By Professor Don Edward Smith

Journal articles

Sasson SC; Zaunders J; Seddiki N; Mcbride K; Koelsch KK; Merlin KM; Smith DE; Cooper DA; Kelleher AD; Bailey MR, 2012, 'Progressive activation of CD127+132- recent thymic emigrants into terminally differentiated CD127-132+ T-cells in HIV-1 infection', PLoS One, 7, pp. e31148, http://dx.doi.org/10.1371/journal.pone.0031148

Smith DE; Chan D; Maruszak H; Jeganathan S, 2011, 'Clinical experience with nevirapine combined with tenofovir plus emtricitabine or lamivudine-containing regimens in HIV-infected subjects', International Journal of STD and AIDS, 22, pp. 228 - 230, http://dx.doi.org/10.1258/ijsa.2010.010258

Jarrin I; Geskus R; Bhaskaran K; Prins M; Perez-Hoyos S; Muga R; Hernández-Aguado I; Meyer L; Porter K; Amo JD; Bucher H; Chêne G; Pillay D; Rosinska M; Sabin C; Touloumi G; del Amo J; Pillay D; Sabin C; Touloumi G; Walker S; Babiker A; Darbyshire J; de Luca A; Fisher M; Goujard C; Muga R; Kaldor J; Kelleher T; Gelgor L; Ramacciotti T; Cooper D; Smith D; Gill J; Bruun Jørgensen L; Nielsen C; Pedersen C; Lutsar I; Dabis F; Thiebaut R; Masquelier B; Costagliola D; Vanhems P; Boufassa F; Hamouda O; Kucherer C; Pantazis N; Hatzakis A; Paraskevis D; Karafoulidou A; Rezza G; Dorrucci M; Longo B; Balotta C; van Asten L; van der Bij A; Coutinho R; Sannes M; Brubakk O; Eskild A; Bruun JN; Camacho R; Smolskaya T; Tor J; de Olalla PG; Caylà J; del Romero J; Belda J; Rickenbach M; Francioli P; Malyuta R; Brettle R; Delpech V; Lattimore S; Murphy G; Parry J; Gill N; Lee C; Johnson A; Phillips A; Babiker A, 2008, 'Gender differences in HIV progression to AIDS and death in industrialized countries: Slower disease progression following HIV seroconversion in women', American Journal of Epidemiology, 168, pp. 532 - 540, http://dx.doi.org/10.1093/aje/kwn179

Begley K; Chan DJ; Jeganathan S; Batterham M; Smith DE, 2008, 'Correlates of unprotected anal intercourse in HIV positive men attending an HIV/AIDS clinic in Sydney.', Curr HIV Res, 6, pp. 579 - 584, http://dx.doi.org/10.2174/157016208786501508

Voirin N; Routy J; Smith DE; Baratin D; Trepo C; Cotte L; Touraine JL; Livrozet J; Cooper DA; Ritter J; Andre P; Vanhems P, 2008, 'Effect of early initiation of highly active antiretroviral therapy on CD4 cell count and HIV-RNA viral load trends within 24 months of the onset of acute retroviral syndrome', HIV Medicine, 9, pp. 440 - 444, http://dx.doi.org/10.1111/j.1468-1293.2008.00576.x

Chan DJ; Mcnally L; Batterham M, 2008, 'Relationship between HIV-RNA load in blood and semen in antiretroviral-naive and experienced men and effect of asymptomatic sexually transmissible infections', Current HIV Research, 6, pp. 138 - 142

Calmy A; Petoumenos K; Lewden C; Law MG; Bocquentin F; Hesse K; Cooper DA; Carr AD; Bonnet F, 2007, 'Combination antiretroviral therapy without a nucleoside reverse transcriptase inhibitor: experience from 334 patients in three cohorts', HIV Medicine, 8, pp. 171 - 180

Smith DE; Gold J, 2007, 'Famciclovir or valaciclovir in the management of herpes simplex and varicella zoster infections: an attitudinal survey of clinician perceptions of differential activity.', Sex Health, 4, pp. 141 - 142, http://dx.doi.org/10.1071/sh06060

Hoen B; Cooper DA; Lampe F; Perrin L; Clumeck N; Phillips AN; Goh L; Lindback S; Sereni D; Gazzard B; Montaner JS; Stellbrink H; Lazzarin A; Ponscarme D; Staszewski S; Mathiesen L; Smith DE; Finlayson R; Weber R; Wegmann L; Janossy G; Kinloch-De Loes S, 2007, 'Predictors of virological outcome and safety in primary HIV type 1-infected patients initiating quadruple antiretroviral therapy: QUEST GW PROB3005.', Clinical Infectious Diseases, 45, pp. 381 - 390

Poynten IM; Smith DE; Cooper DA; Kaldor JM; Grulich AE, 2007, 'The public health impact of widespread availability of nonoccupational postexposure prophylaxis against HIV', HIV Medicine, 8, pp. 374 - 381

Smith D, 2006, 'Editorial: The long-term consequences of antiretroviral therapy', Journal of HIV Therapy, 11, pp. 24 - 25

Jeganathan S; Smith D; Gold J, 2006, 'Early clinical experience with atazanavir in treatment-experienced patients', Sexual Health, 3, pp. 33 - 35, http://dx.doi.org/10.1071/SH05022

Thiébaut R; Jacqmin-Gadda H; Walker AS; Sabin C; Prins M; Del Amo J; Porter K; Dabis F; Chêne G; Beral V; Coutinho R; Darbyshire JH; Gill N; Lee C; Meyer L; Rezza G; Babiker A; Tyrer F; Lawson-Ayayi S; Boufassa F; Hamouda O; Poggensee G; Longo B; Pezzotti P; Touloumi G; Hatzakis A; Karafoulidou A; Katsarou O; Brettle R; del Romero J; van Asten L; van der Bij A; Geskus R; Pedersen C; Hernández Aguado I; Pérez-Hoyos S; Eskild A; Bruun JN; Sannes M; Francioli P; Vanhems P; Egger M; Rickenbach M; Cooper D; Kaldor J; Ramacciotti T; Smith D; Muga R; Tor J; Gill J; Cayla J; Garcia de Olalla P; Day NE; De Angelis D, 2006, 'Determinants of response to first HAART regimen in antiretroviral-naïve patients with an estimated time since HIV seroconversion', HIV Medicine, 7, pp. 1 - 9, http://dx.doi.org/10.1111/j.1468-1293.2005.00332.x

Smith DE; Jeganathan S; Ray J, 2006, 'Atazanavir plasma concentrations vary significantly between patients and correlate with increased serum bilirubin concentrations.', HIV Clin Trials, 7, pp. 34 - 38, http://dx.doi.org/10.1310/0KX0-H9VH-99EE-5D0L

Sasson SC; Zaunders J; Zanetti G; King E; Merlin K; Smith DE; Stanley K; Cooper DA; Kelleher AD, 2006, 'Increased plasma interleukin-7 level correlates with decreased CD127 and increased CD132 extracellular expression on T cell subsets in patients with HIV-1 infection', Journal of Infectious Diseases, 193, pp. 505 - 514

Bloch MT; Smith DE; Quan D; Kaldor JM; Zaunders J; Petoumenos K; Irvine K; Law MG; Grey PA; Finlayson R; Mcfarlane R; Kelleher AD; Carr AD; Cooper DA, 2006, 'The role of hydroxyurea in enhancing the virologic control achieved through structured treatment interruption in primary HIV infection: Final results from a randomized clinical trial (Pulse)', JAIDS: Journal of Acquired Immune Deficiency Syndromes, 42, pp. 192 - 202

Kinloch-De Loes S; Hoen B; Smith DE; Autran B; Lampe FC; Phillips AN; Goh LE; Andersson J; Tsoukas C; Sonnerborg A; Tambussi G; Girard PM; Bloch M; Battegay M; Carter N; El Habib R; Theofan G; Cooper DA; Perrin L, 2005, 'Impact of therapeutic immunization on HIV-1 viremia after discontinuation of antiretroviral therapy initiated during acute infection', Journal of Infectious Diseases, 192, pp. 607 - 617, http://dx.doi.org/10.1086/432002

Smith D, 2005, 'Importance of understanding what is happening with HIV in different body compartments', Journal of HIV therapy, 10, pp. 3 - 4

Petoumenos K; Ringland C, 2005, 'Antiretroviral treatment change among HIV, hepatitis B virus and hepatitis C virus co-infected patients in the Australian HIV Observational Database', HIV Medicine, 6, pp. 155 - 163

Zaunders J; Munier M; Kaufmann D; Ip S; Grey PA; Smith DE; Ramacciotti TP; Quan D; Finlayson RJ; Kaldor JM; Rosenberg E; Walker BD; Cooper DA; Kelleher AD, 2005, 'Early proliferation of CCR5(+) CD38(+++) antigen-specific CD4(+) Th1 effector cells during primary HIV-1 infection', Blood, 106, pp. 1660 - 1667

Hoy JF; Gahan M; Carr AD; Smith DE; Lewin S; Wesselingh S; Cooper DA, 2004, 'Changes in mitochondrial DNA in peripheral blood mononuclear cells from HIV-infected patients with lipoatrophy randomized to receive abacavir', Journal of Infectious Diseases, 190, pp. 688 - 692

Smith DE; Walker BD; Cooper DA; Rosenberg E; Kaldor J, 2004, 'Is antiretroviral treatment of primary HIV infection clinically justified on the basis of current evidence?', AIDS, 18, pp. 709 - 718

Martin A; Smith DE; Carr AD; Hoy JF; Chuah J; Mallal SA; Law MG; Clements MS; Cooper DA, 2004, 'Progression of lipodystrophy (LD) with continued thymidine analogue usage: Long-term follow-up from a randomized clinical trial (the PIILR study)', HIV Clinical Trials, 5, pp. 192 - 200, http://thomasland.metapress.com/content/0gu76x27mmhe5ale/

Martin A; Smith DE; Carr AD; Ringland C; Amin J; Emery S; Hoy JF; Workman C; Doong N; Freund J; Cooper DA, 2004, 'Reversibility of lipoatrophy in HIV-infected patients 2 years after switching from a thymidine analogue to abacavir: the MITOX Extension Study', AIDS, 18, pp. 1029 - 1036, http://www.medscape.com/viewarticle/474870

Smith DE; Hudson J; Martin A; Freund J; Griffiths MR; Kalnins S; Law M; Carr A; Cooper DA; Group and Investigators FTPD, 2003, 'Centralized Assessment of Dual-Energy X-ray Absorptiometry (DEXA) in Multicenter Studies of HIV-Associated Lipodystrophy', HIV Research & Clinical Practice, 4, pp. 45 - 49, http://dx.doi.org/10.1310/hct.2003.4.1.006

Smith DE; Hudson J; Martin A; Freund J; Griffiths MR; Kalnins S; Law MG; Carr AD; Cooper DA, 2003, 'Centralised assessment of dual-energy x-ray absorptiometry (DEXA) in multicenter studies of HIV-associated lipodystrophy', HIV Clinical Trials, 4, pp. 45 - 49

Smith DE; Kaufmann GR; Kahn JO; Hecht FM; Grey PA; Zaunders J; Cunningham PH; Carr AD; Duncombe CJ; Quan D; Petersen A; Cooper DA, 2003, 'Greater reversal of CD4+ cell abnormalities and viral load reduction after initiation of antiretroviral therapy with zidovudine, lamivudine and nelfinavir before complete HIV type 1 seroconversion', AIDS Research and Human Retroviruses, 19, pp. 189 - 199

Miller J; Carr AD; Emery S; Law MG; Mallal SS; Baker D; Smith DG; Kaldor JM; Cooper DA, 2003, 'HIV lipodystrophy: prevalence, severity and correlates of risk in Australia', HIV Medicine, 4, pp. 293 - 301

Lincoln DW; Petoumenos K; Dore GJ, 2003, 'HIV/HBV and HIV/HCV coinfection, and outcomes following highly active antiretroviral therapy', HIV Medicine, 4, pp. 241 - 249

Zaunders J; Moutouh-de Parseval L; Kitada S; Reed JC; Rought S; Genini D; Leoni L; Kelleher AD; Cooper DA; Smith DE; Grey PA; Estaquier J; Little S; Richman DD; Corbeil J, 2003, 'Polyclonal proliferation and apoptosis of CCR5+ T Lymphocytes during primary human immunodeficiency virus type 1 infection: regulation by interleukin (IL)-2, IL-15, and Bcl-2', Journal of Infectious Diseases, 187, pp. 1735 - 1735

Smith DG; Carr AD; Law MG; Martin A; Hoy JF; Hudson J; Cooper DA, 2003, 'Thymidine analogue withdrawal for patients on protease sparing therapy improves lipoatrophy but compromises antivrial control:the PIILR extension study', AIDS, 16, pp. 2489 - 2491, http://journals.lww.com/aidsonline/fulltext/2002/12060/thymidine_analogue_withdrawal_for_lipoatrophic.20.aspx

Carr AD; Workman C; Smith DE; Hoy JF; Hudson J; Doong N; Martin A; Amin J; Freund J; Law MG; Cooper DA, 2002, 'Abacavir substitution for nucleoside analogs in patients with HIV lipoatrophy', JAMA - Journal of the American Medical Association, 288, pp. 207 - 215

Appay V; Zaunders J; Papagno L; Sutton J; Jaramillo AB; Waters A; Eastbrook P; Grey PA; Smith DE; Mcmichael AJ; Cooper DA; Rowland-Jones SL; Kelleher AD, 2002, 'Characterization of CD4(+) CTLs ex vivo', Journal of Immunology, 168, pp. 5954 - 5958

Lewin S; Ribeiro RM; Kaufmann GR; Smith DE; Zaunders J; Law MG; Solomon A; Cameron P; Cooper DA; Perelson AS, 2002, 'Dynamics of T cells and TCR excision circles differ after treatment of acute and chronic HIV infection', Journal of Immunology, 169, pp. 4657 - 4666

McDonald AM; Dore GJ; Grulich AE; Law MG; Prestage G; Smith DE, 2002, 'Epidemiological and social research finds at the 14th International AIDS Conference', Australian HIV Surveillance Report, 18, pp. 1 - 8

Carr AD; Workman C; Smith DE; Hoy JF; Doong N; Amin J; Law MG; Cooper DA, 2002, 'For the MITOX investigators: Abacavir substitution for nucleoside analogs in patients with HIV lipoatrophy: a randomized trial', Journal of the American Medical Association, 288, pp. 207 - 215

Smith DE, 2002, 'Immune responses against HIV: what we want and what we get', Journal of Hiv Therapy, 7, pp. 27 - 29

Kaufmann GR; Smith DE; Bucher HC; Phanuphak P; Sendi PP; Mdibbe EK; Cooper DA; Battegay M, 2002, 'Potential benefit and limitations of a broad access to potent antiretroviral therapy in developing countries', Expert Opinion on Investigational Drugs, 11, pp. 1303 - 1313

Baker D; Law MG; Petoumenos K; Smith DE; Anderson JA; Roth N; Mallal SA, 2002, 'Rates of combination antiretroviral treatment change in Australia, 1997-2000', HIV Medicine, 3, pp. 28 - 36

Kaufmann GR; Bloch MT; Finlayson RJ; Zaunders J; Smith DE; Cooper DA, 2002, 'The extent of HIV-1-related immunodeficiency and age predict the long-term CD4 T lymphocyte response to potent antiretroviral therapy', AIDS, 16, pp. 359 - 367

Smith DE; Carr AD; Law MG; Hudson J; Hoy JF; Cooper DA, 2002, 'Thymidine analogue withdrawal for lipoatrophic patients on protease-sparing therapy improves lipoatrophy but compromises antiviral control: the PIILR extension study', AIDS, 16, pp. 2489 - 2491

Grulich AE; Zheng W; Smith DE, 2002, 'Use of non-occupational post-exposure prophylaxis in Australia', Australian HIV Surveillance Report, 18, pp. 1 - 6

Smith DE; Hales GP; Roth N; Law MG; Ray J; Druett J; Mitchell J; Mills G; Doong N; Franklin R, 2001, 'A randomized trial of nelfinavir, ritonavir, or delavirdine in combination with saquinavir¿SGC and stavudine in treatment¿experienced HIV-1 infected patients.', HIV Clinical Trials, 2, pp. 97 - 107

Smith DE; Bell J; Johnson MA; Youle M; Gazzard B; Tchamouroff S; Frechette G; Schlech W; Miller S; Spencer D; Seifert W; Peeters M; De Beule K, 2001, 'A randomized, double-blind, placebo-controlled study of itraconazole capsules for the prevention of deep fungal infections in immunodeficient patients with HIV infection.', HIV Medicine, 2, pp. 78 - 83

Middleton T; Smith DE; Larder BA; Law MG; Birch C, 2001, 'Baseline antiretroviral drug susceptibility influences treatment response in patients receiving saquinavir-enhancing therapy.', HIV Clinical Trials, 2, pp. 445 - 452

Carr AD; Hudson J; Chuah J; Law MG; Mallal SA; Hoy JF; Doong N; French MA; Smith DE; Cooper DA, 2001, 'HIV protease inhibitor substitution in patients with lipodystrophy: a randomized, controlled, open-label, multicentre study', AIDS, 15, pp. 1811 - 1822

Zaunders J; Kaufmann GR; Cunningham PH; Smith DE; Grey PA; Suzuki K; Carr AD; Goh L; Cooper DA, 2001, 'Increased turnover of CCR5+ and redistribution of CCR5- CD4 T lymphocytes during primary human immunodeficiency virus type 1 infection.', Journal of Infectious Diseases, 183, pp. 736 - 743

Kaufmann GR; Zaunders J; Murray JM; Kelleher AD; Lewin S; Solomon A; Smith DE; Cooper DA, 2001, 'Relative significance of different pathways of immune reconstitution in HIV type 1 infection as estimated by mathematical modelling.', AIDS Research and Human Retroviruses, 17, pp. 147 - 159

Hales GP; Beveridge A; Smith DE, 2001, 'The conflicting roles of clinicians versus investigators in HIV randomised clinical trials', Culture, Health and Sexuality, 3, pp. 67 - 69

Smith DE; Gow I; Colebunders R; Weller IV; Tchamouroff S; Weber J; Boag F; Hales GP; Adams S; Patou G; Cooper DA, 2001, 'Therapeutic vaccination (p24-VLP) of patients with advanced HIV-1 infection in the pre-HAART era does not alter CD4 cell decline.', HIV Medicine, 2, pp. 272 - 275

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