Select Publications
Journal articles
, 2025, 'PA2G4 Functions as a Cofactor for MYC Family Oncoproteins in MYC-Driven Malignancies', Cells, 14, http://dx.doi.org/10.3390/cells14181422
, 2024, 'Combined inhibition of histone methyltransferases EZH2 and DOT1L is an effective therapy for neuroblastoma', Cancer Medicine, 13, pp. e70082, http://dx.doi.org/10.1002/cam4.70082
, 2024, 'Abstract 1080: Using genome-wide CRISPR screening to develop novel combination therapies for high-risk Ewing’s sarcoma', Cancer Research, 84, pp. 1080 - 1080, http://dx.doi.org/10.1158/1538-7445.am2024-1080
, 2023, 'Inhibitors of the Oncogenic PA2G4-MYCN Protein-Protein Interface', Cancers, 15, http://dx.doi.org/10.3390/cancers15061822
, 2020, 'The anti-tumor agent, Dp44mT, promotes nuclear translocation of TFEB via inhibition of the AMPK-mTORC1 axis', Biochimica Et Biophysica Acta Molecular Basis of Disease, 1866, http://dx.doi.org/10.1016/j.bbadis.2020.165970
, 2020, 'Regulation of autophagy and apoptosis by Dp44mT-mediated activation of AMPK in pancreatic cancer cells', Biochimica Et Biophysica Acta Molecular Basis of Disease, 1866, http://dx.doi.org/10.1016/j.bbadis.2019.165657
, 2016, 'The Anticancer Agent, Di-2-Pyridylketone 4,4-Dimethyl-3-Thiosemicarbazone (Dp44mT), Up-Regulates the AMPK-Dependent Energy Homeostasis Pathway in Cancer Cells', Biochimica Et Biophysica Acta Molecular Cell Research, 1863, pp. 2916 - 2933, http://dx.doi.org/10.1016/j.bbamcr.2016.09.011
, 2016, 'Targeting autophagy in antitumor agent design: Furthering the 'lysosomal love' strategy', Future Medicinal Chemistry, 8, pp. 727 - 729, http://dx.doi.org/10.4155/fmc-2016-0066
, 2015, 'Adenosine monophosphate -activated kinase and its key role in catabolism: Structure, regulation, biological activity, and pharmacological activation', Molecular Pharmacology, 87, pp. 363 - 377, http://dx.doi.org/10.1124/mol.114.095810
, 2015, 'The use of iron chelators in biocidal compositions: Evaluation of patent, WO2014059417A1', Expert Opinion on Therapeutic Patents, 25, pp. 367 - 372, http://dx.doi.org/10.1517/13543776.2014.989215
, 2015, 'Iron metabolism and autophagy: A poorly explored relationship that has important consequences for health and disease', Nagoya Journal of Medical Science, 77, pp. 1 - 6
, 2014, 'AMP kinase (PRKAA1)', Journal of Clinical Pathology, 67, pp. 758 - 763, http://dx.doi.org/10.1136/jclinpath-2014-202422
, 2014, 'Gene of the month: BECN1', Journal of Clinical Pathology, 67, pp. 656 - 660, http://dx.doi.org/10.1136/jclinpath-2014-202356
, 2014, 'NDRG1 as a molecular target to inhibit the epithelial-mesenchymal transition: The case for developing inhibitors of metastasis', Future Medicinal Chemistry, 6, pp. 1241 - 1244, http://dx.doi.org/10.4155/fmc.14.80
Conference Papers
, 2018, 'The anticancer agent Dp44mT upregulates the AMPK-dependent energy homeostasis pathway in cancer cells', in MOLECULAR CANCER THERAPEUTICS, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1535-7163.TARG-17-B142