By Professor Kyle Lee Hoehn

Journal articles

Patel SA; Hoehn KL; Lawrence RT; Sawbridge L; Talbot NA; Tomsig JL; Turner N; Cooney GJ; Whitehead JP; Kraegen E; Cleasby ME, 2012, 'Overexpression of the adiponectin receptor AdipoR1 in rat skeletal muscle amplifies local insulin sensitivity', Endocrinology, 153, pp. 5231 - 5246, http://dx.doi.org/10.1210/en.2012-1368

Hoehn KL; Turner N; Cooney GJ; James DE, 2012, 'Phenotypic discrepancies in acetyl-CoA carboxylase 2-deficient mice', The Journal of Biological Chemistry, 287, pp. 15801, http://dx.doi.org/10.1074/jbc.O112.356915

Park D; Han CZ; Elliott MR; Kinchen JM; Trampont PC; Das S; Collins S; Lysiak JJ; Hoehn KL; Ravichandran KS, 2011, 'Continued clearance of apoptotic cells critically depends on the phagocyte Ucp2 protein', Nature, 477, pp. 220 - 224, http://dx.doi.org/10.1038/nature10340

Murrow BA; Hoehn KL, 2010, 'Mitochondrial regulation of insulin action', International Journal of Biochemistry and Cell Biology, 42, pp. 1936 - 1939, http://dx.doi.org/10.1016/j.biocel.2010.08.020

Akhtar YN; Lira VA; Zhang M; Okutsu M; Hoehn KL; Yan Z, 2010, 'Genetic ablation of cyclophilin D, a component of the mitochondrial permeability transition pore, improves insulin sensitivity in high-fat fed mice', FASEB JOURNAL, 24, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208675507150&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Hoehn KL; Holland WL; Knotts TA; Summers SA, 2010, 'The etiology of obesity-induced insulin resistance', , pp. 205 - 238

Hoehn KL; Turner N; Swarbrick MM; Wilks D; Preston E; Phua Y; Joshi H; Furler SM; Larance M; Hegarty BD; Leslie SJ; Pickford R; Hoy AJ; Kraegen EW; James DE; Cooney GJ; Hegarty , 2010, 'Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity', Cell Metabolism, 11, pp. 70 - 76, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=20074529

Larance M; Rowland AF; Hoehn KL; Humphreys D; Preiss T; Guilhaus M; James DE, 2010, 'Global phosphoproteomics identifies a major role for AKT and 14-3-3 in regulating EDC3', Molecular and Cellular Proteomics, 9, pp. 682 - 694, http://dx.doi.org/10.1074/mcp.M900435-MCP200

Richards AA; Colgrave ML; Zhang J; Webster J; Simpson F; Preston E; Wilks D; Hoehn KL; Stephenson M; Macdonald GAM; Prins J; Cooney GJ; Xu A; Whitehead JR, 2010, 'Sialic acid modification of adiponectin is not required for multimerization or secretion but determines half-life in circulation', Molecular Endocrinology, 24, pp. 229 - 239, http://dx.doi.org/10.1210/me.2009-0133

Hoehn KL; Holland WL; Knotts TA; Summers SA, 2009, 'The etiology of obesity-induced insulin resistance', , pp. 99 - 132

Hoehn K; Salmon A; Hohnen-Behrens C; Turner N; Hoy A; Maghzal G; Stocker R; Van remmen H; Kraegen E; Cooney GJ; Richardson A; James DE, 2009, 'Insulin resistance is a cellular antioxidant defense mechanism', Proceedings of the National Academy of Sciences of the United States of America, 106, pp. 17787 - 17792, http://www.pnas.org/content/106/42/17787.long

Crowe SM; Wu LE; Economou C; Turpin S; Matzaris M; Hoehn KL; Hevener A; James DE; Duh E; Watt M, 2009, 'Pigment Epithelium-Derived Factor Contributes to Insulin Resistance in Obesity', Cell Metabolism, 10, pp. 40 - 47

Yip M; Ramm G; Larance MC; Hoehn K; Wagner M; Guilhaus M; James DE, 2008, 'CaMKII-Mediated Phosphorylation of the Myosin Motor Myolc Is Required for Insulin-Stimulated GLUT4 Translocation in Adipocytes', Cell Metabolism, 8, pp. 384 - 398

Hoehn K; Hohnen-Behrens C; Cederberg A; Wu LE; Turner N; Yuasa T; Ebina Y; James DE, 2008, 'IRS1-independent defects define major nodes of insulin resistance', Cell Metabolism, 7, pp. 421 - 433, http://dx.doi.org/10.1016/j.cmet.2008.04.005

Holland WL; Knotts TA; Chavez JA; Wang LP; Hoehn KL; Summers SA, 2007, 'Lipid Mediators of Insulin Resistance', Nutrition Reviews, 65, http://dx.doi.org/10.1111/j.1753-4887.2007.tb00327.x

Holland WL; Knotts TA; Chavez JA; Wang L-P; Hoehn KL; Summers SA, 2007, 'Lipid mediators of insulin resistance', NUTRITION REVIEWS, 65, pp. S39 - S46, http://dx.doi.org/10.1301/nr.2007.jun.S39-S46

Holland WL; Knotts TA; Chavez JA; Wang LP; Hoehn KL; Summers SA, 2007, 'Lipid mediators of insulin resistance.', Nutrition reviews, 65

Holland WL; Brozinick JT; Wang LP; Hawkins ED; Sargent KM; Liu Y; Narra K; Hoehn KL; Knotts TA; Siesky A; Nelson DH; Karathanasis SK; Fontenot GK; Birnbaum MJ; Summers SA, 2007, 'Inhibition of Ceramide Synthesis Ameliorates Glucocorticoid-, Saturated-Fat-, and Obesity-Induced Insulin Resistance', Cell Metabolism, 5, pp. 167 - 179, http://dx.doi.org/10.1016/j.cmet.2007.01.002

Turner N; Bruce CR; Beale S; Hoehn K; So T; Rolph MS; Cooney GJ, 2007, 'Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle - Evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents', Diabetes, 56, pp. 2085 - 2092

Cress KE; Hoehn KL; Florant GL, 2006, 'The hunger switch', The FASEB Journal, 20, http://dx.doi.org/10.1096/fasebj.20.4.a177-a

Stratford S; Hoehn KL; Liu F; Summers SA, 2004, 'Regulation of insulin action by ceramide: Dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B', Journal of Biological Chemistry, 279, pp. 36608 - 36615, http://dx.doi.org/10.1074/jbc.M406499200

Hoehn KL; Hudachek SF; Summers SA; Florant GL, 2004, 'Seasonal, tissue-specific regulation of Akt/protein kinase B and glycogen synthase in hibernators', AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 286, pp. R498 - R504, http://dx.doi.org/10.1152/ajpregu.00509.2003

Hoehn KL; Hudachek SF; Summers SA; Florant GL, 2004, 'Seasonal, tissue-specific regulation of Akt/protein kinase B and glycogen synthase in hibernators', American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 286, http://dx.doi.org/10.1152/ajpregu.00509.2003

Hoehn KL; Summers SA, 2003, 'Assaying AKT/protein kinase B activity.', Methods in molecular medicine, 83, pp. 137 - 144, http://dx.doi.org/10.1385/1-59259-377-1:137

Conference Papers

Saur SJ; Maerklin M; Poljak A; Ganser M; James DE; Hoehn K; Kanz L; Kopp H-G; Mueller MR, 2014, 'C-CBL Is a Critical Negative Regulator of Megakaryopoesis', in BLOOD, AMER SOC HEMATOLOGY, CA, San Francisco, presented at 56th Annual Meeting of the American-Society-of-Hematology, CA, San Francisco, 06 December 2014 - 09 December 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000349243500072&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts

Perera C; Hossain MJ; Mekapogu AR; Hosen SMZ; Rajan P; Xu Z; Greenfield J; Hoehn K; Horadagoda N; Chari S; Pirola R; Wilson J; Apte MV, 2022, 'PANCREATIC CANCER-RELATED DIABETES: A HIGH FRUCTOSE DIET FED TO TRANSGENIC, KRAS(LSL-G12D/+); PDXCRE/+ (KC) MICE, IS ASSOCIATED WITH PANCREATIC STELLATE CELL ACTIVATION AND ACCELERATED CANCER PROGRESSION', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, CA, San Diego, Vol. 162, pp. S562 - S563, presented at Digestive Disease Week (DDW), CA, San Diego, 21 May 2022 - 24 May 2022, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000826446202162&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Yeudall S; Upchurch C; Seegren P; Pavelec C; Desai B; Hoehn K; Leitinger N, 2022, 'An Unexpected Role for Acetyl Coenzyme A Carboxylase in Metabolic Control of the Macrophage Acute Inflammatory Response', in Free Radical Biology and Medicine, Elsevier BV, Vol. 180, pp. s88 - s88, http://dx.doi.org/10.1016/j.freeradbiomed.2021.12.269

Cantley J; Whitworth PT; Davenport A; Hoehn KL; James DE; Biden TJ, 2013, 'Acetyl-CoA carboxylase 1 is a critical regulator of beta cell mass', in DIABETOLOGIA, SPRINGER, Barcelona, SPAIN, Vol. 56, pp. S74 - S74, presented at 49th Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Barcelona, SPAIN, 23 September 2013 - 27 September 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000329196900166&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Preprints

Byrne F; Olzomer E; Lolies N; Hoehn KL; Wegner M-S, 2022, Update on Glycosphingolipids Abundance in Hepatocellular Carcinoma, http://dx.doi.org/10.20944/preprints202203.0309.v1

Wegner M-S; Schömel N; Olzomer EM; Trautmann S; Olesch C; Byrne FL; Brüne B; Gurke R; Ferreirós N; Weigert A; Geisslinger G; Hoehn KL, 2021, Increased glucosylceramide production leads to decreased cell energy metabolism and lowered tumor marker expression in non-cancerous liver cells, http://dx.doi.org/10.21203/rs.3.rs-454533/v1

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