By Professor Nigel Turner

Journal articles

Fu YY; Zhang M; Turner N; Zhang LN; Dong TC; Gu M; Leslie SJ; Li JY; Nan FJ; Li J, 2013, 'A novel chemical uncoupler ameliorates obesity and related phenotypes in mice with diet-induced obesity by modulating energy expenditure and food intake', Diabetologia, 56, pp. 2297 - 2307, http://dx.doi.org/10.1007/s00125-013-2987-9

Seto JT; Quinlan KGR; Lek M; Zheng XF; Garton F; Macarthur DG; Hogarth MW; Houweling PJ; Gregorevic P; Turner N; Cooney GJ; Yang N; North KN, 2013, 'ACTN3 genotype infuences muscle performance through the regulation of calcineurin signaling', Journal of Clinical Investigation, 123, pp. 4255 - 4263, http://dx.doi.org/10.1172/JCI67691

Fiamoncini J; Turner N; Hirabara SM; Salgado TML; Marçal AC; Leslie S; Da Silva SMA; Deschamps FC; Luz J; Cooney GJ; Curi R, 2013, 'Enhanced peroxisomal β-oxidation is associated with prevention of obesity and glucose intolerance by fish oil-enriched diets', Obesity, 21, pp. 1200 - 1207, http://dx.doi.org/10.1002/oby.20132

Bell-Anderson KS; Funnell AP; Williams H; Mat Jusoh H; Scully T; Lim WF; Burdach J; Mak KS; Knights AJ; Hoy AJ; Nicholas HR; Sainsbury A; Turner N; Pearson R; Crossley M, 2013, 'Loss of Krüppel-like factor 3 (KLF3/BKLF) leads to upregulation of the insulin-sensitizing factor adipolin (FAM132A/CTRP12/C1qdc2).', , http://dx.doi.org/10.2337/db12-1745

Montgomery MK; Osborne B; Brown SHJ; Small L; Mitchell TW; Cooney GJ; Turner N, 2013, 'Contrasting metabolic effects of medium-versus long-chain fatty acids in skeletal muscle', Journal of Lipid Research, 54, pp. 3322 - 3333, http://dx.doi.org/10.1194/jlr.M040451

Iseli TJ; Turner N; Zeng XY; Cooney GJ; Kraegen EW; Yao S; Ye Y; James DE; Ye J, 2013, 'Activation of AMPK by Bitter Melon Triterpenoids Involves CaMKKB', PLoS ONE, 8, pp. Article number e62309, http://dx.doi.org/10.1371/journal.pone.0062309

Reznick J; Preston E; Wilks D; Beale S; Turner N; Cooney GJ, 2013, 'Altered feeding differentially regulates circadian rhythms and energy metabolism in liver and muscle of rats', Biochimica et Biophysica ACTA, 1832, pp. 228 - 238, http://dx.doi.org/10.1016/j.bbadis.2012.08.010

Turner N; Kowalski GM; Leslie SJ; Risis S; Yang C; Lee-Young RS; Babb JR; Meikle PJ; Lancaster GI; Henstridge DC; White PJ; Kraegen E; Marette A; Cooney GJ; Febbraio MA; Bruce CR, 2013, 'Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding', Diabetologia, 56, pp. 1638 - 1648, http://dx.doi.org/10.1007/s00125-013-2913-1

Montgomery MK; Hallahan NL; Brown S; Liu M; Mitchell T; Cooney GJ; Turner N, 2013, 'Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding', Diabetologia, 56, pp. 1129 - 1139, http://dx.doi.org/10.1007/s00125-013-2846-8

Oakes N; Kjellstedt A; Thalen P; Ljung B; Turner N, 2013, 'Roles of fatty acid oversupply and impaired oxidation in lipid accumulation in tissues of obese rats', Journal of Lipids, 2013, pp. 1 - 13, http://dx.doi.org/10.1155/2013/420754

Cleasby ME; Hoehn KL; Patel SA; Lawrence RT; Sawbridge L; Talbot NA; Turner N; Cooney GJ; Whitehead JP; Kraegen EW, 2012, 'Overexpression of the adiponectin receptor AdipoR1 in rat skeletal muscle amplifies local insulin sensitivity', DIABETOLOGIA, 55, pp. S244 - S245, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208826501338&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Montgomery MK; Maghzal GJ; Stocker R; Cooney GJ; Turner N, 2012, 'The beneficial effects of medium-chain fatty acids on metabolism and oxidative stress', BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 1817, pp. S122 - S122, http://dx.doi.org/10.1016/j.bbabio.2012.06.327

Tsoli M; Moore MM; Burg DW; Painter AB; Taylor R; Lockie SH; Turner N; Warren A; Cooney GJ; Oldfield BJ; Clark SJ; Robertson GR, 2012, 'Activation of thermogenesis in brown adipose tissue and dysregulated lipid metabolism associated with cancer cachexia in mice', Cancer Research, 72, pp. 4372 - 4382, http://dx.doi.org/10.1158/0008-5472.CAN-11-3536

Shi Y; Hammerle C; Lee IC; Turner N; Nguyen AD; Riepler S; Lin S; Sainsbury-Salis A; Herzog H; Zhang L, 2012, 'Adult-onset PYY overexpression in mice reduces food intake and increased lipogenic capacity', Neuropeptides, 46, pp. 173 - 182, http://dx.doi.org/10.1016/j.npep.2012.04.001

Ren L; Chan SMH; Zeng X; Laybutt DR; Iseli TJ; Sun R; Kraegen E; Cooney GJ; Turner N; Ye J, 2012, 'Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance', PLoS ONE, 7, pp. e30816, http://dx.doi.org/10.1371/journal.pone.0030816

Holt LJ; Turner N; Mokbel N; Trefely S; Kanzleiter T; Kaplan W; Ormandy CJ; Daly RJ; Cooney GJ, 2012, 'Grb10 regulates the development of fiber number in skeletal muscle', Federation of American Societies for Experimantal Biology Journal, 26, pp. 3658 - 3669, http://dx.doi.org/10.1096/fj.11-199349

Cheng K; De lghingaro-augusto V; Noland C; Turner N; Hallahan NL; Andrikopoulos S; Gunton J, 2012, 'High passage MIN6 cells have impaired insulin secretion with impaired glucose and lipid oxidation', PLoS One, 7, pp. e40868, http://dx.doi.org/10.1371/journal.pone.0040868

Luo X; Hutley LJ; Webster J; Kim Y; Liu DY; Newell FS; Widberg C; Bachmann A; Turner N; Prins JB; Yang G; Whitehead J; Schmitz-Peiffer C, 2012, 'Identification of BMP and activin membrane-bound inhibitor (BAMBI) as a potent negative regulator of adipogenesis and modulator of autocrine/paracrine adipogenic factors', Diabetes, 61, pp. 124 - 136, http://dx.doi.org/10.2337/db11-0998

Turner N; Leslie SJ; Hallahan NL; Cooney GJ, 2012, 'Metabolic defects induced by high-fat feeding in mice are rapidly reversed by a low-fat diet', BMC Proceedings, 6, http://dx.doi.org/10.1186/1753-6561-6-s3-p49

Turner N, 2012, 'New insight into obesity and metabolic disease through metabolite profiling', Journal of Metabonomics and Metabolites, 1, pp. 1000e101 - 1000e102, http://dx.doi.org/10.4172/jmbm.1000e102

Boden M; Brandon A; TidAng J; Preston E; Wilks D; Stuart E; Cleasby M; Turner N; Cooney GJ; Kraegen E, 2012, 'Overexpression of manganese superoxide dismutase ameliorates high-fat diet-induced insulin resistance in rat skeletal muscle', American Journal of Physiology - Endocrinology and Metabolism, 303, pp. e798 - e805, http://dx.doi.org/10.1152/ajpendo.00577.2011

Patel SA; Hoehn KL; Lawrence RT; Sawbridge L; Talbot NA; Tomsig JL; Turner N; Cooney GJ; Whitehead JP; Kraegen E; Cleasby ME, 2012, 'Overexpression of the adiponectin receptor AdipoR1 in rat skeletal muscle amplifies local insulin sensitivity', Endocrinology, 153, pp. 5231 - 5246, http://dx.doi.org/10.1210/en.2012-1368

Samocha-Bonet D; Campbell LV; Mori TA; Croft KD; Greenfield JR; Turner N; Heilbronn LK, 2012, 'Overfeeding reduces insulin sensitivity and increases oxidative stress, without altering markers of mitochondrial content and function in humans', PLoS One, 7, pp. e36320, http://dx.doi.org/10.1371/journal.pone.0036320

Hoehn KL; Turner N; Cooney GJ; James DE, 2012, 'Phenotypic discrepancies in acetyl-CoA carboxylase 2-deficient mice', The Journal of Biological Chemistry, 287, pp. 15801, http://dx.doi.org/10.1074/jbc.O112.356915

Hoeks J; Wright L; Jörgensen JA; Osborne B; Montgomery M; Cooney G; Schrauwen P; Turner N, 2012, 'PS - 46. SIRT3 overexpression in rat skeletal muscle does not alleviate high-fat diet-induced insulin resistance', Nederlands Tijdschrift voor Diabetologie, 10, pp. 130 - 130, http://dx.doi.org/10.1007/s12467-012-0080-5

Wright LE; Brandon A; Hoy A; Forsberg G; Lelliott CJ; Reznick J; Lofgren L; Oscarsson J; Cooney GJ; Turner N, 2011, 'Amelioration of lipid-induced insulin resistance in rat skeletal muscle by overexpression of Pgc-1beta involves reductions in long-chain acyl-CoA levels and oxidative stress', Diabetologia, 54, pp. 1417 - 1426, http://dx.doi.org/10.1007/s00125-011-2068-x

Ye J; TidAng J; Turner N; Zeng XY; Li HY; Cooney GJ; Wulff EM; Sauerberg P; Kraegen E, 2011, 'PPARdelta agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle', British Journal of Pharmacology, 163, pp. 556 - 566, http://dx.doi.org/10.1111/j.1476-5381.2011.01240.x

Cleasby M; Lau Q; Polkinghorne E; Patel S; Leslie SJ; Turner N; Cooney GJ; Xu A; Kraegen E, 2011, 'The adaptor protein APPL1 increases glycogen accumulation in rat skeletal muscle through activation of the PI3-kinase signalling pathway', Journal of Endocrinology, 210, pp. 81 - 92, http://dx.doi.org/10.1530/JOE-11-0039

Seto JT; Chan SM; Turner N; MacArthur D; Raftery J; Berman Y; Quinlan KG; Cooney GJ; Head SI; Yang N; North K, 2011, 'The effect of alpha-actinin-3 deficiency on muscle aging', Experimental Gerontology, 46, pp. 292 - 302, http://dx.doi.org/10.1016/j.exger.2010.11.006

Brandon A; Hoy AJ; Wright LE; Turner N; Hegarty BD; Iseli TJ; Xu X; Cooney GJ; Saha AK; Ruderman NB; Kraegen E; Hegarty B, 2011, 'The evolution of insulin resistance in muscle of the glucose infused rat', Archives of Biochemistry and Biophysics, 509, pp. 133 - 141, http://dx.doi.org/10.1016/j.abb.2011.03.008

Turner N; Mitchell TR; Else PL; Hulbert AJ, 2011, 'The omega-3 and omega-6 fats in meals: A proposal for a simple new label', Nutrition, 27, pp. 719 - 726, http://dx.doi.org/10.1016/j.nut.2010.07.019

Raddatz K; Turner N; Frangioudakis G; Liao BM; Pedersen DJ; Cantley J; Wilks D; Preston E; Hegarty BD; Leitges M; Raftery MJ; Biden TJ; Schmitz-Peiffer C, 2011, 'Time-dependent effects of Prkce deletion on glucose homeostasis and hepatic lipid metabolism on dietary lipid oversupply in mice.', Diabetologia, 54, pp. 1447 - 1456, http://dx.doi.org/10.1007/s00125-011-2073-0

, 2010, 'Errata', Diabetes, 59, pp. 1283 - 1283, http://dx.doi.org/10.2337/db10-er05a

Mitchell TW; Turner N; Else PL; Hulbert AJ; Hawley JA; Lee JS; Bruce CR; Blanksby SJ, 2010, 'The effect of exercise on the skeletal muscle phospholipidome of rats fed a high-fat diet.', International journal of molecular sciences, 11, pp. 3954 - 3964, http://dx.doi.org/10.3390/ijms11103954

Hoehn KL; Turner N; Swarbrick MM; Wilks D; Preston E; Phua Y; Joshi H; Furler SM; Larance M; Hegarty BD; Leslie SJ; Pickford R; Hoy AJ; Kraegen EW; James DE; Cooney GJ; Hegarty , 2010, 'Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity', Cell Metabolism, 11, pp. 70 - 76, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=20074529

Quinlan K; Seto JT; Turner N; Vandebrouck A; Floetenmeyer M; MacArthur D; Raftery J; Lek M; Yang N; Parton RG; Cooney GJ; North K, 2010, 'Alpha-actinin-3 deficiency results in reduced glycogen phosphorylase activity and altered calcium handling in skeletal muscle', Human Molecular Genetics, 19, pp. 1335 - 1346, http://dx.doi.org/10.1093/hmg/ddq010

Qui B-Y; Turner N; Li Y; Gu M; Huang M; Wu FF; Pang T; Nan F-J; Ye J; Li J; Li J, 2010, 'High-throughput assay for modulators of mitochondrial membrane potential identifies a novel compound with beneficial effects on db/db mice', Diabetes, 59, pp. 256-65, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19833880

Kanzleiter T; Preston E; Wilks D; Ho B; Benrick A; Reznick J; Heilbronn L; Turner N; Cooney GJ, 2010, 'Overexpression of the orphan receptor Nur77 alters glucose metabolism in rat muscle cells and rat muscle in vivo', Diabetologia, 53, pp. 1174 - 1183

Zhang L; Macia L; Turner N; Enriquez RF; Nguyen AD; Lin S; Lee NJ; Shi Y; Yulyaningsih E; Slack K; Baldock PA; Herzog H; Sainsbury-Salis A, 2010, 'Peripheral neuropeptide Y Y1 receptors regulate lipid oxidation and fat accretion', International journal of obesity, 34, pp. 357 - 373, http://dx.doi.org/10.1038/ijo.2009.232

Kanzleiter T; Wilks D; Preston E; Turner N; Heilbronn LK; Cooney GJ, 2010, 'Regulation des Glucosestoffwechsels im Muskel durch Nur77', Diabetologie und Stoffwechsel, 5, http://dx.doi.org/10.1055/s-0030-1253962

Leong GM; Kee AJ; Millard SM; Martel N; Eriksson N; Turner N; Cooney GJ; Hardeman EC; Muscat GE, 2010, 'The Ski proto-oncogene regulates body composition and suppresses lipogenesis.', International journal of obesity, 34, pp. 524 - 536, http://dx.doi.org/10.1038/ijo.2009.265

Zhang L; Riepler S; Turner N; Enriquez R; Lee IJ; Baldock PA; Herzog H; Sainsbury-Salis A, 2010, 'Y2 and Y4 receptor signalling synergistically act on energy expenditure and physical activity', American Journal of Physiology, 299, pp. 1618 - 1628

Hoy AJ; Brandon AE; Turner N; Watt MJ; Bruce CR; Cooney GJ; Kraegen EW, 2009, 'Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation', American Journal of Physiology - Endocrinology and Metabolism, 297, http://dx.doi.org/10.1152/ajpendo.90945.2008

Kraegen EW; Bruce CR; Hegarty BD; Ye J; Turner N; Cooney GJ; Hegarty , 2009, 'AMP-activated protein kinase and muscle insulin resistance', Frontiers in Bioscience, 14, pp. 4658 - 4672, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19273380

Turner N; Hariharan K; TidAng J; Frangioudakis G; Beale SM; Wright LE; Zeng XY; Leslie SJ; Li J; Kraegen EW; Cooney GJ; Ye J, 2009, 'Enhancement of muscle mitochondrial oxidative capacity and alterations in insulin action are lipid species dependent: potent tissue-specific effects of medium-chain fatty acids', Diabetes, 58, pp. 2547 - 2554, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19720794

Hegarty BD; Turner N; Cooney GJ; Kraegen EW; Hegarty , 2009, 'Insulin resistance and fuel homeostasis: The role of AMP-activated protein kinase', ACTA Physiologica, 196, pp. 129 - 145

Hoehn K; Salmon A; Hohnen-Behrens C; Turner N; Hoy A; Maghzal G; Stocker R; Van remmen H; Kraegen E; Cooney GJ; Richardson A; James DE, 2009, 'Insulin resistance is a cellular antioxidant defense mechanism', Proceedings of the National Academy of Sciences of the United States of America, 106, pp. 17787 - 17792, http://www.pnas.org/content/106/42/17787.long

Hoy AJ; Brandon A; Turner N; Watt M; Bruce CR; Cooney GJ; Kraegen EW, 2009, 'Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation', American Journal of Physiology - Endocrinology and Metabolism, 297, pp. 67 - 75

Bruce CR; Hoy AJ; Turner N; Watt MJ; Allen T; Carpenter K; Cooney GJ; Febbraio M; Kraegen EW, 2009, 'Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance', Diabetes, 58, pp. 550 - 558

Muhlhausler BS; Duffield JA; Ozanne SE; Pilgram C; Turner N; Morrison JL; McMillen IC, 2009, 'The transition from fetal growth restriction to accelerated postnatal growth: a potential role for insulin signalling in skeletal muscle', Journal of Physiology: London, 587, pp. 4199 - 4211, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19622603

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