By Scientia Professor Perminder Singh Sachdev

Journal articles

Dodich A; Panzavolta A; Funghi G; Meli C; Festari C; Chatzikostopoulos T; Chicherio C; Clarens F; de Oliveira FF; Filardi M; Ibanez A; Invernizzi L; Lebouvier T; Logroscino G; MacPherson SE; Manca R; Marra C; Matias-Guiu JA; Montembeault M; Papagno C; Pomati S; Possenti M; Piguet O; Sacco L; Schild AK; Sollberger M; Tábuas-Pereira M; Tsatali M; Tsolaki M; van den Berg E; Cappa SF; Bertoux M; Kumfor F; Van den Stock J; Boccardi M; Welsh-Bohmer KA; Cerami C; Bradshaw A; Oksengard AR; Pezzati R; Briales H; Weidner W; Zimmermann N; Strijkert F; Ruiu E; Dogdu C; Isernia S; Baglio F; Geurtsen G; Bartels C; Galli C; Fabbo A; Dori R; Wolski L; Morson S; Chrisman-Russell L; van der Waal HJ; Watermeyer T; Thompson J; Söntgerath M; Vestberg S; Schroeter M; Böhm F; Ahmed S; Piccoli T; Marano P; Herrero SR; Kounti F; Gallucci M; Meiberth D; Venneri A; Toraldo A; Shirk SD; Schöberl F; Sanchez P; Salmon DP; Sachdev P; Sensi S; Russo M; Rossi S; Ramakers I; Quaranta D; Plutino A; Papatriantafyllou J; Scarmeas N; Papageorgiou S; Ortiz ME; Novak P; Moraitou D; Monsch AU; Mitolo M; Menichelli A; Pigliautile M; Mecocci P; Matarrubia MF; Luzzi S; Luca A; Lima M; Levy R; Kukull WA, 2026, 'International consensus for the assessment of social cognition in neurocognitive disorders: framework definition and clinical recommendations of the SIGNATURE initiative', Alzheimer S Research and Therapy, 18, http://dx.doi.org/10.1186/s13195-025-01908-2

Reppermund S; Matison AP; Röhr S; Samtani S; Brodaty H; Soloveva MV; Li W; Molina MA; Schroers RD; Sachdev PS; Cerin E, 2026, 'Neighbourhood environments and depressive symptoms in later life', Journal of Affective Disorders, 413, http://dx.doi.org/10.1016/j.jad.2026.122259

Thurston MD; Mattingley JB; Lo JW; Sachdev PS; Desmond DW; Traykov L; Mehrabian S; Oestreich LKL, 2026, 'Trajectory classes of post-Stroke depression severity and their baseline predictors: A multi-cohort replication study', Journal of Affective Disorders, 411, http://dx.doi.org/10.1016/j.jad.2026.122017

Hayashi S; Jiang J; Song Y; Paradise M; Chan DKE; Wang D; Sachdev PS; Wen W, 2026, 'Enlarged Perivascular Spaces and Modifiable Vascular Risk Factors: Cross-Sectional and Longitudinal Analysis in the UK Biobank Cohort', American Journal of Geriatric Psychiatry, 34, pp. 1154 - 1166, http://dx.doi.org/10.1016/j.jagp.2025.11.016

Kalaria RN; Sachdev PS, 2026, 'VasCog-2-WSO Criteria for Vascular Cognitive Impairment and Dementia: A Revised Standard Put to the Test', Neurology, 107, pp. e218461, http://dx.doi.org/10.1212/WNL.0000000000218461

Vo-Eckerle TT; Gillespie NA; Christensen K; Finkel D; Kremen WS; Nygaard M; Sachdev PS; Thalamuthu A; Reynolds CA, 2026, 'Subjective sleep traits and cognition across mid- to late-adulthood: a cross-sectional study of gene-environment interplay', Sleep, 49, http://dx.doi.org/10.1093/sleep/zsag119

Lin K; Sachdev PS; Jiang J, 2026, 'The Associations of cerebral blood flow and white matter hyperintensities with tau and amyloid-beta across the Alzheimer's disease spectrum', Brain Imaging and Behavior, 20, http://dx.doi.org/10.1007/s11682-026-01187-x

McEwen K; Samtani S; Chen R; Crawford JD; Sachdev PS; Brodaty H; Numbers K, 2026, 'Incident dementia risk by frailty status and living arrangements in older adults', Journal of Frailty and Aging, 15, http://dx.doi.org/10.1016/j.tjfa.2026.100185

Zhang C; Vella AS; Chander RJ; Brodaty H; Sachdev PS; Numbers K, 2026, 'Combined Influence of Subjective Cognitive Complaints and Neuropsychiatric Symptoms on Cognitive Trajectories in Older Adults', Brain Sciences, 16, http://dx.doi.org/10.3390/brainsci16070693

Lipnicki DM; Vella AS; Castro-Costa E; Blay SL; Lima-Costa MF; Ritchie K; Rolandi E; Davin A; Rossi M; Kim KW; Han JW; Oh DJ; Ding D; Zhao Q; Zhou X; Chen YC; Chen JH; Sachdev PS, 2026, 'Disturbing dreams and dementia incidence across diverse cohort studies: A COSMIC collaboration study', Psychiatry and Clinical Neurosciences, 80, pp. 566 - 574, http://dx.doi.org/10.1111/pcn.70046

Giameos OE; Mellow ML; Karamacoska D; Davis A; Gardiner PA; Roccati E; Anstey KJ; Cherbuin N; Adsett JM; Wilson NA; Radford K; Lavrencic L; Sachdev PS; Reppermund S; Samtani S; Matison AP; Page ZA; Batterham PJ; Andrews SC; Bahar-Fuchs A; Lupton MK; Pipingas A; Withall A; Brown BM; Macpherson H; Keage HAD; Burton B; Vickers JC; Dunstan DW; Smith AE, 2026, 'Diversity and inclusivity in Australian dementia prevention research: A mixed methods review', Alzheimer S and Dementia Translational Research and Clinical Interventions, 12, pp. e70296, http://dx.doi.org/10.1002/trc2.70296

Powell A; Harvey L; Humburg P; CT Close J; Sachdev PS; Brodaty H, 2026, 'Health Care Outcomes Associated With Cognitive Super-Ageing', American Journal of Geriatric Psychiatry, 34, pp. 925 - 935, http://dx.doi.org/10.1016/j.jagp.2026.02.018

Pakpahan E; Guan Z; Siervo M; Muniz-Terrera G; Mohan D; Acosta D; Sosa AL; Acosta I; Llibre-Rodriguez JJ; Llibre-Guerra JJ; Prince M; Worrall A; Naheed A; Vella AS; Jiang J; Lipnicki DM; Sachdev PS; Robinson L; Prina M; Stephan BCM, 2026, 'Development and validation of a dementia risk prediction model for low- and middle-income countries: the 10/66 study', American Journal of Epidemiology, pp. kwag116, http://dx.doi.org/10.1093/aje/kwag116

Liu D; Talevi V; Tavares JF; Wang R; Imtiaz MA; Melas K; Teumer A; Wittfeld K; Hillary RF; Vojinovic D; Beekman M; Armstrong NJ; Estrada S; Völzke H; Bülow R; Royle NA; Wardlaw JM; Wen W; Sachdev PS; Mather KA; Slagboom PE; Cox SR; Grabe HJ; Yang Q; Aziz NA; Breteler MMB, 2026, 'DNA methylation signatures of bilateral hippocampal volume, asymmetry and atrophy: a cross-omics analysis in the general population', Ebiomedicine, 128, http://dx.doi.org/10.1016/j.ebiom.2026.106289

Finch BK; Nimmagadda S; Finkel D; Gatz M; Reynolds CA; Nygaard M; Catts V; Thalamuthu A; Sachdev P; Ericsson M; Karlsson I; Thorvaldsson V; Hassing L, 2026, 'Moderating effects of educational inequality on education polygenic scores, attained education and dementia-risk relationships', Ssm Population Health, 34, http://dx.doi.org/10.1016/j.ssmph.2026.101914

Hopkins EG; Leman PJ; Cervin M; Numbers K; Brodaty H; Sachdev PS; Medvedev ON, 2026, 'Network of positive affect and depression in older adults: Twin study', Journal of Psychiatric Research, 197, pp. 321 - 329, http://dx.doi.org/10.1016/j.jpsychires.2026.02.050

Santomauro DF; Miller PA; Shadid J; Wulf Hanson S; Vo A; Roy DJ; Hagins H; Mantilla Herrera AM; Scott JG; Erskine HE; McGrath JJ; Aalruz H; Abbastabar H; Abdel Razeq NMI; Abdelgalil AA; Abdolizadeh A; Abdulah DM; Abdulmalik AE; Abebe MG; Abebe M; Abebe Getahun H; Abeldaño Zuñiga RA; Abil OZ; Aboagye RG; Abohashem S; Aborode AT; Abouelmagd ME; Abuawwad MT; Abubakar AK; Abu-Farha RK; Abuhammad S; Abuhelwa AY; Abukhadijah HJ; Aburuz S; Achore M; Adamu LH; Adamu NL; Addisu ZD; Addo IY; Adebisi TA; Adebiyi BO; Adedia D; Adedoyin RA; Adekola DO; Adekola SA; Adeleke OT; Adeniyi MA; Adesina MA; Adiga U; Adnan M; Adnani QES; Adonteng-Kissi O; Adzrago D; Affinito G; Afolabi HA; Agampodi TC; Aggarwal N; Agostinis Sobrinho C; Agwu P; Agyemang-Duah W; Ahmad AA; Ahmad K; Ahmad K; Ahmad S; Ahmad S; Ahmad T; Ahmadi NS; Ahmed A; Ahmed AM; Ahmed A; Ahmed MS; Ahmed N; Ahmed O; Ahmed SA; Ajami M; Akalanka KHM; Akhtar MN; Akosile W; Akrami AE; Al Awaidy S; Al Omari O; Al Zoubi MAM; Alalwan TA; Alam K; Al-Amer RM; Alansari AN; Alarifi A; Al-Ashwal FY; Albashtawy M; Al-Dewik N; Aldhahir AM; Alfalki AM; Algahtani FD; Alhalaiqa FN; Alhumaidi A; Ali I; Ali K; Ali MD; Ali MU; Ali R, 2026, 'Updated trends in the global prevalence and burden of mental disorders, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023', Lancet, 407, pp. 2040 - 2064, http://dx.doi.org/10.1016/S0140-6736(26)00519-2

Moss RSL; Lennon MJ; Anne S; Swift E; Lo JW; Walpola IC; Connors MH; Sachdev PS; Mohan A, 2026, 'Disability, distress and delayed access to care in functional neurological disorder: cross-sectional study from an Australian tertiary clinic', Bjpsych Open, 12, http://dx.doi.org/10.1192/bjo.2026.11038

Mewton L; Winter V; Hoy N; Visontay R; Davies S; Kochan N; Baillie A; Chapman C; Newton NC; Sunderland M; Sachdev PS; Teesson M, 2026, 'Effect of the online Rethink My Drink alcohol intervention on alcohol use and cognition in older adults in Australia: a randomised controlled trial', Lancet Public Health, 11, pp. e318 - e328, http://dx.doi.org/10.1016/S2468-2667(26)00056-3

Legaz A; Moguilner S; Barttfeld P; Cuadros Castro J; Galván Rial DS; Migeot J; Farina FR; Gonzalez-Gomez R; Salazar-Londoño S; de Souza Azzi T; Alcauter S; Amoruso L; Anghinah R; Bakr M; Behrens MI; Bruno MA; Cardona JF; Chen C; Colliot O; Custodio N; d’Acremont Q; Debette S; Dzianok P; Güntekin B; Huguet J; Jarne C; Joliot M; Karageorgiou E; Khedr EM; Koopowitz SM; Kublik E; Lee J; Aksman L; Lopez S; Margaretic P; Matallana D; Matis S; Miltiadous A; Novotni G; Orio P; Parra MA; Reppermund S; de Paula França Resende E; Salum GA; Slachevsky A; Ortiz ALS; Takada LT; Toh AQ; Tzallas A; Wen W; Whelan R; Yener G; Zegarra Valdivia JA; Alexoudi A; Arshad F; Atta H; Avila-Funes JA; Santos JB; Bruña R; Castelblanco-Toro SM; Chino Vilca BN; Coronel-Oliveros C; Crivello F; Cruzat J; Dellavale D; Dhooge C; Di Caterina G; Escudero J; Esquivias Farias JM; Eze LU; Evans TE; Farombi T; Fernández A; Fittipaldi S; Portillo F; Martinic GF; García AM; Garcia-Cordero I; Gaurav R; Godoy ME; Gonzalez Campo C; González Hernández A; Hanoğlu L; Hazelton JL; Herzog R; Ikiz B; Njamnshi AK; Landin-Romero R; López ME; Maito MA; Medel V; Sepúlveda JPM; Ochoa Gómez JF; Ogbuagu C; de Oliveira MO; Ozansoy M; Palma-Espinosa J; Hilal S; Zhou JH; Escudero SDP, 2026, 'The exposome of brain aging across 34 countries', Nature Medicine, 32, pp. 1838 - 1851, http://dx.doi.org/10.1038/s41591-026-04302-z

Chalmers RA; Cervin M; Choo C; Numbers K; Mather KA; Brodaty H; Kochan NA; Sachdev PS; Medvedev ON, 2026, 'Machine learning models for dementia risk prediction: evidence from the Sydney Memory and Ageing Study', npj Dementia, 2, http://dx.doi.org/10.1038/s44400-026-00071-1

Lennon MJ; Xu Y; Thalamuthu A; Mather K; Sachdev PS, 2026, 'Druggable genome-wide Mendelian randomization analysis identifies potential treatment targets in vascular dementia', Alzheimer S and Dementia Translational Research and Clinical Interventions, 12, http://dx.doi.org/10.1002/trc2.70258

Idrus M; Bliuc D; Mather KA; Brodaty H; Sachdev PS; Numbers K; Dai Z, 2026, 'Fermented Dairy Food Intake and Risk of Depression and Dementia in Later Life: Findings from a Prospective Cohort of Older Australians', Nutrients, 18, http://dx.doi.org/10.3390/nu18071020

Lipnicki DM; Valentí M; Valeriano-Lorenzo E; Vella AS; Zea-Sevilla MA; Ricciardi M; Frades B; Martinez M; Wagner S; Sachdev PS; del Ser T; Sanchez-Juan P, 2026, 'Poor dream recall associates with Alzheimer's disease biomarkers and dementia risk', Alzheimer S and Dementia Diagnosis Assessment and Disease Monitoring, 18, http://dx.doi.org/10.1002/dad2.70322

Xu Y; Sachdev PS; Lennon MJ, 2026, 'Vascular cognitive impairment and dementia drug-development pipeline 2025', Alzheimer S and Dementia Translational Research and Clinical Interventions, 12, http://dx.doi.org/10.1002/trc2.70263

Vella AS; Roehr S; Sachdev PS, 2026, 'The incidence of dementia in populations around the globe', Current Opinion in Psychiatry, 39, pp. 168 - 174, http://dx.doi.org/10.1097/YCO.0000000000001053

Potdar AA; Ye Y; Sachdev P; Devanarayan V; Zhang Y, 2026, 'Abstract PD3-07: Deciphering resistance mechanisms to fam-trastuzumab deruxtecan-nxki in metastatic breast cancer using real-world data', Clinical Cancer Research, 32, pp. pd3-07-pd3-07, http://dx.doi.org/10.1158/1557-3265.sabcs25-pd3-07

Ye Y; Potdar A; Apfel A; Devanarayan V; Sachdev P; Zhang Y, 2026, 'Abstract PS2-10-24: Impact of HER2 status dynamics on fam-trastuzumab deruxtecan-nxki treatment outcomes in metastatic breast cancer: real-world insights', Clinical Cancer Research, 32, pp. ps2-10-24-ps2-10-24, http://dx.doi.org/10.1158/1557-3265.sabcs25-ps2-10-24

Lo JW; Crawford JD; Desmond DW; Godefroy O; Roussel M; Bordet R; Dondaine T; Mendyk AM; Bae HJ; Lim JS; Ojagbemi A; Bello T; Chen CPLH; Chong EJ; Venketasubramanian N; Klimkowicz-Mrowiec A; Traykov L; Mehrabian S; Chung CP; Chi NF; Lau GKK; Liu DX; Welberry H; Brodaty H; Sachdev PS; Stroke ; Akinyemi R; Bath P; Brodtmann A; Cordonnier C; Douiri A; Dichgans M; Geranmayeh F; Hoffmann M; Ihara M; Kalaria R; Kandiah N; Jokinen H; Karayanidis F; Köhler S; de Kort P; Lee BC; Linden T; Markus H; Mok V; Marta-Moreno J; O'Sullivan M; Sabayan B; Srikanth V; Wardlaw J; Xu Q; Yu KH, 2026, 'Development of a Prognostic Model for Poststroke Dementia Using Multiple International Cohorts: A STROKOG Collaboration Study', Neurology, 106, http://dx.doi.org/10.1212/WNL.0000000000214574

Chalmers RA; Cervin M; Choo C; Numbers K; Mather KA; Brodaty H; Kochan NA; van den Top E; Krägeloh CU; Sachdev PS; Medvedev ON, 2026, 'Beyond biology: Physical and mental health predictors of mortality in the sydney memory and ageing study', Journal of Psychiatric Research, 193, pp. 216 - 222, http://dx.doi.org/10.1016/j.jpsychires.2025.11.033

Husein NK; Lin K; Chan DKE; Jiang J; Crawford JD; Sachdev PS; Wen W, 2026, 'Global ethnic disparities in cerebral small vessel disease imaging markers and vascular risk factors: a systematic review and meta-analysis', Alzheimer S and Dementia, 22, http://dx.doi.org/10.1002/alz.70976

Hopkins EG; Leman PJ; Cervin M; Numbers K; Brodaty H; Sachdev PS; Medvedev ON, 2026, 'Network of positive affect and depression in older adults', Journal of Affective Disorders, 394, http://dx.doi.org/10.1016/j.jad.2025.120529

Goodall LS; Lennon MJ; Sachdev PS; Gorelick PB; Kovacic JC; Samaras K, 2026, 'Current and Emerging Therapeutic Approaches for Vascular Cognitive Impairment and Dementia', Journal of the American College of Cardiology, 87, pp. 77 - 100, http://dx.doi.org/10.1016/j.jacc.2025.09.1502

Sachdev PS; Bentvelzen AC; Gustafson D; Hansra GK; Hosoki S; Jiang J; Lennon MJ; Moro MA; Saks DG; Samaras K; Kovacic JC; Kalaria R, 2026, 'Vascular Cognitive Impairment and Dementia: Clinical Features, Neuropathology, and Biomarkers', Journal of the American College of Cardiology, 87, pp. 52 - 76, http://dx.doi.org/10.1016/j.jacc.2025.11.008

Ho MP; Song Y; Sachdev PS; Fan L; Jiang J; Wen W, 2026, 'A prior-sampling conditional variational autoencoder for neuroimaging normative modelling: Benchmarking deep learning against statistical approaches', Imaging Neuroscience, 4, pp. imag.a.1098, http://dx.doi.org/10.1162/IMAG.a.1098

Powell A; Humburg P; Kochan NA; Crawford JD; Wen W; Close JCT; Sachdev PS; Brodaty H, 2026, 'Characteristics of Australian cognitive super-agers using different measurement approaches', Aging and Mental Health, 30, pp. 1763 - 1775, http://dx.doi.org/10.1080/13607863.2026.2638404

Connors MH; Sachdev PS; Teixeira-Pinto A; Crawford JD; Numbers K; Draper B; Kochan NA; Brodaty H, 2026, 'Cognition and other determinants of wellbeing in old age: a 12 year longitudinal study', Aging and Mental Health, 30, pp. 1819 - 1830, http://dx.doi.org/10.1080/13607863.2026.2643895

Sachdev PS; Bentvelzen AC, 2026, 'Editorial commentary: The usefulness of the new VasCog-2-WSO criteria for the diagnosis of vascular cognitive impairment and dementia', Cerebral Circulation Cognition and Behavior, 10, http://dx.doi.org/10.1016/j.cccb.2026.100530

Hayashi S; Du J; Fan L; Jiang J; Song Y; Wang D; Sachdev PS; Wen W, 2026, 'Factors associated with the presence, and longitudinal progression of, perivascular spaces: An exposome-wide analysis in the UK Biobank', International Journal of Stroke, http://dx.doi.org/10.1177/17474930261479041

Lam BYK; Cai Y; Zheng H; Wei J; Akinyemi R; Biessels GJ; Brink HVD; Chen C; Duering M; Gustafson D; Hilal S; Ming Ho Hui V; Kalaria R; Kim SY; Lam MLM; de Leeuw FE; Li ASM; Markus HS; Marseglia A; O’Brien J; Pantoni L; Sachdev PS; Smith EE; Wardlaw JM; Wong A; Ko H; Mok VCT, 2026, 'Global burden of cerebral small vessel disease determined from large MRI studies: A systematic review and meta-analysis', International Journal of Stroke, http://dx.doi.org/10.1177/17474930261441916

Sachdev P; Bayes A; Eyers K, 2026, 'Gordon Parker – A tribute to a legendary Australian psychiatrist', Australasian Psychiatry, http://dx.doi.org/10.1177/10398562261438766

Amjadi-Moheb F; Gobhidharan S; Mohan A; Sachdev PS; Thalamuthu A; Mather KA, 2026, 'Identification of circular RNAs associated with ageing of the dorsolateral prefrontal cortex across the adult lifespan', Neurobiology of Aging, 157, pp. 48 - 59, http://dx.doi.org/10.1016/j.neurobiolaging.2025.10.001

Samtani S; Casey AN; Thalamuthu A; Lam BCP; Catts VS; Trollor J; Brodaty H; Sachdev PS, 2026, 'The heritability of social connections among older adults and their associations with mental and cognitive health: Older Australian Twins Study', British Journal of Psychiatry, http://dx.doi.org/10.1192/bjp.2025.10505

Lok HC; Dobson-Stone C; Hallupp M; Matis S; Landin-Romero R; Guennewig B; Mundell H; Don AS; Fifita J; McCann EP; Fat SCM; Blair IP; Mather KA; Thalamuthu A; Wen W; Sachdev PS; Brooks WS; Piguet O; Halliday GM; Kim WS; Kwok JB, 2026, 'Ultra-rare variants in LAMA2 are risk factors for frontotemporal dementia and motor neuron disease', Human Molecular Genetics, 35, http://dx.doi.org/10.1093/hmg/ddag034

Lennon MJ; Sachdev PS, 2026, 'Vascular cognitive impairment and dementia: Prevention, treatments, mechanisms and management options for the future', Neuropsychopharmacology, http://dx.doi.org/10.1038/s41386-026-02331-3

Liu Z; Ding S; Liu H; Jing J; Cheng J; Zheng H; Jiang J; Wen W; Zhang Z; Zhu W; Li S; Pan Y; Cai X; Zhou Y; Liu C; Meng X; Wang Y; Li H; Jiang Y; Niu H; Kochan N; Brodaty H; Wei T; Fan Y; Li Z; Sachdev PS; Liu T; Wang Y, 2026, 'Brain Health Deviation Index: A Comprehensive Brain Health Assessment Biomarker for Predicting Cognitive Decline and Polyvascular Stenosis', Brain Health, 1, http://dx.doi.org/10.1002/brh2.70010

Poudel GR; Sachdev PS; Soloveva MV; Molina MA; Schroers R-D; Li W; Knibbs LD; Catts VS; Anstey KJ; Wen W; Jalaludin B; Brodaty H; Cerin E, 2026, 'Neighborhood street connectivity and hippocampus volume in older adults', NATURE CITIES, 3, http://dx.doi.org/10.1038/s44284-026-00408-0

Anne S; Lennon MJ; Swift E; Jervis N; Harris W; Gow K; Walpola IC; Connors M; Moss R; Crawford JD; Sachdev PS; Mohan A, 2026, 'Outcomes and Cost-Effectiveness of an Interdisciplinary Clinic for Functional Neurologic Disorders.', Neurology Clinical Practice, 16, pp. e200638, http://dx.doi.org/10.1212/cpj.0000000000200638

Hughes D; Partridge EM; Fortington L; Lennon M; Waddington G; Sachdev PS; Brodaty H, 2026, 'Promoting lifelong brain health: a review of risk factors and protective opportunities for athletes', Journal of Science and Medicine in Sport, http://dx.doi.org/10.1016/j.jsams.2026.08.201

Tardo DT; Cortes-Canteli M; Fuster V; Sachdev PS; Kovacic JC, 2025, 'The Heart-Brain-Metabolism Axis in Cardiovascular and Neurologic Disease', Journal of the American College of Cardiology, 86, pp. 2663 - 2686, http://dx.doi.org/10.1016/j.jacc.2025.09.1602

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