By Mr Bala Umashankar

Journal articles

Umashankar B; Pazderka C; York E; King A; Rahman MK; Choucair H; Bourget K; Gale PA; Rawling T; Murray M, 2025, 'Mitochondrial targeting and anticancer cell killing by arylurea-fatty acids containing in-chain sulfur atoms', Journal of Pharmaceutical Sciences, 114, http://dx.doi.org/10.1016/j.xphs.2025.103933

Tam S; Umashankar B; Rahman MK; Choucair H; Rawling T; Murray M, 2024, 'The Novel Anticancer Aryl-Ureido Fatty Acid CTU Increases Reactive Oxygen Species Production That Impairs Mitochondrial Fusion Mechanisms and Promotes MDA-MB-231 Cell Death', International Journal of Molecular Sciences, 25, http://dx.doi.org/10.3390/ijms251910577

Umashankar B; Eliasson L; Ooi CY; Kim KW; Shaw JAM; Waters SA, 2024, 'Beyond insulin: Unraveling the complex interplay of ER stress, oxidative damage, and CFTR modulation in CFRD', Journal of Cystic Fibrosis, 23, pp. 842 - 852, http://dx.doi.org/10.1016/j.jcf.2024.06.004

Rahman MK; Umashankar B; Choucair H; Bourget K; Rawling T; Murray M, 2024, 'The inositol-requiring enzyme 1 (IRE1) endoplasmic reticulum stress pathway promotes MDA-MB-231 cell survival and renewal in response to the aryl-ureido fatty acid CTU', International Journal of Biochemistry and Cell Biology, 171, http://dx.doi.org/10.1016/j.biocel.2024.106571

Wong SL; Kardia E; Vijayan A; Umashankar B; Pandzic E; Zhong L; Jaffe A; Waters SA, 2023, 'Molecular and Functional Characteristics of Airway Epithelium under Chronic Hypoxia', International Journal of Molecular Sciences, 24, http://dx.doi.org/10.3390/ijms24076475

Rahman MK; Umashankar B; Choucair H; Pazderka C; Bourget K; Chen Y; Dunstan CR; Rawling T; Murray M, 2023, 'Inclusion of the in-chain sulfur in 3-thiaCTU increases the efficiency of mitochondrial targeting and cell killing by anticancer aryl-urea fatty acids', European Journal of Pharmacology, 939, http://dx.doi.org/10.1016/j.ejphar.2022.175470

Choucair H; Rahman MK; Umashankar B; Al-Zubaidi Y; Bourget K; Chen Y; Dunstan C; Rawling T; Murray M, 2022, 'The aryl-ureido fatty acid CTU activates endoplasmic reticulum stress and PERK/NOXA-mediated apoptosis in tumor cells by a dual mitochondrial-targeting mechanism', Cancer Letters, 526, pp. 131 - 141, http://dx.doi.org/10.1016/j.canlet.2021.11.022

al-Zubaidi Y; Chen Y; Khalilur Rahman M; Umashankar B; Choucair H; Bourget K; Chung L; Qi Y; Witting PK; Anderson RL; O'Neill GM; Dunstan CR; Rawling T; Murray M, 2021, 'PTU, a novel ureido-fatty acid, inhibits MDA-MB-231 cell invasion and dissemination by modulating Wnt5a secretion and cytoskeletal signaling', Biochemical Pharmacology, 192, http://dx.doi.org/10.1016/j.bcp.2021.114726

Al-Zubaidi Y; Pazderka C; Koolaji N; Rahman MK; Choucair H; Umashankar B; Bourget K; Chen Y; Rawling T; Murray M, 2019, 'Aryl-urea fatty acids that activate the p38 MAP kinase and down-regulate multiple cyclins decrease the viability of MDA-MB-231 breast cancer cells', European Journal of Pharmaceutical Sciences, 129, pp. 87 - 98, http://dx.doi.org/10.1016/j.ejps.2018.12.015

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