Risk and prognostic factors for glioma in Australia

Glioma is the most common type of brain cancer. It is extremely aggressive and yet understudied. We are conducting a family case-control study of glioma in Australia. We will (i) investigate the genetic basis of this malignancy; (ii) estimate associations with established and new environmental, lifestyle, constitutional and occupational risk factors; (iii) identify prognostic factors and estimate their association with survival; and (iv) establish a biobank of germline DNA linked to epidemiological data. We will use this new knowledge to identify people at high-risk for glioma and to group cases into homogeneous categories in order to tailor treatment and improve outcomes.