By Dr Paul Baldock

Book Chapters

Ochi H; Baldock P; Takeda S, 2018, 'Central neuronal control of bone remodeling', in Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Wiley, pp. 1020 - 1027, http://dx.doi.org/10.1002/9781119266594.ch131

Kulkarni RN; Baldock PA, 2017, 'Bone and the central nervous system', in Molecular and Integrative Toxicology, pp. 399 - 416, http://dx.doi.org/10.1007/978-3-319-56192-9_13

Wee NKY; Herzog H; Baldock PA, 2016, 'Diet-induced obesity alters skeletal micro-architecture and the endocrine activity of bone', in Watson RR; Mahadevan D (ed.), HANDBOOK OF NUTRITION AND DIET IN THERAPY OF BONE DISEASES, WAGENINGEN ACAD PUBL, pp. 375 - 393, http://dx.doi.org/10.3920/978-90-8686-823-0_18

Wee NKY; Baldock PA, 2014, 'The skeletal effects of leptin', in Leptin: Biosynthesis, Functions and Clinical Significance, pp. 129 - 140

Takeda S; Baldock P, 2013, 'Central Neuronal Control of Bone Remodeling', in Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism: Eighth Edition, pp. 961 - 968, http://dx.doi.org/10.1002/9781118453926.ch115

Baldock PA, 2013, 'Chapter 4 Neuropeptide Y and Bone Formation', in Translational Endocrinology of Bone, Elsevier, pp. 39 - 49, http://dx.doi.org/10.1016/b978-0-12-415784-2.00004-x

Baldock P, 2013, 'Chapter 6 Neuropeptide Y and Bone Regulation', in Genetics of Bone Biology and Skeletal Disease, Elsevier, pp. 81 - 89, http://dx.doi.org/10.1016/b978-0-12-387829-8.00006-8

Baldock PA, 2012, 'Neuropeptide Y and Bone Formation', in Translational Endocrinology of Bone: Reproduction, Metabolism, and the Central Nervous System, pp. 39 - 49, http://dx.doi.org/10.1016/B978-0-12-415784-2.00004-X

Baldock PA; Allison SJ; Herzog H; Gardiner EM, 2006, 'The Central Control of Bone Remodeling', in Dynamics of Bone and Cartilage Metabolism: Principles and Clinical Applications, pp. 361 - 376, http://dx.doi.org/10.1016/B978-012088562-6/50022-4

Baldock PA; Allison SJ; Herzog H; Gardiner EM, 2006, 'Chapter 21 The Central Control of Bone Remodeling', in Dynamics of Bone and Cartilage Metabolism, Elsevier, pp. 361 - v, http://dx.doi.org/10.1016/b978-012088562-6/50022-4

Journal articles

Brzozowska MM; Isaacs M; Bliuc D; Baldock PA; Eisman JA; White CP; Greenfield JR; Center JR, 2023, 'Effects of bariatric surgery and dietary intervention on insulin resistance and appetite hormones over a 3 year period', Scientific Reports, 13, http://dx.doi.org/10.1038/s41598-023-33317-6

Diamond TH; Bryant C; Quinn R; Mohanty ST; Bonar F; Baldock PA; McDonald MM, 2023, 'Increased Bone Formation and Accelerated Bone Mass Accrual in a Man Presenting with Diffuse Osteosclerosis/High Bone Mass Phenotype and Adenocarcinoma of Unknown Primary', JBMR Plus, 7, http://dx.doi.org/10.1002/jbm4.10734

O'Donohue AK; Xiao Y; Lee LR; Schofield T; Cheng TL; Munns CF; Baldock PA; Schindeler A, 2023, 'Targeted postnatal knockout of Sclerostin using a bone-targeted adeno-associated viral vector increases bone anabolism and decreases canalicular density', Bone, 167, http://dx.doi.org/10.1016/j.bone.2022.116636

Brzozowska M; Isaacs M; Bliuc D; Baldock P; Eisman J; White C; Greenfield J; Center J, 2022, 'Effects of bariatric surgery and dietary intervention on changes in insulin resistance and appetite hormones over the period of 3 years', Endocrine Abstracts, http://dx.doi.org/10.1530/endoabs.81.rc5.6

Youlten SE; Kemp JP; Logan JG; Ghirardello EJ; Sergio CM; Dack MRG; Guilfoyle SE; Leitch VD; Butterfield NC; Komla-Ebri D; Chai RC; Corr AP; Smith JT; Mohanty ST; Morris JA; McDonald MM; Quinn JMW; McGlade AR; Bartonicek N; Jansson M; Hatzikotoulas K; Irving MD; Beleza-Meireles A; Rivadeneira F; Duncan E; Richards JB; Adams DJ; Lelliott CJ; Brink R; Phan TG; Eisman JA; Evans DM; Zeggini E; Baldock PA; Bassett JHD; Williams GR; Croucher PI, 2021, 'Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease', Nature Communications, 12, pp. 2444, http://dx.doi.org/10.1038/s41467-021-22517-1

Tangseefa P; Martin SK; Chin PY; Breen J; Mah CY; Baldock PA; Wittert GA; Page AJ; Proud CG; Fitter S; Zannettino ACW, 2021, 'The mTORC1 complex in pre-osteoblasts regulates whole-body energy metabolism independently of osteocalcin', Bone Research, 9, http://dx.doi.org/10.1038/s41413-020-00123-z

McDonald MM; Khoo WH; Ng PY; Xiao Y; Zamerli J; Thatcher P; Kyaw W; Pathmanandavel K; Grootveld AK; Moran I; Butt D; Nguyen A; Corr A; Warren S; Biro M; Butterfield NC; Guilfoyle SE; Komla-Ebri D; Dack MRG; Dewhurst HF; Logan JG; Li Y; Mohanty ST; Byrne N; Terry RL; Simic MK; Chai R; Quinn JMW; Youlten SE; Pettitt JA; Abi-Hanna D; Jain R; Weninger W; Lundberg M; Sun S; Ebetino FH; Timpson P; Lee WM; Baldock PA; Rogers MJ; Brink R; Williams GR; Bassett JHD; Kemp JP; Pavlos NJ; Croucher PI; Phan TG, 2021, 'Erratum: Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption (Cell (2021) 184(5) (1330–1347.e13), (S0092867421001525), (10.1016/j.cell.2021.02.002))', Cell, 184, pp. 1940, http://dx.doi.org/10.1016/j.cell.2021.03.010

McDonald MM; Khoo WH; Ng PY; Xiao Y; Zamerli J; Thatcher P; Kyaw W; Pathmanandavel K; Grootveld AK; Moran I; Butt D; Nguyen A; Warren S; Biro M; Butterfield NC; Guilfoyle SE; Komla-Ebri D; Dack MRG; Dewhurst HF; Logan JG; Li Y; Mohanty ST; Byrne N; Terry RL; Simic MK; Chai R; Quinn JMW; Youlten SE; Pettitt JA; Abi-Hanna D; Jain R; Weninger W; Lundberg M; Sun S; Ebetino FH; Timpson P; Lee WM; Baldock PA; Rogers MJ; Brink R; Williams GR; Bassett JHD; Kemp JP; Pavlos NJ; Croucher PI; Phan TG; Corr A, 2021, 'Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption', Cell, 184, pp. 1330 - 1347.e13, http://dx.doi.org/10.1016/j.cell.2021.02.002

Brzozowska MM; Tran T; Bliuc D; Jorgensen J; Talbot M; Fenton-Lee D; Chen W; Hong A; Viardot A; White CP; Nguyen TV; Pocock N; Eisman JA; Baldock PA; Center JR, 2021, 'Roux-en-Y gastric bypass and gastric sleeve surgery result in long term bone loss', International Journal of Obesity, 45, pp. 235 - 246, http://dx.doi.org/10.1038/s41366-020-00660-x

Wee NKY; Nguyen AD; Enriquez RF; Zhang L; Herzog H; Baldock PA, 2020, 'Neuropeptide Y Regulation of Energy Partitioning and Bone Mass During Cold Exposure', Calcified Tissue International, 107, pp. 510 - 523, http://dx.doi.org/10.1007/s00223-020-00745-9

Lee NJ; Qi Y; Enriquez RF; Clarke I; Ip CK; Wee N; Baldock PA; Herzog H, 2020, 'Energy partitioning between fat and bone mass is controlled via a hypothalamic leptin/NPY relay', International Journal of Obesity, 44, pp. 2149 - 2164, http://dx.doi.org/10.1038/s41366-020-0550-6

O'Brien EA; Ensbey KS; Day BW; Baldock PA; Barry G, 2020, 'Direct evidence for transport of RNA from the mouse brain to the germline and offspring', BMC Biology, 18, http://dx.doi.org/10.1186/s12915-020-00780-w

Findeisen M; Allen TL; Henstridge DC; Kammoun H; Brandon AE; Baggio LL; Watt KI; Pal M; Cron L; Estevez E; Yang C; Kowalski GM; O’Reilly L; Egan C; Sun E; Thai LM; Krippner G; Adams TE; Lee RS; Grötzinger J; Garbers C; Risis S; Kraakman MJ; Mellet NA; Sligar J; Kimber ET; Young RL; Cowley MA; Bruce CR; Meikle PJ; Baldock PA; Gregorevic P; Biden TJ; Cooney GJ; Keating DJ; Drucker DJ; Rose-John S; Febbraio MA, 2019, 'Treatment of type 2 diabetes with the designer cytokine IC7Fc', Nature, 574, pp. 63 - 68, http://dx.doi.org/10.1038/s41586-019-1601-9

Youlten SE; Baldock PA, 2019, 'Using mouse genetics to understand human skeletal disease', Bone, 126, pp. 27 - 36, http://dx.doi.org/10.1016/j.bone.2019.02.015

Al-Sharea A; Lee MKS; Dragoljevic D; Flynn M; Frings-Meuthen P; Kraakman M; Pernes G; Nagareddy P; Naik S; Hamilton J; Bobik A; Purton L; Baldock P; Masters S; Murphy A, 2019, 'A HIGH SALT DIET ACCELERATES ATHEROSCLEROSIS BY MODULATING HEMATOPOIESIS', ATHEROSCLEROSIS, 287, pp. E22 - E22, http://dx.doi.org/10.1016/j.atherosclerosis.2019.06.064

Morris JA; Kemp JP; Youlten SE; Laurent L; Logan JG; Chai RC; Vulpescu NA; Forgetta V; Kleinman A; Mohanty ST; Sergio CM; Quinn J; Nguyen-Yamamoto L; Luco AL; Vijay J; Simon MM; Pramatarova A; Medina-Gomez C; Trajanoska K; Ghirardello EJ; Butterfield NC; Curry KF; Leitch VD; Sparkes PC; Adoum AT; Mannan NS; Komla-Ebri DSK; Pollard AS; Dewhurst HF; Hassall TAD; Beltejar MJG; Agee M; Alipanahi B; Auton A; Bell RK; Bryc K; Elson SL; Fontanillas P; Furlotte NA; McCreight JC; Huber KE; Litterman NK; McIntyre MH; Mountain JL; Noblin ES; Northover CAM; Pitts SJ; Sathirapongsasuti JF; Sazonova OV; Shelton JF; Shringarpure S; Tian C; Tung JY; Vacic V; Wilson CH; Adams DJ; Vaillancourt SM; Kaptoge S; Baldock P; Cooper C; Reeve J; Ntzani EE; Evangelou E; Ohlsson C; Karasik D; Rivadeneira F; Kiel DP; Tobias JH; Gregson CL; Harvey NC; Grundberg E; Goltzman D; Adams DJ; Lelliott CJ; Hinds DA; Ackert-Bicknell CL; Hsu YH; Maurano MT; Croucher PI; Williams GR; Bassett JHD; Evans DM; Richards JB, 2019, 'Author Correction: An atlas of genetic influences on osteoporosis in humans and mice (Nature Genetics, (2019), 51, 2, (258-266), 10.1038/s41588-018-0302-x)', Nature Genetics, 51, pp. 920, http://dx.doi.org/10.1038/s41588-019-0415-x

Morris JA; Kemp JP; Youlten SE; Laurent L; Logan JG; Chai RC; Vulpescu NA; Forgetta V; Kleinman A; Mohanty ST; Sergio CM; Quinn J; Nguyen-Yamamoto L; Luco AL; Vijay J; Simon MM; Pramatarova A; Medina-Gomez C; Trajanoska K; Ghirardello EJ; Butterfield NC; Curry KF; Leitch VD; Sparkes PC; Adoum AT; Mannan NS; Komla-Ebri DSK; Pollard AS; Dewhurst HF; Hassall TAD; Beltejar MJG; Agee M; Alipanahi B; Auton A; Bell RK; Bryc K; Elson SL; Fontanillas P; Furlotte NA; McCreight JC; Huber KE; Litterman NK; McIntyre MH; Mountain JL; Noblin ES; Northover CAM; Pitts SJ; Sathirapongsasuti JF; Sazonova OV; Shelton JF; Shringarpure S; Tian C; Tung JY; Vacic V; Wilson CH; Adams DJ; Vaillancourt SM; Kaptoge S; Baldock P; Cooper C; Reeve J; Ntzani EE; Evangelou E; Ohlsson C; Karasik D; Rivadeneira F; Kiel DP; Tobias JH; Gregson CL; Harvey NC; Grundberg E; Goltzman D; Adams DJ; Lelliott CJ; Hinds DA; Ackert-Bicknell CL; Hsu YH; Maurano MT; Croucher PI; Williams GR; Bassett JHD; Evans DM; Richards JB, 2019, 'An atlas of genetic influences on osteoporosis in humans and mice', Nature Genetics, 51, pp. 258 - 266, http://dx.doi.org/10.1038/s41588-018-0302-x

Lee NJ; Clarke IM; Zengin A; Enriquez RF; Nagy V; Penninger JM; Baldock PA; Herzog H, 2019, 'RANK deletion in neuropeptide Y neurones attenuates oestrogen deficiency-related bone loss', Journal of Neuroendocrinology, 31, http://dx.doi.org/10.1111/jne.12687

Lee NJ; Ali N; Zhang L; Qi Y; Clarke I; Enriquez RF; Brzozowska M; Lee IC; Rogers MJ; Laybutt DR; Center JR; Baldock PA; Herzog H, 2019, 'Osteoglycin, a novel coordinator of bone and glucose homeostasis', Obesity Research & Clinical Practice, 13, pp. 256 - 256, http://dx.doi.org/10.1016/j.orcp.2018.11.063

Zhang L; Ip CK; Lee ICJ; Qi Y; Reed F; Karl T; Low JK; Enriquez RF; Lee NJ; Baldock PA; Herzog H, 2018, 'Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling', Nature Communications, 9, http://dx.doi.org/10.1038/s41467-018-06462-0

Reid IR; Baldock PA; Cornish J, 2018, 'Effects of Leptin on the Skeleton', Endocrine Reviews, 39, pp. 938 - 959, http://dx.doi.org/10.1210/er.2017-00226

Wee NKY; Enriquez RF; Nguyen AD; Horsnell H; Kulkarni R; Khor EC; Herzog H; Baldock PA, 2018, 'Diet-induced obesity suppresses cortical bone accrual by a neuropeptide Y-dependent mechanism', International Journal of Obesity, 42, pp. 1925 - 1938, http://dx.doi.org/10.1038/s41366-018-0028-y

Sharma AK; Toussaint ND; Elder GJ; Rajapakse CS; Holt SG; Baldock P; Robertson PL; Ebeling PR; Sorci OR; Masterson R, 2018, 'Changes in bone microarchitecture following kidney transplantation—Beyond bone mineral density', Clinical Transplantation, 32, http://dx.doi.org/10.1111/ctr.13347

Sharma AK; Toussaint ND; Elder GJ; Masterson R; Holt SG; Robertson PL; Ebeling PR; Baldock P; Miller RC; Rajapakse CS, 2018, 'Magnetic resonance imaging based assessment of bone microstructure as a non-invasive alternative to histomorphometry in patients with chronic kidney disease', Bone, 114, pp. 14 - 21, http://dx.doi.org/10.1016/j.bone.2018.05.029

Sharma AK; Toussaint ND; Masterson R; Holt SG; Rajapakse CS; Ebeling PR; Mohanty ST; Baldock P; Elder GJ, 2018, 'Deterioration of Cortical Bone Microarchitecture: Critical Component of Renal Osteodystrophy Evaluation', American Journal of Nephrology, 47, pp. 376 - 384, http://dx.doi.org/10.1159/000489671

Lee NJ; Ali N; Qi J; Clarke RF; Enriquez RF; Brzozowska M; Lee IC; Rogers MJ; Laybutt DR; Center JR; Baldock PA; Herzog H, 2018, 'Osteoglycin, an Osteoblast-derived Regulator of Bone Mass and Glucose Homeostasis', Molecular Metabolism, http://dx.doi.org/10.1016/j.molmet.2018.05.004

Tangseefa P; Martin SK; Fitter S; Baldock PA; Proud CG; Zannettino ACW, 2018, 'Osteocalcin-dependent regulation of glucose metabolism and fertility: Skeletal implications for the development of insulin resistance', Journal of Cellular Physiology, 233, pp. 3769 - 3783, http://dx.doi.org/10.1002/jcp.26163

Lee NJ; Clarke IM; Enriquez RF; Nagy V; Penninger J; Baldock PA; Herzog H, 2018, 'Central RANK signalling in NPY neurons alters bone mass in male mice', Neuropeptides, 68, pp. 75 - 83, http://dx.doi.org/10.1016/j.npep.2018.02.004

Burchfield JG; Kebede MA; Meoli CC; Stöckli J; Whitworth PT; Wright AL; Hoffman NJ; Minard AY; Ma X; Krycer JR; Nelson ME; Tan SX; Yau B; Thomas KC; Wee NKY; Khor EC; Enriquez RF; Vissel B; Biden TJ; Baldock PA; Hoehn KL; Cantley J; Cooney GJ; James DE; Fazakerley DJ; Wright A, 2018, 'High dietary fat and sucrose results in an extensive and time-dependent deterioration in health of multiple physiological systems in mice', Journal of Biological Chemistry, 293, pp. 5731 - 5745, http://dx.doi.org/10.1074/jbc.RA117.000808

McDonald MM; Morse A; Schindeler A; Mikulec K; Peacock L; Cheng T; Bobyn J; Lee L; Baldock PA; Croucher PI; Tam PPL; Little DG, 2018, 'Homozygous Dkk1 Knockout Mice Exhibit High Bone Mass Phenotype Due to Increased Bone Formation', Calcified Tissue International, 102, pp. 105 - 116, http://dx.doi.org/10.1007/s00223-017-0338-4

Nguyen AD; Lee NJ; Wee NKY; Zhang L; Enriquez RF; Khor EC; Nie T; Wu D; Sainsbury A; Baldock PA; Herzog H, 2018, 'Uncoupling protein-1 is protective of bone mass under mild cold stress conditions', Bone, 106, pp. 167 - 178, http://dx.doi.org/10.1016/j.bone.2015.05.037

Loh K; Zhang L; Brandon A; Wang Q; Begg D; Qi Y; Fu M; Kulkarni R; Teo J; Baldock P; Bruning JC; Cooney G; Neely GG; Herzog H, 2017, 'Corrigendum to “Insulin controls food intake and energy balance via NPY neurons” [Mol Metabol 6 (2017) 574–584], (S2212877817301552), (10.1016/j.molmet.2017.03.013))', Molecular Metabolism, 6, pp. 1562, http://dx.doi.org/10.1016/j.molmet.2017.06.017

Nobis M; Herrmann D; Warren SC; Kadir S; Leung W; Killen M; Magenau A; Stevenson D; Lucas MC; Reischmann N; Vennin C; Conway JRW; Boulghourjian A; Zaratzian A; Law AM; Gallego-Ortega D; Ormandy CJ; Walters SN; Grey ST; Bailey J; Chtanova T; Quinn JMW; Baldock PA; Croucher PI; Schwarz JP; Mrowinska A; Zhang L; Herzog H; Masedunskas A; Hardeman EC; Gunning PW; del Monte-Nieto G; Harvey RP; Samuel MS; Pajic M; McGhee EJ; Johnsson AKE; Sansom OJ; Welch HCE; Morton JP; Strathdee D; Anderson KI; Timpson P; del Monte Nieto G, 2017, 'A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts', Cell Reports, 21, pp. 274 - 288, http://dx.doi.org/10.1016/j.celrep.2017.09.022

Corr A; Smith J; Baldock P, 2017, 'Neuronal Control of Bone Remodeling', Toxicologic Pathology, 45, pp. 894 - 903, http://dx.doi.org/10.1177/0192623317738708

McDonald MM; Reagan MR; Youlten SE; Mohanty ST; Seckinger A; Terry RL; Pettitt JA; Simic MK; Cheng TL; Morse A; Le LMT; Abi-Hanna D; Kramer I; Falank C; Fairfield H; Ghobrial IM; Baldock PA; Little DG; Kneissel M; Vanderkerken K; Bassett JHD; Williams GR; Oyajobi BO; Hose D; Phan TG; Croucher PI, 2017, 'Inhibiting the osteocyte-specific protein sclerostin increases bone mass and fracture resistance in multiple myeloma', Blood, 129, pp. 3452 - 3464, http://dx.doi.org/10.1182/blood-2017-03-773341

Loh K; Zhang L; Brandon A; Wang Q; Begg D; Qi Y; Fu M; Kulkarni R; Teo J; Baldock P; Brüning JC; Cooney G; Neely G; Herzog H, 2017, 'Insulin controls food intake and energy balance via NPY neurons', Molecular Metabolism, 6, pp. 574 - 584, http://dx.doi.org/10.1016/j.molmet.2017.03.013

Kulkarni R; Schindeler A; Croucher P; Little D; Baldock P, 2016, 'Is circulating sclerostin an endocrine modulator of bone mass?', Bone Abstracts, http://dx.doi.org/10.1530/boneabs.5.oc2.5

Horsnell H; Wee N; Kulkarni R; Herzog H; Baldock P, 2016, 'Osteocalcin transgenic mice reveal aspects of the bone/glucose axis, as well as powerful suppression of ectopic osteocalcin protein production', Bone Abstracts, http://dx.doi.org/10.1530/boneabs.5.p231

Horsnell H; Wee N; Kulkarni R; Herzog H; Baldock P, 2016, 'Osteocalcin transgenic mice reveal aspects of the bone/glucose axis, as well as powerful suppression of ectopic osteocalcin protein production', Bone Abstracts, http://dx.doi.org/10.1530/boneabs.5.op18

Khor EC; Yulyaningsih E; Driessler F; Kovaĉić N; Wee NKY; Kulkarni RN; Lee NJ; Enriquez RF; Xu J; Zhang L; Herzog H; Baldock PA, 2016, 'The y6 receptor suppresses bone resorption and stimulates bone formation in mice via a suprachiasmatic nucleus relay', Bone, 84, pp. 139 - 147, http://dx.doi.org/10.1016/j.bone.2015.12.011

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