By Professor Stuart Graham Tangye

Conference Abstracts

Tangye S, 2021, 'Somatic reversion of pathogenic DOCK8 variants alters lymphocyte differentiation and function to effectively cure DOCK8 deficiency', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Vol. 41, pp. S16 - S16, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000639851600023&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Humphrey A; Tangye S; Preece K, 2020, 'IRAK4 Deficiency Presenting with Severe Viral Infections and Recurrent Kingella Kingae Sepsis', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CO, Denver, Vol. 40, pp. S74 - S75, presented at Annual Meeting of the Clinical-Immunology-Society (CIS) / Immune Deficiency and Dysregulation North American Conference, CO, Denver, 02 April 2020 - 05 April 2020, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000540191100101&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Masle-Farquhar E; Payne K; Jackson K; Rao G; Singh M; El-Eryani G; Brink R; Tangye S; Reed J; Goodnow C, 2019, 'The effects of germline STAT3-activating mutations from autoimmunity and lymphoid malignancy on mouse and human T cell development and function', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY, PEOPLES R CHINA, Beijing, Vol. 49, pp. 901 - 901, presented at 17th International Congress of Immunology of the International-Union-of-Immunological-Societies (IUIS), PEOPLES R CHINA, Beijing, 19 October 2019 - 23 October 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000490026902546&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Yap JY; Gloss B; Batten M; Hsu P; Berglund L; Polizzotto M; Kirk E; Deenick E; Ma C; Tangye S; Phan TG, 2019, 'EVEROLIMUS-INDUCED REMISSION OF KAPOSI'S SARCOMA SECONDARY TO CRYPTIC CTLA4 SPLICING AND HAPLOINSUFFICIENCY', in INTERNAL MEDICINE JOURNAL, WILEY, Vol. 49, pp. 35 - 36, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000488891400106&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Swamy S; Tangye S; Gray P, 2019, 'THE UNWANTED SUPERPOWER', in INTERNAL MEDICINE JOURNAL, WILEY, Vol. 49, pp. 41 - 41, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000488891400125&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Tri GP; Tangye S; Wong M; Gray P; Batten M; Goodnow C; Burnett L, 2018, 'CLINICAL IMPACT OF WHOLE GENOME SEQUENCING ON THE DIAGNOSIS AND MANAGEMENT OF PATIENTS WITH PRIMARY IMMUNODEFICIENCY DISEASES - THE CLINICAL IMMUNOGENOMICS RESEARCH CONSORTIUM AUSTRALIA (CIRCA) EXPERIENCE', in INTERNAL MEDICINE JOURNAL, WILEY, Vol. 48, pp. 29 - 29, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000449673000079&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Jing H; Abolhassani H; Edwards ESJ; Ikinciogullari KA; Borte S; Buggert M; Du L; Lennikov M; Romano R; Caridha R; Bade S; Zhang Y; Frederiksen J; Fang M; Bal SK; Haskologlu S; Dogu F; Tacyildiz N; Matthews HF; McElwee JJ; Gostick E; Price DA; Palendira U; Aghamohammadi A; Boisson B; Rezaei N; Karlsson A; Lenardo MJ; Casanova J-L; Hammarstrom L; Tangye SG; Pan-Hammarstrom Q; Su HC, 2017, 'COMBINED IMMUNODEFICIENCY AND EPSTEIN-BARR VIRUS-INDUCED B CELL MALIGNANCY IN HUMANS WITH INHERITED CD70 DEFICIENCY', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, WA, Seattle, Vol. 37, pp. 230 - 230, presented at CIS Annual Meeting on Immune Deficiency and Dysregulation North American, WA, Seattle, 23 March 2017 - 26 March 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000396924700093&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Nguyen A; Moran I; Tanaka M; Tangye S; Brink R; Phan T, 2016, 'Dynamic changes in gene regulatory networks control subcapsular sinus macrophage fate and function', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 430 - 430, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610401057&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Edwards ESJ; Cole T; Wong M; Uzel G; Tangye SG, 2016, 'Effect of gain-of-function mutations in PI3 kinase p110d on the phenotype and function of EBV-specific CD8(+) T-cells', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 980 - 981, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610402365&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Woon H; Braun A; Li J; Smith C; Edwards J; Sierro F; Feng C; Khanna R; Elliot M; Tangye S; Rickinson A; Gebhardt T; Britton W; Palendira M, 2016, 'IL-15 and TGF-beta promote the selective retention of virus-specific resident memory T cells in human lymphoid organs', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 57 - 57, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400113&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Vijayan D; Redzwan MN; Avery D; Wirasinha R; Brink R; Walters G; Adelstein S; Kobayashi M; Gray P; Elliott M; King C; Vinuesa C; Ghilardi N; Ma C; Tangye S; Batten M, 2016, 'IL-27 directly influences germinal center B cell development via STAT1', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 1082 - 1082, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610402571&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Jandl C; Liu SM; Nieto FDCP; Warren J; Hughes WE; Vogelzang A; Webster K; Craig M; Uzel G; Tangye S; Dent A; Vinuesa C; Sprent J; King C, 2016, 'Interleukin-21 limits regulatory T cell populations by modulating responsiveness to Interleukin-2', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 102 - 102, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400203&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Tangye S, 2016, 'Intrinsic functional defects in human lymphocytes: insights into disease pathogenesis of primary immunodeficiencies', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 1000 - 1000, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610402407&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Suan D; Krautler N; Maag J; Butt D; Wood K; Hermes J; Priestley D; Statham A; Elliott M; Marcel D; Basten A; Tangye S; Brink R, 2016, 'Memory B cells develop from low-affinity clones in the germinal center light zone and are identified by CCR6 expression in mice and humans', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 1132 - 1133, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610402674&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Pelham SJ; Lenthall H; Deenick EK; Tangye SG, 2016, 'Mutations underlying autosomal dominant hyper-IgE syndrome impair distinct stages of STAT3 signaling', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 139 - 140, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400280&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Martinez-Barricarte R; Kong X-F; Kennedy J; Lazarov T; Deenick E; Ma C; Mele F; Trouillet C; Bousfiha A; Aytekin C; Picard C; Salem S; Langlais D; Lasseau T; Migaud M; Abel L; Boisson-Dupuis S; Hambleton S; B S; Geissmann F; Tangye S; Sallusto F; Bustamante J; Gros P; Casanova J-L, 2016, 'Mycobacterial disease and myeloid dendritic cells defects in patients with SPPL2a deficiency', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 777 - 778, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610401757&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Butt D; Chan T; Bourne K; Hermes J; Strasser A; Tangye S; Phan T; Rao VK; Brink R, 2016, 'Rogue germinal center B cells: unconventional lymphocytes released by FAS inactivation that drive IgE and autoantibody production', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 25 - 26, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400052&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Kane A; Lau A; Brink R; Tangye S; Deenick E, 2016, 'STAT3 is a critical B-cell intrinsic regulator of functional antibody responses and IgE production', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 849 - 849, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610402097&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Pillay BA; Ma CS; Casanova JL; Uzel G; Tangye SG, 2016, 'Using immunodeficiency patient cells in in vitro cultures to provide insight into T-helper cell differentiation', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 988 - 989, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610402382&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Tangye SG, 2016, 'DEFECTS IN HUMAN B-CELL DEVELOPMENT AND DIFFERENTIATION DUE TO DISEASE-CAUSING MUTATIONS IN THE PI3K PATHWAY', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Boston, MA, Vol. 36, pp. 298 - 299, presented at CIS Annual Meeting on Immune Deficiency and Dysregulation North American Conference, Boston, MA, 14 April 2016 - 17 April 2016, http://dx.doi.org/10.1007/s10875-016-0237-x

Martinez-Barricarte R; Aytekin C; Markle J; Kong X-F; Fleckenstein B; Tangye SG; van de Vosse E; Boisson-Dupuis S; Bustamante J; Casanova J-L, 2016, 'INHERITED IL-12R beta 2 DEFICIENCY CAUSES MYCOBACTERIAL SUSCEPTIBILITY', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, MA, Boston, Vol. 36, pp. 270 - 270, presented at CIS Annual Meeting on Immune Deficiency and Dysregulation North American Conference, MA, Boston, 14 April 2016 - 17 April 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000372165300095&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Bosch B; Dockx S; Tangye SG; Meyts I; Moens L, 2016, 'IPEX ... ARE ALL FEMALE CARRIERS HEALTHY?', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, MA, Boston, Vol. 36, pp. 252 - 252, presented at CIS Annual Meeting on Immune Deficiency and Dysregulation North American Conference, MA, Boston, 14 April 2016 - 17 April 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000372165300050&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Markle J; Okada S; Deenick E; Mele F; Averbuch D; Lagos M; Gonzalez M; Alzahrani M; Soudais C; Henderson L; Deswarte C; Jabot-Hanin F; Martinez-Barricarte R; Itan Y; Boisson B; Cooper A; Picard C; Abel L; Notarangelo L; Boisson-Dupuis S; Puel A; Sallusto F; Bustamante J; Tangye S; Casanova J-L, 2015, 'Impairment of IL-17A/F Immunity to Candida and IFN-g Immunity to Mycobacterium in Patients with RORC Deficiency', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, ARGENTINA, Buenos Aires, Vol. 35, pp. S13 - S14, presented at 4th Meeting of the Latin-American-Society-for-Immunodeficiencies (LASID), ARGENTINA, Buenos Aires, 18 November 2015 - 21 November 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000363977700030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Williams KW; Edwards E; Stoddard JL; Martinez B; Chen CC; Agharahimi A; Hussey AA; Niemala JE; Holland SM; Tangye SG; Uzel G, 2015, 'PRELIMINARY DATA FOR mTOR INHIBITOR TREATMENT IN PATIENTS WITH OF GAIN-OF-FUNCTION MUTATIONS IN PIK3CD', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, TX, Houston, Vol. 35, pp. 314 - 315, presented at North American Annual Conference of the Clinical-Immunology-Society (CIS) on Immune Deficiency and Dysregulation, TX, Houston, 09 April 2015 - 12 April 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000351510200043&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Gray P; Walsh C; Zhu Y; Elakis G; Mullan G; Lo W; Lee E; Cowley M; Dinger M; Buckley M; Ziegler J; Tangye S; Roscioli T, 2014, 'Extrapulmonary Non-Tuberculous Mycobacterial Infection in a Child with Autosomal Dominant Hyper IgE Syndrome', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, Vol. 34, pp. S499 - S500, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100775&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Frith K; O'Brien T; Tangye S; Sutton R; Ziegler J; Gray P, 2014, 'XLP-Associated Cerebral Vasculitis Successfully Treated with Bone Marrow Transplant', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Prague, CZECH REPUBLIC, Vol. 34, pp. S241 - S241, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, Prague, CZECH REPUBLIC, 29 October 2014 - 01 November 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100212&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

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