By Professor Murray David Norris

Journal articles

Yu DMT; Huynh T; Truong AM; Haber M; Norris MD, 2015, 'ABC Transporters and Neuroblastoma', , 125, pp. 139 - 170, http://dx.doi.org/10.1016/bs.acr.2014.10.005

Milne E; Greenop KR; Scott RJ; Haber M; Norris MD; Attia J; Jamieson SE; Miller M; Bower C; Bailey HD; Dawson S; McCowage GB; De Klerk NH; Van Bockxmeer FM; Armstrong BK, 2015, 'Folate pathway gene polymorphisms, maternal folic acid use, and risk of childhood acute lymphoblastic leukemia', Cancer Epidemiology Biomarkers and Prevention, 24, pp. 48 - 56, http://dx.doi.org/10.1158/1055-9965.EPI-14-0680

Lau DT; Flemming CL; Gherardi S; Perini G; Oberthuer A; Fischer M; Juraeva D; Brors B; Xue C; Norris MD; Marshall GM; Haber M; Fletcher JI; Ashton LJ, 2015, 'MYCN amplification confers enhanced folate dependence and methotrexate sensitivity in neuroblastoma', Oncotarget, 6, pp. 15510 - 15523, http://dx.doi.org/10.18632/oncotarget.3732

Dietrich PA; Yang C; Leung HHL; Lynch JR; Gonzales E; Liu B; Haber M; Norris MD; Wang J; Wang JY; Gonzales-Aloy E, 2014, 'GPR84 sustains aberrant β-catenin signaling in leukemic stem cells for maintenance of MLL leukemogenesis', Blood, 124, pp. 3284 - 3294, http://dx.doi.org/10.1182/blood-2013-10-532523

Cheung L; Flemming CL; Watt F; Masada N; Yu DMT; Huynh T; Conseil G; Tivnan A; Polinsky A; Gudkov AV; Munoz MA; Vishvanath A; Cooper DMF; Henderson MJ; Cole SPC; Fletcher JI; Haber M; Norris MD, 2014, 'High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4).', Biochem Pharmacol, 91, pp. 97 - 108, http://dx.doi.org/10.1016/j.bcp.2014.05.023

Hedditch EL; Gao B; Russell AJ; Lu Y; Emmanuel C; Beesley J; Johnatty SE; Chen X; Harnett P; George J; Williams RT; Flemming C; Lambrechts D; Despierre E; Lambrechts S; Vergote I; Karlan B; Lester J; Orsulic S; Walsh C; Fasching P; Beckmann MW; Ekici AB; Hein A; Matsuo K; Hosono S; Nakanishi T; Yatabe Y; Pejovic T; Bean Y; Heitz F; Harter P; Du Bois A; Schwaab I; Hogdall E; Kjaer SK; Jensen A; Hogdall C; Lundvall L; Engelholm SA; Brown B; Flanagan J; Metcalf MD; Siddiqui N; Sellers T; Fridley B; Cunningham J; Schildkraut J; Iversen E; Weber RP; Berchuck A; Goode E; Bowtell DD; Chenevix-Trench G; Defazio A; Norris MD; Macgregor S; Haber M; Henderson MJ, 2014, 'ABCA transporter gene expression and poor outcome in epithelial ovarian cancer', Journal of the National Cancer Institute, 106, http://dx.doi.org/10.1093/jnci/dju149

Tee AE; Ling D; Nelson C; Atmadibrata B; Dinger ME; Xu N; Mizukami T; Liu PY; Liu B; Cheung B; Pasquier E; Haber M; Norris MD; Suzuki T; Marshall GM; Liu T, 2014, 'The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1.', Oncotarget, 5, pp. 1793 - 1804, http://dx.doi.org/10.18632/oncotarget.1785

Kim PY; Tan O; Diakiw SM; Carter D; Sekerye EO; Wasinger VC; Liu T; Kavallaris M; Norris MD; Haber M; Chesler L; Dolnikov A; Trahair TN; Cheung NK; Marshall GM; Cheung BB, 2014, 'Identification of plasma Complement C3 as a potential biomarker for neuroblastoma using a quantitative proteomic approach', Journal of Proteomics, 96, pp. 1 - 12, http://dx.doi.org/10.1016/j.jprot.2013.10.032

Dorstyn L; Puccini J; Nikolic A; Shalini S; Wilson CH; Norris MD; Haber M; Kumar S, 2014, 'An unexpected role for caspase-2 in neuroblastoma', Cell Death and Disease, 5, pp. e1383 - e1383, http://dx.doi.org/10.1038/cddis.2014.342

Shahbazi J; Scarlett CJ; Norris MD; Liu B; Haber M; Tee AE; Carrier A; Biankin AV; London WB; Marshall GM; Lock RB; Liu T, 2014, 'Histone Deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1', Oncotarget, 5, pp. 4257 - 4268, http://dx.doi.org/10.18632/oncotarget.1991

Saletta F; Wadham C; Ziegler DS; Marshall GM; Haber M; McCowage G; Norris MD; Byrne JA, 2014, 'Molecular profiling of childhood cancer: Biomarkers and novel therapies', Bba Clinical, 1, pp. 59 - 77, http://dx.doi.org/10.1016/j.bbacli.2014.06.003

Saletta F; Wadham C; Byrne J; Ziegler D; McCowage G; Haber M; Marshall G; Norris M, 2014, '421 Molecular profiling for factors predicting sensitivity or resistance to therapy in relapsed child cancer', European Journal of Cancer, 50, pp. 135, http://dx.doi.org/10.1016/s0959-8049(14)70547-7

Norris MD, 2014, 'Neuroblastoma: molecular targets and novel therapies', Pathology, 46, pp. s36, http://dx.doi.org/10.1097/01.pat.0000454208.74479.75

Heong V; Topp M; Rutkowski R; Ananda S; Wong S; Swisher E; Lindeman G; Haber M; Norris MD; Haluska P; Wakefield M; Bowtell D; Scott CL; Lindeman G, 2014, 'OP0024 Use of novel patient-derived xenografts and molecular subtyping to improve precision medicine in high-grade serous ovarian cancer', European Journal of Cancer, 50, pp. e9, http://dx.doi.org/10.1016/j.ejca.2014.03.042

Gao B; Russell A; Beesley J; Chen XQ; Healey S; Henderson M; Wong M; Emmanuel C; Galletta L; Johnatty SE; Bowtell D; Australian Ovarian Cancer Study Group ; Haber M; Norris M; Harnett P; Chenevix-Trench G; Balleine RL; deFazio A, 2014, 'Paclitaxel sensitivity in relation to ABCB1 expression, efflux and single nucleotide polymorphisms in ovarian cancer.', Scientific reports, 4, pp. 4669, http://dx.doi.org/10.1038/srep04669

Dietrich PA; Norris MD; Wang JY, 2013, 'GPR84, a Proinflammatory Receptor, Sustains Wnt/β-Catenin Signaling In Leukemic Stem Cells For Maintenance Of MLL-AF9-Induced Leukemogenesis', Blood, 122, pp. 3781, http://dx.doi.org/10.1182/blood.v122.21.3781.3781

Karsa M; Dalla Pozza L; Venn NC; Law T; Shi R; Giles JE; Bahar AY; Cross S; Catchpoole D; Haber M; Marshall GM; Norris MD; Sutton R, 2013, 'Improving the Identification of High Risk Precursor B Acute Lymphoblastic Leukemia Patients with Earlier Quantification of Minimal Residual Disease', PLoS ONE, 8, http://dx.doi.org/10.1371/journal.pone.0076455

Calao M; Sekyere EO; Cui HJ; Cheung BB; Thomas WD; Keating J; Chen JB; Raif A; Jankowski K; Davies NP; Bekkum MV; Chen B; Tan O; Ellis T; Norris MD; Haber M; Kim ES; Shohet JM; Trahair TN; Liu T; Wainwright BJ; Ding HF; Marshall GM, 2013, 'Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation.', Oncogene, 32, pp. 3616 - 3626, http://dx.doi.org/10.1038/onc.2012.368

Marshall GM; Dalla Pozza L; Sutton R; Ng A; De Groot-Kruseman HA; Van Der Velden VH; Venn NC; Van Den Berg H; De Bont ESJM; Maarten Egeler R; Hoogerbrugge PM; Kaspers GJL; Bierings MB; Van Der Schoot E; Van Dongen J; Law T; Cross S; Mueller H; De Haas V; Haber M; Révész T; Alvaro F; Suppiah R; Norris MD; Pieters R, 2013, 'High-risk childhood acute lymphoblastic leukemia in first remission treated with novel intensive chemotherapy and allogeneic transplantation', Leukemia, 27, pp. 1497 - 1503, http://dx.doi.org/10.1038/leu.2013.44

Pasquier E; Street J; Pouchy C; Carre M; Gifford AJ; Murray J; Norris MD; Trahair T; Andre N; Kavallaris M, 2013, 'B-blockers increase response to chemotherapy via direct antitumour and anti-angiogenic mechanisms in neuroblastoma', British Journal of Cancer, 108, pp. 2485 - 2494, http://dx.doi.org/10.1038/bjc.2013.205

Johnatty SE; Beesley J; Gao B; Chen X; Lu Y; Law MH; Henderson MJ; Russell AJ; Hedditch EL; Emmanuel C; Fereday S; Webb PM; Goode EL; Vierkant RA; Fridley BL; Cunningham JM; Fasching PA; Beckmann MW; Ekici AB; Hogdall E; Kjaer SK; Jensen A; Hogdall C; Brown R; Paul J; Lambrechts S; Despierre E; Vergote I; Lester J; Karlan BY; Heitz F; Du Bois A; Harter P; Schwaab I; Bean Y; Pejovic T; Levine DA; Goodman MT; Camey ME; Thompson PJ; Lurie G; Shildkraut J; Berchuck A; Terry KL; Cramer DW; Norris MD; Haber M; MacGregor S; DeFazio A; Chenevix-Trench G, 2013, 'ABCB1 (MDR1) polymorphisms and ovarian cancer progression and survival: A comprehensive analysis from the Ovarian Cancer Association Consortium and the Cancer Genome Atlas', Gynecologic Oncology, 131, pp. 8 - 14, http://dx.doi.org/10.1016/j.ygyno.2013.07.107

Burkhart CA; Haber M; Norris MD; Gudkov AV; Nikiforov MA, 2013, 'Cell-based methods for the identification of Myc-inhibitory small molecules', Methods in Molecular Biology, 1012, pp. 255 - 264, http://dx.doi.org/10.1007/978-1-62703-429-6_18

Malyukova A; Brown S; Papa R; O'Brien R; Giles J; Trahair TN; Dalla Pozza L; Sutton R; Liu T; Haber M; Norris MD; Lock RB; Sangfelt O; Marshall GM, 2013, 'FBXW7 regulates glucocorticoid response in T-cell acute lymphoblastic leukaemia by targeting the glucocorticoid receptor for degradation', Leukemia, 27, pp. 1053 - 1062, http://dx.doi.org/10.1038/leu.2012.361

Liu PY; Xu N; Malyukova A; Scarlett CJ; Sun YT; Zhang XD; Ling D; Su S-P; Nelson C; Chang DK; Koach J; Tee AE; Haber M; Norris MD; Toon C; Rooman I; Xue C; Cheung BB; Kumar S; Marshall GM; Biankin AV; Liu T, 2013, 'The histone deacetylase SIRT2 stabilizes Myc oncoproteins.', Cell Death Differ, 20, pp. 503 - 514, http://dx.doi.org/10.1038/cdd.2012.147

Kim PY; Rahmanto AS; Tan O; Norris MD; Haber M; Marshall GM; Cheung BB, 2013, 'TRIM16 overexpression induces apoptosis through activation of caspase-2 in cancer cells.', Apoptosis, 18, pp. 639 - 651, http://dx.doi.org/10.1007/s10495-013-0813-y

Huynh T; Norris MD; Haber M; Henderson MJ, 2012, 'ABCC4/MRP4: a MYCN-regulated transporter and potential therapeutic target in neuroblastoma', FRONTIERS IN ONCOLOGY, 2, http://dx.doi.org/10.3389/fonc.2012.00178

Wang JY; Sprod O; Haber M; Norris MD, 2012, 'Epigenetic Elimination of Mixed-Lineage Leukemia Leukemic Stem Cells by a Potent Small Molecule PRC2 Inhibitor.', Blood, 120, pp. 2456, http://dx.doi.org/10.1182/blood.v120.21.2456.2456

Lau DT; Hesson LB; Norris MD; Marshall G; Haber M; Ashton LJ, 2012, 'Abstract 68: Beyond GWAS: The prognostic significance of promoter DNA methylation in patients with neuroblastoma.', Cancer Epidemiology Biomarkers & Prevention, 21, pp. 68 - 68, http://dx.doi.org/10.1158/1055-9965.gwas-68

Lau DT; Hesson LB; Norris MD; Marshall GM; Haber M; Ashton LJ, 2012, 'Prognostic significance of promoter DNA methylation in patients with childhood neuroblastoma.', Clin Cancer Res, 18, pp. 5690 - 5700, http://dx.doi.org/10.1158/1078-0432.CCR-12-0294

Lau DT; Hesson LB; Norris MD; Haber M; Marshall GM; Ashton LJ, 2012, 'Abstract 1425: Prognostic significance of promoter DNA methylation in patients with neuroblastoma', Cancer Research, 72, pp. 1425 - 1425, http://dx.doi.org/10.1158/1538-7445.am2012-1425

Fletcher JI; Gherardi S; Murray J; Burkhart CA; Russell A; Valli E; Smith J; Oberthuer A; Ashton LJ; London WB; Marshall GM; Norris MD; Perini G; Haber M, 2012, 'N-Myc regulates expression of the detoxifying enzyme glutathione transferase GSTP1, a marker of poor outcome in neuroblastoma.', Cancer Res, 72, pp. 845 - 853, http://dx.doi.org/10.1158/0008-5472.CAN-11-1885

Venn NC; van der Velden VHJ; de Bie M; Waanders E; Giles JE; Law T; Kuiper RP; de Haas V; Mullighan CG; Haber M; Marshall GM; Md N; van Dongen JJM; Sutton R, 2012, 'Highly sensitive MRD tests for ALL based on the IKZF1 Δ3-6 microdeletion.', Leukemia, 26, pp. 1414 - 1416, http://dx.doi.org/10.1038/leu.2011.348

Gamble LD; Hogarty MD; Liu X; Ziegler DS; Marshall G; Norris MD; Haber M, 2012, 'Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma.', Front Oncol, 2, pp. 162, http://dx.doi.org/10.3389/fonc.2012.00162

Cheung BB; Koach J; Tan O; Kim P; Bell JL; D'andreti C; Sutton S; Malyukova A; Sekyere E; Norris M; Haber M; Kavallaris M; Cunningham AM; Proby C; Leigh I; Wilmott JS; Cooper CL; Halliday GM; Scolyer RA; Marshall GM, 2012, 'The retinoid signalling molecule, TRIM16, is repressed during squamous cell carcinoma skin carcinogenesis in vivo and reduces skin cancer cell migration in vitro.', J Pathol, 226, pp. 451 - 462, http://dx.doi.org/10.1002/path.2986

Henderson MJ; Haber M; Porro A; Munoz MA; Iraci N; Xue C; Murray J; Flemming CL; Smith J; Fletcher JI; Gherardi S; Kwek C-K; Russell AJ; Valli E; London WB; Buxton AB; Ashton LJ; Sartorelli AC; Cohn SL; Schwab M; Marshall GM; Perini G; Norris MD, 2011, 'ABCC multidrug transporters in childhood neuroblastoma: clinical and biological effects independent of cytotoxic drug efflux.', J Natl Cancer Inst, 103, pp. 1236 - 1251, http://dx.doi.org/10.1093/jnci/djr256

Pajic M; Murray J; Marshall GM; Cole SPC; Norris MD; Haber M, 2011, 'ABCC1 G2012T single nucleotide polymorphism is associated with patient outcome in primary neuroblastoma and altered stability of the ABCC1 gene transcript.', Pharmacogenet Genomics, 21, pp. 270 - 279, http://dx.doi.org/10.1097/FPC.0b013e328343dd5f

Porro A; Iraci N; Soverini S; Diolaiti D; Gherardi S; Terragna C; Durante S; Valli E; Kalebic T; Bernardoni R; Perrod C; Haber M; Norris MD; Baccarani M; Martinelli G; Perini G, 2011, 'c-MYC Oncoprotein Dictates Transcriptional Profiles of ATP-Binding Cassette Transporter Genes in Chronic Myelogenous Leukemia CD34(+) Hematopoietic Progenitor Cells', Molecular Cancer Research, 9, pp. 1054 - 1066, http://dx.doi.org/10.1158/1541-7786.MCR-10-0510

Lau DT; Norris MD; Marshall GM; Haber M; Ashton LJ, 2011, 'HLA-G polymorphisms, genetic susceptibility, and clinical outcome in childhood neuroblastoma.', Tissue Antigens, 78, pp. 421 - 427, http://dx.doi.org/10.1111/j.1399-0039.2011.01781.x

Marshall GM; Liu PY; Gherardi S; Scarlett CJ; Bedalov A; Xu N; Iraci N; Valli E; Ling D; Thomas W; van Bekkum M; Sekyere E; Jankowski K; Trahair T; Mackenzie KL; Haber M; Norris MD; Biankin AV; Perini G; Liu T, 2011, 'SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability.', PLoS Genet, 7, pp. e1002135, http://dx.doi.org/10.1371/journal.pgen.1002135

Marshall GM; Bell JL; Koach J; Tan O; Kim P; Malyukova A; Thomas W; Sekyere EO; Liu T; Cunningham AM; Tobias V; Norris MD; Haber M; Kavallaris M; Cheung BB, 2010, 'TRIM16 acts as a tumour suppressor by inhibitory effects on cytoplasmic vimentin and nuclear E2F1 in neuroblastoma cells.', Oncogene, 29, pp. 6172 - 6183, http://dx.doi.org/10.1038/onc.2010.340

Marshall GM; Gherardi S; Xu N; Neiron Z; Trahair T; Scarlett CJ; Chang DK; Liu PY; Jankowski K; Iraci N; Haber M; Norris MD; Keating J; Sekyere E; Jonquieres G; Stossi F; Katzenellenbogen BS; Biankin AV; Perini G; Liu T, 2010, 'Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects.', Oncogene, 29, pp. 5957 - 5968, http://dx.doi.org/10.1038/onc.2010.332

Swarbrick A; Woods SL; Shaw A; Balakrishnan A; Phua Y; Nguyen A; Chanthery Y; Lim L; Ashton LJ; Judson RL; Huskey N; Blelloch R; Haber M; Norris MD; Lengyel P; Hackett CS; Preiss T; Chetcuti A; Sullivan CS; Marcusson EG; Weiss W; L'Etoile N; Goga A, 2010, 'MiR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma', Nature Medicine, 16, pp. 1134 - 1140, http://dx.doi.org/10.1038/nm.2227

Porro A; Haber M; Diolaiti D; Iraci N; Henderson M; Gherardi S; Valli E; Munoz MA; Xue C; Flemming C; Schwab M; Wong JH; Marshall GM; Della Valle G; Norris MD; Perini G, 2010, 'Direct and coordinate regulation of ATP-binding cassette transporter genes by Myc factors generates specific transcription signatures that significantly affect the chemoresistance phenotype of cancer cells.', J Biol Chem, 285, pp. 19532 - 19543, http://dx.doi.org/10.1074/jbc.M109.078584

Tee AEL; Marshall GM; Liu PY; Xu N; Haber M; Norris MD; Iismaa SE; Liu T, 2010, 'Opposing effects of two tissue transglutaminase protein isoforms in neuroblastoma cell differentiation.', J Biol Chem, 285, pp. 3561 - 3567, http://dx.doi.org/10.1074/jbc.M109.053041

Fletcher JI; Haber M; Henderson M; Norris MD, 2010, 'ABC transporters in cancer: more than just drug efflux pumps', Nature Reviews Cancer, 10, pp. 147 - 156, http://dx.doi.org/10.1038/nrc2789

Bhadri V; McGregor MR; Venn NC; Hackenberg N; Russell SJ; Norris MD; Haber M; Sutton R; Marshall GM, 2010, 'Isolated testicular relapse after allo-SCT in boys with ALL: outcome without second transplant', Bone Marrow Transplantation, 45, pp. 397 - 399, http://dx.doi.org/10.1038/bmt.2009.138

Milne E; Royle JA; Miller M; Bower C; de klerk NH; Bailey HD; Van brockxmeer F; Attia J; Scott RJ; Norris MD; Haber M; Thompson JR; Fritschi L; Marshall GM; Armstrong B, 2010, 'Maternal folate and other vitamin supplementation during pregnancy and risk of acute lymphoblastic leukemia in the offspring', International Journal of Cancer, 126, pp. 2690 - 2699, http://dx.doi.org/10.1002/ijc.24969

Evageliou N; Vu A; Liu X; Barr R; Hayes C; Norris M; Marshall G; Haber M; Gilmour S; Hogarty M, 2009, 'DUAL TARGETING OF AMD1 AND ODC1 POTENTLY INHIBITS NEUROBLASTOMA INITIATION IN THE TH-MYCN MOUSE MODEL', PEDIATRIC BLOOD & CANCER, 52, pp. 731 - 731, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000264515600128&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Bohlken A; Cheung B; Bell J; Koach J; Smith S; Sekyere E; Thomas WD; Norris MD; Haber M; Lovejoy DB; Richardson DR; Marshall GM, 2009, 'ATP7A is a novel target of retinoic acid receptor beta(2) in neuroblastoma cells', British Journal of Cancer, 100, pp. 96 - 105, http://dx.doi.org/10.1038/sj.bjc.6604833

Sutton R; Venn NC; Tolisano J; Bahar AY; Giles JE; Ashton LJ; Teague L; Rigutto G; Waters K; Marshall GM; Haber M; Norris MD; Giles J, 2009, 'Clinical significance of minimal residual disease at day 15 and at the end of therapy in childhood acute lymphoblastic leukaemia', British Journal of Haematology, 146, pp. 292 - 299, http://dx.doi.org/10.1111/j.1365-2141.2009.07744.x

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