By Professor Adam Jaffe

Conference Abstracts

Strachan R; Beggs S; Fearon D; Gilbert G; Homaira N; Lambert S; Marshall H; Martin A; McCallum G; McCullagh A; McDonald T; Mcintyre P; Oftadeh S; Ranganathan S; Suresh S; Teoh L; Twaij A; Wainwright C; Wong M; Snelling T; Jaffe A, 2018, 'THE IMPACT OF THE 13 VALENT CONJUGATE PNEUMOCOCCAL VACCINE ON PNEUMOCOCCAL SEROTYPES CAUSING CHILDHOOD EMPYEMA IN AUSTRALIA', in RESPIROLOGY, WILEY, Vol. 23, pp. 166 - 166

Garg M; Leach ST; Needham B; Coffey MJ; Katz TE; Strachan R; Widger J; Field P; Belessis Y; Chuang S; Day AS; Jaffe A; Ooi CY, 2017, 'AGE-RELATED LEVELS OF STOOL M2-PYRUVATE KINASE IN CHILDREN WITH CYSTIC FIBROSIS AND HEALTHY CONTROLS', in PEDIATRIC PULMONOLOGY, WILEY, Vol. 52, pp. S454 - S455, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000411113700697&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Saddi V; Beggs S; Bennetts B; Harrison J; Hime N; Kapur N; Lipsett J; Nogee LM; Phu A; Suresh S; Schultz A; Selvadurai H; Sherrard S; Strachan R; Vyas J; Zurynski Y; Jaffé A, 2017, 'Childhood interstitial lung diseases in immunocompetent children in Australia and New Zealand: A decade's experience', in Orphanet Journal of Rare Diseases, Vol. 12, http://dx.doi.org/10.1186/s13023-017-0637-x

Ooi CY; Garg M; Young K; Needham B; Leach S; Jaffe A; Avolio J; Ratjen F; Tullis E; Gonska T, 2016, 'IMPROVEMENT IN INTESTINAL INFLAMMATION ON IVACAFTOR', in PEDIATRIC PULMONOLOGY, WILEY-BLACKWELL, Vol. 51, pp. 272 - 272, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000384815300289&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Jeyaratnam B; Kennedy B; McBride J; Field P; Robinson PD; Belessis Y; Widger J; Plush L; Coward E; Jaffe A; Selvadurai H, 2016, 'Children with Empyema Have Exercise Limitation at Least Four Years After Admission- a Pilot Study', in American Journal of Respiratory and Critical Care Medicine, Vol. 193, pp. a3041 - a3041, http://dx.doi.org/10.1164/ajrccm-conference.2016.193.1_meetingabstracts.a3041

Hew M; Gillman A; Sutherland M; Wark P; Bowden J; McDonald V; Guo M; Reddel H; Jenkins C; Marks G; Upham J; Thien F; Rimmer J; Katsoulotos GP; Cook M; Yang I; Katelaris C; Bowler S; Langton D; Gibson PG; Robinson PD; Wright C; Bint M; Yozghatlian V; Burgess S; Sivakumaran P; Jaffe A; Yan K; Peters M; Kritikos V; Baraket M; Aminazad A, 2016, 'Clinical Effectiveness of Omalizumab in Severe Allergic Asthma Above the Recommended Dosing Range: the Australian Xolair Registry', in American Journal of Respiratory and Critical Care Medicine, Vol. 193, pp. a1407 - a1407, http://dx.doi.org/10.1164/ajrccm-conference.2016.193.1_meetingabstracts.a1407

Mui J; Numa A; Jaffe A; Chuang S, 2016, 'Nutritional Follow-Up of Congenital Diaphragmatic Hernia Survivors – the Sydney Children's Hospital Experience', in American Journal of Respiratory and Critical Care Medicine, Vol. 193, pp. a6578 - a6578, http://dx.doi.org/10.1164/ajrccm-conference.2016.193.1_meetingabstracts.a6578

Jeyaratnam B; Kennedy B; Mcbride J; Field P; Robinson P; Belessis Y; Widger J; Coward E; Plush L; Jaffe A; Selvadurai H, 2016, 'CHILDREN WITH EMPYEMA HAVE EXERCISE LIMITATION AT LEAST FOUR YEARS AFTER ADMISSION- A PILOT STUDY', in RESPIROLOGY, WILEY-BLACKWELL, Vol. 21, pp. 180 - 180, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000373102400403&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Hew M; Gillman A; Sutherland M; Wark P; Bowden J; Macdonald V; Guo M; Reddel H; Jenkins C; Marks G; Upham J; Thien F; Rimmer J; Katsoulotos G; Cook M; Yang I; Katelaris C; Bowler S; Langton D; Gibson P; Robinson P; Wright C; Bint M; Yozghatlian V; Burgess S; Sivakumaran P; Jaffe A; Yan KY; Kritikos V; Peters M; Baraket M; Aminazad A, 2016, 'CLINICAL EFFECTIVENESS OF OMALIZUMAB IN SEVERE ALLERGIC ASTHMA ABOVE THE STANDARD DOSING RANGE: THE AUSTRALIAN XOLAIR REGISTRY', in RESPIROLOGY, WILEY-BLACKWELL, Vol. 21, pp. 102 - 102, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000373102400206&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Rolfe Z; Bell R; Jaffe A; Belessis Y, 2016, 'CLINICAL OUTCOMES OF EARLY PSEUDOMONAS INFECTION IN INFANTS AND YOUNG CHILDREN WITH CYSTIC FIBROSIS', in RESPIROLOGY, WILEY-BLACKWELL, Vol. 21, pp. 167 - 167, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000373102400372&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Mui J; Numa A; Chuang S; Jaffe A, 2016, 'NUTRITIONAL FOLLOW-UP OF CONGENITAL DIAPHRAGMATIC HERNIA SURVIVORS - THE SYDNEY CHILDREN'S HOSPITAL EXPERIENCE', in RESPIROLOGY, WILEY-BLACKWELL, Vol. 21, pp. 181 - 181, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000373102400406&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Liu N; Stelzer-Braid S; D'Cunha R; Belessis Y; Jaffe A; Doumit M; Tovey E; Rawlinson W, 2015, 'HUMAN RHINOVIRUS INFECTIONS IN THE CLINICAL EXACERBATIONS OF CHILDREN WITH CYSTIC FIBROSIS', in RESPIROLOGY, WILEY-BLACKWELL, AUSTRALIA, Queensland, Vol. 20, pp. 47 - 47, presented at Thoracic Society Australia New Zealand Australian New Zealand Society Respiratory Science Annual Scientific Meeting 2015, AUSTRALIA, Queensland, 27 March 2015 - 01 April 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000351464400124&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Stelzer-Braid S; Tovey E; Willenborg C; Toelle B; Ampon R; Garden F; Oliver B; Strachan R; Belessis Y; Jaffe A; Reddel H; Crisafulli D; Marks G; Rawlinson W, 2015, 'Absence of seasonal peaks in human rhinovirus and asthma exacerbations in a cohort of children with asthma contrasts to community incidence of disease exacerbations', in Respirology, Wiley, Vol. 20, pp. 54 - 54, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000351464400143&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Stelzer-Braid S; Toelle B; Willenborg C; Garden F; Strachan R; Jaffe A; Oliver B; Belessis Y; Reddel H; Marks G; Rawlinson W; Tovey E, 2014, 'SNEEZING LEADS TO WHEEZING: RHINOVIRUS INFECTION IN THE STUDY OF ASTHMA, VIRUSES AND ENVIRONMENT (SAVE) COHORT', in RESPIROLOGY, WILEY-BLACKWELL, Vol. 19, pp. 38 - 38, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000333238100092&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Tovey ER; Stelzer-Braid S; Toelle BG; Willenborg CM; Reddel HK; Garden FL; Jaffe A; Strachan R; Oliver BG; Belessis YC; Marks GB; Rawlinson WD, 2014, 'Asthma Symptoms and Rhinovirus In A Longitudinal Children's Cohort', in The Journal of Allergy and Clinical Immunology, Elsevier, Vol. 133, pp. ab285, http://dx.doi.org/10.1016/j.jaci.2013.12.1010

Working Papers

Capraro A; Wong SL; Adhikari A; Allan KM; Patel HR; Zhong L; Raftery M; Jaffe A; Yeang M; Aggarwal A; Wu L; Pandzic E; Whan RM; Turville S; Vittorio O; Bull RA; Kaakoush N; Rawlinson WD; Tedla N; Vafaee F; Waters SA, Ageing impairs the airway epithelium defence response to SARS-CoV-2, Cold Spring Harbor Laboratory, http://dx.doi.org10.1101/2021.04.05.437453

Media

Waters S; Jaffe A, 2019, Patients’ avatars being used to test cystic fibrosis drugs, https://newsroom.unsw.edu.au/news/health/patients%E2%80%99-avatars-being-used-test-cystic-fibrosis-drugs

Waters S; Jaffe A, 2019, Mini-organ unlock new understanding about drug and disease, https://www.abc.net.au/radionational/programs/healthreport/

Waters S; Jaffe A, 2019, AVATARS: A revolution in cystic fibrosis treatment. INSPIRE Research Australia, https://issuu.com/researchaustralia/docs/inspire_issue_13_final

Waters S; Jaffe A, 2019, Avatars-a-game-changer-for-children-with-cystic-fibrosis, https://www.schn.health.nsw.gov.au/news/articles/2019/07/avatars-a-game-changer-for-children-with-cystic-fibrosis

Waters S; Jaffe A, 2019, New treatment giving hope to kids with cystic fibrosis, https://www.youtube.com/watch?time_continue=1&v=66eXL0fy1JA&feature=emb_logo

Waters S; Prentice B; Jaffe A, 2018, Avatars take lead role in future CF therapy., https://www.ausdoc.com.au/therapy-update/avatars-take-lead-role-future-cf-therapy

Preprints

Homaira N; Strachan R; Quinn H; Beggs S; Bhuiyan M; Bowen A; Fawcett LK; gilbert L; Lambert SB; Macartney K; Marshall HS; Martin AC; McCallum G; McCullagh A; McDonald T; Selvadurai H; McIntyre P; Oftadeh S; Ranganathan S; Saunders T; Suresh S; Wainwright C; Wilson A; Wong M; Jaffe A; Snelling T, 2022, Real World Impact of 13vPCV in Preventing Invasive Pneumococcal Pneumonia in Australian Children: A National Study, http://dx.doi.org/10.2139/ssrn.4068377

Stick SM; Foti A; Ware RS; Tiddens HAWM; Clements BS; Armstrong DS; Selvadurai H; Tai A; Cooper PJ; Byrnes CA; Belessis Y; Wainwright C; Jaffe A; Robinson P; Saiman L; Sly PD, 2021, The Effect of Azithromycin on Structural Lung Disease in Infants with Cystic Fibrosis (COMBAT CF): A Phase 3, Randomised, Double-Blind, Placebo-Controlled Clinical Trial, http://dx.doi.org/10.2139/ssrn.3990938

Allan KM; Zhang S; Wong SL; Capraro A; McCarron A; Skinner D; Kardia E; Zheng Y; Zhong L; Ng C-A; Bell JL; Farrow N; Umashankar B; Banks C; Herbert C; Kilian KA; Pandzic E; Vittorio O; Vandenberg JI; Lock JG; Jaffe A; Donnelley M; Parsons D; Woodworth BA; Cho D-Y; Waters SA, Gene-Corrected Basal Cells Restore CFTR In Vitro; Transplants Regenerate Epithelium in a Preclinical Sinus Model, http://dx.doi.org/10.1101/2025.07.21.666023

Dayaratne WL; Torres-Cadena R; Schmitt BP; Westrick EM; Jaffe A, Hybrid bronzes: mixed-valence organic-inorganic metal oxides as a tunable material platform, http://dx.doi.org/10.26434/chemrxiv-2023-v6h2h

Wong SL; Awatade NT; Astore MA; Allan KM; Carnell MJ; Slapetova I; Chen P-C; Capraro A; Fawcett LK; Whan RM; Griffith R; Ooi CY; Kuyucak S; Jaffe A; Waters SA, In silico and functional characterisation of an ultra-rare CFTR mutation identifies novel lasso motif interactions regulating channel gating, http://dx.doi.org/10.1101/2021.12.12.472297

Fawcett LK; Chew ZA; Schneider-Futschik EK; Allan KM; Patel HR; Jaffe A; Waters SA, INTEGRATING GENOMIC AND FUNCTIONAL TESTING TO IMPROVE CFTR MODULATOR RESPONSE PREDICTION IN CHILDREN WITH CYSTIC FIBROSIS, http://dx.doi.org/10.1101/2025.07.09.25331152

McKnight L; Schultz A; Vidic N; Palmer E; Jaffe A, Learning to make a difference for chILD: Value creation through network collaboration and team science, http://dx.doi.org/10.22541/au.166740302.29601419/v1

Wong SL; Awatade NT; Astore MA; Allan KM; Carnell MJ; Slapetova I; Chen P-C; Setiadi J; Pandzic E; Fawcett LK; Widger JR; Whan RM; Griffith R; Ooi CY; Kuyucak S; Jaffe A; Waters SA, Molecular dynamics and theratyping in airway and gut organoids reveal R352Q-CFTR conductance defect, http://dx.doi.org/10.1101/2021.08.11.456003

Hewson CK; Capraro A; Wong SL; Pandzic E; Fernando BSM; Awatade NT; Zhong L; Hart-Smith G; Whan RM; Thomas SR; Jaffe A; Bridge WJ; Waters SA, Novel antioxidant therapy with the immediate precursor to glutathione, γ-glutamylcysteine (GGC), ameliorates LPS-induced cellular stress in an in vitro cystic fibrosis model, http://dx.doi.org/10.1101/2020.05.27.119990

Sabino LR; Kaiko GE; Dorahy D; Goodsall TT; Jaffe A; Schultz A; Waters S; Cook D; Kok H; Tong K; Totterdell J; McGree J; Snelling T; Wark PA, Organoid Guided N-of-1 (ORIGIN-1) Clinical Trial: A phase 4 study to investigate if people with cystic fibrosis with rare non-F508del CFTR mutations with an in-vitro response to Elexacaftor/ Tezacaftor/ Ivacaftor have a clinically meaningful response to Elexacaftor/ Tezacaftor/ Ivacaftor versus placebo., http://dx.doi.org/10.21203/rs.3.rs-7787221/v1

Homaira N; Chan M; Owens L; Thomsen A; Gray M; Chuang S; Prentice B; Belessis Y; Islam S; Foster J; Jaffe A, Parent/carers opinions about COVID-19 vaccination for children with chronic lung diseases, http://dx.doi.org/10.22541/au.170666146.66053164/v1

Coffey MJ; van Dorst J; Pushpakumara BLDU; Halim J; Hudson J; Plush L; Christi K; Foster C; Carzino R; Zajakovski N; Appleton L; Cheney J; Wood J; Monaghan SJ; Rawlinson W; Day AS; Oliver M; Ranganathan S; Selvadurai H; Wainwright C; Thomas T; Jaffe A; Ooi CY, Probiotics and the EARly Life effects on intestinal bacteria and inflammation in children with Cystic Fibrosis (The “PEARL-CF” Study), http://dx.doi.org/10.64898/2025.12.04.25341620

Hartley NA; Pugh SM; Xu Z; Leong DC; Jaffe A; Forse AC, Quinone-functionalised carbons as new materials for electrochemical carbon dioxide capture, http://dx.doi.org/10.26434/chemrxiv-2023-ls7mc-v2

Jaffe A; Ziebel M; Halat DM; Biggins N; Murphy R; Chakarawet K; Reimer JA; Long JR, Selective, High-Temperature O2 Adsorption in Chemically Reduced, Redox-Active Iron-Pyrazolate Metal–Organic Frameworks, http://dx.doi.org/10.26434/chemrxiv.9922541.v4

Jaffe A; Ziebel M; Halat DM; Biggins N; Murphy R; Chakarawet K; Reimer JA; Long JR, Selective, High-Temperature O2 Adsorption in Chemically Reduced, Redox-Active Iron-Pyrazolate Metal–Organic Frameworks, http://dx.doi.org/10.26434/chemrxiv.9922541.v3

Jaffe A; Ziebel M; Halat DM; Biggins N; Murphy R; Chakarawet K; Reimer JA; Long JR, Selective, High-Temperature O2 Adsorption in Chemically Reduced, Redox-Active Iron-Pyrazolate Metal–Organic Frameworks, http://dx.doi.org/10.26434/chemrxiv.9922541.v2

Jaffe A; Ziebel M; Halat DM; Biggins N; Murphy R; Chakarawet K; Reimer JA; Long JR, Selective, High-Temperature O2 Adsorption in Chemically Reduced, Redox-Active Iron-Pyrazolate Metal–Organic Frameworks, http://dx.doi.org/10.26434/chemrxiv.9922541

Jaffe A; Ziebel M; Halat DM; Biggins N; Murphy R; Chakarawet K; Reimer JA; Long JR, Selective, High-Temperature O2 Adsorption in Chemically Reduced, Redox-Active Iron-Pyrazolate Metal–Organic Frameworks, http://dx.doi.org/10.26434/chemrxiv.9922541.v1

Umashankar B; Capraro A; Vijayan A; Wong SL; Nielsen BU; Zhong L; Raftery M; Allan K; Ooi CY; Sivam S; Visser S; Prentice BJ; Fawcett L; Kovacevic Z; Eliasson L; Faurholt-Jepsen D; Jaffe A; Shaw JA; Vafaee F; Waters SA, Serum Exosomal Multi-Omic Signatures Stratify Glucose Tolerance in Cystic Fibrosis and Reveal Partial Therapeutic Reprogramming by CFTR Modulators, http://dx.doi.org/10.1101/2025.07.07.25331056

Awatade NT; Wong SL; Pandzic E; Slapetova I; Capraro A; Zhong L; Turgutoglu N; Fawcett LK; Whan RM; Jaffe A; Waters SA, Significant functional differences despite morphological and molecular similarity in fully differentiated matched Conditionally Reprogrammed (CRC) and Feeder free dual SMAD inhibited expanded human nasal epithelial cells, http://dx.doi.org/10.1101/2020.05.29.120006

Singh J; Jaffe A; Schultz A; Selvadurai H, Surfactant Protein Deficiency Syndrome in Childhood Interstitial Lung Disease, http://dx.doi.org/10.22541/au.160037735.51250770

Chan C; Coffey M; Murphy C; McKay I; Abdu J; Paida K; Tam R; Wrigley-Carr H; Prentice B; Owens L; Belessis Y; Chuang S; Jaffe A; van Dorst J; Ooi CY, The Prevalence of pks+ E. coli in Cystic Fibrosis, http://dx.doi.org/10.20944/preprints202502.0874.v1

Stiboy E; Chan M; Islam MS; L GS; Lui K; Jaffe A; Homaira N, Variation in clinical practice guidelines for use of palivizumab in preventing severe respiratory syncytial viral (RSV) disease in high-risk infants, http://dx.doi.org/10.22541/au.166419726.62754781/v2

Stiboy E; Chan M; Islam MS; L GS; Lui K; Jaffe A; Homaira N, Variation in clinical practice guidelines for use of palivizumab in preventing severe respiratory syncytial viral (RSV) disease in high-risk infants, http://dx.doi.org/10.22541/au.166419726.62754781/v1

Other

Strachan RE; Jaffé A, 2011, Recommendations for managing paediatric empyema thoracis

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