Select Publications
Book Chapters
2001, 'Mammery Gland Development', in Horseman ND (ed.), Prolactin, Kluwer Academic Publishers, Boston, pp. 219 - 232
,Journal articles
2022, 'Activation of the viral sensor oligoadenylate synthetase 2 (Oas2) prevents pregnancy-driven mammary cancer metastases', Breast Cancer Research, 24, http://dx.doi.org/10.1186/s13058-022-01525-z
,2022, 'Epigenome erosion and SOX10 drive neural crest phenotypic mimicry in triple-negative breast cancer', npj Breast Cancer, 8, http://dx.doi.org/10.1038/s41523-022-00425-x
,2022, 'ALTEN: A High-Fidelity Primary Tissue-Engineering Platform to Assess Cellular Responses Ex Vivo', Advanced Science, 9, http://dx.doi.org/10.1002/advs.202103332
,2022, 'TNFAIP3 Reduction-of-Function Drives Female Infertility and CNS Inflammation', Frontiers in Immunology, 13, http://dx.doi.org/10.3389/fimmu.2022.811525
,2021, 'NSG-Pro mouse model for uncovering resistance mechanisms and unique vulnerabilities in human luminal breast cancers', Science Advances, 7, http://dx.doi.org/10.1126/sciadv.abc8145
,2021, 'Single-cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype', Cell Reports, 35, http://dx.doi.org/10.1016/j.celrep.2021.108945
,2021, 'Inhibitor of Differentiation 4 (ID4) represses mammary myoepithelial differentiation via inhibition of HEB', iScience, 24, http://dx.doi.org/10.1016/j.isci.2021.102072
,2020, 'Id Proteins Promote a Cancer Stem Cell Phenotype in Mouse Models of Triple Negative Breast Cancer via Negative Regulation of Robo1', Frontiers in Cell and Developmental Biology, 8, http://dx.doi.org/10.3389/fcell.2020.00552
,2020, 'Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer', Breast Cancer Research, 22, http://dx.doi.org/10.1186/s13058-020-01306-6
,2020, 'MCL-1 antagonism enhances the anti-invasive effects of dasatinib in pancreatic adenocarcinoma', Oncogene, 39, pp. 1821 - 1829, http://dx.doi.org/10.1038/s41388-019-1091-0
,2020, 'ELF5 modulates the estrogen receptor cistrome in breast cancer', PLoS Genetics, 16, http://dx.doi.org/10.1371/journal.pgen.1008531
,2020, 'Inhibitor of Differentiation 4 (ID4) represses myoepithelial differentiation of mammary stem cells through its interaction with HEB', , http://dx.doi.org/10.1101/2020.04.06.026963
,2019, 'Characterisation of developmental pathways that drive metastatic progression of breast cancer at single cell resolution', Oncology Abstracts, http://dx.doi.org/10.1530/oncolabs.1.p022
,2019, 'Flicking the switch off, targeting MCL-1 in the treatment of breast and prostate cancer', Oncology Abstracts, http://dx.doi.org/10.1530/oncolabs.1.p038
,2019, 'Novel role of CBF[beta] as a regulator of breast cancer phenotype, progression and metastasis', Oncology Abstracts, http://dx.doi.org/10.1530/oncolabs.1.p037
,2019, 'The proliferative and apoptotic landscape of basal-like breast cancer', International Journal of Molecular Sciences, 20, http://dx.doi.org/10.3390/ijms20030667
,2019, 'Single cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype', , http://dx.doi.org/10.1101/624890
,2018, 'Single-cell transcriptomics in cancer immunobiology: The future of precision oncology', Frontiers in Immunology, 9, http://dx.doi.org/10.3389/fimmu.2018.02582
,2018, 'Myeloid cell leukemia 1 (MCL-1), an unexpected modulator of protein kinase signaling during invasion', Cell Adhesion and Migration, 12, pp. 513 - 523, http://dx.doi.org/10.1080/19336918.2017.1393591
,2018, 'Static droplet array for culturing single live adherent cells in an isolated chemical microenvironment', Lab on a Chip, 18, pp. 2156 - 2166, http://dx.doi.org/10.1039/c8lc00403j
,2018, 'A novel role for the HLH protein Inhibitor of Differentiation 4 (ID4) in the DNA damage response in basal-like breast cancer.', BIORXIV, http://dx.doi.org/10.1101/281196
,2017, 'Andy's Algorithms: New automated digital image analysis pipelines for FIJI', Scientific Reports, 7, http://dx.doi.org/10.1038/s41598-017-15885-6
,2017, 'A mutation in the viral sensor 2’-5’-oligoadenylate synthetase 2 causes failure of lactation', PLoS Genetics, 13, pp. e1007072, http://dx.doi.org/10.1371/journal.pgen.1007072
,2017, 'A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts', Cell Reports, 21, pp. 274 - 288, http://dx.doi.org/10.1016/j.celrep.2017.09.022
,2017, 'Erratum: The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy (Endocrine-related cancer (2017) 24 4 (R123-R144) PII: ERC160404e)', Endocrine-related cancer, 24, pp. X1, http://dx.doi.org/10.1530/ERC-16-0404e
,2017, 'Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis', Science Translational Medicine, 9, http://dx.doi.org/10.1126/scitranslmed.aai8504
,2017, 'The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy', Endocrine-Related Cancer, 24, pp. R123 - R144, http://dx.doi.org/10.1530/ERC-16-0404
,2016, 'MCL-1 inhibition provides a new way to suppress breast cancer metastasis and increase sensitivity to dasatinib', Breast Cancer Research, 18, http://dx.doi.org/10.1186/s13058-016-0781-6
,2016, 'ELF5 isoform expression is tissue-specific and significantly altered in cancer', Breast Cancer Research, 18, http://dx.doi.org/10.1186/s13058-015-0666-0
,2016, 'Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue', Cell Reports, 14, pp. 152 - 167, http://dx.doi.org/10.1016/j.celrep.2015.12.020
,2015, 'ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells', PLoS Biology, 13, http://dx.doi.org/10.1371/journal.pbio.1002330
,2015, 'LRGUK-1 Is Required for Basal Body and Manchette Function during Spermatogenesis and Male Fertility', PLoS Genetics, 11, http://dx.doi.org/10.1371/journal.pgen.1005090
,2015, 'ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype', NATURE COMMUNICATIONS, 6, http://dx.doi.org/10.1038/ncomms7548
,2015, 'HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse', PLoS Genetics, 11, http://dx.doi.org/10.1371/journal.pgen.1005620
,2015, 'Correction: HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse.', PLoS Genet, 11, pp. e1005782, http://dx.doi.org/10.1371/journal.pgen.1005782
,2014, 'The mammary cellular hierarchy and breast cancer', Cellular and Molecular Life Sciences, 71, pp. 4301 - 4324, http://dx.doi.org/10.1007/s00018-014-1674-4
,2014, 'Profiling the tyrosine phosphoproteome of different mouse mammary tumour models reveals distinct, model-specific signalling networks and conserved oncogenic pathways', Breast Cancer Research, 16, http://dx.doi.org/10.1186/s13058-014-0437-3
,2014, 'Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer', Cancer Research, 74, pp. 5277 - 5286, http://dx.doi.org/10.1158/0008-5472.CAN-14-0053
,2014, 'Acquired convergence of hormone signaling in breast cancer: ER and PR transition from functionally distinct in normal breast to predictors of metastatic disease', Oncotarget, 5, pp. 8651 - 8664, http://dx.doi.org/10.18632/oncotarget.2354
,2014, 'RNAi-mediated stathmin suppression reduces lung metastasis in an orthotopic neuroblastoma mouse model', Oncogene, 33, pp. 882 - 890, http://dx.doi.org/10.1038/onc.2013.11
,2013, 'ELF5, normal mammary development and the heterogeneous phenotypes of breast cancer', BREAST CANCER MANAGEMENT, 2, pp. 489 - 498, http://dx.doi.org/10.2217/BMT.13.50
,2013, 'A Missense Mutation in the Transcription Factor ETV5 Leads to Sterility, Increased Embryonic and Perinatal Death, Postnatal Growth Restriction, Renal Asymmetry and Polydactyly in the Mouse', PLoS ONE, 8, http://dx.doi.org/10.1371/journal.pone.0077311
,2013, 'c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer', Oncogene, http://dx.doi.org/10.1038/onc.2013.368
,2013, 'BCL-2 hypermethylation is a potential biomarker of sensitivity to antimitotic chemotherapy in endocrine-resistant breast cancer', Molecular Cancer Therapeutics, 12, pp. 1874 - 1885, http://dx.doi.org/10.1158/1535-7163.MCT-13-0012
,2013, 'RBM5 Is a Male Germ Cell Splicing Factor and Is Required for Spermatid Differentiation and Male Fertility', PLoS Genetics, 9, pp. e1003628, http://dx.doi.org/10.1371/journal.pgen.1003628
,2013, 'Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells', Development (Cambridge), 140, pp. 1397 - 1401, http://dx.doi.org/10.1242/dev.088948
,2013, 'Functional characterization of cancer-associated Gab1 mutations', Oncogene, 32, pp. 2696 - 2702, http://dx.doi.org/10.1038/onc.2012.271
,2013, 'KIBRA exhibits MST-independent functional regulation of the Hippo signaling pathway in mammals', Oncogene, 32, pp. 1821 - 1830, http://dx.doi.org/10.1038/onc.2012.196
,2012, 'An essential role for katanin p80 and microtubule severing in male gamete production', PLoS Genetics, 8, pp. e1002698, http://dx.doi.org/10.1371/journal.pgen.1002698
,