By Scientia Professor Anthony D Kelleher

Journal articles

Madhavi V; Ana-Sosa-Batiz FE; Jegaskanda S; Center RJ; Winnall WR; Parsons MS; Ananworanich J; Cooper DA; Kelleher AD; Hsu D; Pett S; Stratov I; Kramski M; Kent SJ, 2015, 'Antibody-dependent effector functions against HIV decline in subjects receiving antiretroviral therapy', Journal of Infectious Diseases, 211, pp. 529 - 538, http://dx.doi.org/10.1093/infdis/jiu486

Fernandez CS; Amarasena T; Kelleher AD; Rossjohn J; Mccluskey J; Godfrey DI; Kent SJ, 2015, 'MAIT cells are depleted early but retain functional cytokine expression in HIV infection', Immunology and Cell Biology, 93, pp. 177 - 188, http://dx.doi.org/10.1038/icb.2014.91

Boyd MA; Moore CL; Molina JM; Wood R; Madero JS; Wolff M; Ruxrungtham K; Losso M; Renjifo B; Teppler H; Kelleher AD; Amin J; Emery S; Cooper DA, 2015, 'Baseline HIV-1 resistance, virological outcomes, and emergent resistance in the SECOND-LINE trial: An exploratory analysis', The Lancet HIV, 2, pp. e42 - e51, http://dx.doi.org/10.1016/S2352-3018(14)00061-7

Tong WWY; Shepherd K; Garland S; Meagher A; Templeton DJ; Fairley CK; Jin F; Poynten IM; Zaunders J; Hillman RJ; Grulich AE; Kelleher AD; Carr A; Acraman B; Fraissard E; Law C; McGrath P; Mellor R; Norris R; O'Dwyer M; Seeds D; Thompson K; Varma R; Adams M; Biro C; Cornall A; Crampton L; Ekman D; Ellard J; Farnsworth A; Feeney L; Howard K; Hyne S; Law M; Machalek D; McCaffery K; McDonald R; Pendlebury S; Petoumenos K; Phillips S; Prestage G; Richards A; Roberts J; Schema L; Segelov E; Tabrizi S; Thurloe J; Bailey M; Cunningham P; Fsadni B; Grassi K; Ip S; Lograsso M; McBride K; Merlin K; Munier M-L; Piperias M; Xu Y, 2015, 'Human Papillomavirus 16-Specific T-Cell Responses and Spontaneous Regression of Anal High-Grade Squamous Intraepithelial Lesions', Journal of Infectious Diseases, 211, pp. 405 - 415, http://dx.doi.org/10.1093/infdis/jiu461

Suzuki K; Ahlenstiel C; Marks K; Kelleher AD, 2015, 'Promoter targeting RNAs: Unexpected contributors to the control of HIV-1 transcription', Molecular Therapy Nucleic Acids, 4, pp. e222, http://dx.doi.org/10.1038/mtna.2014.67

Zaunders J; Jing J; Leipold M; Maecker H; Kelleher AD; Koch I, 2015, 'Computationally efficient multidimensional analysis of complex flow cytometry data using second order polynomial histograms', Cytometry Part A, 89, pp. 44 - 58, http://dx.doi.org/10.1002/cyto.a.22704

Ahlenstiel CL; Suzuki K; Marks K; Symonds GP; Kelleher AD, 2015, 'Controlling HIV-1: Non-coding RNA gene therapy approaches to a functional cure', Frontiers in Immunology, 6, pp. 474, http://dx.doi.org/10.3389/fimmu.2015.00474

Colineau L; Rouers A; Yamamoto T; Xu Y; Urrutia A; Pham HP; Cardinaud S; Samri A; Dorgham K; Coulon PG; Cheynier R; Hosmalin A; Oksenhendler E; Six A; Kelleher AD; Zaunders J; Koup RA; Autran B; Moris A; Graff-Dubois S, 2015, 'HIV-infected spleens present altered follicular helper T cell (Tfh) subsets and skewed B cell maturation', PLoS ONE, 10, pp. e0140978, http://dx.doi.org/10.1371/journal.pone.0140978

Phetsouphanh C; Kelleher AD, 2015, 'The role of PKC-θ in CD4+ T cells and HIV infection: To the nucleus and back again', Frontiers in Immunology, 6, pp. 391, http://dx.doi.org/10.3389/fimmu.2015.00391

Koelsch KK; Hey-Cunningham WJ; Sasson SC; Pearson C; Bailey M; Marks KH; Hiener BM; Palmer S; Zaunders JJ; Post JJ; Milliken ST; Kelleher AD; Cooper DA; Xu Y, 2015, 'Allogeneic bone marrow transplantation in two HIV-1 infected patients shows no detectable HIV-1 RNA or DNA, and a profound reduction in HIV-1 antibodies', Pathology, 47, pp. S55 - S55, http://dx.doi.org/10.1097/01.pat.0000461459.26902.eb

Tong WWY; Turville S; Roberts J; Zaunders J; Jin F; Poynten IM; Hillman RJ; Grulich AE; Kelleher AD; Carr A, 2015, 'P10.10 T-cells in the anal mucosa of men with high-grade squamous intraepithelial lesions', Sexually Transmitted Infections, 91, pp. A168.2 - A168, http://dx.doi.org/10.1136/sextrans-2015-052270.438

Méndez C; Ahlenstiel CL; Kelleher AD, 2015, 'Post-transcriptional gene silencing, transcriptional gene silencing and human immunodeficiency virus.', World Journal of Virology, 4, pp. 219 - 244, http://dx.doi.org/10.5501/wjv.v4.i3.219

Sasson SC; McGill K; Wienholt L; Carr A; Brown D; Kelleher AD; Breit SN; Sewell WA, 2015, 'Retrospective audit of the freeliteTM serum free light chain (SFLC) assay: testing patterns, concordance with serum and urine electrophoresis/immunofixation and correlation with the N latex FLC assay', Pathology, 47, pp. S94 - S94, http://dx.doi.org/10.1097/01.pat.0000461601.28805.d5

Bavinton BR; Jin F; Prestage G; Zablotska I; Koelsch KK; Phanuphak N; Grinsztejn B; Cooper DA; Fairley C; Kelleher A; Triffitt K; Grulich AE; Templeton D; Emery S, 2014, 'The Opposites Attract Study of viral load, HIV treatment and HIV transmission in serodiscordant homosexual male couples: Design and methods', BMC Public Health, 14, pp. 917, http://dx.doi.org/10.1186/1471-2458-14-917

Sasson S; Smith S; Sewell WA; Morey A; Danta M; Emmett L; Kelleher AD; Fay K; Phan T, 2014, 'MONOCLONAL B-CELL POPULATION OF INDETERMINANT MALIGNANT POTENTIAL IN THE SETTING OF ATYPICAL CVID ASSOCIATED WITH LYMPHADENOPATHY AND SPLENOMEGALY', INTERNAL MEDICINE JOURNAL, 44, pp. 33 - 33, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000342722800109&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Martin E; Carlson JM; Le AQ; Chopera DR; McGovern R; Rahman MA; Ng C; Jessen H; Kelleher AD; Markowitz M; Allen TM; Milloy MJ; Carrington M; Wainberg MA; Brumme ZL, 2014, 'Early immune adaptation in HIV-1 revealed by population-level approaches', Retrovirology, 11, pp. 64, http://dx.doi.org/10.1186/s12977-014-0064-1

Sasson SC; Kelleher AD, 2014, 'Site-specific host gene modification by zinc finger nucleases: pointing the way to drug free control of HIV-1?', Clinical and Translational Immunology, 3, pp. e19, http://dx.doi.org/10.1038/cti.2014.12

Achhra AC; Boyd MA; Law MG; Matthews GV; Kelleher AD; Cooper DA; Han A, 2014, 'Moving away from ritonavir, abacavir, tenofovir, and efavirenz (RATE) - Agents that concern prescribers and patients: A feasibility study and call for a trial', PLoS ONE, 9, pp. e99530, http://dx.doi.org/10.1371/journal.pone.0099530

Kelleher AD, 2014, 'Promoter targeted small RNAs: stabilising viral reservoirs', MICROBIOLOGY AUSTRALIA, 35, pp. 103 - 104, http://dx.doi.org/10.1071/MA14033

Haskelberg H; Cordery DV; Amin J; Kelleher AD; Cooper DA; Emery S; Post J, 2014, 'HLA Alleles association with changes in bone mineral density in HIV-1-infected adults changing treatment to tenofovir-emtricitabine or abacavir-lamivudine', PLoS ONE, 9, pp. e93333, http://dx.doi.org/10.1371/journal.pone.0093333

Tong WWY; Hillman RJ; Kelleher AD; Grulich AE; Carr A, 2014, 'Anal intraepithelial neoplasia and squamous cell carcinoma in HIV-infected adults', HIV Medicine, 15, pp. 65 - 76, http://dx.doi.org/10.1111/hiv.12080

Amin J; Law MG; Puls R; Kelleher A; Cooper DA; Emery S; Han A, 2014, 'Comparison of central and local HIV-1 RNA quantification from two international clinical trials', AIDS, 28, pp. 2480 - 2483, http://dx.doi.org/10.1097/QAD.0000000000000461

Amin J; Becker S; Belloso W; Boffito M; Cooper D; Crabtree-Ramirez B; Duncombe C; Emery S; Foulkes S; Hill A; Jessen H; Kumar S; Lee MP; Losso M; Nwizu C; Phanuphak P; Ripin D; Read T; Rooney J; Schaffer K; Shahar E; Winston A; Wolff M; Young B; Abela C; Boyd M; Carey D; Clarke A; Courtney-Vega K; Dazo C; Delfino M; Donaldson A; Espinosa N; Johannesen T; Kaew-On P; Lin E; Moricz A; Taylor J; Phanupak P; Puls RL; Pussadee K; Sutheerasak P; Tomkins L; Ubolyam S; Shah Bin Raja Azwa RI; Bissio E; Calanni L; Casiro A; Chetchotisakd P; Contarelli J; Doong N; Elliott J; Gazzard B; Kelly M; Del Carmen Luna N; Lupo S; Messina OG; Mohapi L; Moore R; Nolan D; Orrell C; Perez C; Pett S; Rockstroh J; Supparatpinyo K; Smith D; Villanueva JA; Vlahakis E; Kelleher T; Cunningham P; Merlin K; Yeung J; Shaik A; Fsadni B; Carrera A; Lograsso M; Gulick R; Crabtree-Ramiraz B; Winston E; Dunn D; Dolan M; Cooper D; Kelleher A, 2014, 'Efficacy of 400 mg efavirenz versus standard 600 mg dose in HIV-infected, antiretroviral-naive adults (ENCORE1): A randomised, double-blind, placebo-controlled, non-inferiority trial', The Lancet, 383, pp. 1474 - 1482, http://dx.doi.org/10.1016/S0140-6736(13)62187-X

Streeck H; Lu R; Beckwith N; Milazzo M; Liu M; Routy JP; Little S; Jessen H; Kelleher AD; Hecht F; Sekaly RP; Alter G; Heckerman D; Carrington M; Rosenberg ES; Altfeldc M, 2014, 'Emergence of individual HIV-specific CD8 T cell responses during primary HIV-1 infection can determine long-term disease outcome', Journal of Virology, 88, pp. 12793 - 12801, http://dx.doi.org/10.1128/JVI.02016-14

Pham QD; Wilson DP; Law MG; Kelleher AD; Zhang L; Han A, 2014, 'Global burden of transmitted HIV drug resistance and HIV-exposure categories: A systematic review and meta-analysis', AIDS, 28, pp. 2751 - 2762, http://dx.doi.org/10.1097/QAD.0000000000000494

Murray JM; Zaunders JJ; McBride KL; Xu Y; Bailey M; Suzuki K; Cooper DA; Emery S; Kelleher AD; Koelsch KK, 2014, 'HIV DNA subspecies persist in both activated and resting memory CD4⁺ T cells during antiretroviral therapy', Journal of Virology, 88, pp. 3516 - 3526, http://dx.doi.org/10.1128/JVI.03331-13

Williams JP; Hurst J; Stöhr W; Robinson N; Brown H; Fisher M; Kinloch S; Cooper D; Schechter M; Tambussi G; Fidler S; Carrington M; Babiker A; Weber J; Koelsch KK; Kelleher AD; Phillips RE; Frater J, 2014, 'HIV-1 DNA predicts disease progression and post-treatment virological control', eLife, 3, pp. e03821, http://dx.doi.org/10.7554/eLife.03821

Ana-Sosa-Batiz F; Johnston APR; Liu H; Center RJ; Rerks-Ngarm S; Pitisuttithum P; Nitayaphan S; Kaewkungwal J; Kim JH; Michael NL; Kelleher AD; Stratov I; Kent SJ; Kramski M, 2014, 'HIV-specific antibody-dependent phagocytosis matures during HIV infection', Immunology and Cell Biology, 92, pp. 679 - 687, http://dx.doi.org/10.1038/icb.2014.42

Seddiki N; Cook L; Hsu DC; Phetsouphanh C; Brown K; Xu Y; Kerr SJ; Cooper DA; Munier CML; Pett S; Ananworanich J; Zaunders J; Kelleher AD, 2014, 'Human antigen-specific CD4⁺CD25⁺CD134⁺CD39⁺ T cells are enriched for regulatory T cells and comprise a substantial proportion of recall responses', European Journal of Immunology, 44, pp. 1644 - 1661, http://dx.doi.org/10.1002/eji.201344102

Kuang XT; Li X; Anmole G; Mwimanzi P; Shahid A; Le AQ; Chong L; Qian H; Miura T; Markle T; Baraki B; Connick E; Daar ES; Jessen H; Kelleher AD; Little S; Markowitz M; Pereyra F; Rosenberg ES; Walker BD; Ueno T; Brumme ZL; Brockman MA; Walker B, 2014, 'Impaired Nef function is associated with early control of HIV-1 viremia', Journal of Virology, 88, pp. 10200 - 10213, http://dx.doi.org/10.1128/JVI.01334-14

Hsu DC; Kerr SJ; Thongpaeng P; Iampornsin T; Pett SL; Zaunders JJ; Avihingsanon A; Ubolyam S; Ananworanich J; Kelleher AD; Cooper DA, 2014, 'Incomplete restoration of Mycobacterium tuberculosis-specific-CD4 T cell responses despite antiretroviral therapy', Journal of Infection, 68, pp. 344 - 354, http://dx.doi.org/10.1016/j.jinf.2013.11.016

Swaminathan S; Kelleher AD, 2014, 'MicroRNA modulation of key targets associated with T cell exhaustion in HIV-1 infection', Current Opinion in HIV and AIDS, 9, pp. 464 - 471, http://dx.doi.org/10.1097/COH.0000000000000089

Fernandez CS; Kelleher AD; Finlayson R; Godfrey DI; Kent SJ, 2014, 'NKT cell depletion in humans during early HIV infection', Immunology and Cell Biology, 92, pp. 578 - 590, http://dx.doi.org/10.1038/icb.2014.25

Phetsouphanh C; Xu Y; Bailey M; Pett S; Zaunders J; Seddiki N; Kelleher AD, 2014, 'Ratios of effector to central memory antigen-specific CD4 + T cells vary with antigen exposure in HIV+ patients', Immunology and Cell Biology, 92, pp. 384 - 388, http://dx.doi.org/10.1038/icb.2013.101

Pantazis N; Porter K; Costagliola D; De Luca A; Ghosn J; Guiguet M; Johnson AM; Kelleher AD; Morrison C; Thiebaut R; Wittkop L; Touloumi G, 2014, 'Temporal trends in prognostic markers of HIV-1 virulence and transmissibility: An observational cohort study', The Lancet HIV, 1, pp. e119 - e126, http://dx.doi.org/10.1016/S2352-3018(14)00002-2

Kelleher AD, 2014, 'Promoter targeted small RNAs: stabilising viral reservoirs', Microbiology Australia, 10, pp. 1071

Murray JM; Zaunders JJ; Koelsch KK; Natarajan V; Badralmaa Y; McBride K; Carrera A; Cooper DA; Emery S; Kelleher AD, 2013, 'Short communication: HIV blips while on antiretroviral therapy can indicate consistently detectable viral levels due to assay underreporting', AIDS Research and Human Retroviruses, 29, pp. 1621 - 1625, http://dx.doi.org/10.1089/aid.2013.0132

Vaidya SA; Streeck H; Beckwith N; Ghebremichael M; Pereyra F; Kwon DS; Addo MM; Rychert J; Routy JP; Jessen H; Kelleher AD; Hecht F; Sekaly RP; Carrington M; Walker BD; Allen TM; Rosenberg ES; Altfeld M, 2013, 'Temporal effect of HLA-B*57 on viral control during primary HIV-1 infection', Retrovirology, 10, http://dx.doi.org/10.1186/1742-4690-10-139

Hsu DC; Kerr SJ; Iampornsin T; Pett SL; Avihingsanon A; Thongpaeng P; Zaunders JJ; Ubolyam S; Ananworanich J; Kelleher AD; Cooper DA, 2013, 'Restoration of CMV-Specific-CD4 T Cells with ART Occurs Early and Is Greater in Those with More Advanced Immunodeficiency', PLoS ONE, 8, http://dx.doi.org/10.1371/journal.pone.0077479

Phetsouphanh C; Xu Y; Amin J; Seddiki N; Procopio F; Sekaly RP; Zaunders JJ; Kelleher AD, 2013, 'Characterization of Transcription Factor Phenotypes within Antigen-Specific CD4+ T Cells Using Qualitative Multiplex Single-Cell RT-PCR', PLoS ONE, 8, http://dx.doi.org/10.1371/journal.pone.0074946

McBride K; Xu Y; Bailey M; Seddiki N; Suzuki K; Murray JM; Gao Y; Yan C; Cooper DA; Kelleher AD; Koelsch KK; Zaunders J, 2013, 'The majority of HIV type 1 DNA in circulating CD4⁺ T lymphocytes is present in non-gut-homing resting memory CD4⁺ T cells', AIDS Research and Human Retroviruses, 29, pp. 1330 - 1339, http://dx.doi.org/10.1089/aid.2012.0351

Kent SJ; Reece JC; Petravic J; Martyushev A; Kramski M; De Rose R; Cooper DA; Kelleher AD; Emery S; Cameron PU; Lewin SR; Davenport MP, 2013, 'The search for an HIV cure: Tackling latent infection', The Lancet Infectious Diseases, 13, pp. 614 - 621, http://dx.doi.org/10.1016/S1473-3099(13)70043-4

French MA; Center RJ; Wilson KM; Fleyfel I; Fernandez S; Schorcht A; Stratov I; Kramski M; Kent SJ; Kelleher AD, 2013, 'Isotype-switched immunoglobulin G antibodies to HIV Gag proteins may provide alternative or additional immune responses to 'protective' human leukocyte antigen-B alleles in HIV controllers', AIDS, 27, pp. 519 - 528, http://dx.doi.org/10.1097/QAD.0b013e32835cb720

Suzuki K; Hattori S; Marks K; Ahlenstiel C; Maeda Y; Ishida T; Millington M; Boyd M; Symonds G; Cooper DA; Okada S; Kelleher AD, 2013, 'Promoter Targeting shRNA Suppresses HIV-1 Infection In vivo Through Transcriptional Gene Silencing', Molecular Therapy Nucleic Acids, 2, pp. e137, http://dx.doi.org/10.1038/mtna.2013.64

Tu E; Swenson LC; Land S; Pett S; Emery S; Marks K; Kelleher AD; Kaye S; Kaiser R; Schuelter E; Harrigan R, 2013, 'Results of external quality assessment for proviral DNA testing of HIV tropism in the Maraviroc switch collaborative study', Journal of Clinical Microbiology, 51, pp. 2063 - 2071, http://dx.doi.org/10.1128/JCM.00510-13

Mee Ling Munier C; Kelleher AD; Kent SJ; De Rose R, 2013, 'The role of T cell immunity in HIV-1 infection', Current Opinion in Virology, 3, pp. 438 - 446, http://dx.doi.org/10.1016/j.coviro.2013.05.009

Gilmore JB; Kelleher AD; Cooper DA; Murray JM, 2013, 'Explaining the determinants of first phase HIV decay dynamics through the effects of stage-dependent drug action', PLoS Computational Biology, 9, pp. e1002971 (11pp), http://dx.doi.org/10.1371/journal.pcbi.1002971

Swaminathan S; Murray DD; Kelleher AD, 2013, 'Mirnas and HIV: Unforeseen Determinants Of Host-Pathogen Interaction', Immunological Reviews, 254, pp. 265 - 280, http://dx.doi.org/10.1111/imr.12077Document

Porter K; Ewings FM; Ramjee G; Cooper DA; Fisher M; Schechter MT; Tambussi G; Kinloch-De Loes S; Miro J; Kelleher AD; Mcclure MO; Gabriel M; Phillips R; Weber J; Babiker AG, 2013, 'Short-course antiretroviral therapy in primary HIV infection', New England Journal of Medicine, 368, pp. 207 - 217, http://dx.doi.org/10.1056/NEJMoa1110039

Xu Y; Weatherall CJ; Bailey MR; Alcantara S; De Rose R; Estaquier J; Wilson KM; Suzuki K; Corbeil J; Cooper DA; Kent SJ; Kelleher AD; Zaunders J, 2013, 'Simian immunodeficiency virus infects follicular helper CD4 T cells in lymphoid tissues during pathogenic infection of pigtail macaques', Journal of Virology, 87, pp. 3760 - 3773, http://dx.doi.org/10.1128/JVI.02497-12

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