Select Publications
Book Chapters
2018, 'Sex Chromosomes', in Skinner MK (ed.), Encyclopedia of Reproduction, Academic Press, pp. 238 - 244, http://dx.doi.org/10.1016/B978-0-12-801238-3.64459-8
,2010, 'Marsupial genetics reveals insights into evolution of mammalian X chromosome inactivation', in Marsupial Genetics and Genomics, pp. 259 - 280, http://dx.doi.org/10.1007/978-90-481-9023-2_13
,Journal articles
2024, 'Human Nasal Epithelium Organoids for Assessing Neutralizing Antibodies to a Protective SARS-CoV-2 Virus-like Particle Vaccine', Organoids, 3, pp. 18 - 31, http://dx.doi.org/10.3390/organoids3010002
,2023, 'Copper chelation suppresses epithelial-mesenchymal transition by inhibition of canonical and non-canonical TGF-β signaling pathways in cancer', Cell and Bioscience, 13, http://dx.doi.org/10.1186/s13578-023-01083-7
,2023, 'Hierarchical assembly of tryptophan zipper peptides into stress-relaxing bioactive hydrogels', Nature Communications, 14, http://dx.doi.org/10.1038/s41467-023-41907-1
,2023, 'Comparing Cytology Brushes for Optimal Human Nasal Epithelial Cell Collection: Implications for Airway Disease Diagnosis and Research', Journal of Personalized Medicine, 13, pp. 864, http://dx.doi.org/10.3390/jpm13050864
,2023, 'Gas-modulating microcapsules for spatiotemporal control of hypoxia', Proceedings of the National Academy of Sciences of the United States of America, 120, pp. e2217557120, http://dx.doi.org/10.1073/pnas.2217557120
,2023, 'Assessment of Pre-Clinical Liver Models Based on Their Ability to Predict the Liver-Tropism of Adeno-Associated Virus Vectors', Human Gene Therapy, 34, pp. 273 - 288, http://dx.doi.org/10.1089/hum.2022.188
,2023, 'Molecular and Functional Characteristics of Airway Epithelium under Chronic Hypoxia', International Journal of Molecular Sciences, 24, http://dx.doi.org/10.3390/ijms24076475
,2023, 'Q1291H-CFTR molecular dynamics simulations and ex vivo theratyping in nasal epithelial models and clinical response to elexacaftor/tezacaftor/ivacaftor in a Q1291H/F508del patient', Frontiers in Molecular Biosciences, 10, http://dx.doi.org/10.3389/fmolb.2023.1148501
,2023, 'WS14.02 Cystic fibrosis personalised medicine; paediatric in vitro airway cell models to predict CFTR modulator patient outcomes', Journal of Cystic Fibrosis, 22, pp. S28 - S28, http://dx.doi.org/10.1016/s1569-1993(23)00266-7
,2022, 'S945L-CFTR molecular dynamics, functional characterization and tezacaftor/ivacaftor efficacy in vivo and in vitro in matched pediatric patient-derived cell models', Frontiers in Pediatrics, 10, pp. 1062766, http://dx.doi.org/10.3389/fped.2022.1062766
,2022, 'Quantifying Intracellular Viral Pathogen: Specimen Preparation, Visualization and Quantification of Multiple Immunofluorescent Signals in Fixed Human Airway Epithelium Cultured at Air-Liquid Interface', Journal of Personalized Medicine, 12, http://dx.doi.org/10.3390/jpm12101668
,2022, 'Molecular Dynamics and Theratyping in Airway and Gut Organoids Reveal R352Q-CFTR Conductance Defect', American Journal of Respiratory Cell and Molecular Biology, 67, pp. 99 - 111, http://dx.doi.org/10.1165/rcmb.2021-0337OC
,2022, 'Computer modelling the root cause of cystic fibrosis', BIOPHYSICAL JOURNAL, 121, pp. 506A - 506A, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000759523003277&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2022, 'Molecular dynamics and functional characterization of I37R-CFTR lasso mutation provide insights into channel gating activity', iScience, 25, pp. 103710, http://dx.doi.org/10.1016/j.isci.2021.103710
,2022, 'Air-Liquid-Interface Differentiated Human Nose Epithelium: A Robust Primary Tissue Culture Model of SARS-CoV-2 Infection', International Journal of Molecular Sciences, 23, http://dx.doi.org/10.3390/ijms23020835
,2022, 'Leukocyte-specific DNA methylation biomarkers and their implication for pathological epigenetic analysis', Epigenetics Communications, 2, http://dx.doi.org/10.1186/s43682-022-00011-z
,2021, 'Multi-omics of the esophageal microenvironment identifies signatures associated with progression of Barrett’s esophagus', Genome Medicine, 13, pp. 133, http://dx.doi.org/10.1186/s13073-021-00951-6
,2021, 'Collection, Expansion, and Differentiation of Primary Human Nasal Epithelial Cell Models for Quantification of Cilia Beat Frequency', Journal of Visualized Experiments, http://dx.doi.org/10.3791/63090-v
,2021, 'Collection, expansion, and differentiation of primary human nasal epithelial cell models for quantification of cilia beat frequency', Journal of Visualized Experiments, http://dx.doi.org/10.3791/63090
,2021, 'Cystic fibrosis-related diabetes and lung disease: An update', European Respiratory Review, 30, pp. 200293, http://dx.doi.org/10.1183/16000617.0293-2020
,2021, 'Treatment of Cystic Fibrosis: From Gene- to Cell-Based Therapies', Frontiers in Pharmacology, 12, pp. 639475, http://dx.doi.org/10.3389/fphar.2021.639475
,2021, 'Significant functional differences in differentiated Conditionally Reprogrammed (CRC)- and Feeder-free Dual SMAD inhibited-expanded human nasal epithelial cells', Journal of Cystic Fibrosis, 20, pp. 364 - 371, http://dx.doi.org/10.1016/j.jcf.2020.12.019
,2021, 'Avatar acceptability: Views from the australian cystic fibrosis community on the use of personalised organoid technology to guide treatment decisions', ERJ Open Research, 7, pp. 1 - 10, http://dx.doi.org/10.1183/23120541.00448-2020
,2021, 'Integrative resource for network-based investigation of COVID-19 combinatorial drug repositioning and mechanism of action', Patterns, 2, pp. 100325, http://dx.doi.org/10.1016/j.patter.2021.100325
,2021, 'Mesenchymal Stem Cell exosome delivered Zinc Finger Protein activation of cystic fibrosis transmembrane conductance regulator', Journal of Extracellular Vesicles, 10, pp. e12053, http://dx.doi.org/10.1002/jev2.12053
,2021, 'Ageing impairs the airway epithelium defence response to SARS-CoV-2', , http://dx.doi.org/10.1101/2021.04.05.437453
,2020, 'MicroRNA dynamics during hibernation of the Australian central bearded dragon (Pogona vitticeps)', Scientific Reports, 10, pp. 17854, http://dx.doi.org/10.1038/s41598-020-73706-9
,2020, 'Novel Antioxidant Therapy with the Immediate Precursor to Glutathione, -Glutamylcysteine (GGC), Ameliorates LPS-Induced Cellular Stress in In Vitro 3D-Differentiated Airway Model from Primary Cystic Fibrosis Human Bronchial Cells', Antioxidants, 9, pp. 1 - 19, http://dx.doi.org/10.3390/antiox9121204
,2020, 'Evaluating the Alimentary and Respiratory Tracts in Health and disease (EARTH) research programme: a protocol for prospective, longitudinal, controlled, observational studies in children with chronic disease at an Australian tertiary paediatric hospital', BMJ Open, 10, pp. e033916, http://dx.doi.org/10.1136/bmjopen-2019-033916
,2020, 'Novel antioxidant therapy with the immediate precursor to glutathione, γ-glutamylcysteine (GGC), ameliorates LPS-induced cellular stress in an in vitro cystic fibrosis model', , http://dx.doi.org/10.1101/2020.05.27.119990
,2020, 'Significant functional differences despite morphological and molecular similarity in fully differentiated matched Conditionally Reprogrammed (CRC) and Feeder free dual SMAD inhibited expanded human nasal epithelial cells', , http://dx.doi.org/10.1101/2020.05.29.120006
,2019, 'Early glucose abnormalities are associated with pulmonary inflammation in young children with cystic fibrosis', Journal of Cystic Fibrosis, 18, pp. 869 - 873, http://dx.doi.org/10.1016/j.jcf.2019.03.010
,2019, 'Targeted Activation of Cystic Fibrosis Transmembrane Conductance Regulator', Molecular Therapy, 27, pp. 1737 - 1748, http://dx.doi.org/10.1016/j.ymthe.2019.07.002
,2019, 'Waking the sleeping dragon: gene expression profiling reveals adaptive strategies of the hibernating reptile Pogona vitticeps', BMC Genomics, 20, pp. 460, http://dx.doi.org/10.1186/s12864-019-5750-x
,2019, 'Nonlinear sequence similarity between the Xist and Rsx long noncoding RNAs suggests shared functions of tandem repeat domains', RNA, 25, pp. 1004 - 1019, http://dx.doi.org/10.1261/rna.069815.118
,2019, 'Tu1872 – The Human Intestinal Proteome in Children with Cystic Fibrosis', Gastroenterology, 156, pp. S - 1153, http://dx.doi.org/10.1016/s0016-5085(19)39855-5
,2018, 'Human Primary Epithelial Cell Models: Promising Tools in the Era of Cystic Fibrosis Personalized Medicine', Frontiers in Pharmacology, 9, pp. 1429, http://dx.doi.org/10.3389/fphar.2018.01429
,2018, 'Adaptation and conservation insights from the koala genome', Nature Genetics, 50, pp. 1102 - 1111, http://dx.doi.org/10.1038/s41588-018-0153-5
,2018, 'The methylome of vertebrate sex chromosomes', Genes, 9, pp. 230, http://dx.doi.org/10.3390/genes9050230
,2018, 'Landscape of DNA methylation on the marsupial x', Molecular Biology and Evolution, 35, pp. 431 - 439, http://dx.doi.org/10.1093/molbev/msx297
,2017, 'Small RNA interactome of pathogenic E. coli revealed through crosslinking of RNase E', EMBO Journal, 36, pp. 374 - 387, http://dx.doi.org/10.15252/embj.201694639
,2016, 'Source of CpG depletion in the HIV-1 genome', Molecular Biology and Evolution, 33, pp. 3205 - 3212, http://dx.doi.org/10.1093/molbev/msw205
,2015, 'Imprinted X chromosome inactivation: evolution of mechanisms in distantly related mammals', AIMS GENETICS, 2, pp. 110 - 126, http://dx.doi.org/10.3934/genet.2015.2.110
,2014, 'Paternal X inactivation does not correlate with X chromosome evolutionary strata in marsupials', BMC Evolutionary Biology, 14, pp. 267, http://dx.doi.org/10.1186/s12862-014-0267-z
,2013, 'Independent Evolution of Transcriptional Inactivation on Sex Chromosomes in Birds and Mammals', PLoS Genetics, 9, pp. e1003635, http://dx.doi.org/10.1371/journal.pgen.1003635
,2011, 'The cdkn2a g500 allele is more frequent in gbm patients with no defined telomere maintenance mechanism tumors and is associated with poorer survival', PLoS ONE, 6, pp. e26737, http://dx.doi.org/10.1371/journal.pone.0026737
,2011, 'Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development', Genome Biology, 12, pp. 414, http://dx.doi.org/10.1186/gb-2011-12-8-r81
,2011, 'A cross-species comparison of escape from X inactivation in Eutheria: implications for evolution of X chromosome inactivation.', Chromosoma, 121, pp. 71 - 78, http://dx.doi.org/10.1007/s00412-011-0343-8
,