By Emeritus Scientia Professor Eugenie Ruth Lumbers

Book Chapters

Lumbers ER, 2025, 'The Physiological Roles of the Renin Angiotensin Aldosterone System and Vasopressin in Human Pregnancy', in Maternal Fetal and Neonatal Endocrinology Physiology Pathophysiology and Clinical Management, pp. 139 - 155, http://dx.doi.org/10.1016/B978-0-443-23940-3.00001-6

Pringle KG; Lumbers ER; Morosin SK; Delforce SJ, 2023, 'The role of angiotensins in the pathophysiology of human pregnancy', in Angiotensin from the Kidney to Coronavirus, pp. 179 - 211, http://dx.doi.org/10.1016/B978-0-323-99618-1.00029-5

Lumbers ER, 2020, 'The Physiological Roles of the Renin-Angiotensin Aldosterone System and Vasopressin in Human Pregnancy', in Maternal Fetal and Neonatal Endocrinology Physiology Pathophysiology and Clinical Management, pp. 129 - 145, http://dx.doi.org/10.1016/B978-0-12-814823-5.00010-6

Lumbers ER, 2020, 'Chapter 10 The Physiological Roles of the Renin-Angiotensin Aldosterone System and Vasopressin in Human Pregnancy', in Maternal-Fetal and Neonatal Endocrinology, Elsevier, pp. 129 - 145, http://dx.doi.org/10.1016/b978-0-12-814823-5.00010-6

Lumbers ER, 2019, 'The Physiological Roles of the Renin-Angiotensin Aldosterone System and Vasopressin in Human Pregnancy', in Maternal Fetal and Neonatal Endocrinology Physiology Pathophysiology and Clinical Management, pp. 129 - 145, http://dx.doi.org/10.1016/B978-0-12-814823-5.00010-6

Pringle KG; Lumbers ER, 2013, 'The placental renin angiotensin system', in Placenta Development Function and Diseases, pp. 261 - 288

Lumbers ER, 2000, 'Fetal renal circulation', in Advances in Organ Biology, JAI Press Inc, Greenwich, Connecticut, USA, pp. 275 - 299

Lumbers ER, 2000, 'The renal circulation in pregnancy', in Advances in Organ Biology, JAI Press Inc, Greenwich, Connecticut, USA, pp. 301 - 316

Lumbers ER, 1999, 'Angiotensin II effects on reproductive biology: Physiology or Pharmacological curiosity?', in Drugs, Enzymes and Receptors of the Renin-Angiotensin System: Celebrating a Century of Discovery, Harwood Academic Publishers, Amsterdam, The Netherlands, pp. 67 - 88

Lumbers ER; Gibson KJ; Stevenson KM, 1998, 'Changes in renal function at birth', in Body Fluids and Kidney Function, Cambridge University Press, Cambridge, UK, pp. 106 - 143

Stevens AD; Lumbers ER, 1981, 'FACTORS INFLUENCING RENAL SODIUM EXCRETION IN THE FETAL LAMB', in Kidney and Body Fluids, Elsevier, pp. 119 - 123, http://dx.doi.org/10.1016/b978-0-08-026824-8.50015-1

Lumbers ER; Potter EK; McCloskey DI; Ismay MJ; Lee WB; Stevens AD, 1981, 'The Effects of Intravenous Angiotensin II on the Cardiac Baroreceptor Reflex', in Frontiers in Hypertension Research, Springer New York, pp. 556 - 558, http://dx.doi.org/10.1007/978-1-4612-5899-5_91

Journal articles

Arthurs AL; Lumbers ER; Schofield L; Lees C; Chin PY; Care AS; Robertson SA; Schjenken JE; Pringle KG, 2026, 'miR-155 suppresses angiotensin II type 1 receptor synthesis during placental morphogenesis', Cell Death Discovery, 12, http://dx.doi.org/10.1038/s41420-025-02892-0

Symington TL; Fisher JJ; Zhou W; Dimitriadis E; Lumbers ER; Tooney P; Pringle KG, 2026, 'Characterization of elevated levels of endometrial renin–angiotensin system components suggest a role in endometrial repair', Frontiers in Endocrinology, 17, pp. 1817846, http://dx.doi.org/10.3389/fendo.2026.1817846

Brooker IA; Sutherland JM; Endacott SK; Lumbers ER; Fisher JJ; Pringle KG, 2025, 'Angiotensin-converting enzyme 2 regulates the placental response to repeated hypoxia–reoxygenation insult', Journal of Physiology, 603, pp. 7305 - 7321, http://dx.doi.org/10.1113/JP289678

Delforce SJ; Mohammed R; Symington TL; Wang Y; Verrills NM; Lumbers ER; Pringle KG, 2025, 'Effects of Inhibitors of the Activity of the Circulating Renin–Angiotensin System on the Growth and Proliferation of Endometrial Cancer Cells', International Journal of Molecular Sciences, 26, http://dx.doi.org/10.3390/ijms262210968

Schofield LG; Zhao J; Wang Y; Delforce SJ; Endacott SK; Lumbers ER; Ma D; Pringle KG, 2025, 'Unravelling soluble (pro)renin receptor-mediated endothelial dysfunction', European Journal of Pharmacology, 996, http://dx.doi.org/10.1016/j.ejphar.2025.177601

Brooker IA; Fisher JJ; Delforce SJ; Endacott SK; Lumbers ER; Sutherland JM; Pringle KG, 2025, 'Characterising the role of placental angiotensin-converting enzyme 2 (ACE2) during the onset of oxidative insult by hypoxia/reoxygenation: Implications for fetal growth restriction', Placenta, 165, pp. 82 - 90, http://dx.doi.org/10.1016/j.placenta.2025.04.008

Brooker I; Sutherland J; Endacott S; Lumbers E; Fisher J; Pringle K, 2025, 'Decreased placental ACE2 activity is associated with disrupted redox homeostasis in fetal growth restriction', Placenta, 171, pp. e297 - e298, http://dx.doi.org/10.1016/j.placenta.2025.08.209

Schofield LG; Endacott SK; Delforce SJ; Lumbers ER; Pringle KG, 2024, 'Importance of the (Pro)renin Receptor in Activating the Renin-Angiotensin System During Normotensive and Preeclamptic Pregnancies', Current Hypertension Reports, 26, pp. 483 - 495, http://dx.doi.org/10.1007/s11906-024-01316-1

Endacott SK; Brennan C; Kahl RGS; Onifade OM; Rae KM; Lumbers ER; Pringle KG, 2024, 'Soluble (pro)renin receptor (s(P)RR) levels in women carrying Aboriginal and/or Torres Strait Islander babies; the Gomeroi Gaaynggal study', Pregnancy Hypertension, 38, http://dx.doi.org/10.1016/j.preghy.2024.101169

Schofield LG; Delforce SJ; Pryor JC; Endacott SK; Lumbers ER; Marshall SA; Pringle KG, 2024, 'The soluble (pro)renin receptor promotes a preeclampsia-like phenotype both in vitro and in vivo', Hypertension Research, 47, pp. 1627 - 1641, http://dx.doi.org/10.1038/s41440-024-01678-8

Lozinski M; Lumbers ER; Bowden NA; Martin JH; Fay MF; Pringle KG; Tooney PA, 2024, 'Upregulation of the Renin–Angiotensin System Is Associated with Patient Survival and the Tumour Microenvironment in Glioblastoma', Cells, 13, http://dx.doi.org/10.3390/cells13070634

Brooker I; Fisher J; Sutherland J; Lumbers E; Pringle K, 2024, 'Unravelling the Protective Role of Placental ACE2 During Chronic Hypoxia/Reoxygenation', Placenta, 154, pp. e25 - e25, http://dx.doi.org/10.1016/j.placenta.2024.07.127

Schofield LG; Kahl RGS; Rodrigues SL; Fisher JJ; Endacott SK; Delforce SJ; Lumbers ER; Martin JH; Pringle KG, 2023, 'Placental deficiency of the (pro)renin receptor ((P)RR) reduces placental development and functional capacity', Frontiers in Cell and Developmental Biology, 11, http://dx.doi.org/10.3389/fcell.2023.1212898

Schofield L; Delforce S; Morosin S; Lumbers E; Kirsty P, 2023, 'Elevated soluble prorenin receptor impairs endothelial function in-vitro, promoting a preeclamptic phenotype.', Placenta, 140, pp. e73 - e73, http://dx.doi.org/10.1016/j.placenta.2023.07.232

Barin B; Kozlakidis Z; Ricci F; Su L; Tsioutis C; Welburn SC; Ropert C; Iosa M; Rawson T; Sun J; Lumbers ER, 2022, 'Editorial: Coronavirus Disease (COVID-19): Pathophysiology, Epidemiology, Clinical Management and Public Health Response, Volume II', Frontiers in Public Health, 10, pp. 913507 - 913507, http://dx.doi.org/10.3389/fpubh.2022.913507

Tamanna S; Morosin SK; Delforce SJ; van Helden DF; Lumbers ER; Pringle KG, 2022, 'Renin-angiotensin system (RAS) enzymes and placental trophoblast syncytialisation', Molecular and Cellular Endocrinology, 547, http://dx.doi.org/10.1016/j.mce.2022.111609

Jarrott B; Head R; Pringle KG; Lumbers ER; Martin JH, 2022, '“LONG COVID”—A hypothesis for understanding the biological basis and pharmacological treatment strategy', Pharmacology Research and Perspectives, 10, http://dx.doi.org/10.1002/prp2.911

Head RJ; Lumbers ER; Jarrott B; Tretter F; Smith G; Pringle KG; Islam S; Martin JH, 2022, 'Systems analysis shows that thermodynamic physiological and pharmacological fundamentals drive COVID-19 and response to treatment', Pharmacology Research and Perspectives, 10, http://dx.doi.org/10.1002/prp2.922

Lumbers ER; Head R; Smith GR; Delforce SJ; Jarrott B; H. Martin J; Pringle KG, 2022, 'The interacting physiology of COVID-19 and the renin-angiotensin-aldosterone system: Key agents for treatment', Pharmacology Research and Perspectives, 10, http://dx.doi.org/10.1002/prp2.917

Morris BJ; Katelaris A; Blumenthal NJ; Hajoona M; Sheen AC; Schrieber L; Lumbers ER; Wodak AD; Katelaris P, 2022, 'Evidence-based circumcision policy for Australia', Journal of Men S Health, 18, http://dx.doi.org/10.31083/j.jomh1806132

Martin JH; Mohammed R; Delforce SJ; Skerrett-Byrne DA; de Meaultsart CC; Almazi JG; Stephens AN; Verrills NM; Dimitriadis E; Wang Y; Lumbers ER; Pringle KG, 2022, 'Role of the prorenin receptor in endometrial cancer cell growth', Oncotarget, 13, pp. 587 - 599, http://dx.doi.org/10.18632/ONCOTARGET.28224

Tamanna S; Lumbers ER; Morosin SK; Delforce SJ; Pringle KG, 2021, 'ACE2: A key modulator of the renin-angiotensin system and pregnancy', American Journal of Physiology Regulatory Integrative and Comparative Physiology, 321, pp. R833 - R843, http://dx.doi.org/10.1152/ajpregu.00211.2021

Morosin SK; Lochrin AJ; Delforce SJ; Lumbers ER; Pringle KG, 2021, 'The (pro)renin receptor ((P)RR) and soluble (pro)renin receptor (s(P)RR) in pregnancy', Placenta, 116, pp. 43 - 50, http://dx.doi.org/10.1016/j.placenta.2021.04.015

Morosin SK; Delforce SJ; Kahl RGS; de Meaultsart CC; Lumbers ER; Pringle KG, 2021, 'The (pro)renin receptor and soluble (pro)renin receptor in choriocarcinoma', Reproduction, 162, pp. 375 - 384, http://dx.doi.org/10.1530/REP-20-0650

Morosin SK; Delforce SJ; Corbisier de Meaultsart C; Lumbers ER; Pringle KG, 2021, 'FURIN and placental syncytialisation: a cautionary tale', Cell Death and Disease, 12, http://dx.doi.org/10.1038/s41419-021-03898-z

Tamanna S; Clifton VL; Rae K; van Helden DF; Lumbers ER; Pringle KG, 2021, 'Corrigendum: Angiotensin Converting Enzyme 2 (ACE2) in Pregnancy: Preeclampsia and Small for Gestational Age (Frontiers in Physiology, (2020), 11, (590787), 10.3389/fphys.2020.590787)', Frontiers in Physiology, 12, http://dx.doi.org/10.3389/fphys.2021.692761

Lee YQ; Lumbers ER; Schumacher TL; Collins CE; Rae KM; Pringle KG, 2021, 'Maternal diet influences fetal growth but not fetal kidney volume in an australian indigenous pregnancy cohort', Nutrients, 13, pp. 1 - 18, http://dx.doi.org/10.3390/nu13020569

Delforce S; Lumbers E; Burns G; Marsland M; Zakar T; Pringle K, 2021, 'The anti-inflammatory role of Angiotensin-(1-7) in human intrauterine tissues', Placenta, 112, pp. e70 - e71, http://dx.doi.org/10.1016/j.placenta.2021.07.227

Morosin SK; Delforce SJ; Lumbers ER; Pringle KG, 2020, 'Cleavage of the soluble (pro)renin receptor (sATP6AP2) in the placenta', Placenta, 101, pp. 49 - 56, http://dx.doi.org/10.1016/j.placenta.2020.08.019

Tamanna S; Clifton VL; Rae K; van Helden DF; Lumbers ER; Pringle KG, 2020, 'Angiotensin Converting Enzyme 2 (ACE2) in Pregnancy: Preeclampsia and Small for Gestational Age', Frontiers in Physiology, 11, http://dx.doi.org/10.3389/fphys.2020.590787

Kandasamy Y; Rudd D; Lumbers ER; Smith R, 2020, 'An evaluation of preterm kidney size and function over the first two years of life', Pediatric Nephrology, 35, pp. 1477 - 1482, http://dx.doi.org/10.1007/s00467-020-04554-y

Morosin SK; Delforce SJ; Lumbers ER; Pringle KG, 2020, 'The (pro)renin receptor (ATP6AP2) does not play a role in syncytialisation of term human primary trophoblast cells', Placenta, 97, pp. 89 - 94, http://dx.doi.org/10.1016/j.placenta.2020.05.009

Lumbers ER; Kandasamy Y; Delforce SJ; Boyce AC; Gibson KJ; Pringle KG, 2020, 'Programming of Renal Development and Chronic Disease in Adult Life', Frontiers in Physiology, 11, http://dx.doi.org/10.3389/fphys.2020.00757

Lumbers ER; Delforce SJ; Pringle KG; Smith GR, 2020, 'The Lung, the Heart, the Novel Coronavirus, and the Renin-Angiotensin System; The Need for Clinical Trials', Frontiers in Medicine, 7, http://dx.doi.org/10.3389/fmed.2020.00248

Lumbers ER; Delforce SJ; Arthurs AL; Pringle KG, 2019, 'Causes and Consequences of the Dysregulated Maternal Renin-Angiotensin System in Preeclampsia', Frontiers in Endocrinology, 10, http://dx.doi.org/10.3389/fendo.2019.00563

Lee YQ; Lumbers ER; Oldmeadow C; Collins CE; Johnson V; Keogh L; Sutherland K; Gordon A; Smith R; Rae KM; Pringle KG, 2019, 'The relationship between maternal adiposity during pregnancy and fetal kidney development and kidney function in infants: the Gomeroi gaaynggal study', Physiological Reports, 7, http://dx.doi.org/10.14814/phy2.14227

Morris BJ; Hankins CA; Lumbers ER; Mindel A; Klausner JD; Krieger JN; Cox G, 2019, 'Sex and Male Circumcision: Women's Preferences Across Different Cultures and Countries: A Systematic Review', Sexual Medicine, 7, pp. 145 - 161, http://dx.doi.org/10.1016/j.esxm.2019.03.003

Arthurs AL; Lumbers ER; Pringle KG, 2019, 'MicroRNA mimics that target the placental renin-Angiotensin system inhibit trophoblast proliferation', Molecular Human Reproduction, 25, pp. 218 - 227, http://dx.doi.org/10.1093/molehr/gaz010

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