By Professor Christopher John Ormandy

Journal articles

McClellan KA; Robertson FG; Kindblom J; Wennbo H; Tornell J; Bouchard B; Kelly PA; Ormandy CJ, 2001, 'Investigation of the role of prolactin in the development and function of the lacrimal and Harderian glands using genetically modified mice', Investigative Ophthalmology and Visual Science, pp. 23 - 30

Craven AJ; Ormandy CJ; Robertson FG; Wilkins RJ; Kelly PA; Nixon AJ; Pearson AJ, 2001, 'Prolactin signaling influences the timing mechanism of the hair follicle: analysis of molting cycles in prolactin receptor knockout mice.', Endocrinology, 142, pp. 2533 - 2539

Linderman GJ; Wittlin S; Naylor MJ; Santamaria M; Zhang J; Starr R; Hilton D; Alexander WS; Ormandy CJ; Visvader J, 2001, 'SOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor deficient mice.', Genes and Development, 15, pp. 1631 - 1639

Binart N; Ormandy CJ; Kelly PA, 2000, 'Mammary gland development and the prolactin receptor', Advances in Experimental Medicine and Biology, 480, pp. 85 - 92

Binart N; Helloco C; Ormandy CJ; Barra J; Cle Ment-Lacroix P; Baran N; Kelly PA, 2000, 'Rescue of Preimplantatory Egg Development and Embryo Implantation in Prolactin Receptor-Deficient Mice after Progesterone Administration.', Endocrinology, 141, pp. 2691 - 2697, http://dx.doi.org/10.1210/endo.141.7.7568

Binart N; Helloco C; Ormandy CJ; Barra J; Clément-Lacroix P; Baran N; Kelly PA, 2000, 'Rescue of preimplantatory egg development and embryo implantation in prolactin receptor-deficient mice after progesterone administration.', Endocrinology, 141, pp. 2691 - 2697, http://dx.doi.org/10.1210/endo.141.7.7568

Goffin V; Binart N; Clément-Lacroix P; Bouchard B; Bole-Feysot C; Edery M; Lucas BK; Touraine P; Pezet A; Maaskant R; Pichard C; Helloco C; Baran N; Favre H; Bernichtein S; Allamando A; Ormandy C; Kelly PA, 1999, 'From the molecular biology of prolactin and its receptor to the lessons learned from knockout mice models', Genetic Analysis - Biomolecular Engineering, 15, pp. 189 - 201, http://dx.doi.org/10.1016/S1050-3862(99)00025-X

Bouchard B; Ormandy CJ; Di Santo JP; Kelly PA, 1999, 'Immune system development and function in prolactin receptor-deficient mice', Journal of Immunology, 163, pp. 576 - 582

Cle Ment-Lacroix P; Ormandy C; Lepescheux LN; Ammann P; Damotte D; Goffin V; Bouchard B; Amling M; Gaillard-Kelly M; Binart N; Baron R; Kelly PA, 1999, 'Osteoblasts Are a New Target for Prolactin: Analysis of Bone Formation in Prolactin Receptor Knockout Mice* *This work was supported in part by grants from Hoechst Marion Roussel, Inc.', Endocrinology, 140, pp. 96 - 105, http://dx.doi.org/10.1210/endo.140.1.6436

Clement-Lacroix P; Ormandy C; Lepescheux L; Ammann P; Damotte D; Goffin V; Bouchard B; Amling M; Gaillard-Kelly M; Binart N; Baron R; Kelly PA, 1999, 'Osteoblasts Are a New Target for Prolactin', Obstetrical & Gynecological Survey, 54, pp. 383 - 384, http://dx.doi.org/10.1097/00006254-199906000-00018

Clément-Lacroix P; Ormandy C; Lepescheux L; Ammann P; Damotte D; Goffin V; Bouchard B; Amling M; Gaillard-Kelly M; Binart N; Baron R; Kelly PA, 1999, 'Osteoblasts are a new target for prolactin: analysis of bone formation in prolactin receptor knockout mice.', Endocrinology, 140, pp. 96 - 105, http://dx.doi.org/10.1210/endo.140.1.6436

Brisken C; Kaur S; Chavarria TE; Binart N; Sutherland RL; Weinberg RA; Kelly P; Ormandy CJ, 1999, 'Prolactin controls mammary gland development via direct and indirect mechanisms', Developmental Biology, pp. 96 - 106

Wynick D; Small CJ; Bacon A; Holmes FE; Norman M; Ormandy CJ; Kilic E; Kerr NCH; Ghatei M; Talamantes F; Bloom SR; Pachnis V, 1998, 'Galanin regulates prolactin release and lactotroph proliferation', Proceedings of the National Academy of Sciences of the United States of America, 95, pp. 12671 - 12676, http://dx.doi.org/10.1073/pnas.95.21.12671

Lucas BK; Ormandy CJ; Binart N; Bridges RS; Kelly PA, 1998, 'Null Mutation of the Prolactin Receptor Gene Produces a Defect in Maternal Behavior', Endocrinology, 139, pp. 4102 - 4107, http://dx.doi.org/10.1210/endo.139.10.6243

Goffin V; Bouchard B; Ormandy CJ; Weimann E; Ferrag F; Touraine P; Bole-Feysot C; Maaskant RA; Clement-Lacroix P; Edery M; Binart N; Kelly PA, 1998, 'Prolactin: A hormone at the crossroads of neuroimmunoendocrinology', Annals of the New York Academy of Sciences, 840, pp. 498 - 509, http://dx.doi.org/10.1111/j.1749-6632.1998.tb09588.x

Ormandy CJ; Binart N; Helloco C; Kelly PA, 1998, 'Mouse prolactin receptor gene: Genomic organization reveals alternative promoter usage and generation of isoforms via alternative 3'-exon splicing', DNA and Cell Biology, 17, pp. 761 - 770, http://dx.doi.org/10.1089/dna.1998.17.761

Lucas BK; Ormandy CJ; Binart N; Bridges RS; Kelly PA, 1998, 'Null mutation of the prolactin receptor gene produces a defect in maternal behavior', Endocrinology, 139, pp. 4102 - 4107, http://dx.doi.org/10.1210/endo.139.10.6243

Ormandy CJ; Lee CC; Ormandy HF; Fantl V; Shine J; Peters G; Sutherland RL, 1998, 'Amplification, expression and steroid regulation of the preprogalanin gene in human breast cancer', Cancer research, pp. 1353 - 1357

Ormandy CJ; Hui R; Sutherland RL, 1998, 'Galanin and 11q13 amplification in human breast cancer', Biotech Lab Int, pp. 14 - 16

Kelly PA; Ormandy CJ; Bôle-Feysot C; Maaskant R; Freemark M; Binart N, 1998, 'Prolactin receptors and embryonic development: Gene expression and knockout studies', Placenta, 19, pp. 13 - 21, http://dx.doi.org/10.1016/s0143-4004(98)80003-9

Bignon C; Binart N; Ormandy C; Schuler LA; Kelly PA; Djiane J, 1997, 'Long and short forms of the ovine prolactin receptor: cDNA cloning and genomic analysis reveal that the two forms arise by different alternative splicing mechanisms in ruminants and in rodents', Journal of Molecular Endocrinology, 19, pp. 109 - 120, http://dx.doi.org/10.1677/jme.0.0190109

Ormandy CJ; Camus A; Barra J; Damotte D; Lucas B; Buteau H; Edery M; Brousse N; Babinet C; Binart N; Kelly PA, 1997, 'Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse', Genes and Development, 11, pp. 167 - 178, http://dx.doi.org/10.1101/gad.11.2.167

Ormandy CJ; Binart N; Kelly PA, 1997, 'Mammary gland development in prolactin receptor knockout mice.', Journal of mammary gland biology and neoplasia, 2, pp. 355 - 364, http://dx.doi.org/10.1023/A:1026395229025

Ormandy CJ; Hall R; Manning DL; Robertson JF; Blamey RW; Kelly P; Nicholson RI; Sutherland RL, 1997, 'Coexpression and cross-regulation of the prolactin receptor and sex steroid hormone receptors in Breast cancer', Journal of Clinical Endocrinology and Metabolism, pp. 3692 - 3699

Binart N; Ormandy C; Kelly PA, 1997, 'Le récepteur de la prolactine : une molécule-clé de la reproduction ?', médecine/sciences, 13, pp. 734 - 734, http://dx.doi.org/10.4267/10608/451

Lee CSL; DeFazio A; Ormandy CJ; Sutherland RL, 1996, 'Inverse regulation of oestrogen receptor and epidermal growth factor receptor genbe expression in MCF-7 breast cancer cells treated with phorbol ester', Journal of Steroid Biochemistry and Molecular Biology, 58, pp. 267 - 275, http://dx.doi.org/10.1016/0960-0760(96)00039-8

Møldrup A; Ormandy C; Nagano M; Murthy K; Banville D; Tronche F; Kelly PA, 1996, 'Differential promoter usage in prolactin receptor gene expression: hepatocyte nuclear factor 4 binds to and activates the promoter preferentially active in the liver.', Mol Endocrinol, 10, pp. 661 - 671, http://dx.doi.org/10.1210/mend.10.6.8776726

Manning DL; McClelland RA; Knowlden JM; Bryant S; Gee JMW; Green CD; Robertson JF; Blamey RW; Sutherland RL; Ormandy CJ; Nicholson RI, 1995, 'Differential expression of oestrogen regulated genes in breast cancer', Acta Oncologica, 34, pp. 641 - 646, http://dx.doi.org/10.3109/02841869509094041

Kelly PA; Edery M; Finidori J; Postel-Vinay MC; Gougon L; Ali S; Dinerstein H; Sotiropoulos A; Lochnan H; Ferrag F; Lebrun JJ; Ormandy C; Buteau H; Esposito N; Vincent V; Möldrup A, 1994, 'Receptor Domains Involved in Signal Transduction of Prolactin and Growth Hormone', Proceedings of the Society for Experimental Biology and Medicine, 206, pp. 280 - 283, http://dx.doi.org/10.3181/00379727-206-43759

Ormandy CJ; Sutherland RL, 1993, 'At the cutting edge - Mechanisms of prolactin receptor regulation in mammary gland', Molecular and Cellular Endocrinology, 91, http://dx.doi.org/10.1016/0303-7207(93)90247-H

Roman SD; Clarke CL; Ormandy CJ, 1993, 'Estradiol Induction of Retinoic Acid Receptors in Human Breast Cancer Cells', Cancer Research, 53, pp. 5940 - 5945

Ormandy CJ; Sutherland RL, 1993, 'Mechanisms of prolactin receptor regulation in mammary gland', Molecular and Cellular Endocrinology, 91, http://dx.doi.org/10.1016/0303-7207(93)90247-H

Ormandy CJ; Lee CSL; Kelly PA; Sutherland RL, 1993, 'Regulation of prolactin receptor expression by the tumour promoting phorbol ester 12‐O‐tetradecanoylphorbol‐13‐acetate in human breast cancer cells', Journal of Cellular Biochemistry, 52, pp. 47 - 56, http://dx.doi.org/10.1002/jcb.240520108

Ormandy CJ; de Fazio A; Kelly PA; Sutherland RL, 1992, 'Coordinate regulation of oestrogen and prolactin receptor expression by sodium butyrate in human breast cancer cells', Biochemical and Biophysical Research Communications, 182, pp. 740 - 745, http://dx.doi.org/10.1016/0006-291X(92)91794-Q

Ormandy CJ; Clarke CL; Kelly PA; Sutherland RL, 1992, 'Androgen regulation of prolactin‐receptor gene expression in MCF‐7 and MDA‐MB‐453 human breast cancer cells', International Journal of Cancer, 50, pp. 777 - 782, http://dx.doi.org/10.1002/ijc.2910500519

Ormandy CJ; Graham J; Kelly PA; Clarke CL; Sutherland RL, 1992, 'The Effect of Progestins on Prolactin Receptor Gene Transcription in Human Breast Cancer Cells', DNA and Cell Biology, 11, pp. 721 - 726, http://dx.doi.org/10.1089/dna.1992.11.721

Ormandy CJ; De Fazio A; Kelly PA; Sutherland RL, 1992, 'Transcriptional regulation of prolactin receptor gene expression by sodium butyrate in MCF-7 human breast cancer cells', Endocrinology, 131, pp. 982 - 984, http://dx.doi.org/10.1210/endo.131.2.1639037

Ormandy CJ; de Fazio A; Kelly PA; Sutherland RL, 1992, 'Transcriptional regulation of prolactin receptor gene expression by sodium butyrate in MCF-7 human breast cancer cells.', Endocrinology, 131, pp. 982 - 984, http://dx.doi.org/10.1210/endo.131.2.1639037

Ormandy CJ; Clarke CL; Sutherland RL, 1990, 'Solubilization and characterization of a lactogenic receptor from human placental chorion membranes', Journal of Cellular Biochemistry, 43, pp. 1 - 15, http://dx.doi.org/10.1002/jcb.240430102

Teh TC; Ormandy CJ; Surus AS; Sutherland RL; Chapman GE, 1988, 'Human growth hormone binds to lactogenic receptors in bovine, ovine and rat adrenals', Hormone and Metabolic Research, 20, pp. 278 - 281, http://dx.doi.org/10.1055/s-2007-1010815

Conference Papers

Ortega DG; Ledger A; Roden D; Cho C; Allerdice S; Lee H; Valdes-Mora F; Salomon R; Oakes S; Ormandy C, 2014, 'THE ETS TRANSCRIPTION FACTOR ELF5 IS A KEY DETERMINANT OF THE LETHAL PHENOTYPE IN LUMINAL BREAST CANCER, DRIVING THE ACQUISITION OF ANTIESTROGEN RESISTANCE AND METASTATIC ACTIVITY', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 16 - 17, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344745100030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

O'Toole S; Swarbrick A; Millar E; McLeod D; McNeil C; Qiu M; Lopez-Knowles E; Caldon E; Oakes S; Ormandy C; Morey A; Musgrove E; Henshall S; Sutherland R, 2009, 'Aberrent hedgehog signaling is an early event in breast cancer development.', in Cancer Research, American Association for Cancer Research (AACR), pp. 24 - 24, http://dx.doi.org/10.1158/0008-5472.sabcs-24

O Toole SJ; Swarbrick A; Millar E; McLeod D; Mcneil CM; Qiu MR; Lopez-Knowles E; Caldon E; Oakes SR; Ormandy CJ; Morey AL; Musgrove EA; Henshall SM; Sutherland RL, 2009, 'Aberrent hedgehog signaling is an early event in breast cancer development', in Cancer research, American Association Cancer Research, Philadelphia, PA, pp. 70S - 70S

Bhandari M; Kawamoto M; Thomas A; Carati C; Ormandy CJ; Toouli J; Saccone GT, 2007, 'Galanin knockout mice are less susceptible to caerulein-induced acute pancreatitis', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, DC, Washington, pp. A250 - A250, presented at Digestive Disease Weeking Meeting/ASGE Postgraduate Course Meeting, DC, Washington, 19 May 2007 - 24 May 2007, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000245927602142&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Williams E; Chaffer C; Oakes SR; Ormandy CJ; Blick T; Thompson E, 2007, 'Mesenchymal to epithetial transition in the establishment of secondary tumours: insights from a bladder carcinoma progression series', in Clinical and Experimental Metastasis, Kluwer Academic Publ, pp. 262 - 262, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000248687200097&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Williams ED; Chaffer CL; Oakes SR; Ormandy CJ; Blick T; Thompson EW, 2006, 'Mesenchymal to epithelial transition in the establishment of secondary tumors: Insights from a bladder carcinoma progression series', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000454606204397&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

ClementLacroix P; Ormandy CJ; Lepescheux L; Goffin V; Bouhard B; Amling M; Binart N; GaillardKelly M; Baron R; Kelly PA, 1997, 'Analysis of bone from prolactin receptor knockout mice: Influence of prolactin in normal murine osteoblasts.', in JOURNAL OF BONE AND MINERAL RESEARCH, BLACKWELL SCIENCE INC, pp. 156 - 156, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997XP62700156&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts

Gallego-Ortega D; Ledger A; Roden D; Cho C; Allerdice SL; Lee HJ; Valdes-Mora F; Lee B; Kaplan W; Salomon R; Piggin C; Rabinovich B; Millar E; Chtanova T; Swarbrick A; Clark S; Ormandy C, 2015, 'The ETS transcription factor ELF5 drives metastasis via angiogenesis and recruitment of Gr-1+ CD11b+ myeloid derived suppressor cells in luminal breast cancer', in Clinical and Experimental Metastasis, Springer Verlag (Germany), Vol. 32, pp. 203 - 203, presented at MRS 15th International biennial congress of the metastasis research society

Nair R; Teo WS; Ye S; McFarland A; Harvey K; Roden D; Junankar S; Baker L; Yang J; Fluke N; Millar E; Mellick A; Naylor M; Ormandy C; Lakhani S; O'Toole S; Swarbrick A, 2015, 'The Inhibitor of Differentiation proteins mediate tumour-initiating properties and metastasis in breast cancer', in CLINICAL & EXPERIMENTAL METASTASIS, SPRINGER, Vol. 32, pp. 224 - 224, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000351601900129&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Byrne FL; Phillips PA; Hansford LM; Fletcher JI; Ormandy CJ; McCarroll JA; Kavallaris M, 2012, 'Stathmin suppression influences ROCK signaling and reduces cell invasion and metastasis in neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-1444

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