Glioma is the most common type of brain cancer. It is extremely aggressive and yet understudied. We are conducting a family case-control study of glioma in Australia. We will (i) investigate the genetic basis of this malignancy; (ii) estimate associations with established and new environmental, lifestyle, constitutional and occupational risk factors; (iii) identify prognostic factors and estimate their association with survival; and (iv) establish a biobank of germline DNA linked to epidemiological data. We will use this new knowledge to identify people at high-risk for glioma and to group cases into homogeneous categories in order to tailor treatment and improve outcomes.
Risk and prognostic factors for glioma in Australia
University of NSW– Cancer Australia Project Grant GNT1029874