By Dr Tianruo Guo

Journal articles

Fu W; Xue R; Shivdasani MN; Wu Y; Chen D; Guo T; Lovell NH; Goldys EM; Xiang T; Huang Y; Deng F, 2025, 'Advances in biosensors for diagnosis and monitoring of inflammatory bowel disease: A review', Bioengineering and Translational Medicine, 10, pp. e70064, http://dx.doi.org/10.1002/btm2.70064

Italiano ML; Guo T; Tsai D; Lovell NH; Shivdasani MN, 2025, 'The Effects and Interactions of Epiretinal Electrical Stimulation Parameters on Direct and Network-Mediated Activation of Retinal Ganglion Cells', IEEE Transactions on Neural Systems and Rehabilitation Engineering, 33, pp. 4454 - 4467, http://dx.doi.org/10.1109/TNSRE.2025.3627290

Pruscino P; Phan PT; Davies J; Sharma B; Guo T; Nguyen CC; Lovell NH; Do TN, 2025, 'A Proof‐of‐Concept Assessment of a Novel Wearable Eyelid Muscle Device: A Pre‐Clinical Animal Cadaver Study for Eyelid Closure Restoration', Advanced Robotics Research, http://dx.doi.org/10.1002/adrr.202500048

Huang Y; Duan W; Deng F; Tang W; Payne SC; Guo T; Goldys EM; Lovell NH; Shivdasani MN, 2025, 'Towards an Implantable Aptamer Biosensor for Monitoring in Inflammatory Bowel Disease', Biosensors, 15, pp. 546, http://dx.doi.org/10.3390/bios15080546

Chen Q; Liu S; Qin P; Xue J; Deng P; Li Z; Whitelock J; Guo T; Liang K, 2025, 'Improving extracellular matrix penetration with biocatalytic metal-organic framework nanoswimmers', Journal of Materials Chemistry B, 13, pp. 8897 - 8907, http://dx.doi.org/10.1039/d5tb00509d

Chen Y; Qin P; Han J; Zhu G; Bai S; Wen J; Italiano M; Lovell NH; Tsai D; Wang H; Guo T, 2025, 'A computational model of neural signalling under the superposition effect of aligned nodes of Ranvier', Annual International Conference of the IEEE Engineering in Medicine and Biology Society IEEE Engineering in Medicine and Biology Society Annual International Conference, 2025, pp. 1 - 4, http://dx.doi.org/10.1109/EMBC58623.2025.11252983

Zhu G; Deng F; Cai P; Lee KG; Sivasamy A; Wang R; Italiano ML; Li L; Li H; Liu JK; Tsai D; Shivdasani MN; Lovell NH; Ly K; Guo T, 2025, 'Computational framework and tools for evaluating engineered channelrhodopsin performance in a degenerated retina', Annual International Conference of the IEEE Engineering in Medicine and Biology Society IEEE Engineering in Medicine and Biology Society Annual International Conference, 2025, pp. 1 - 4, http://dx.doi.org/10.1109/EMBC58623.2025.11254135

Han J; Qin P; Zhu G; Wang R; Bai S; Wen J; Italiano M; Aplin F; Lovell NH; Tsai D; Wang H; Guo T, 2025, 'Modeling the interplay between myelin architecture and local electromagnetic fields', Annual International Conference of the IEEE Engineering in Medicine and Biology Society IEEE Engineering in Medicine and Biology Society Annual International Conference, 2025, pp. 1 - 4, http://dx.doi.org/10.1109/EMBC58623.2025.11253436

Zhu G; Cai P; Deng F; Sivasamy A; Lee KG; Wang R; Italiano ML; Li L; Li H; Liu JK; Tsai D; Lovell NH; Shivdasani MN; Ly K; Guo T, 2025, 'Optogenetic stimulation of inner retinal neurons restores retinal computations in a virtual degenerated human retina', Annual International Conference of the IEEE Engineering in Medicine and Biology Society IEEE Engineering in Medicine and Biology Society Annual International Conference, 2025, pp. 1 - 4, http://dx.doi.org/10.1109/EMBC58623.2025.11252708

Chia S; Guo T; Goldys EM; Payne SC; Duan W; Lovell NH; Shivdasani MN; Deng F, 2025, 'A CRISPR mediated point-of-care assay for the detection of mucosal calprotectin in an animal model of ulcerative colitis', Bioengineering and Translational Medicine, 10, pp. e10725, http://dx.doi.org/10.1002/btm2.10725

Song X; Guo T; Ma S; Zhou F; Tian J; Liu Z; Liu J; Li H; Chen Y; Chai X; Li L, 2025, 'Spatially Selective Retinal Ganglion Cell Activation Using Low Invasive Extraocular Temporal Interference Stimulation', International Journal of Neural Systems, 35, pp. 2450066, http://dx.doi.org/10.1142/S0129065724500667

Ly K; Italiano ML; Shivdasani MN; Tsai D; Zhang JY; Jiang C; Lovell NH; Dokos S; Guo T, 2025, 'Virtual human retina: Simulating neural signalling, degeneration, and responses to electrical stimulation', Brain Stimulation, 18, pp. 144 - 163, http://dx.doi.org/10.1016/j.brs.2025.01.013

Yu Z; Chen Y; Li J; Chen C; Lu H; Chen S; Zhang T; Guo T; Zhu Y; Jin J; Yan S; Chen H, 2024, 'A tempo-spatial controllable microfluidic shear-stress generator for in-vitro mimicking of the thrombus', Journal of Nanobiotechnology, 22, pp. 187, http://dx.doi.org/10.1186/s12951-024-02334-6

Liang J; Li H; Chai X; Gao Q; Zhou M; Guo T; Chen Y; Di L, 2024, 'An audiovisual cognitive optimization strategy guided by salient object ranking for intelligent visual prothesis systems', Journal of Neural Engineering, 21, pp. 066021 - 066021, http://dx.doi.org/10.1088/1741-2552/ad94a4

Xue R; Deng F; Guo T; Epps A; Lovell NH; Shivdasani MN, 2024, 'Needle-Shaped Biosensors for Precision Diagnoses: From Benchtop Development to In Vitro and In Vivo Applications', Biosensors, 14, pp. 391, http://dx.doi.org/10.3390/bios14080391

Wang X; Zhang Y; Guo T; Wu S; Zhong J; Cheng C; Sui X, 2024, 'Selective intrafascicular stimulation of myelinated and unmyelinated nerve fibers through a longitudinal electrode: A computational study', Computers in Biology and Medicine, 176, pp. 108556 - 108556, http://dx.doi.org/10.1016/j.compbiomed.2024.108556

Muralidharan M; Guo T; Tsai D; Lee JI; Fried S; Dokos S; Morley JW; Lovell NH; Shivdasani MN, 2024, 'Neural activity of retinal ganglion cells under continuous, dynamically-modulated high frequency electrical stimulation', Journal of Neural Engineering, 21, pp. 015001, http://dx.doi.org/10.1088/1741-2552/ad2404

Xu Z; Chen Z; Yang S; Chen S; Guo T; Chen H, 2024, 'Passive Focusing of Single Cells Using Microwell Arrays for High-Accuracy Image-Activated Sorting', Analytical Chemistry, 96, pp. 347 - 354, http://dx.doi.org/10.1021/acs.analchem.3c04195

Zhou M; Su X; Guo T; Meng T; Wu W; Di L; Li L; Li H; Chai X, 2024, 'Optic nerve-mediated modulation of temporally interfering electric fields for potential targeted retinal disease therapy: a computational modeling study', Frontiers in Neuroscience, 18, pp. 1518488, http://dx.doi.org/10.3389/fnins.2024.1518488

Xie Y; Qin P; Guo T; Al Abed A; Lovell NH; Tsai D, 2023, 'Modulating individual axons and axonal populations in the peripheral nerve using transverse intrafascicular multichannel electrodes', Journal of Neural Engineering, 20, http://dx.doi.org/10.1088/1741-2552/aced20

Guo T; Chang YC; Li L; Dokos S; Li L, 2023, 'Editorial: Advances in bioelectronics and stimulation strategies for next generation neuroprosthetics', Frontiers in Neuroscience, 16, http://dx.doi.org/10.3389/fnins.2022.1116900

Yu S; Yue W; Guo T; Liu Y; Zhang Y; Khademi S; Zhou T; Xu Z; Song B; Wu T; Liu F; Tai Y; Yu X; Wang H, 2023, 'The effect of the subthreshold oscillation induced by the neurons' resonance upon the electrical stimulation-dependent instability', Frontiers in Neuroscience, 17, http://dx.doi.org/10.3389/fnins.2023.1178606

Ly K; Guo T; Tsai D; Muralidharan M; Shivdasani MN; Lovell NH; Dokos S, 2022, 'Simulating the impact of photoreceptor loss and inner retinal network changes on electrical activity of the retina', Journal of Neural Engineering, 19, http://dx.doi.org/10.1088/1741-2552/aca221

Chang YC; Ahmed U; Jayaprakash N; Mughrabi I; Lin Q; Wu YC; Gerber M; Abbas A; Daytz A; Gabalski AH; Ashville J; Dokos S; Rieth L; Datta-Chaudhuri T; Tracey KJ; Guo T; Al-Abed Y; Zanos S, 2022, 'kHz-frequency electrical stimulation selectively activates small, unmyelinated vagus afferents', Brain Stimulation, 15, pp. 1389 - 1404, http://dx.doi.org/10.1016/j.brs.2022.09.015

Liu Y; Yue W; Yu S; Zhou T; Zhang Y; Zhu R; Song B; Guo T; Liu F; Huang Y; Wu T; Wang H, 2022, 'A physical perspective to understand myelin II: The physical origin of myelin development', Frontiers in Neuroscience, 16, http://dx.doi.org/10.3389/fnins.2022.951998

Lu Z; Zhou M; Guo T; Liang J; Wu W; Gao Q; Li L; Li H; Chai X, 2022, 'An in-silico analysis of retinal electric field distribution induced by different electrode design of trans-corneal electrical stimulation', Journal of Neural Engineering, 19, http://dx.doi.org/10.1088/1741-2552/ac8e32

Chen C; Li P; Guo T; Chen S; Xu D; Chen H, 2022, 'Generation of Dynamic Concentration Profile Using A Microfluidic Device Integrating Pneumatic Microvalves', Biosensors, 12, http://dx.doi.org/10.3390/bios12100868

Liu Y; Yue W; Yu S; Zhou T; Zhang Y; Zhu R; Song B; Guo T; Liu F; Huang Y; Wu T; Wang H, 2022, 'A physical perspective to understand myelin. I. A physical answer to Peter’s quadrant mystery', Frontiers in Neuroscience, 16, http://dx.doi.org/10.3389/fnins.2022.951942

Chen C; Meng H; Guo T; Deshpande S; Chen H, 2022, 'Development of Paper Microfluidics with 3D-Printed PDMS Barriers for Flow Control', ACS Applied Materials and Interfaces, 14, pp. 40286 - 40296, http://dx.doi.org/10.1021/acsami.2c08541

Italiano ML; Guo T; Lovell NH; Tsai D, 2022, 'Improving the spatial resolution of artificial vision using midget retinal ganglion cell populations modeled at the human fovea', Journal of Neural Engineering, 19, http://dx.doi.org/10.1088/1741-2552/ac72c2

Song X; Qiu S; Shivdasani MN; Zhou F; Liu Z; Ma S; Chai X; Chen Y; Cai X; Guo T; Li L, 2022, 'An in-silico analysis of electrically evoked responses of midget and parasol retinal ganglion cells in different retinal regions', Journal of Neural Engineering, 19, http://dx.doi.org/10.1088/1741-2552/ac5b18

Ge Y; Ye S; Zhu K; Guo T; Su D; Zhang D; Chen Y; Chai X; Sui X, 2020, 'Mediating different-diameter Aβ nerve fibers using a biomimetic 3D TENS computational model', Journal of Neuroscience Methods, 346, http://dx.doi.org/10.1016/j.jneumeth.2020.108891

Song X; Guo T; Shivdasani MN; Dokos S; Lovell NH; Li X; Qiu S; Li T; Zheng S; Li L, 2020, 'Creation of virtual channels in the retina using synchronous and asynchronous stimulation - A modelling study', Journal of Neural Engineering, 17, http://dx.doi.org/10.1088/1741-2552/abc3a9

Barriga-Rivera A; Guo T; Hayashida Y; Suaning GJ, 2020, 'Editorial: A Conversation With the Brain: Can We Speak Its Language?', Frontiers in Neuroscience, 14, http://dx.doi.org/10.3389/fnins.2020.00794

Muralidharan M; Guo T; Shivdasani MN; Tsai D; Fried S; Li L; Dokos S; Morley JW; Lovell NH, 2020, 'Neural activity of functionally different retinal ganglion cells can be robustly modulated by high-rate electrical pulse trains', Journal of Neural Engineering, 17, http://dx.doi.org/10.1088/1741-2552/ab9a97

Rathbun DL; Shivdasani MN; Guo T; Fried S; Lovell NH; Hessburg P, 2020, 'The eye and the chip 2019 - Conference Report', Journal of Neural Engineering, 17, pp. 010401, http://dx.doi.org/10.1088/1741-2552/ab60c0

Office FP; Al Abed A; Guo T; Tsai D, 2019, 'Erratum: Mediating Retinal Ganglion Cell Spike Rates Using High-Frequency Electrical Stimulation', Frontiers in Neuroscience, 13, pp. 910, http://dx.doi.org/10.3389/fnins.2019.00910

Bai S; Martin D; Guo T; Dokos S; Loo C, 2019, 'Computational comparison of conventional and novel electroconvulsive therapy electrode placements for the treatment of depression', European Psychiatry, 60, pp. 71 - 78, http://dx.doi.org/10.1016/j.eurpsy.2019.05.006

Guo T; Tsai D; Yang CY; Al Abed A; Twyford P; Fried SI; Morley JW; Suaning GJ; Dokos S; Lovell NH, 2019, 'Mediating retinal ganglion cell spike rates using high-frequency electrical stimulation', Frontiers in Neuroscience, 13, pp. 413, http://dx.doi.org/10.3389/fnins.2019.00413

Yang CY; Tsai D; Guo T; Dokos S; Suaning G; Morley JM; Lovell N; Morley J, 2018, 'Differential Electrical Responses in Retinal Ganglion Cell Subtypes: Effects of Synaptic Blockade and Stimulating Electrode Location', Journal of Neural Engineering, 15, pp. 046020, http://dx.doi.org/10.1088/1741-2552/aac315

Guo T; Yang CY; Tsai D; Muralidharan M; Suaning G; Morley J; Dokos S; Lovell N, 2018, 'Closed-Loop Efficient Searching of Optimal Electrical Stimulation Parameters for Preferential Excitation of Retinal Ganglion Cells', Frontiers in Neuroscience, 12, pp. 168, http://dx.doi.org/10.3389/fnins.2018.00168

Barriga-Rivera A; Guo T; Yang CY; Abed AA; Dokos S; Lovell NH; Morley JW; Suaning GJ; Al Abed A, 2017, 'High-amplitude electrical stimulation can reduce elicited neuronal activity in visual prosthesis', Scientific Reports, 7, pp. 42682, http://dx.doi.org/10.1038/srep42682

Xie HB; Zhou P; Guo T; Sivakumar B; Zhang X; Dokos S, 2016, 'Multiscale Two-Directional Two-Dimensional Principal Component Analysis and Its Application to High-Dimensional Biomedical Signal Classification', IEEE Transactions on Biomedical Engineering, 63, pp. 1416 - 1425, http://dx.doi.org/10.1109/TBME.2015.2436375

Guo T; Tsai D; Morley JW; Suaning GJ; Kameneva T; Lovell NH; Dokos S, 2016, 'Electrical activity of on and off retinal ganglion cells: A modelling study', Journal of Neural Engineering, 13, http://dx.doi.org/10.1088/1741-2560/13/2/025005

Xie HB; Guo T; Sivakumar B; Liew AWC; Dokos S, 2014, 'Symplectic geometry spectrum analysis of nonlinear time series', Proceedings of the Royal Society A Mathematical Physical and Engineering Sciences, 470, http://dx.doi.org/10.1098/rspa.2014.0409

Xie HB; Guo T; Bai S; Dokos S, 2014, 'Hybrid soft computing systems for electromyographic signals analysis: A review', Biomedical Engineering Online, 13, pp. 8, http://dx.doi.org/10.1186/1475-925X-13-8

Guo T; Tsai D; Bai S; Morley JW; Suaning GJ; Lovell NH; Dokos S, 2014, 'Understanding the retina: A review of computational models of the retina from the single cell to the network level', Critical Reviews in Biomedical Engineering, 42, pp. 419 - 436, http://dx.doi.org/10.1615/CritRevBiomedEng.2014011732

Guo T; Al Abed A; Lovell NH; Dokos S, 2013, 'Erratum: Optimisation of a generic ionic model of cardiac myocyte electrical activity (Computational and Mathematical Methods in Medicine)', Computational and Mathematical Methods in Medicine, 2013, http://dx.doi.org/10.1155/2013/213563

Al Abed A; Guo T; Lovell NH; Dokos S, 2013, 'Optimisation of ionic models to fit tissue action potentials: Application to 3D atrial modelling', Computational and Mathematical Methods in Medicine, 2013, pp. 951234, http://dx.doi.org/10.1155/2013/951234

Guo T; Al abed A; Lovell NH; Dokos S, 2013, 'Optimisation of a generic ionic model of cardiac myocyte electrical activity', Computational and Mathematical Methods in Medicine, 2013, pp. Article number706195, http://dx.doi.org/10.1155/2013/706195

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