By Scientia Professor Anthony D Kelleher

Journal articles

Murray JM; Kelleher ; Cooper DA, 2011, 'Timing of the components of the HIV life cycle in productively infected CD4+ T cells in a population of HIV-infected individuals', Journal of Virology, 85, pp. 10798 - 10805, http://dx.doi.org/10.1128/JVI.05095-11

Suzuki K; Ishida T; Yamagishi M; Ahlenstiel C; Swaminathan S; Marks K; Murray D; McCartney EM; Beard MR; Alexander M; Purcell DF; Cooper DA; Watanabe T; Kelleher AD, 2011, 'Transcriptional gene silencing of HIV-1 through promoter targeted RNA is highly specific.', RNA biology, 8, pp. 1035 - 1046

Swaminathan S; Hood CL; Suzuki K; Kelleher AD, 2010, 'RNA duplexes in transcriptional regulation', Biomolecular Concepts, 1, pp. 285 - 296, http://dx.doi.org/10.1515/bmc.2010.021

French MA; Tanaskovic S; Law MG; Lim A; Fernandez S; Ward LD; Kelleher AD; Emery S, 2010, 'Vaccine-induced IgG2 anti-HIV p24 is associated with control of HIV in patients with a 'high-affinity' FcγRIIa genotype', AIDS, 24, pp. 1983 - 1990, http://dx.doi.org/10.1097/QAD.0b013e32833c1ce0

Pett SL; Zaunders J; Bailey M; Murray JM; Macrae K; Emery S; Cooper DA; Kelleher AD, 2010, 'A novel Chemokine-Receptor-5 (CCR5) blocker, SCH532706, has differential effects on CCR5+CD4+ and CCR5+CD8+ T cell numbers in chronic HIV infection', AIDS Research and Human Retroviruses, 26, pp. 653 - 661, http://dx.doi.org/10.1089/aid.2009.0278

Pett SL; Emery S; Kelleher AD; Cooper DA, 2010, 'Antiretroviral agents: Focus on Maraviroc for the Treatment of HIV-1-Infected Adults', Clinical Medicine Insights: Therapeutics, 2, pp. CMT.S5420 - CMT.S5420, http://dx.doi.org/10.4137/cmt.s5420

Brockman M; Brumme ZL; Brumme CJ; Miura T; Sela J; Rosato PC; Kadie CM; Carlson JM; Markle TJ; Streeck H; Kelleher AD; Markowitz M; Jessen H; Rosenberg E; Atfeld M; Harrigan PR; Heckerman D; Walker BD; Allen TM, 2010, 'Early selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infection', Journal of Virology, 84, pp. 11937 - 11949

Arnott A; Jardine D; Wilson K; Gorry P; Merlin K; Grey PA; Law MG; Dax E; Kelleher AD; Smith DE; Mcphee D, 2010, 'High viral fitness during acute HIV-1 infection', PLoS One, 5, pp. e12631, http://dx.doi.org/10.1371/journal.pone.0012631

Miura T; Brumme ZL; Brockman MA; Rosato P; Sela J; Brumme CJ; Pereyra F; Kaufmann DE; Trocha A; Block BL; Daar ES; Connick E; Jessen H; Kelleher AD; Rosenberg E; Markowitz M; Schafer K; Vaida F; Iwamoto A; Little S; Walker BD, 2010, 'Impaired replication capacity of acute/early viruses in persons who become HIV controllers', Journal of Virology, 84, pp. 7581 - 7591

Koelsch KK; Xu Y; Bailey M; McBride K; Seddiki N; Suzuki K; Murray J; Cooper DA; Kelleher AD; Zaunders J, 2010, 'Most HIV DNA in PBMC is present in non‐gut homing, resting memory CD4+ T cells with a ß7‐CD38‐CD127 high phenotype', Journal of the International AIDS Society, 13, http://dx.doi.org/10.1186/1758-2652-13-s3-o2

Tong WW; McAllister J; White PA; Kelleher A; Carr A, 2010, 'Transmission of triple-class, drug resistant HIV-1 in Australia', Internal Medicine Journal, 40, pp. 657 - 661, http://dx.doi.org/10.1111/j.1445-5994.2010.02296.x

Venturi V; Chin HY; Asher TE; Ladell K; Scheinberg P; Bornstein E; Van Bockel D; Kelleher AD; Douek DC; Price DA; Davenport MP, 2009, 'TCR β-chain sharing in human CD8⁺ T cell responses to cytomegalovirus and EBV', Journal of Immunology, 181, pp. 7853 - 7862, http://dx.doi.org/10.4049/jimmunol.181.11.7853

Reddy SMR; Center RJ; Suzuki K; Gorry P; Kelleher A; Purcell DF, 2009, 'P12-01. Construction and characterization of recombinant envelope glycoproteins derived from HIV-1 pre-seroconversion strains as potential vaccine immunogens', Retrovirology, 6, http://dx.doi.org/10.1186/1742-4690-6-S3-P167

Reddy SMR; Center RJ; Suzuki K; Gorry P; Kelleher A; Purcell DF, 2009, 'Construction and characterization of recombinant envelope glycoproteins derived from HIV-1 pre-seroconversion strains as potential vaccine immunogens', RETROVIROLOGY, 6, http://dx.doi.org/10.1186/1742-4690-6-S3-P167

Swaminathan S; Zaunders J; Wilkinson J; Suzuki K; Kelleher AD, 2009, 'Does the presence of anti-HIV miRNAs in monocytes explain their resistance to HIV-1 infection?', Blood, 113, pp. 5029 - 5030, http://dx.doi.org/10.1182/blood-2009-01-196741

Munier CM; Zaunders J; Ip S; Cooper DA; Kelleher AD, 2009, 'A culture amplified multi-parametric intracellular cytokine assay (CAMP-ICC) for enhanced detection of antigen specific T-cell responses', Journal of Immunological Methods, 345, pp. 1 - 16

Byakwaga H; Murray JM; Petoumenos K; Kelleher AD; Law MG; Boyd MA; Emery S; Mallon PW; Cooper DA, 2009, 'Evolution of CD4+T cell count in HIV-1-infected adults receiving antiretroviral therapy with sustained long-term virological suppression', AIDS Research and Human Retroviruses, 25, pp. 569 - 576

Zaunders J; Munier ML; Seddiki N; Pett SL; Ip S; Bailey M; Xu Y; Brown KJ; Dyer W; Kim MS; De Rose R; Kent SJ; Jiang L; Breit SN; Emery S; Cunningham AL; Cooper DA; Kelleher AD, 2009, 'High levels of human antigen-specific CD4+ T cells in peripheral blood revealed by stimulated coexpression of CD25 and CD134 (OX40)', Journal of Immunology, 183, pp. 2827 - 2836, http://dx.doi.org/10.4049/jimmunol.0803548

Matthews PM; Leslie A; Katzourakis A; Crawford H; Payne R; Prendergast A; Power KA; Kelleher AD; Klenerman P; Carlson J; Heckerman D; Ndung''u T; Walker BD; Allen TM; Pybus O; Goulder PJ, 2009, 'HLA Footprints on human immunodeficiency virus tp 1 are associated with interclade polymorphisms and intraclade phylogenetic clustering', Journal of Virology, 83, pp. 4605 - 4615, http://dx.doi.org/10.1128/JVI.02017-08

Matthews PM; Leslie A; Katzourakis A; Crawford H; Payne R; Prendergast A; Power KA; Kelleher AD; Klenerman P; Carlson J; Heckerman D; Ndung''u T; Walker BD; Allen TM; Pybus O; Goulder PJ, 2009, 'HLA Footprints on Human Immunodeficiency Virus Type 1 Are Associated with Interclade Polymorphisms and Intraclade Phylogenetic Clustering', Journal of Virology, 83, pp. 4605 - 4615, http://jvi.asm.org/content/85/9/4635

Streeck H; Jolin J; Qi YC; Yassine-Diab B; Johnson ; Kwon D; Addo M; Brumme C; Routy J; Little S; Jessen H; Kelleher AD; Hecht FM; Sekaly R; Rosenberg E; Walker BD; Carrington M; Altfeld M, 2009, 'Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells', Journal of Virology, 83, pp. 7641 - 7648

Seddiki N; Sasson SC; Santner-Nanan B; Munier M; Van Bockel DJ; Ip S; Marriott D; Pett SL; Nanan R; Cooper DA; Zaunders J; Kelleher AD, 2009, 'Proliferation of weakly suppressive regulatory CD4+ T cells is associated with over-active CD4+ T-cell responses in HIV-positive patients with mycobacterial immune restoration disease', European Journal of Immunology, 39, pp. 391 - 403, http://dx.doi.org/10.1002/eji.200838630

Yamagishi M; Ishida T; Miyake A; Cooper DA; Kelleher AD; Suzuki K; Watanabe T, 2009, 'Retroviral delivery of promoter-targeted shRNA induces long-term silencing of HIV-1 transcription', Microbes and Infection, 11, pp. 500 - 508

Suzuki K; Kelleher AD, 2009, 'Transcriptional regulation by promoter targeted RNAs', Current Topics in Medicinal Chemistry, 9, pp. 1079 - 1087

Schneidewind A; Brumme Z; Brumme C; Power KA; Reyor L; O Sullivan K; Gladden A; Hempel U; Kuntzen T; Wang YE; Oniangue-Ndza C; Jessen H; Markowitz M; Rosenberg E; Sekaly R; Kelleher AD; Walker BD; Allen TM, 2009, 'Transmission and long-term stability of compensated CD8 escape mutations', Journal of Virology, 83, pp. 3993 - 3997

Weatherall CJ; Kelleher AD; Cooper DA, 2009, 'Trials and tribulations of HIV vaccines', Future Hiv Therapy, 3, pp. 145 - 160

Hamilton AR; Kelleher AD; Marriott D, 2009, 'Unusual association of diseases/symptoms: A case of severe visceral leishmaniasis resulting from travel to Greece', BMJ Case Reports, http://dx.doi.org/10.1136/bcr.06.2009.2036

Pantazis N; Touloumi G; Vanhems P; Gill J; Bucher HC; Porter K; CASCADE Collaboration , 2008, 'The effect of antiretroviral treatment of different durations in primary HIV infection.', AIDS, 22, pp. 2441 - 2450, http://dx.doi.org/10.1097/QAD.0b013e328319ea4e

Pett SL; Zaunders J; Bailey M; Cooper DA; MacRae K; Emery S; Kelleher A, 2008, 'Changes in CCR5+ cells and antigen-specific CD4+ T-cells during monotherapy with a CCR5 antagonist SCH532706 compared with combination therapy', Journal of the International AIDS Society, 11, http://dx.doi.org/10.1186/1758-2652-11-s1-p297

Jarrin I; Geskus R; Bhaskaran K; Prins M; Perez-Hoyos S; Muga R; Hernández-Aguado I; Meyer L; Porter K; Amo JD; Bucher H; Chêne G; Pillay D; Rosinska M; Sabin C; Touloumi G; del Amo J; Meyer L; Pillay D; Sabin C; Touloumi G; Porter K; Walker S; Babiker A; Darbyshire J; de Luca A; Fisher M; Goujard C; Muga R; Kaldor J; Kelleher T; Gelgor L; Ramacciotti T; Cooper D; Smith D; Gill J; Bruun Jørgensen L; Nielsen C; Pedersen C; Lutsar I; Dabis F; Thiebaut R; Masquelier B; Costagliola D; Vanhems P; Meyer L; Boufassa F; Hamouda O; Kucherer C; Pantazis N; Hatzakis A; Paraskevis D; Karafoulidou A; Rezza G; Dorrucci M; Longo B; Balotta C; van Asten L; van der Bij A; Coutinho R; Sannes M; Brubakk O; Eskild A; Bruun JN; Camacho R; Smolskaya T; Tor J; de Olalla PG; Caylà J; del Romero J; Belda J; Rickenbach M; Francioli P; Malyuta R; Brettle R; Delpech V; Lattimore S; Murphy G; Parry J; Gill N; Lee C; Porter K; Johnson A; Phillips A, 2008, 'Gender differences in HIV progression to AIDS and death in industrialized countries: Slower disease progression following HIV seroconversion in women', American Journal of Epidemiology, 168, pp. 532 - 540, http://dx.doi.org/10.1093/aje/kwn179

Bhaskaran K; Hamouda O; Sannes M; Boufassa F; Johnson AM; Lambert PC; Porter K; CASCADE Collaboration , 2008, 'Changes in the risk of death after HIV seroconversion compared with mortality in the general population.', JAMA, 300, pp. 51 - 59, http://dx.doi.org/10.1001/jama.300.1.51

Seddiki N; Kelleher AD, 2008, 'Regulatory T cells in HIV infection: Who's suppressing what?', Current Infectious Disease Reports, 10, pp. 252 - 258, http://dx.doi.org/10.1007/s11908-008-0041-8

Seddiki N; Kelleher AD, 2008, 'Regulatory T cells in HIV infection: Who's suppressing what?', Current HIV/AIDS Reports, 5, pp. 20 - 26, http://dx.doi.org/10.1007/s11904-008-0004-6

McElrath MJ; De Rosa SC; Moodie Z; Dubey S; Kierstead L; Janes H; Defawe OD; Carter DK; Hural J; Akondy R; Buchbinder SP; Robertson MN; Mehrotra DV; Self SG; Corey L; Shiver JW; Casimiro DR, 2008, 'HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis', The Lancet, 372, pp. 1894 - 1905, http://dx.doi.org/10.1016/S0140-6736(08)61592-5

Santner-Nanan B; Seddiki N; Zhu E; Quent V; Kelleher AD; Fazekas de St Groth B; Nanan R, 2008, 'Accelerated age-dependent transition of human regulatory T cells to effector memory phenotype', International Immunology, 20, pp. 375 - 383, http://dx.doi.org/10.1093/intimm/dxm151

Suzuki K; Juelich T; Lim H; Ishida T; Watanebe T; Cooper DA; Rao S; Kelleher AD, 2008, 'Closed chromatin architecture is induced by an RNA duplex targeting the HIV-1 promoter region', The Journal of Biological Chemistry, 283, pp. 23353 - 23363

Kelleher AD; Purcell D, 2008, 'Controlling HIV infection HIV co-receptor gets the finger', Immunology and Cell Biology, 86, pp. 641 - 642

Mallon PW; Sedwell R; Rogers GJ; Nolan D; Unemori P; Hoy JF; Samaras K; Kelleher AD; Emery S; Cooper DA; Carr AD, 2008, 'Effect of Rosiglitazone on Peroxisome Proliferator-Activated Receptor gamma Gene Expression in Human Adipose Tissue Is Limited by Antiretroviral Drug-Induced Mitochondrial Dysfunction', Journal of Infectious Diseases, 198, pp. 1794 - 1803

Chessman D; Kostenko L; Lethborg T; Purcell A; Williamson N; Chen Z; Kjer-Nielsen L; Mifsud N; Tait B; Holdsworth R; Almeida C; Nolan D; Macdonalds W; Archbold J; Kelleher AD; Marriott D; Mallal SA; Bharadwaj M; Rossjohn J; McCluskey J, 2008, 'Human leukocyte antigen class I-restricted activation of CD8(+) T cells provides the immunogenetic basis of a systemic drug hypersensitivity', Immunity, 28, pp. 822 - 832, http://dx.doi.org/10.1016/j.immuni.2008.04.020

Mason R; De Rose R; Seddiki N; Kelleher AD; Kent SJ, 2008, 'Low pre-infection levels and loss of central memory CD4+T cells may predict rapid progression in SIV-infected pigtail macaques', Virology, 381, pp. 11 - 15

Brumme Z; Brumme C; Carlson J; Streeck H; John M; Eichbaum Q; Block B; Baker B; Kadie C; Markowitz M; Jessen H; Kelleher AD; Rosenberg E; Kaldor JM; Yuki Y; Carrington M; Allen TM; Mallal SA; Altfeld M; Heckerman D; Walker BD, 2008, 'Marked epitope- and allele- specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection', Journal of Virology, 82, pp. 9216 - 9227

Lim H; Suzuki K; Cooper DA; Kelleher AD, 2008, 'Promoter-targeted siRNAs induce gene silencing of simian immunodeficiency virus (SIV) infection in vitro', Molecular Therapy, 16, pp. 565 - 570, http://dx.doi.org/10.1038/sj.mt.6300380

Seddiki N; Kelleher AD, 2008, 'Regulatory T cell abnormalities are associated with aberrant CD4+ T cell responses in patients with immune inflammatory syndrome (IRIS)', Clinical Immunology, 127, pp. S126 - S127, http://dx.doi.org/10.1016/j.ctim.2008.03.359

Burton C; Goodall R; Samri A; Autran B; Kelleher AD; Poli G; Pantaleo G; Gotch F; Imami N, 2008, 'Restoration of anti-tetanus toxoid responses in patients initiating highly active antiretroviral therapy with or without a boost immunization: an INITIO substudy', Clinical and Experimental Immunology, 152, pp. 252 - 257, http://dx.doi.org/10.1111/j.1365-2249.2008.03611.x

De Rose R; Mason RS; Loh L; Peut V; Smith MZ; Fernandez CS; Alcantara S; amarasena T; Reece J; Seddiki N; Kelleher AD; Zaunders J; Kent SJ, 2008, 'Safety, immunogenicity and efficacy of peptide-pulsed cellular immunotherapy in macaques.', Journal of Medical Primatology, 37, pp. 69 - 78

Streeck H; Van Bockel DJ; Kelleher AD, 2008, 'T-cell responses in primary HIV-1 infection. .', Current opinion in HIV & AIDS, 3, pp. 52 - 59

Venturi V; Chin HY; Asher TE; Ladell K; Scheinberg P; Bornstein E; van Bockel D; Kelleher AD; Douek DC; Price DA; Davenport MP, 2008, 'TCR beta-chain sharing in human CD8+ T cell responses to cytomegalovirus and EBV', Journal of Immunology, 181, pp. 7853 - 7862

Falster KA; Gelgor L; Shaik A; Zablotska Manos I; Prestage G; Grierson J; Thorpe R; Pitts M; Anderson JS; Chuah J; Mulhall BP; Petoumenos K; Kelleher AD; Law MG, 2008, 'Trends in antiretroviral treatment use and treatment response in three Australian states in the first decade of combination antiretroviral treatment', Sexual Health, 5, pp. 141 - 154

Lewin S; Murray JM; Solomon A; Wightman F; Cameron P; Purcell DJ; Zaunders J; Grey PA; Bloch M; Smith DE; Cooper DA; Kelleher AD, 2008, 'Virologic determinants of success after structured treatment interruptions in antiretrovirals in acute HIV-1 infection', JAIDS: Journal of Acquired Immune Deficiency Syndromes, 47, pp. 140 - 147

Zaunders J; Jing J; Leipold M; Maecker H; Kelleher AD; Koch I, 2007, 'Computationally efficient multidimensional analysis of complex flow cytometry data using second order polynomial histograms', Cytometry Part A, 89, pp. 44 - 58, http://dx.doi.org/10.1002/cyto.a.22704

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