Select Publications
Book Chapters
2024, 'Management of Primary Pancreatic Cancer', in Jankowski JAZ (ed.), Gastrointestinal Oncology: A Critical Multidisciplinary Team Approach, Wiley, pp. 386 - 406, http://dx.doi.org/10.1002/9781119756422.ch20
,2019, 'The use of star polymer nanoparticles for the delivery of siRNA to mouse orthotopic pancreatic tumor models', in RNA interference and cancer therapy : methods and protocols, pp. 329 - 353, http://dx.doi.org/10.1007/978-1-4939-9220-1_23
,2015, 'HSP47: The New Heat Shock Protein Therapeutic Target', in Topics in Medicinal Chemistry, Springer Berlin Heidelberg, http://dx.doi.org/10.1007/7355_2015_89
,2013, 'Nanotechnology, tumour biomarkers and RNA interference for personalized medicine applications', in Shiddiky MJA; Wee EJH; Rauf S; Trau M (ed.), Microfluidics, Nanotechnology and Disease Biomarkers for Personalized Medicine Applications, Nova Science Publishers, pp. 167 - 187, https://www.novapublishers.com/catalog/product_info.php?products_id=42427
,2008, 'Physiology of Experimental Pancreatitis', in , Wiley, pp. 91 - 106, http://dx.doi.org/10.1002/9781444300123.ch8
,Journal articles
2024, 'Development of a long term, ex vivo, patientderived explant model of endometrial cancer', PLoS ONE, 19, http://dx.doi.org/10.1371/journal.pone.0301413
,2024, 'Abstract B062: CRO67 has therapeutic potential against pancreatic tumor cells and cancer associated fibroblasts', Cancer Research, 84, pp. B062 - B062, http://dx.doi.org/10.1158/1538-7445.panca2023-b062
,2024, '1513P Impact of symptom and functional burden on survival in pancreatic ductal adenocarcinoma (PDAC)', Annals of Oncology, 35, pp. S925 - S925, http://dx.doi.org/10.1016/j.annonc.2024.08.1576
,2023, 'Standards for clinical trials for treating TB', International Journal of Tuberculosis and Lung Disease, 27, pp. 885 - 898, http://dx.doi.org/10.5588/ijtld.23.0341
,2023, 'A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer', Nature Cancer, 4, pp. 1326 - 1344, http://dx.doi.org/10.1038/s43018-023-00614-y
,2022, 'Abstract B076: βIII-Tubulin is a brake on extrinsic cell-death in pancreatic cancer', Cancer Research, 82, pp. B076 - B076, http://dx.doi.org/10.1158/1538-7445.panca22-b076
,2022, 'Abstract C073: CRO-67 is a novel therapeutic for pancreatic cancer: Implications for tumor and stromal reprogramming', Cancer Research, 82, pp. C073 - C073, http://dx.doi.org/10.1158/1538-7445.panca22-c073
,2022, 'Aerosol delivery of star polymer-siRNA nanoparticles as a therapeutic strategy to inhibit lung tumor growth', Biomaterials, 285, http://dx.doi.org/10.1016/j.biomaterials.2022.121539
,2022, 'Imaging Modalities for Early Detection of Pancreatic Cancer: Current State and Future Research Opportunities', Cancers, 14, http://dx.doi.org/10.3390/cancers14102539
,2021, 'How to exploit different endocytosis pathways to allow selective delivery of anticancer drugs to cancer cells over healthy cells', Chemical Science, 12, pp. 15407 - 15417, http://dx.doi.org/10.1039/d1sc04656j
,2021, 'Ex vivo culture of intact human patient derived pancreatic tumour tissue', Scientific Reports, 11, pp. 1944, http://dx.doi.org/10.1038/s41598-021-81299-0
,2021, 'ROR1 and ROR2 expression in pancreatic cancer', BMC Cancer, 21, http://dx.doi.org/10.1186/s12885-021-08952-9
,2021, 'Abstract IA-008: The KPC model has helped advance pancreatic cancer therapy: Disagree', Cancer Research, 81, http://dx.doi.org/10.1158/1538-7445.panca21-ia-008
,2021, 'Can the Shape of Nanoparticles Enable the Targeting to Cancer Cells over Healthy Cells?', Advanced Functional Materials, 31, http://dx.doi.org/10.1002/adfm.202007880
,2021, 'Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma determine response to slc7a11 inhibition', Cancer Research, 81, pp. 3461 - 3479, http://dx.doi.org/10.1158/0008-5472.CAN-20-2496
,2021, 'Interfacial Curvature in Confined Coculture Directs Stromal Cell Activity with Spatial Corralling of Pancreatic Cancer Cells', Advanced Biology, 5, pp. e2000525, http://dx.doi.org/10.1002/adbi.202000525
,2021, 'Does the microenvironment hold the hidden key for functional precision medicine in pancreatic cancer?', Cancers, 13, http://dx.doi.org/10.3390/cancers13102427
,2021, 'Cancer‐Associated Fibroblasts: Interfacial Curvature in Confined Coculture Directs Stromal Cell Activity with Spatial Corralling of Pancreatic Cancer Cells (Adv. Biology 6/2021)', Advanced Biology, 5, http://dx.doi.org/10.1002/adbi.202170064
,2021, 'Patient-derived pancreatic tumours in a dish: implications for real-time precision medicine', HPB, 23, pp. S235 - S235, http://dx.doi.org/10.1016/j.hpb.2020.11.590
,2020, 'Fibroblasts from distinct pancreatic pathologies exhibit disease-specific properties', Cancer Research, 80, pp. 2861 - 2873, http://dx.doi.org/10.1158/0008-5472.CAN-19-3534
,2020, 'Targeting the undruggable in pancreatic cancer using nano-based gene silencing drugs', Biomaterials, 240, http://dx.doi.org/10.1016/j.biomaterials.2019.119742
,2020, 'Identification of Novel Medulloblastoma Cell-Targeting Peptides for Use in Selective Chemotherapy Drug Delivery', Journal of Medicinal Chemistry, 63, pp. 2181 - 2193, http://dx.doi.org/10.1021/acs.jmedchem.9b00851
,2020, 'Bringing the pancreas patient back to the bench: Ex vivo culture of intact human patient derived pancreatic tumour tissue', , http://dx.doi.org/10.1101/2020.07.30.223925
,2019, 'CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan', Nature Communications, 10, pp. 3637, http://dx.doi.org/10.1038/s41467-019-10968-6
,2019, 'PDAC-associated fibroblasts are less responsive to an anti-fibrotic stimulus and more responsive to a positive regulator of fibroblast activation than normal activated fibroblasts', Pancreatology, 19, pp. S158 - S158, http://dx.doi.org/10.1016/j.pan.2019.05.423
,2018, 'ROBO2 is a stroma suppressor gene in the pancreas and acts via TGF-β signalling', Nature Communications, 9, http://dx.doi.org/10.1038/s41467-018-07497-z
,2018, 'Disease associated fibroblasts from various pancreatic disorders exhibit subtype specific genetic profile', Pancreatology, 18, pp. S94 - S94, http://dx.doi.org/10.1016/j.pan.2018.05.254
,2017, 'Inhibition of group 1 p21-activated kinases suppresses pancreatic stellate cell activation and increases survival of mice with pancreatic cancer', International Journal of Cancer, 140, pp. 2101 - 2111, http://dx.doi.org/10.1002/ijc.30615
,2017, 'MutY-Homolog (MYH) inhibition reduces pancreatic cancer cell growth and increases chemosensitivity', Oncotarget, 8, pp. 9216 - 9229, http://dx.doi.org/10.18632/oncotarget.13985
,2017, 'Altered Slit-Robo signalling activates TGF-beta signalling and stroma remodelling in the pancreas.', Pancreatology, 17, pp. S6 - S7, http://dx.doi.org/10.1016/j.pan.2017.05.020
,2016, 'Novel therapeutics and preclinical imaging for pancreatic cancer - View from the lab', Cancer Forum, 40, pp. 16 - 22
,2016, 'Delineating the Role of βIV-Tubulins in Pancreatic Cancer: βIVb-Tubulin Inhibition Sensitizes Pancreatic Cancer Cells to Vinca Alkaloids', Neoplasia (United States), 18, pp. 753 - 764, http://dx.doi.org/10.1016/j.neo.2016.10.011
,2016, 'A rationally optimized nanoparticle system for the delivery of RNA interference therapeutics into pancreatic tumors in vivo.', Biomacromolecules, 17, pp. 2337 - 2351, http://dx.doi.org/10.1021/acs.biomac.6b00185
,2016, 'Identification of novel signalling pathways dysregulated in pancreatic cancer-associated fibroblasts', Pancreatology, 16, pp. S31 - S31, http://dx.doi.org/10.1016/j.pan.2016.05.106
,2016, 'MutY-Homolog modulates pancreatic cancer cell survival and chemoresistance', Pancreatology, 16, pp. S5 - S5, http://dx.doi.org/10.1016/j.pan.2016.05.024
,2016, 'Targeting PAK1 in pancreatic stellate cells increases pancreatic cancer survival', Pancreatology, 16, pp. S26 - S27, http://dx.doi.org/10.1016/j.pan.2016.05.092
,2015, 'Hypoxia alters the recruitment of tropomyosins into the actin stress fibres of neuroblastoma cells', BMC Cancer, 15, http://dx.doi.org/10.1186/s12885-015-1741-8
,2015, 'Exploiting Base Excision Repair to Improve Therapeutic Approaches for Pancreatic Cancer', Frontiers in Nutrition, 2, pp. 10, http://dx.doi.org/10.3389/fnut.2015.00010
,2015, 'Antioxidant and anticancer capacity of saponin-enriched Carica papaya leaf extracts', International Journal of Food Science and Technology, 50, pp. 169 - 177, http://dx.doi.org/10.1111/ijfs.12618
,2015, 'Physicochemical, antioxidant and anti-cancer activity of a Eucalyptus robusta (Sm.) leaf aqueous extract', Industrial Crops and Products, 64, pp. 167 - 174, http://dx.doi.org/10.1016/j.indcrop.2014.10.061
,2015, 'Therapeutic targeting of polo-like kinase 1 using RNA-interfering nanoparticles (iNOPs) for the treatment of non-small cell lung cancer', Oncotarget, 6, pp. 12020 - 12034, http://dx.doi.org/10.18632/oncotarget.2664
,2015, 'βIII-Tubulin: A novel mediator of chemoresistance and metastases in pancreatic cancer', Oncotarget, 6, pp. 2235 - 2249, http://dx.doi.org/10.18632/oncotarget.2946
,2015, 'Simultaneous integration of microRNA and mRNA expression in the analysis of quiescent and activated human fibroblasts in the diseased pancreas', Pancreatology, 15, pp. S19 - S20, http://dx.doi.org/10.1016/j.pan.2015.05.103
,2014, 'Retinoic acid is required for the generation of protective appendiceal regulatory T cells', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 29, pp. 20 - 20, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000343863000041&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2014, 'Fruit-derived phenolic compounds and pancreatic cancer: Perspectives from Australian native fruits', Journal of Ethnopharmacology, 152, pp. 227 - 242, http://dx.doi.org/10.1016/j.jep.2013.12.023
,