ORCID as entered in ROS
https://orcid.org/0000-0002-0632-4589
Select Publications
Journal articles
, 1993, 'Ferritin production and desferrioxamine cytotoxicity in human neuroblastoma cell lines', Anticancer Research, 13, pp. 721 - 725
, 1993, 'Resistance to Tetracycline, a Hydrophilic Antibiotic, Is Mediated by P-Glycoprotein in Human Multidrug-Resistant Cells', Biochemical and Biophysical Research Communications, 190, pp. 79 - 85, http://dx.doi.org/10.1006/bbrc.1993.1013
, 1992, 'Association of N‐myc amplification with neuroblastoma: The Australian and New Zealand experience', Journal of Paediatrics and Child Health, 28, pp. 58 - 63, http://dx.doi.org/10.1111/j.1440-1754.1992.tb02619.x
, 1991, 'Characterization of Mechanisms Mediating Drug Resistance in Human Leukemic Cells Selected with High Concentration Methotrexate', Pteridines, 3, pp. 119 - 121, http://dx.doi.org/10.1515/pteridines.1991.3.12.119
, 1991, 'Reduced drug accumulation as the mechanism of extreme clinical resistance to methotrexate in the human T‐cell leukemia xenograft, LALW‐2', Cancer, 68, pp. 981 - 987, http://dx.doi.org/10.1002/1097-0142(19910901)68:5<981::AID-CNCR2820680512>3.0.CO;2-W
, 1991, 'Two classes of single-stranded regions evident in deproteinized preparations of replicating DNA isolated from mammalian cells', Experimental Cell Research, 192, pp. 639 - 642, http://dx.doi.org/10.1016/0014-4827(91)90087-B
, 1990, 'Phenotypic and cytogenetic analysis of atypical multidrug resistance in human leukaemic cells selected with methotrexate at high concentration', Cancer Letters, 51, pp. 193 - 201, http://dx.doi.org/10.1016/0304-3835(90)90102-4
, 1990, 'Heterotransplantation of Human Lymphoid Neoplasms Using a Nude Mouse Intraocular Xenograft Model', Cancer Research, 50, pp. 3078 - 3086
, 1989, 'Atypical multidrug resistance in CCRF-CEM cells selected for high level methotrexate resistance: Reactivity to monoclonal antibody C219 in the absence of P-glycoprotein expression', Biochemical and Biophysical Research Communications, 165, pp. 1435 - 1441, http://dx.doi.org/10.1016/0006-291X(89)92764-2
, 1989, 'Atypical Multidrug Resistance in a Therapy-induced Drug-resistant Human Leukemia Cell Line (LALW-2): Resistance to Vinca Alkaloids Independent of P-Glycoprotein', Cancer Research, 49, pp. 5281 - 5287
, 1989, 'Resistance to drugs associated with the multidrug resistance phenotype following selection with high-concentration methotrexate', Journal of the National Cancer Institute, 81, pp. 1250 - 1254, http://dx.doi.org/10.1093/jnci/81.16.1250
, 1989, 'Therapy‐induced drug resistance in a human leukemia line (LALW‐2)', Cancer, 63, pp. 2103 - 2110, http://dx.doi.org/10.1002/1097-0142(19890601)63:11<2103::AID-CNCR2820631106>3.0.CO;2-N
, 1988, 'N-myc amplified in retinoblastoma cell line FMC-RB1', Cancer Genetics and Cytogenetics, 33, pp. 25 - 27, http://dx.doi.org/10.1016/0165-4608(88)90045-3
, 1988, 'Sizing of single-stranded regions in double-stranded DNA by preparative benzoylated DEAE-cellulose chromatography', FEBS Letters, 228, pp. 223 - 227, http://dx.doi.org/10.1016/0014-5793(88)80003-6
, 1988, 'N-myc amplification in Wilms' tumor', Cancer Genetics and Cytogenetics, 30, pp. 187 - 189, http://dx.doi.org/10.1016/0165-4608(88)90112-4
, 1985, 'Single-Strand-Specific Degradation of DNA during Isolation of Rat Liver Nuclei†', Biochemistry, 24, pp. 5803 - 5809, http://dx.doi.org/10.1021/bi00342a018
Conference Papers
, 2021, 'Analysis of DNA minimal residual disease markers in pediatric solid cancers using quantitative real time PCR and droplet digital PCR', in Analysis of DNA minimal residual disease markers in pediatric solid cancers using quantitative real time PCR and droplet digital PCR, American Association for Cancer Research (AACR), PA, Philadelphia, pp. 639 - 639, presented at
, 2020, 'POLYAMINE PATHWAY INHIBITION IS A POTENT NOVEL THERAPEUTIC STRATEGY AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 289 - 290, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100066&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2020, 'TARGETING FACILITATES CHROMATIN TRANSCRIPTION (FACT) AS A NOVEL STRATEGY FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) THAT ENHANCES RESPONSE TO HISTONE DEACETYLASE (HDAC) INHIBITION', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 292 - 292, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100077&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2020, 'Abstract IA13: Molecular targeted therapies and precision medicine for children with neuroblastoma and other refractory malignancies', in Cancer Research, American Association for Cancer Research (AACR), pp. IA13 - IA13, http://dx.doi.org/10.1158/1538-7445.pedca19-ia13
, 2019, 'Abstract 2616: A novel iron-chelating agent reduces MYC transcription via E2F gene family regulation', in Molecular and Cellular Biology / Genetics, American Association for Cancer Research, pp. 2616 - 2616, presented at
, 2019, 'Abstract 3659: Alyref is a novel binding partner and co-factor for MYCN-driven oncogenesis in neuroblastoma', in Tumor Biology, American Association for Cancer Research, pp. 3659 - 3659, presented at
, 2019, 'Abstract 3809: Modulation of MRP1 activity reverses chemotherapy resistance in adult cancer cells', in Cancer Research, American Association for Cancer Research (AACR), pp. 3809 - 3809, http://dx.doi.org/10.1158/1538-7445.am2019-3809
, 2019, 'A novel iron-chelating agent reduces MYC transcription via E2F gene family regulation', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, GA, Atlanta, presented at
, 2019, 'Modulation of MRP1 activity reverses chemotherapy resistance in adult cancer cells', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, GA, Atlanta, presented at
, 2018, 'Chromatin destabilization by CBL0137 and panobinostat leads to complete tumour regression of childhood neuroblastoma in immunocompetent transgenic mice', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, IRELAND, Dublin, pp. E25 - E25, presented at
, 2018, 'Eradication of neuroblastoma by suppressing the expression of a single noncoding RNA', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, IL, Chicago, presented at
, 2017, 'ABCE1 regulates the translational profile of neuroblastoma to drive tumor progression', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, presented at
, 2017, 'Abstract 4056: A modulator of multidrug resistance protein 1 selectively depletes glutathione and synergizes with L-buthionine sulfoximine to sensitize MRP1-expressing cancer cells to chemotherapy', in Cancer Research, American Association for Cancer Research (AACR), DC, Washington, pp. 4056 - 4056, presented at
, 2017, 'AMX-513 polyamine depletion therapy inhibits tumor growth and reverses immunosuppression in cancers including MYC-driven neuroblastoma and pancreatic cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, presented at
, 2017, 'Inhibition of NAMPT as a novel therapeutic strategy for infant leukemia', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, presented at
, 2017, 'Targeting tumor-amplified ODC1 with difluoromethylornithine (DFMO) inhibits global protein translation and has antitumor activity in neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, presented at
, 2016, 'Targeting PA2G4, a novel MYCN co-factor, for the treatment of neuroblastoma', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, pp. S7 - S7, http://dx.doi.org/10.1016/S0959-8049(16)61016-X
, 2016, 'Abstract 1917: Suppression of miR-101a contributes to leukemogenesis by regulating epigenetic and pro-survival pathways in MLL AML stem cells', in Cancer Research, American Association for Cancer Research (AACR), LA, New Orleans, pp. 1917 - 1917, presented at
, 2016, 'Dextran-Catechin conjugate: An anticancer nano-modified natural compound targeting copper metabolism in neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, LA, New Orleans, presented at
, 2016, 'MYCN and TFAP4 promote neuroblastoma malignancy by cooperating in the regulation a subset of target genes involved in cancer cell growth and metastasis', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, LA, New Orleans, presented at
, 2015, 'Abstract PR09: MYCN and is a therapeutic target in neuroblastoma', in Molecular Cancer Research, American Association for Cancer Research (AACR), pp. PR09 - PR09, http://dx.doi.org/10.1158/1557-3125.myc15-pr09
, 2015, 'Molecular profiling of relapsed childhood cancer', in CLINICAL CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, UT, Salt Lake, presented at
, 2015, 'Discovery of a small molecule TUBB3/beta III-tubulin modulator in lung cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, PA, Philadelphia, presented at
, 2015, 'Examining the role of ABCA1 cholesterol transporter in ovarian cancer spheroids', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, PA, Philadelphia, presented at
, 2015, 'High DKC1 expression supports neuroblastoma tumor cell proliferation and is strongly associated with poor patient outcomes', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, PA, Philadelphia, presented at
, 2015, 'PA2G4 predicts poor prognosis in neuroblastoma patients and promotes neuroblastoma progression by enhancing MYCN protein stability', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, PA, Philadelphia, presented at
, 2015, 'MYCN and is a therapeutic target in neuroblastoma', in MOLECULAR CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, La Jolla, presented at
, 2015, 'ASSOCIATION OF ABCA1 CHOLESTEROL TRANSPORTER WITH POOR OUTCOME AND AGGRESSIVE PHENOTYPE IN SEROUS OVARIAN CANCER', in Asia-Pacific Journal of Clinical Oncology, WILEY-BLACKWELL, pp. 114 - 114
, 2014, 'GNA13, a Novel Component of the GPR84/Beta-Catenin Signaling Axis in AML Stem Cells, Regulates the Maintenance of MLLAF9 Leukemogenesis', in Blood, American Society of Hematology, pp. 3577, http://dx.doi.org/10.1182/blood.v124.21.3577.3577
, 2014, 'CBL0137, a novel NFkB suppressor and p53 activator, is highly effective in pre-clinical models of neuroblastoma', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, SPAIN, European Org Res & Treatment Canc, Barcelona, pp. 135 - 135, presented at
, 2014, 'NOVEL STRATEGIES TO TARGET THE C5 SUBCLASS OF HIGH-GRADE SEROUS OVARIAN CANCER (HGSC) USING PATIENT-DERIVED XENOGRAFTS.', in INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, LIPPINCOTT WILLIAMS & WILKINS, pp. 1018 - 1019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344966501301&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
, 2013, 'Anticancer compound curaxin CBL0137, that simultaneously suppresses NF-kappa B and activates p53, is highly effective in two independent mouse models of neuroblastoma.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Washington, DC, presented at
, 2013, 'MYCN coordinately regulates the entire polyamine gene pathway to drive polyamine biosynthesis in neuroblastoma, with expression of every synthetic and catabolic polyamine pathway gene being highly prognostic of clinical outcome', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, presented at
, 2013, 'The facilitates chromatin transcription (FACT) protein complex promotes neuroblastoma tumor initiation.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, presented at
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https://orcid.org/0000-0002-0632-4589