By Professor Murray David Norris

Journal articles

Haber M; Madafiglio J; Norris MD, 1993, 'Methotrexate cytotoxicity determination using the MTT assay following enzymatic depletion of thymidine and hypoxanthine', Journal of Cancer Research and Clinical Oncology, 119, pp. 315 - 317, http://dx.doi.org/10.1007/BF01208836

Gilbert J; Norris MD; Haber M; Kavallaris M; Marshall GM; Stewart BW, 1993, 'Determination of n-myc gene amplification in neuroblastoma by differential polymerase chain reaction', Molecular and Cellular Probes, 7, pp. 227 - 234, http://dx.doi.org/10.1006/mcpr.1993.1033

Selig RA; Madafiglio J; Haber M; Norris MD; White L; Stewart BW, 1993, 'Ferritin production and desferrioxamine cytotoxicity in human neuroblastoma cell lines', Anticancer Research, 13, pp. 721 - 725

Kavallaris M; Madafiglio J; Norris MD; Haber M, 1993, 'Resistance to Tetracycline, a Hydrophilic Antibiotic, Is Mediated by P-Glycoprotein in Human Multidrug-Resistant Cells', Biochemical and Biophysical Research Communications, 190, pp. 79 - 85, http://dx.doi.org/10.1006/bbrc.1993.1013

TELFORD DJ; KAVALLARIS M; WHITE L; NORRIS MD; BRIAN MJ; STEWART BW, 1992, 'Association of N‐myc amplification with neuroblastoma: The Australian and New Zealand experience', Journal of Paediatrics and Child Health, 28, pp. 58 - 63, http://dx.doi.org/10.1111/j.1440-1754.1992.tb02619.x

Kavallaris M; Haber M; Norris MD; Matherly LH; Stewart BW, 1991, 'Characterization of Mechanisms Mediating Drug Resistance in Human Leukemic Cells Selected with High Concentration Methotrexate', Pteridines, 3, pp. 119 - 121, http://dx.doi.org/10.1515/pteridines.1991.3.12.119

Norris MD; Haber M; Kavallaris M; Brian MJ; Lutze LH; White L; Stewart BW, 1991, 'Reduced drug accumulation as the mechanism of extreme clinical resistance to methotrexate in the human T‐cell leukemia xenograft, LALW‐2', Cancer, 68, pp. 981 - 987, http://dx.doi.org/10.1002/1097-0142(19910901)68:5<981::AID-CNCR2820680512>3.0.CO;2-W

Stewart BW; Kavallaris M; Catchpoole D; Norris MD, 1991, 'Two classes of single-stranded regions evident in deproteinized preparations of replicating DNA isolated from mammalian cells', Experimental Cell Research, 192, pp. 639 - 642, http://dx.doi.org/10.1016/0014-4827(91)90087-B

Kavallaris M; Haber M; Norris MD; Pittman SM; Reed C; Stewart BW, 1990, 'Phenotypic and cytogenetic analysis of atypical multidrug resistance in human leukaemic cells selected with methotrexate at high concentration', Cancer Letters, 51, pp. 193 - 201, http://dx.doi.org/10.1016/0304-3835(90)90102-4

White L; Norris MD; Marshall GM; Stewart BW; Tobias V; Sosula L; Trickett A, 1990, 'Heterotransplantation of Human Lymphoid Neoplasms Using a Nude Mouse Intraocular Xenograft Model', Cancer Research, 50, pp. 3078 - 3086

Norris MD; Haber M; King M; Davey RA, 1989, 'Atypical multidrug resistance in CCRF-CEM cells selected for high level methotrexate resistance: Reactivity to monoclonal antibody C219 in the absence of P-glycoprotein expression', Biochemical and Biophysical Research Communications, 165, pp. 1435 - 1441, http://dx.doi.org/10.1016/0006-291X(89)92764-2

Haber M; Norris MD; Kavallaris M; White L; Stewart BW; Bell DR; Davey RA, 1989, 'Atypical Multidrug Resistance in a Therapy-induced Drug-resistant Human Leukemia Cell Line (LALW-2): Resistance to Vinca Alkaloids Independent of P-Glycoprotein', Cancer Research, 49, pp. 5281 - 5287

Haber M; Reed C; Kavallaris M; Norris MD; Stewart BW, 1989, 'Resistance to drugs associated with the multidrug resistance phenotype following selection with high-concentration methotrexate', Journal of the National Cancer Institute, 81, pp. 1250 - 1254, http://dx.doi.org/10.1093/jnci/81.16.1250

White L; Haber M; Brian MJ; Norris MD; Trickett A; Sosula L; Tiley C; Stewart BW, 1989, 'Therapy‐induced drug resistance in a human leukemia line (LALW‐2)', Cancer, 63, pp. 2103 - 2110, http://dx.doi.org/10.1002/1097-0142(19890601)63:11<2103::AID-CNCR2820631106>3.0.CO;2-N

Seshadri R; Matthews C; Norris MD; Brian MJ, 1988, 'N-myc amplified in retinoblastoma cell line FMC-RB1', Cancer Genetics and Cytogenetics, 33, pp. 25 - 27, http://dx.doi.org/10.1016/0165-4608(88)90045-3

Norris MD; Stewart BW, 1988, 'Sizing of single-stranded regions in double-stranded DNA by preparative benzoylated DEAE-cellulose chromatography', FEBS Letters, 228, pp. 223 - 227, http://dx.doi.org/10.1016/0014-5793(88)80003-6

Norris MD; Brian MJ; Vowels MR; Stewart BW, 1988, 'N-myc amplification in Wilms' tumor', Cancer Genetics and Cytogenetics, 30, pp. 187 - 189, http://dx.doi.org/10.1016/0165-4608(88)90112-4

Ward EJ; Haber M; Norris MD; Stewart BW, 1985, 'Single-Strand-Specific Degradation of DNA during Isolation of Rat Liver Nuclei†', Biochemistry, 24, pp. 5803 - 5809, http://dx.doi.org/10.1021/bi00342a018

Conference Papers

Vijayasubhash V; Cowley M; Haber M; Sutton R; Trahair T; Norris M; marshall G; Kamili A; Atkinson C; Ekert P; Huang L; Venn N; Fletcher J; Henderson M, 2021, 'Analysis of DNA minimal residual disease markers in pediatric solid cancers using quantitative real time PCR and droplet digital PCR', in Analysis of DNA minimal residual disease markers in pediatric solid cancers using quantitative real time PCR and droplet digital PCR, American Association for Cancer Research (AACR), PA, Philadelphia, pp. 639 - 639, presented at AACR 2021, PA, Philadelphia, 10 April 2021 - 21 May 2021, http://dx.doi.org/10.1158/1538-7445.AM2021-639

Khan A; Gamble L; Upton D; Yu D; Ehteda A; Pandher R; Mayoh C; Burns M; Norris M; Haber M; Tsoli M; Ziegler D, 2020, 'POLYAMINE PATHWAY INHIBITION IS A POTENT NOVEL THERAPEUTIC STRATEGY AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 289 - 290, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100066&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ehteda A; Franshaw L; Liu J; Joshi S; Simon S; Pang CNI; Giorgi F; Pandher R; Ung C; Tolhurst O; Mayoh C; Khan A; Hayden E; Gopalakrishnan A; Trebilcock P; Upton D; Lehmann R; George S; Vittorio O; Tsoli M; Gurova K; Gudkov AG; Norris MD; Haber M; Ziegler DS, 2020, 'TARGETING FACILITATES CHROMATIN TRANSCRIPTION (FACT) AS A NOVEL STRATEGY FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) THAT ENHANCES RESPONSE TO HISTONE DEACETYLASE (HDAC) INHIBITION', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 292 - 292, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100077&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Haber M; Gamble L; Xiao L; Pandher R; Somers K; Murray J; Khan A; Yu D; Franshaw L; Burns MR; Tsoli M; Ehteda A; Cesare A; O’Connor A; Mussai F; de Santo C; Cheng P; Korotchkina L; Gurova K; Tyrrell V; Mould E; Lau L; Quang DAK; Mayoh C; Arndt G; Barahona P; Failes T; Fletcher J; Bolanos NF; Gauthier M-E; Gifford A; Grebert-Wade D; Kamili A; Kumar A; Nagabushan S; O’Brien T; Strong P; Sherstyuk A; Thomas D; Trahair T; Tucker K; Warby M; Wong M; Xie J; Evans K; Lock R; Chernova OB; Henderson M; Gudkov AV; Ekert P; Cowley MJ; Marshall GM; Ziegler DS; Norris MD, 2020, 'Abstract IA13: Molecular targeted therapies and precision medicine for children with neuroblastoma and other refractory malignancies', in Cancer Research, American Association for Cancer Research (AACR), pp. ia13 - ia13, http://dx.doi.org/10.1158/1538-7445.pedca19-ia13

Valli E; Xue C; Cheung L; Gamble L; Pandher R; Giacomo SD; Burkhart C; Fedtsova N; Ferrucci F; Makarov S; Telfer T; Codd R; Scott D; Perini G; Osterman A; Gudkov A; Norris M; Haber M, 2019, 'Abstract 2616: A novel iron-chelating agent reduces MYC transcription via E2F gene family regulation', in Cancer Research, American Association for Cancer Research (AACR), pp. 2616 - 2616, http://dx.doi.org/10.1158/1538-7445.am2019-2616

Valli E; Xue C; Cheung L; Gamble L; Pandher R; Giacomo SD; Burkhart C; Fedtsova N; Ferrucci F; Makarov S; Telfer T; Codd R; Scott D; Perini G; Osterman A; Gudkov A; Norris M; Haber M, 2019, 'Abstract 2616: A novel iron-chelating agent reduces MYC transcription via E2F gene family regulation', American Association for Cancer Research (AACR), pp. 2616 - 2616, presented at Molecular and Cellular Biology / Genetics, http://dx.doi.org/10.1158/1538-7445.sabcs18-2616

Nagy Z; Kanikevich M; Koach J; Mayoh C; Carter D; Liu T; Du Y; Jiang C; Haber M; Norris M; Cheung B; Marshall G, 2019, 'Abstract 3659: Alyref is a novel binding partner and co-factor for MYCN-driven oncogenesis in neuroblastoma', American Association for Cancer Research (AACR), pp. 3659 - 3659, presented at Tumor Biology, http://dx.doi.org/10.1158/1538-7445.sabcs18-3659

Hanssen KM; Gana CC; Wheatley MS; Yu DM; Flemming CL; Young R; Wright GM; Conseil G; Kennedy CJ; deFazio A; Solomon B; Cole SP; Norris MD; Haber M; Fletcher JI, 2019, 'Abstract 3809: Modulation of MRP1 activity reverses chemotherapy resistance in adult cancer cells', in Cancer Research, American Association for Cancer Research (AACR), pp. 3809 - 3809, http://dx.doi.org/10.1158/1538-7445.am2019-3809

Hanssen KM; Gana CC; Wheatley MS; Yu DM; Flemming CL; Young R; Wright GM; Conseil G; Kennedy CJ; deFazio A; Solomon B; Cole SP; Norris MD; Haber M; Fletcher JI, 2019, 'Abstract 3809: Modulation of MRP1 activity reverses chemotherapy resistance in adult cancer cells', American Association for Cancer Research (AACR), pp. 3809 - 3809, presented at Experimental and Molecular Therapeutics, http://dx.doi.org/10.1158/1538-7445.sabcs18-3809

Xiao L; Murray J; Ehteda A; Somers C; Mayoh C; Gamble L; Pandher R; Tsoli M; Eden G; Allan S; Sarraf S; Kosciolek A; Ziegler D; Henderson M; Issaeva N; Gurova K; Gudkov A; Haber M; Norris M, 2018, 'Chromatin destabilization by CBL0137 and panobinostat leads to complete tumour regression of childhood neuroblastoma in immunocompetent transgenic mice', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, IRELAND, Dublin, pp. E25 - E25, presented at 30th EORTC-NCI-AACR Symposium, IRELAND, Dublin, 13 November 2018 - 16 November 2018, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000461258600045&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Tee AE; Liu PY; Milazzo G; Hannan KM; Maag J; Bartonicek N; Song R; Jiang CC; Zhang XD; Norris MD; Haber M; Marshall GM; Li J; Vandesompele J; Mattick JS; Mestdagh P; Perini G; Hannan RD; Dinger ME; Liu T, 2018, 'Abstract 2453: Eradication of neuroblastoma by suppressing the expression of a single noncoding RNA', in Cancer Research, American Association for Cancer Research (AACR), pp. 2453 - 2453, http://dx.doi.org/10.1158/1538-7445.am2018-2453

Somers K; Middlemiss S; Biktasova A; Karsa M; Cheung L; Kosciolek A; Evans K; Mayoh C; Kees UR; Korotchkina L; Chernova OB; Lock RB; Gudkov AV; Haber M; Norris MD; Henderson MJ, 2017, 'Abstract 1175: Inhibition of NAMPT as a novel therapeutic strategy for infant leukemia', in Cancer Research, American Association for Cancer Research (AACR), pp. 1175 - 1175, http://dx.doi.org/10.1158/1538-7445.am2017-1175

Gao J; Somers K; Hannan KM; Fletcher JI; Liu B; Hannan RD; Pearson RB; Haber M; Norris MD; Henderson MJ, 2017, 'Abstract 1956: ABCE1 regulates the translational profile of neuroblastoma to drive tumor progression', in Cancer Research, American Association for Cancer Research (AACR), pp. 1956 - 1956, http://dx.doi.org/10.1158/1538-7445.am2017-1956

Burns MR; Fosnaugh K; Palfreyman MG; Gamble L; Murray J; Allan S; Eden G; Sarraf S; Norris M; Ziegler D; Haber M, 2017, 'Abstract 2006: AMX-513 polyamine depletion therapy inhibits tumor growth and reverses immunosuppression in cancers including MYC-driven neuroblastoma and pancreatic cancer', in Cancer Research, American Association for Cancer Research (AACR), pp. 2006 - 2006, http://dx.doi.org/10.1158/1538-7445.am2017-2006

Flynn AT; Vu A; Liu K; Scadden E; Attiyeh E; Norris M; Haber M; Hogarty M, 2017, 'Abstract 4883: Targeting tumor-amplified ODC1 with difluoromethylornithine (DFMO) inhibits global protein translation and has antitumor activity in neuroblastoma', in Cancer Research, American Association for Cancer Research (AACR), pp. 4883 - 4883, http://dx.doi.org/10.1158/1538-7445.am2017-4883

Gana CC; Hanssen K; Yu DM; Flemming C; Norris M; Haber M; Fletcher J, 2017, 'Abstract 4056: A modulator of multidrug resistance protein 1 selectively depletes glutathione and synergizes with L-buthionine sulfoximine to sensitize MRP1-expressing cancer cells to chemotherapy', in Cancer Research, American Association for Cancer Research (AACR), DC, Washington, pp. 4056 - 4056, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), DC, Washington, 01 April 2017 - 05 April 2017, http://dx.doi.org/10.1158/1538-7445.am2017-4056

Vittorio O; Brandl M; Cirillo G; Kimpton K; Hinde E; Duong HTT; Boyer C; Flemming C; Yee EMH; Kumar N; Parmar A; Pascali G; Charil A; Haber M; Norris M; Kavallaris M, 2016, 'Abstract 1340: Dextran-Catechin conjugate: An anticancer nano-modified natural compound targeting copper metabolism in neuroblastoma', in Cancer Research, American Association for Cancer Research (AACR), pp. 1340 - 1340, http://dx.doi.org/10.1158/1538-7445.am2016-1340

Xue C; Yu DM; Gherardi S; Koach J; Milazzo G; Gamble L; Liu B; Russell A; Liu T; Cheung BB; Marshall GM; Perini G; Haber M; Norris MD, 2016, 'Abstract 2450: MYCN and TFAP4 promote neuroblastoma malignancy by cooperating in the regulation a subset of target genes involved in cancer cell growth and metastasis', in Cancer Research, American Association for Cancer Research (AACR), pp. 2450 - 2450, http://dx.doi.org/10.1158/1538-7445.am2016-2450

Koach J; Murray JE; McCarroll J; Milazzo G; Perini G; Haber M; Norris MD; Fletcher JI; Cheung BB; Marshall GM, 2016, 'Targeting PA2G4, a novel MYCN co-factor, for the treatment of neuroblastoma', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, pp. S7 - S7, http://dx.doi.org/10.1016/S0959-8049(16)61016-X

Gonzales-Aloy E; Norris MD; Wang JY, 2016, 'Abstract 1917: Suppression of miR-101a contributes to leukemogenesis by regulating epigenetic and pro-survival pathways in MLL AML stem cells', in Cancer Research, American Association for Cancer Research (AACR), LA, New Orleans, pp. 1917 - 1917, presented at 107th Annual Meeting of the American-Association-of-Cancer-Research (AACR), LA, New Orleans, 16 April 2016 - 20 April 2016, http://dx.doi.org/10.1158/1538-7445.am2016-1917

Wadham C; Saletta F; Byrne JA; Trahair T; Ziegler DS; McCowage G; Marshall G; Haber M; Norris M, 2016, 'Abstract 51: Molecular profiling of relapsed childhood cancer', in Clinical Cancer Research, American Association for Cancer Research (AACR), pp. 51 - 51, http://dx.doi.org/10.1158/1557-3265.pmsclingen15-51

Carter DR; Murray J; Cheung BB; Kalla H; Gamble L; Tsang J; Sutton S; Koach J; Syed S; Gifford A; Issaeva N; Biktasova A; Atmadibrata B; Sun Y; Sokolowski N; Ling D; Kim PY; Webber H; Clark A; Ruhle M; Liu B; Oberthuer A; Fischer M; Byrne J; Saletta F; Purmal A; Ziegler D; Liu T; Gurova KV; Gudkov AV; Norris MD; Haber M; Marshall GM, 2015, 'Abstract PR09: MYCN and is a therapeutic target in neuroblastoma', in Molecular Cancer Research, American Association for Cancer Research (AACR), pp. pr09 - pr09, http://dx.doi.org/10.1158/1557-3125.myc15-pr09

Williams R; Russell A; Bongers A; Sagnella S; Fife C; Jessup W; DeFazio A; Chenevix-Trench G; Haber M; Norris M; Henderson M, 2015, 'Abstract 313: Examining the role of ABCA1 cholesterol transporter in ovarian cancer spheroids', in Cancer Research, American Association for Cancer Research (AACR), pp. 313 - 313, http://dx.doi.org/10.1158/1538-7445.am2015-313

Kao FCL; Failes T; Arndt GM; Norris M; Kavallaris M, 2015, 'Abstract 3660: Discovery of a small molecule TUBB3/βIII-tubulin modulator in lung cancer', in Cancer Research, American Association for Cancer Research (AACR), pp. 3660 - 3660, http://dx.doi.org/10.1158/1538-7445.am2015-3660

O'Brien R; Maritz MF; Kong CF; Purgato S; Liu B; Yang C; Russell A; Murray J; Flemming C; Haber M; Perini G; Norris MD; Fletcher JI; Mackenzie KL, 2015, 'Abstract 488: High DKC1 expression supports neuroblastoma tumor cell proliferation and is strongly associated with poor patient outcomes', in Cancer Research, American Association for Cancer Research (AACR), pp. 488 - 488, http://dx.doi.org/10.1158/1538-7445.am2015-488

Koach J; Liu B; Bell JL; Hüttelmaier S; Liu T; Carter DR; Haber M; Norris MD; Fletcher J; Cheung BB; Marshall GM, 2015, 'Abstract 962: PA2G4 predicts poor prognosis in neuroblastoma patients and promotes neuroblastoma progression by enhancing MYCN protein stability', in Cancer Research, American Association for Cancer Research (AACR), pp. 962 - 962, http://dx.doi.org/10.1158/1538-7445.am2015-962

Carter DR; Murray J; Cheung BB; Kalla H; Gamble L; Tsang J; Sutton S; Koach J; Syed S; Gifford A; Issaeva N; Biktasova A; Atmadibrata B; Sun Y; Sokolowski N; Ling D; Kim PY; Webber H; Clark A; Ruhle M; Liu B; Oberthuer A; Fischer M; Byrne J; Saletta F; Purmal A; Ziegler D; Liu T; Gurova KV; Gudkov AV; Norris MD; Haber M; Marshall GM, 2015, 'MYCN and is a therapeutic target in neuroblastoma', in MOLECULAR CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, La Jolla, presented at AACR Special Conference on Myc - From Biology to Therapy, CA, La Jolla, 07 January 2015 - 10 January 2015, http://dx.doi.org/10.1158/1557-3125,MYC15-PRO9

Hedditch EL; Henderson MJ; Russell AJ; Gao B; Emmanuel C; Williams RT; Flemming C; Johnatty S; George J; MacGregor S; Bowtell D; Chenevix-Trench G; Defazio A; Norris MD; Haber M, 2015, 'ASSOCIATION OF ABCA1 CHOLESTEROL TRANSPORTER WITH POOR OUTCOME AND AGGRESSIVE PHENOTYPE IN SEROUS OVARIAN CANCER', in Asia-Pacific Journal of Clinical Oncology, WILEY-BLACKWELL, pp. 114 - 114

Dietrich PA; Norris MD; Wang JY, 2014, 'GNA13, a Novel Component of the GPR84/Beta-Catenin Signaling Axis in AML Stem Cells, Regulates the Maintenance of MLLAF9 Leukemogenesis', in Blood, American Society of Hematology, pp. 3577, http://dx.doi.org/10.1182/blood.v124.21.3577.3577

Heong V; Topp M; Khambatta V; Rutkowski R; Ananda S; Wong S; McNally O; Swisher E; Lindeman G; Haber M; Norris M; Haluska P; Wakefield M; Bowtell D; Scott CL, 2014, 'NOVEL STRATEGIES TO TARGET THE C5 SUBCLASS OF HIGH-GRADE SEROUS OVARIAN CANCER (HGSC) USING PATIENT-DERIVED XENOGRAFTS.', in INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, LIPPINCOTT WILLIAMS & WILKINS, pp. 1018 - 1019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344966501301&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Haber M; Murray J; Gamble L; Carnegie-Clark A; Webber H; Ruhle M; Carter D; Oberthur A; Fischer M; Ziegler D; Marshall GM; Gurova K; Burkhart C; Purmal A; Gudkov AV; Norris MD, 2014, '422 CBL0137, a novel NFkB suppressor and p53 activator, is highly effective in pre-clinical models of neuroblastoma', in European Journal of Cancer, Elsevier, pp. 135, http://dx.doi.org/10.1016/s0959-8049(14)70548-9

Haber M; Murray J; Carnegie-Clark A; Webber H; Marshall GM; Gurova KV; Burkhart CA; Purmal A; Gudkov AV; Norris MD, 2013, 'Abstract 2759: Anticancer compound curaxin CBL0137, that simultaneously suppresses NF-κB and activates p53, is highly effective in two independent mouse models of neuroblastoma.', in Cancer Research, American Association for Cancer Research (AACR), pp. 2759 - 2759, http://dx.doi.org/10.1158/1538-7445.am2013-2759

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