Geng Y; Zhang Y; Fan B; Zhang B; Yin C; Chen Y; Zhang Y; Liu X; Li S; Yang L; Parsons M; Dong Q; Xu J; Xie S; Liu C; Han D; Levi CR; Wang D; Holiday E; Cao W; Fang K; Dong Y; Ge L; Guo Y; Wang D; Xiao C; Li D; Feng J; Luo Z; Yang W; Chen L; Cao L; Zhao Y; Deng J; Li D; Te R; Jiang Z; Ye G; Zhu F; Pan Y; Chaoge A; Qi Z; Li X; Yu L; Tian X; Kang L; Wang J; Shen Y; Dai J; Li X; Zhang Y; Bai J; Li N; Su Y; Yao L; Jia Q; Guo L; Li Y; Sang H; Zhao L; Lu Y; Zhu C; Hu L; Li Y; Liu L; Zhu X; Xu S; Kong Y; Yao Z; Xu H; Zhang X; Xue J; Ma Y; Chen S; Wan Z; Ding Y; Li Z, 2025, 'Tenecteplase Thrombolysis for Stroke up to 24 Hours After Onset With Perfusion Imaging Selection: The CHABLIS-T II Randomized Clinical Trial', Stroke, 56, pp. 344 - 354, http://dx.doi.org/10.1161/STROKEAHA.124.048375

Li X; Wei C; Wu Y; Gao X; Sun J; Xu T; Chen C; Yang Q; Parsons MW; Huang Y; Yang J; Lin L, 2025, 'Perfusion Image-Aided Treatment Decision for Acute Ischemic Stroke: Validation of a Clinical Decision Support System', Cerebrovascular Diseases, http://dx.doi.org/10.1159/000543142

Hong L; Lin L; Ling Y; Liu X; Li S; YANG L; Wang X; HE Z; Zhang A; Cao N; Parsons M; Cheng X; Dong Q, 2025, 'Abstract TP1: The Association Between Time and Reperfusion in Acute Ischemic Stroke Patients With Large Vessel Occlusion Treated With Tenecteplase in an Extended Time Window: A Post-hoc Analysis of the Chablis-T Trials', Stroke, 56, http://dx.doi.org/10.1161/str.56.suppl_1.tp1

Xu T; Chen C; Yogendrakumar V; Cordato DJ; Blair C; Pham T; Cheung AK; Manning NW; Parsons MW; Lin L, 2025, 'Intra-Arterial Thrombolysis After Successful Thrombectomy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials', STROKE-VASCULAR AND INTERVENTIONAL NEUROLOGY, 5, http://dx.doi.org/10.1161/SVIN.125.001847

Cheng X; Hong L; Lin L; Churilov L; Ling Y; Zhang Y; Yang L; Parsons M; Dong Q, 2024, 'CHinese Acute Tissue-Based Imaging Selection for Lysis in Stroke Tenecteplase II (CHABLIS-T II): Rationale and design', Stroke and Vascular Neurology, 9, pp. 708 - 714, http://dx.doi.org/10.1136/svn-2023-002890

Lin L; Wang Y; Chen C; Bivard A; Butcher K; Garcia-Esperon C; Spratt NJ; Levi CR; Cheng X; Dong Q; Parsons MW, 2024, 'Exploring ischemic core growth rate and endovascular therapy benefit in large core patients', Journal of Cerebral Blood Flow and Metabolism, 44, pp. 1593 - 1604, http://dx.doi.org/10.1177/0271678X241242911

Deng J; He G; Yi T; Wei L; Lu H; Zhou Q; Yao Y; Zhu C; Levitt MR; Mossa-Basha M; Yang H; Shen Y; Shi F; Wang D; Lin L; Parsons M; Chen W; Zhu Y, 2024, 'Neuroprotective Effects of Rapid Local Ischemic Postconditioning in Successful Endovascular Thrombectomy Patients', Stroke, 55, pp. 2896 - 2900, http://dx.doi.org/10.1161/STROKEAHA.124.047674

Cheng X; Hong L; Churilov L; Lin L; Ling Y; Zhang J; Yang J; Geng Y; Wu D; Liu X; Zhou X; Zhao Y; Zhai Q; Zhao L; Chen Y; Guo Y; Yu X; Gong F; Sui Y; Li G; Yang L; Gu HQ; Wang Y; Parsons M; Dong Q, 2024, 'Tenecteplase thrombolysis for stroke up to 24 hours after onset with perfusion imaging selection: The umbrella phase IIa CHABLIS-T randomised clinical trial', Stroke and Vascular Neurology, 9, pp. 551 - 559, http://dx.doi.org/10.1136/svn-2023-002820

Tomari S; Lillicrap T; Garcia-Esperon C; Kashida YT; Bivard A; Lin L; Levi CR; Spratt NJ, 2024, 'Collateral assessment on magnetic resonance imaging/angiography up to 30 hours after stroke onset', Plos One, 19, http://dx.doi.org/10.1371/journal.pone.0309779

Yogendrakumar V; Lin L; Medcalf RL; Parsons MW, 2024, 'Improving thrombolysis efficiency for acute ischaemic stroke', Lancet Neurology, 23, pp. 853 - 855, http://dx.doi.org/10.1016/S1474-4422(24)00318-1

Parsons MW; Yogendrakumar V; Churilov L; Garcia-Esperon C; Campbell BCV; Russell ML; Sharma G; Chen C; Lin L; Chew BL; Ng FC; Deepak A; Choi PMC; Kleinig TJ; Cordato DJ; Wu TY; Fink JN; Ma H; Phan TG; Markus HS; Molina CA; Tsai CH; Lee JT; Jeng JS; Strbian D; Meretoja A; Arenillas JF; Buck BH; Devlin MJ; Brown H; Butcher KS; O'Brien B; Sabet A; Wijeratne T; Bivard A; Grimley RS; Agarwal S; Munshi SK; Donnan GA; Davis SM; Miteff F; Spratt NJ; Levi CR; Phan T; Selmes C; Lees K; Kaste M; MacIsaac R; Wellings T; Loiselle A; Pepper E; Krishnamurthy V; Ang T; Alanati K; Gangadharan S; Zareie H; Starling R; Dunkerton S; He J; Datta R; Royan A; Kerr E; Kaauwai L; Belevski L; Ormond S; Johnson A; Evans M; Lachapelle N; Ombelet F; Bladin C; Dewey H; Wong J; Park P; Cody R; Tan P; Callaly E; Senanayake C; Thomas G; Liu J; Busch T; Stuart N; Chung M; Yassi N; Valente M; Sharobeam A; Cooley R; Zhao H; Alemseged F; Williams C; Ng JL; Balabanski A; dos Santos A; Williamson J; Pavlin-Premrl D; Beharry J; Ma M; Park A; Yan B; Hand P; Jackson D, 2024, 'Tenecteplase versus alteplase for thrombolysis in patients selected by use of perfusion imaging within 4·5 h of onset of ischaemic stroke (TASTE): a multicentre, randomised, controlled, phase 3 non-inferiority trial', Lancet Neurology, 23, pp. 775 - 786, http://dx.doi.org/10.1016/S1474-4422(24)00206-0

Cai X; Zhou D; Wang P; Zhang Z; Fan Y; Lin L; Geng Y; Mossa-Basha M; Zhu C; Zhang S, 2024, 'Precranial artery calcification burden: a potential indicator of the clinical outcome of reperfusion in patients with acute large artery occlusion', Journal of International Medical Research, 52, http://dx.doi.org/10.1177/03000605241260364

Alysha D; Blair C; Thomas P; Pham T; Nguyen T; Cordato TR; Badge H; Chappelow N; Lin L; Edwards L; Thomas J; Hodgkinson S; Cappelen-Smith C; McDougall A; Cordato DJ; Parsons M, 2024, 'Comparative Prevalence of Cerebrovascular Disease in Vietnamese Communities in South-Western Sydney', Journal of Cardiovascular Development and Disease, 11, http://dx.doi.org/10.3390/jcdd11060164

Li S; Hong L; Yang W; Liu X; Zhang Y; Ling Y; He Z; Wang X; Yue Y; Dong Q; Wang F; Cheng X, 2024, 'The benefit of favorable venous outflow profile is mediated through reduced microvascular dysfunction in acute ischemic stroke', European Stroke Journal, 9, pp. 432 - 440, http://dx.doi.org/10.1177/23969873231224573

Sui Y; Chen W; Chen C; Chang Y; Bivard A; Wang P; Geng Y; Parsons M; Lin L, 2024, 'CTP-Defined Large Core Is a Better Predictor of Poor Outcome for Endovascular Treatment Than ASPECTS-Defined Large Core', Stroke, 55, pp. 1227 - 1234, http://dx.doi.org/10.1161/STROKEAHA.123.045091

Wang H; Shen P; Yu X; Shang Y; Xu J; Chen X; Tan M; Lin L; Parsons M; Zhang S; Geng Y, 2024, 'Asymmetric deep cerebral venous filling predicts poor outcome of acute basilar artery occlusion after endovascular treatment', CNS Neuroscience and Therapeutics, 30, http://dx.doi.org/10.1111/cns.14513

Sun J; Werdiger F; Blair C; Chen C; Yang Q; Bivard A; Lin L; Parsons M, 2024, 'Automatic segmentation of hemorrhagic transformation on follow-up non-contrast CT after acute ischemic stroke', Frontiers in Neuroinformatics, 18, pp. 1382630, http://dx.doi.org/10.3389/fninf.2024.1382630

Li J; Yang J; Gao X; Han Q; Wu Y; Shang Q; Huang Y; Xu Y; Huang Y; Lin L, 2024, 'Clot patterns determined by DSA and CTA can help predict intracranial atherosclerotic stenosis in acute ischemic stroke patients', Frontiers in Neurology, 15, http://dx.doi.org/10.3389/fneur.2024.1395764

Jiang P; Zhang S; Yu W; Shi Z; Jiang X; Wang X; Lin L; Parsons M; Guo W, 2024, 'Late Endovascular Treatment for Ischemic Stroke with Moderate to Large Infarct Volume is Associated with a better Clinical Prognosis', Current Neurovascular Research, 21, pp. 564 - 573, http://dx.doi.org/10.2174/0115672026370829250108051837

Santos AD; Visser M; Lin L; Bivard A; Churilov L; Parsons MW, 2024, 'Novel artificial intelligence-based hypodensity detection tool improves clinician identification of hypodensity on non-contrast computed tomography in stroke patients', Frontiers in Neurology, 15, http://dx.doi.org/10.3389/fneur.2024.1359775

Hong L; Lin L; Chen C; Bivard A; Levi CR; Su Y; Ling Y; Parsons MW; Cheng X; Dong Q, 2024, 'Abstract TMP54: Persistent Penumbral Profiles Indicate a Potentially Good Outcome in Acute Stroke Patients Without Major Reperfusion', Stroke, 55, http://dx.doi.org/10.1161/str.55.suppl_1.tmp54

Werdiger F; Visser M; Chen C; Lam C; Kolacz J; Parsons MW; Lin L; Levi C; Bivard A, 2024, 'Deep Learning-Based Prediction of Final Infarct Core from CT Perfusion Data: A Comparison to the Clinical Standard', STROKE-VASCULAR AND INTERVENTIONAL NEUROLOGY, 4, http://dx.doi.org/10.1161/SVIN.124.001375

Yang J; Wu Y; Gao X; Shang Q; Xu Y; Han Q; Li J; Chen C; Bivard A; Parsons MW; Lin L, 2023, 'Poor collateral flow with severe hypoperfusion explains worse outcome in acute stroke patients with atrial fibrillation', International Journal of Stroke, 18, pp. 689 - 696, http://dx.doi.org/10.1177/17474930221138707

Sharobeam A; Lin L; Lam C; Garcia-Esperon C; Gawarikar Y; Patel R; Lee-Archer M; Wong A; Roizman M; Gilligan A; Lee A; Tan KM; Day S; Levi C; Davis SM; Parsons M; Yan B, 2023, 'Early anticoagulation in patients with stroke and atrial fibrillation is associated with fewer ischaemic lesions at 1 month: the ATTUNE study', Stroke and Vascular Neurology, 9, pp. 30 - 37, http://dx.doi.org/10.1136/svn-2023-002357

Lin L; Zhang H; Liu F; Chen C; Chen C; Bivard A; Parsons MW; Li G, 2023, 'Bridging Thrombolysis Before Endovascular Therapy in Stroke Patients With Faster Core Growth', Neurology, 100, pp. E2083 - E2092, http://dx.doi.org/10.1212/WNL.0000000000207154

Gao L; Moodie M; Levi C; Lin L; Cheng X; Kleinig T; Butcher K; Yan B; Bivard A; Parsons M, 2023, 'Modelling the Long-Term Health Outcome and Costs of Thrombectomy in Treating Stroke Patients with Large Ischaemic Core: Comparison between Clinical Trials and Real-World Data', Cerebrovascular Diseases, 52, pp. 137 - 144, http://dx.doi.org/10.1159/000525806

Hong L; Ling Y; Zhang Y; Yang L; Li S; Liu X; Dong Q; Cheng X, 2023, 'Reperfusion measurements, treatment time, and outcomes in patients receiving endovascular treatment within 24 hours of last known well', CNS Neuroscience and Therapeutics, 29, pp. 1067 - 1074, http://dx.doi.org/10.1111/cns.14080

Tomari S; Lillicrap T; Garcia-Esperon C; Kashida YT; Bivard A; Lin L; Levi CR; Spratt NJ, 2023, 'Ischemic Lesion Growth in Patients with a Persistent Target Mismatch After Large Vessel Occlusion', Clinical Neuroradiology, 33, pp. 41 - 48, http://dx.doi.org/10.1007/s00062-022-01180-z

Edwards LS; Cappelen-Smith C; Cordato D; Bivard A; Churilov L; Lin L; Chen C; Garcia-Esperon C; Butcher K; Kleinig T; Choi PMC; Cheng X; Dong Q; Aviv RI; Parsons MW, 2023, 'Optimal CT perfusion thresholds for core and penumbra in acute posterior circulation infarction', Frontiers in Neurology, 14, http://dx.doi.org/10.3389/fneur.2023.1092505

Wang P; Chen W; Chen C; Bivard A; Yu G; Parsons MW; Lin L, 2023, 'Association of Perfusion Lesion Variables With Functional Outcome in Patients With Mild Stroke and Large Vessel Occlusion Managed Medically', Neurology, 100, pp. 627 - 638, http://dx.doi.org/10.1212/WNL.0000000000201498

Werdiger F; Parsons MW; Visser M; Levi C; Spratt N; Kleinig T; Lin L; Bivard A, 2023, 'Machine learning segmentation of core and penumbra from acute stroke CT perfusion data', Frontiers in Neurology, 14, http://dx.doi.org/10.3389/fneur.2023.1098562

Chen C; Yang J; Han Q; Wu Y; Li J; Xu T; Sun J; Gao X; Huang Y; Parsons MW; Lin L, 2023, 'Net water uptake within the ischemic penumbra predicts the presence of the midline shift in patients with acute ischemic stroke', Frontiers in Neurology, 14, http://dx.doi.org/10.3389/fneur.2023.1246775

Lin L; Blair C; Fu J; Cordato D; Cappelen-Smith C; Cheung A; Manning NW; Wenderoth J; Chen C; Bivard A; Butcher K; Kleinig TJ; Choi P; Levi CR; Parsons M, 2023, 'Prior anticoagulation and bridging thrombolysis improve outcomes in patients with atrial fibrillation undergoing endovascular thrombectomy for anterior circulation stroke', Journal of Neurointerventional Surgery, http://dx.doi.org/10.1136/jnis-2022-019560

Xu Y; Yang J; Gao X; Sun J; Shang Q; Han Q; Wu Y; Li J; Xu T; Huang Y; Pan Y; Parson MW; Lin L, 2023, 'Quantitative assessment of collateral time on perfusion computed tomography in acute ischemic stroke patients', Frontiers in Neurology, 14, http://dx.doi.org/10.3389/fneur.2023.1230697

Sun J; Lam C; Christie L; Blair C; Li X; Werdiger F; Yang Q; Bivard A; Lin L; Parsons M, 2023, 'Risk factors of hemorrhagic transformation in acute ischaemic stroke: A systematic review and meta-analysis', Frontiers in Neurology, 14, pp. 1079205, http://dx.doi.org/10.3389/fneur.2023.1079205

Cordato D; Blair C; Thomas P; Firtko A; Miller M; Edwards LS; Thomas J; Balabanski AH; Dos Santos A; Lin L; Hodgkinson S; Cappelen-Smith C; Beran RG; McDougall A; Parsons M, 2022, 'Cerebrovascular Disease Profiles of Culturally and Linguistically Diverse Communities in South Western Sydney and New South Wales', Cerebrovascular Diseases, 51, pp. 744 - 754, http://dx.doi.org/10.1159/000524242

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