By Dr Peter Alan Simmons

Journal articles

Downie LE; Hom MM; Berdy GJ; El-Harazi S; Verachtert A; Tan J; Liu H; Carlisle-Wilcox C; Simmons P; Vehige J, 2020, 'An artificial tear containing flaxseed oil for treating dry eye disease: A randomized controlled trial', Ocular Surface, 18, pp. 148 - 157, http://dx.doi.org/10.1016/j.jtos.2019.11.004

Aragona P; Simmons PA; Wang H; Wang T, 2019, 'Physicochemical properties of hyaluronic acid–based lubricant eye drops', Translational Vision Science and Technology, 8, http://dx.doi.org/10.1167/tvst.8.6.2

Lievens C; Berdy G; Douglass D; Montaquila S; Lin H; Simmons P; Carlisle-Wilcox C; Vehige J; Haque S, 2019, 'Evaluation of an enhanced viscosity artificial tear for moderate to severe dry eye disease: A multicenter, double-masked, randomized 30-day study.', Cont Lens Anterior Eye, 42, pp. 443 - 449, http://dx.doi.org/10.1016/j.clae.2018.12.003

Martin E; Oliver KM; Pearce EI; Tomlinson A; Simmons P; Hagan S, 2018, 'Effect of tear supplements on signs, symptoms and inflammatory markers in dry eye.', Cytokine, 105, pp. 37 - 44, http://dx.doi.org/10.1016/j.cyto.2018.02.009

Wallerstein A; Jackson WB; Chambers J; Moezzi AM; Lin H; Simmons PA, 2018, 'Management of post-LASIK dry eye: a multicenter randomized comparison of a new multi-ingredient artificial tear to carboxymethylcellulose.', Clin Ophthalmol, 12, pp. 839 - 848, http://dx.doi.org/10.2147/OPTH.S163744

Simmons PA; Vehige JG, 2017, 'Investigating the potential benefits of a new artificial tear formulation combining two polymers.', Clin Ophthalmol, 11, pp. 1637 - 1642, http://dx.doi.org/10.2147/OPTH.S135550

Nichols JJ; Lievens CW; Bloomenstein MR; Liu H; Simmons P; Vehige J, 2016, 'Dual-Polymer Drops, Contact Lens Comfort, and Lid Wiper Epitheliopathy.', Optom Vis Sci, 93, pp. 979 - 986, http://dx.doi.org/10.1097/OPX.0000000000000878

Simmons PA; Carlisle-Wilcox C; Chen R; Liu H; Vehige JG, 2015, 'Efficacy, safety, and acceptability of a lipid-based artificial tear formulation: a randomized, controlled, multicenter clinical trial.', Clin Ther, 37, pp. 858 - 868, http://dx.doi.org/10.1016/j.clinthera.2015.01.001

Simmons P; Liu H; Chen R; Math FLM; Carlisle C; Vehige J, 2015, 'Clinical evaluation of a dual-polymer rewetting drop: Improved patient-reported outcomes and lid wiper epitheliopathy in contact lens wearers', Contact Lens and Anterior Eye, 38, pp. e33 - e33, http://dx.doi.org/10.1016/j.clae.2014.11.050

Simmons PA; Carlisle-Wilcox C; Vehige JG, 2015, 'Comparison of novel lipid-based eye drops with aqueous eye drops for dry eye: a multicenter, randomized controlled trial.', Clin Ophthalmol, 9, pp. 657 - 664, http://dx.doi.org/10.2147/OPTH.S74849

Simmons PA; Liu H; Carlisle-Wilcox C; Vehige JG, 2015, 'Efficacy and safety of two new formulations of artificial tears in subjects with dry eye disease: a 3-month, multicenter, active-controlled, randomized trial.', Clin Ophthalmol, 9, pp. 665 - 675, http://dx.doi.org/10.2147/OPTH.S78184

She Y; Li J; Xiao B; Lu H; Liu H; Simmons PA; Vehige JG; Chen W, 2015, 'Evaluation of a Novel Artificial Tear in the Prevention and Treatment of Dry Eye in an Animal Model.', J Ocul Pharmacol Ther, 31, pp. 525 - 530, http://dx.doi.org/10.1089/jop.2015.0042

Khandekar N; Willcox MDP; Shih S; Simmons P; Vehige J; Garrett Q, 2013, 'Decrease in hyperosmotic stress-induced corneal epithelial cell apoptosis by L-carnitine', Molecular Vision, 19, pp. 1945 - 1956

Garrett Q; Khandekar N; Shih S; Flanagan JL; Simmons P; Vehige J; Willcox MD, 2013, 'Betaine stabilizes cell volume and protects against apoptosis in human corneal epithelial cells under hyperosmotic stress', Experimental Eye Research, 108, pp. 33 - 41, http://dx.doi.org/10.1016/j.exer.2012.12.001

Madden LC; Tomlinson A; Simmons PA, 2013, 'Effect of humidity variations in a controlled environment chamber on tear evaporation after dry eye therapy.', Eye Contact Lens, 39, pp. 169 - 174, http://dx.doi.org/10.1097/ICL.0b013e318283dfc6

Guillon M; Maissa C; Wong S; Lane A; Simmons P; Vehige J, 2013, 'Effect of lipid-based eyedrops on silicone hydrogel contact lens wear subjective acceptance', Contact Lens and Anterior Eye, 36, pp. e43 - e43, http://dx.doi.org/10.1016/j.clae.2013.08.143

Tomlinson A; Madden LC; Simmons PA, 2013, 'Effectiveness of dry eye therapy under conditions of environmental stress.', Curr Eye Res, 38, pp. 229 - 236, http://dx.doi.org/10.3109/02713683.2012.757323

Maïssa C; Guillon M; Simmons P; Vehige J, 2010, 'Effect of castor oil emulsion eyedrops on tear film composition and stability.', Cont Lens Anterior Eye, 33, pp. 76 - 82, http://dx.doi.org/10.1016/j.clae.2009.10.005

Flanagan JL; Simmons P; Vehige J; Willcox MD; Garrett Q, 2010, 'Role of Carnitine in Disease', Nutrition and Metabolism, 7, pp. 30 - 40, http://dx.doi.org/10.1186/1743-7075-7-30

Xu S; Flanagan JL; Simmons P; Vehige J; Willcox MD; Garrett Q, 2010, 'Transport of L-carnitine in human corneal and conjunctival epithelial cells', Molecular Vision, 16, pp. 1823 - 1831

Garrett Q; Xu S; Simmons P; Vehige J; Xie RZ; Kumar A; Flanagan JL; Zhao Z; Willcox MD, 2008, 'Carboxymethyl cellulose stimulates rabbit corneal epithelial wound healing', Current Eye Research, 33, pp. 567 - 573

Wang J; Simmons P; Aquavella J; Vehige J; Palakuru J; Chung S; Feng C, 2008, 'Dynamic distribution of artificial tears on the ocular surface.', Arch Ophthalmol, 126, pp. 619 - 625, http://dx.doi.org/10.1001/archopht.126.5.619

Khanal S; Simmons PA; Pearce EI; Day M; Tomlinson A, 2008, 'Effect of artificial tears on tear stress test.', Optom Vis Sci, 85, pp. 732 - 739, http://dx.doi.org/10.1097/OPX.0b013e318181ae1c

Garrett Q; Xu S; Simmons P; Vehige J; Flanagan JL; Willcox MD, 2008, 'Expression and Localization of Carnitine/Organic Cation Transporter OCTN1 and OCTN2 in Ocular Epithelium', Investigative Ophthalmology and Visual Science, 49, pp. 4844 - 4849

Xu S; Garrett Q; Simmons P; Vehige J; Willcox M, 2008, 'Expression and Localization of Carnitine/Organic Cation Transporter OCTN1 and OCTN2 in Ocular Epithelium', Journal of Proteomics & Bioinformatics, S2, pp. 320 - 321, http://dx.doi.org/10.4172/jpb.s1000229

Paugh JR; Marsden HJ; Edrington TB; Deland PN; Simmons PA; Vehige JG, 2007, 'A pre-application drop containing carboxymethylcellulose can reduce multipurpose solution-induced corneal staining.', Optom Vis Sci, 84, pp. 65 - 71, http://dx.doi.org/10.1097/01.opx.0000254044.94356.23

Garrett Q; Simmons P; Xu S; Vehige J; Zhao ZJ; Ehrmann K; Willcox MD, 2007, 'Carboxymethylcellulose binds to human corneal epithelial cells and is a modulator of corneal epithelial wound healing', Investigative Ophthalmology and Visual Science, 48, pp. 1559 - 1567

Simmons PA; Vehige JG, 2007, 'Clinical performance of a mid-viscosity artificial tear for dry eye treatment.', Cornea, 26, pp. 294 - 302, http://dx.doi.org/10.1097/ICO.0b013e31802e1e04

Khanal S; Tomlinson A; Pearce EI; Simmons PA, 2007, 'Effect of an oil-in-water emulsion on the tear physiology of patients with mild to moderate dry eye.', Cornea, 26, pp. 175 - 181, http://dx.doi.org/10.1097/ICO.0b013e31802b492d

Brennan NA; Coles M-LC; Simmons PA; Vehige J, 2005, 'Evidence of Tear Thickness Changes Following Instillation of Tear Lubricants', The Ocular Surface, 3, pp. S49 - S49, http://dx.doi.org/10.1016/s1542-0124(12)70363-4

Coles M-LC; Brennan NA; Shuley V; Woods J; Prior C; Vehige JG; Simmons PA, 2004, 'The influence of lens conditioning on signs and symptoms with new hydrogel contact lenses.', Clin Exp Optom, 87, pp. 367 - 371, http://dx.doi.org/10.1111/j.1444-0938.2004.tb03096.x

Vehige JG; Simmons PA; Anger C; Graham R; Tran L; Brady N, 2003, 'Cytoprotective properties of carboxymethyl cellulose (CMC) when used prior to wearing contact lenses treated with cationic disinfecting agents.', Eye Contact Lens, 29, pp. 177 - 180, http://dx.doi.org/10.1097/01.ICL.0000074106.82322.17

Carlisle C; Felix C; Simmons P; Stoecker J; Vehige J, 2002, 'A NEW EMULSION-BASED DRY EYE TREATMENT: RESULTS OF A CONTROLLED CLINICAL TRIAL.', Optometry and Vision Science, 79, pp. 306 - 306, http://dx.doi.org/10.1097/00006324-200212001-00568

Thai LC; Tomlinson A; Simmons PA, 2002, 'In vitro and in vivo effects of a lubricant in a contact lens solution.', Ophthalmic Physiol Opt, 22, pp. 319 - 329, http://dx.doi.org/10.1046/j.1475-1313.2002.00042.x

Coles C; Brennan NA; Shuley V; Woods J; Hall M; Consultants B; Vehige J; Simmons P, 2002, 'THE INFLUENCE OF LENS CONDITIONING ON SIGNS AND SYMPTOMS WITH NEW HYDROGEL LENSES.', Optometry and Vision Science, 79, pp. 138 - 138, http://dx.doi.org/10.1097/00006324-200212001-00263

Simmons PA; Donshik PC; Kelly WF; Vehige JG, 2001, 'Conditioning of hydrogel lenses by a multipurpose solution containing an ocular lubricant.', CLAO J, 27, pp. 192 - 194, https://www.ncbi.nlm.nih.gov/pubmed/11725980

Tomlinson A; Pearce EI; Simmons PA; Blades K, 2001, 'Effect of oral contraceptives on tear physiology', Ophthalmic and Physiological Optics, 21, pp. 9 - 16, http://dx.doi.org/10.1046/j.1475-1313.2001.00544.x

Tomlinson A; Pearce EI; Simmons PA; Blades K, 2001, 'Effect of oral contraceptives on tear physiology.', Ophthalmic Physiol Opt, 21, pp. 9 - 16, https://www.ncbi.nlm.nih.gov/pubmed/11220045

Brennan N; Jaworski A; Shuley V; Coles C; Consultants B; Simmons P; Paugh J, 2001, 'STUDIES OF THE POST-LENS TEAR FILM.', Optometry and Vision Science, 78, pp. 51 - 51, http://dx.doi.org/10.1097/00006324-200112001-00050

Simmons PA; Prather W; Vehige J, 2000, '(CL-125)IMPROVEMENT IN WETTING PROPERTIES OF A MULTIPURPOSE CONTACT LENS SOLUTION BY ADDITION OF HYDROXYPROPYL METHYLCELLULOSE (HPMC)', Optometry and Vision Science, 77, pp. 178 - 178, http://dx.doi.org/10.1097/00006324-200012001-00293

Lamotte J; Bergamo N; Neunzig S; Simmons P, 2000, '(CL-168)ADHERENCE OF CYTOTOXIC PSEUDOMONAS AERUGINOSA TO UNWORN HYDROGEL LENSES', Optometry and Vision Science, 77, pp. 177 - 177, http://dx.doi.org/10.1097/00006324-200012001-00292

Simmons PA; Kelly W; Prather W; Vehige J, 2000, 'CLINICAL BENEFITS AND PHYSICAL PROPERTIES OF ADDITION OF HYDROXYPROPYL METHYLCELLULOSE (HPMC) TO A MULTI-PURPOSE CONTACT LENS CARE SOLUTION.', Cornea, 19, pp. S124 - S124, http://dx.doi.org/10.1097/00003226-200011002-00175

Tomlinson A; Simmons PA; Seal DV; McFadyen AK, 2000, 'Salicylate inhibition of Acanthamoeba attachment to contact lenses: a model to reduce risk of infection.', Ophthalmology, 107, pp. 112 - 117, http://dx.doi.org/10.1016/s0161-6420(99)00055-x

Simmons PA; Tomlinson A; Seal DV, 1998, 'The role of Pseudomonas aeruginosa biofilm in the attachment of Acanthamoeba to four types of hydrogel contact lens materials.', Optom Vis Sci, 75, pp. 860 - 866, http://dx.doi.org/10.1097/00006324-199812000-00007

Simmons PA; Edrington TB; Pfondevida CJ; Lee M; Wechsler S, 1996, 'Comparison between evening and morning surfactant cleaning of hydrogel lenses', International Contact Lens Clinic, 23, pp. 172 - 176, http://dx.doi.org/10.1016/s0892-8967(96)00085-5

Simmons PA; Tomlinson A; Connor R; Hay J; Seal DV, 1996, 'Effect of patient wear and extent of protein deposition on adsorption of Acanthamoeba to five types of hydrogel contact lenses.', Optom Vis Sci, 73, pp. 362 - 368, http://dx.doi.org/10.1097/00006324-199606000-00002

Simmons PA; Edrington TB; Lao KF; Concepcion LL, 1996, 'The efficacy of disinfection systems for in-office storage of hydrogel contact lenses', International Contact Lens Clinic, 23, pp. 94 - 98, http://dx.doi.org/10.1016/0892-8967(96)00029-6

Cook JN; Vehige JG; Simmons PA, 1995, 'COMPARATIVE PASSIVE CLE ANING ABILITY OF TWO MULTIPURPOSE CONTACT LENS CARE SOLUTIONS ON IN VITRO DEPOSITED AND HUMAN WORN SOFT CONTACT LENSES', Optometry and Vision Science, 72, pp. 151 - 151, http://dx.doi.org/10.1097/00006324-199512001-00254

Hay J; Seal DV; Connor R; Simmons PA; Tomlinson A, 1995, 'Disinfection and sonication: Effect on association of Acanthamoeba cysts with an ionic, high-water content hydrogel contact lens', Journal of The British Contact Lens Association, 18, pp. 5 - 8, http://dx.doi.org/10.1016/s0141-7037(95)80042-5

Simmons PA; Edrington TB; Lao KF; Le LT, 1995, 'EFFICACY OF DISINFECTION SYSTEMS FOR IN-OFFICE STORAGE OF HYDROGEL', Optometry and Vision Science, 72, pp. 150 - 150, http://dx.doi.org/10.1097/00006324-199512001-00252

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