By Professor Caroline Rae

Journal articles

Pride NB; Payne J; Webster RI; Shores EA; Rae CD; North K, 2010, 'Corpus callosum morphology and its relationship to cognitive function in neurofibromatosis type 1', Journal of Child Neurology, 25, pp. 834 - 841

Nasrallah F; Maher A; Hanrahan JR; Balcar VJ; Rae CD, 2010, 'gamma-hydroxybutyrate and the GABAergic footprint: a metabolomic approach to unpicking the actions of GHB', Journal of Neurochemistry, 115, pp. 58 - 67

Sonnewald U; Rae CD, 2010, 'Pyruvate carboxylation in different model systems studied by 13C MRS', Neurochemical Research, 35, pp. 1916 - 1921

Rae CD; Bartlett D; Yang Q; Walton D; Denotti A; Sachinwalla T; Grunstein R, 2009, 'Dynamic changes in brain bioenergetics during obstructive sleep apnea', Journal of Cerebral Blood Flow and Metabolism, 29, pp. 1421 - 1428

Rae CD; Nasrallah F; Broer S, 2009, 'Metabolic effects of blocking lactate transport in brain cortical tissue slices using an inhibitor specific to MCT1 and MCT2', Neurochemical Research, 34, pp. 1783 - 1791, http://dx.doi.org/10.1007/s11064-009-9973-0

Teng R; Junankar P; Bubb W; Rae CD; Mercier P; Kirk K, 2009, 'Metabolite profiling of the intraerythrocytic malaria parasite Plasmodium falciparum by 1H NMR spectroscopy', NMR in Biomedicine, 22, pp. 292 - 302, http://dx.doi.org/10.1002/nbm.1323

Rae CD; Nasrallah F; Griffin J; Balcar VJ, 2009, 'Now I know my ABC. A systems neurochemistry and functional metabolomic approach to understanding the GABAergic system', Journal of Neurochemistry, 109, pp. 109 - 116, http://dx.doi.org/10.1111/j.1471-4159.2009.05803.x

Rae CD, 2009, 'RE: Magnetic resonance spectroscopy of the brain: review of metabolites and clinical applications', Clinical Radiology, 64, pp. 1042 - 1043

Nguyen K; Shin J; Rae CD; Nanitsos E; Acosta G; Pow D; Buljan V; Bennett MR; Else P; Balcar VJ, 2009, 'Rottlerin inhibits (Na+, K+)-ATPase activity in brain tissue and alters D-aspartate dependent redistribution of glutamate transporter GLAST in cultured astrocytes', Neurochemical Research, 34, pp. 1767 - 1774

Nasrallah F; Griffin J; Balcar VJ; Rae CD, 2009, 'Understanding your inhibitions: Effects of GABA and GABAA receptor modulation on brain cortical metabolism', Journal of Neurochemistry, 108, pp. 57 - 71, http://dx.doi.org/10.1111/j.1471-4159.2008.05742.x

Rae CD; Henry RG, 2008, 'Mind meld: collaborative approaches to understanding how we all think', Brain Imaging and Behavior, 2, pp. 343 - 349, http://dx.doi.org/10.1007/s11682-008-9036-1

Nasrallah F; Garner B; Ball GE; Rae CD, 2008, 'Modulation of brain metabolism by very low concentrations of the commonly used drug delivery vehicle dimethyl sulfoxide (DMSO)', Journal of Neuroscience Research, 86, pp. 208 - 214, http://dx.doi.org/10.1002/jnr.21477

Rae C; Nasrallah FA; Griffin JL; Balcar VJ, 2008, 'Understanding your inhibitions: neuropharmacological perturbations of GABAergic systems, metabolic outcomes and network correlations.', NeuroImage, 41, pp. s - 57

Rae C, 2007, 'Piece of mind; a full systems approach is required', Behavioral and Brain Sciences, 30, pp. 167 - 168, http://dx.doi.org/10.1017/S0140525X07001276

Bröer S; Bröer A; Hansen JT; Bubb WA; Balcar VJ; Nasrallah FA; Garner B; Rae C, 2007, 'ALANINE METABOLISM, TRANSPORT AND CYCLING IN THE BRAIN', Journal of Neurochemistry, http://dx.doi.org/10.1111/j.1471-4159.2007.004654.x

Broeer S; Broeer A; Hansen J; Bubb W; Balcar VJ; Nasrallah F; Garner B; Rae CD, 2007, 'Alanine metabolism, transport, and cycling in the brain', Journal of Neurochemistry, 102, pp. 1758 - 1770

Moussa C; Rae CD; Bubb W; Griffin J; Deters N; Balcar VJ, 2007, 'Inhibitors of glutamate transport modulate distinct patterns in brain metabolism', Journal of Neuroscience Research, 85, pp. 342 - 350

Schindeler S; Ghosh-Jerath S; Thompson S; Rocca A; Joy P; Kemp A; Rae CD; Green K; Wilcken B; Christodoulou J, 2007, 'The effects of large neutral amino acid supplements in PKU: An MRS and neuropsychological study', Molecular Genetics and Metabolism, 91, pp. 48 - 54, http://dx.doi.org/10.1016/j.ymgme.2007.02.002

Nasrallah F; Griffin J; Balcar VJ; Rae CD, 2007, 'Understanding your inhibitions: modulation of brain cortical metabolism by GABAb receptors', Journal of Cerebral Blood Flow and Metabolism, 27, pp. 1510 - 1520, http://dx.doi.org/10.1038/sj.jcbfm.9600453

Rae CD; Moussa C; Griffin J; Parekh S; Bubb W; Hunt N; Balcar V, 2006, 'A metabolomic approach to ionotropic glutamate receptor subtype function: a nuclear magnetic resonance in vitro investigation', Journal of Cerebral Blood Flow and Metabolism, 26, pp. 1005 - 1017

Parekh S; Bubb W; Hunt NH; Rae CD, 2006, 'Brain metabolic markers reflect susceptibility status in cytokine gene knockout mice with murine cerebral malaria', International Journal for Parasitology, 36, pp. 1409 - 1418, http://dx.doi.org/10.1016/j.ijpara.2006.07.004

Hunt NH; Golenser J; Chan-Ling T; Parekh S; Rae CD; Potter SS; Medana IM; Miu J; Ball HJ, 2006, 'Immunopathogenesis of cerebral malaria', International Journal for Parasitology, 36, pp. 569 - 582, http://dx.doi.org/10.1016/j.ijpara.2006.02.016

Rae CD; Moussa CE; Griffin JL; Bubb WA; Wallis T; Balcar VJ, 2005, 'Group I and II metabotropic glutamate receptors alter brain cortical metabolic and glutamate/glutamine cycle activity: a 13C NMR spectroscopy and metabolomic study', Journal of Neurochemistry, 92, pp. 405 - 416, http://dx.doi.org/10.1111/j.1471-4159.2004.02880.x

Dunne VG; Bhattachayya S; Besser M; Rae CD; Griffin JL, 2005, 'Metabolites from cerebrospinal fluid in aneurysmal subarachnoid haemorrhage correlate with vasospasm and clinical outcome: a pattern-recognition 1H NMR study', NMR in Biomedicine, 18, pp. 24 - 33, http://dx.doi.org/10.1002/nbm.918

Parekh S; Moussa C; Balcar VJ; Hunt NH; Bubb W; Rae CD, 2005, 'Quinolinic acid, kynurenic acid and dserine stimulate brain metabolism', Journal of Neurochemistry, 94, pp. 58 - 58

Parry L; Shores A; Rae CD; Kemp A; Waugh M-C; Chaseling R; Joy P, 2004, 'An investigation of neuronal integrity in severe paediatric traumatic brain injury', Child Neuropsychology, 10, pp. 248 - 261, http://dx.doi.org/10.1080/09297040490909279

Rae CD; McQuillan JA; Parekh SB; Bubb WA; Weiser S; Balcar VJ; Hansen AM; Ball HJ; Hunt NH, 2004, 'Brain gene expression, metabolism and bioenergetics; interrelationships in murine models of malaria', The FASEB Journal, 18, pp. 499 - 510, http://www.fasebj.org/cgi/reprint/18/3/499.pdf

Nanitsos EK; Acosta GB; Saihara Y; Stanton D; Liao LP; Shin J; Rae CD; Balcar VJ, 2004, 'Effects of glutamate transport substrates and glutamate receptor ligands on the activity of (Na+,K+)-ATPase in brain tissue in vitro', Clinical and Experimental Pharmacology and Physiology, 31, pp. 762 - 769, http://dx.doi.org/10.1111/j.1440-1681.2004.04090.x

Rae CD; Joy P; Harasty J; Kemp A; Kuan S; Christodoulou J; Cowell CT; Coltheart M, 2004, 'Enlarged temporal lobes in Turner syndrome. An X-chromosome effect?', Cerebral cortex, 14, pp. 156 - 164, http://dx.doi.org/10.1093/cercor/bhg114

Wallis T; Bubb WA; McQuillan JA; Balcar VJ; Rae CD, 2004, 'For want of a nail. Ramifications of a single gene deletion, dystrophin, in the brain of the mouse', Frontiers in Bioscience, 1, pp. 74 - 84, http://dx.doi.org/10.2741/1209

Bartlett D; Rae CD; Thompson CH; Byth K; Joffe D; Enright T; Grunstein RR, 2004, 'Hippocampal area metabolites relate to severity and cognitive functionin obstructive sleep apnea', Sleep Medicine, 5, pp. 593 - 596

Rae CD; Scott RB; Lee M; Simpson JM; Hines N; Paul C; Anderson M; Karmiloff-Smith A; Styles P; Radda GK, 2003, 'Brain bioenergetics and cognitive ability', Developmental Neuroscience, 25, pp. 324 - 331, http://dx.doi.org/10.1159/000073509

Stanton D; Liao LP; Moussa CE; Bubb WA; Rae CD; Balcar VJ, 2003, 'Can inhibition of glutamate transport contribute to the action of neuroleptics?', Psychiatrie, 7, pp. 6 - 11

Griffin JL; Keun H; Richter C; Moskau D; Rae CD; Nicholson JK, 2003, 'Compartmentation of metabolism probed by [2-13C]alanine: Improved 13C NMR sensitivity using a CryoProbe detects evidence of a glial metabolon', Neurochemistry International, 42, pp. 93 - 99, http://dx.doi.org/10.1016/S0197-0186(02)00064-5

Rooney KB; Bryson JM; Digney AL; Rae CD; Thompson CH, 2003, 'Creatine supplementation affects glucose homeostasis but not insulin secretion in vegetarians', Annals of Nutrition and Metabolism, 47, pp. 11 - 15, http://dx.doi.org/10.1159/000068908

Rae CD; Hare N; Bubb WA; McEwen SR; Broer A; McQuillan JA; Balcar VJ; Conigrave AD; Broer S, 2003, 'Inhibition of glutamine transport depletes glutamate and GABA neurotransmitter pools; further evidence for metabolic compartmentation', Journal of Neurochemistry, 85, pp. 503 - 514, http://dx.doi.org/10.1046/j.1471-4159.2003.01713.x

Valenzuela MJ; Jones M; Wen W; Rae CD; Graham SL; Schnier R; Sachdev PS, 2003, 'Memory training alters hippocampal neurochemistry in healthy elderly', Neuroreport, 14, pp. 1333 - 1337, http://journals.lww.com/neuroreport/Abstract/2003/07180/Memory_training_alters_hippocampal_neurochemistry.10.aspx

Rae CD; Digney AL; McEwen SR; Bates TC, 2003, 'Oral creatine monohydrate supplementation improves cognitive performance; a placebo-controlled, double-blind cross-over trial', Proceedings of the Royal Society of London Series B - Biological Sciences, 270, pp. 2147 - 2150, http://dx.doi.org/10.1098/rspb.2003.2492

Moussa CEH; Mitrovic AD; Vandenberg RJ; Provis T; Rae C; Bubb WA; Balcar VJ, 2002, 'Effects of L-glutamate transport inhibition by a conformationally restricted glutamate analogue (2S,1'S,2'R)-2-(Carboxycyclopropyl)glycine (L-CCG III) on metabolism in brain tissue in vitro analysed by NMR spectroscopy', Neurochemical Research, 27, pp. 27 - 35, http://dx.doi.org/10.1023/A:1014842303583

Rae C; Griffin JL; Blair DH; Bothwell JH; Bubb WA; Maitland A; Head S, 2002, 'Abnormalities in brain biochemistry associated with lack of dystrophin: Studies of the mdx mouse', Neuromuscular Disorders, 12, pp. 121 - 129, http://dx.doi.org/10.1016/S0960-8966(01)00253-X

Rae C; Blair DH; Griffin JL; Bothwell JHF; Bubb WA; Maitland A; Head S, 2002, 'Brain biochemical abnormalities associated with lack of dystrophin; studies in the mdx mouse.', Neuromuscular Disorders, 12, pp. 121 - 129

Anderson JL; Head SI; Rae CD; Morley JW, 2002, 'Brain Function in Duchenne muscular dystrophy', Brain, 125, pp. 4 - 13

Bothwell JH; Rae C; Dixon RM; Styles P; Bhakoo KK, 2001, 'Hypo-osmotic swelling-activated release of organic osmolytes in brain slices: Implications for brain oedema in vivo', Journal of Neurochemistry, 77, pp. 1632 - 1640, http://dx.doi.org/10.1046/j.1471-4159.2001.00403.x

Sanni LA; Rae C; Maitland A; Stocker R; Hunt NH, 2001, 'Is ischemia involved in the pathogenesis of murine cerebral malaria?', American Journal of Pathology, 159, pp. 1105 - 1112, http://dx.doi.org/10.1016/S0002-9440(10)61786-5

Hansen PE; Skibsted U; Nissen J; Rae CD; Kuchel PW, 2001, '1H NMR of compounds with low water solubility in the presence of erythrocytes. Effects of emulsion phase separation.', European Journal of Biophysics, 30, pp. 69 - 74

Harasty JA; Thompson C; Stein J, 2001, 'Cerebellar morphology in developmental dyslexia', Neuropsychologia

Griffin JL; Williams HJ; Sang E; Clarke K; Rae C; Nicholson JK, 2001, 'Metabolic profiling of genetic disorders: a multi-tissue 1H NMR spectroscopic and pattern recognition study into dystrophic tissue.', Analytical Biochemistry, 293, pp. 16 - 21

Rae C; Lawrance ML; Dias LS; Provis T; Bubb WA; Balcar VJ, 2000, 'Strategies for studies of neurotoxic mechanisms involving deficient transport of L-glutamate: Antisense knockout in rat brain in vivo and changes in the neurotransmitter metabolism following inhibition of glutamate transport in guinea pig brain slices', Brain Research Bulletin, 53, pp. 373 - 381, http://dx.doi.org/10.1016/S0361-9230(00)00372-5

Maitland AT; Rae C; Bubb WA; Hunt NH, 2000, 'Dichloroacetate (DCA) Decreases Brain Lactate But Increases Brain Glutamate in Murine Cerebral Malaria', Biochemical Society Transactions, 28, pp. A455 - A455, http://dx.doi.org/10.1042/bst028a455

Staines HM; Rae C; Kirk K, 2000, 'Increased permeability of the malaria-infected erythrocyte to organic cations', Biochimica et Biophysica Acta - Biomembranes, 1463, pp. 88 - 98, http://dx.doi.org/10.1016/S0005-2736(99)00187-X

Back to profile page