Select Publications
Conference Papers
2012, 'A RANDOMIZED PHASE II STUDY OF OGX-427 PLUS PREDNISONE (P) VS. P ALONE IN PATIENTS (PTS) WITH METASTATIC CASTRATION RESISTANT PROSTATE CANCER (CRPC)', in ANNALS OF ONCOLOGY, OXFORD UNIV PRESS, AUSTRIA, Vienna, pp. 297 - 297, presented at 37th Congress of the European-Society-for-Medical-Oncology (ESMO), AUSTRIA, Vienna, 28 September 2012 - 02 October 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000309409001381&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2012, 'A phase II trial of neoadjuvant metformin in prostatic adenocarcinoma with serum and tissue biomarker evaluation.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, presented at 48th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 01 June 2012 - 06 June 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000318009802727&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2012, 'A randomized phase II study of OGX-427 plus prednisone (P) versus P alone in patients (pts) with metastatic castration resistant prostate cancer (CRPC)', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, presented at 48th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 01 June 2012 - 06 June 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000318009802873&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2012, 'A randomized, open-label, phase II study of MDV3100 alone or in combination with leuprolide and dutasteride as neoadjuvant therapy to prostatectomy in intermediate and high-risk prostate cancer', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, presented at 48th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 01 June 2012 - 06 June 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000318009803238&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2012, 'A phase II study of neoadjuvant metformin in prostatic carcinoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1538-7445.AM2012-CT-04
,2012, 'A randomized phase II study of OGX-427 plus prednisone versus prednisone alone in patients with chemotherapy-naive metastatic castration-resistant prostate cancer.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, http://dx.doi.org/10.1200/jco.2012.30.5_suppl.121
,2011, 'Mechanisms by which pantoprazole, a proton pump inhibitor, enhances the activity of doxorubicin in solid tumors', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1538-7445.AM2011-537
,2011, 'Evaluation of PTEN and TMPRSS2-ERG Abnormalities in Prostate Cancer by FISH and Immunohistochemistry To Address Intra- and Inter-Tissue Heterogeneity and Disease Progression', in LABORATORY INVESTIGATION, NATURE PUBLISHING GROUP, TX, San Antonio, pp. 393A - 393A, presented at 100th Annual Meeting of the United States and Canadian-Academy-of-Pathology, TX, San Antonio, 26 February 2011 - 04 March 2011, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000291285001328&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,Conference Posters
2020, 'P863 KEYNOTE-022 parts 4 and 5: pembrolizumab plus trametinib for patients with solid tumors or BRAF wild-type melanoma', pp. A10.2 - A11, presented at 34th Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2019): late breaking abstracts, http://dx.doi.org/10.1136/lba2019.16
,2017, 'Abiraterone +/- cabazitaxel in defining complete response in prostatectomy (ACDC-RP) trial.', IL, Chicago, Vol. 35, presented at 53rd Annual Clinical Science Meeting of the American-Society-of-Clinical-Oncology (ASCO) / Symposium on Old Targets, New Drugs - Her2 and MET, IL, Chicago, 02 June 2017 - 07 June 2017, http://dx.doi.org/10.1200/JCO.2017.35.15_suppl.TPS5095
,2017, 'Patterns of failure on Ga PSMA (GaPSMA) and F18 FDG (FDG) PET CT in a prospective phase 2 trial of Lu-177 DKFZ PSMA 617 (LuPSMA) in men with castrate resistant metastatic prostate cancer (mCRPC)', IL, Chicago, Vol. 35, presented at 53rd Annual Clinical Science Meeting of the American-Society-of-Clinical-Oncology (ASCO) / Symposium on Old Targets, New Drugs - Her2 and MET, IL, Chicago, 02 June 2017 - 07 June 2017, http://dx.doi.org/10.1200/JCO.2017.35.15_suppl.2562
,2017, 'The Molecular Screening and Therapeutics (MoST) Program: A precision medicine framework for biomarker-driven signal seeking clinical studies for rare cancers.', IL, Chicago, Vol. 35, presented at 53rd Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 02 June 2017 - 06 June 2017, http://dx.doi.org/10.1200/JCO.2017.35.15_suppl.TPS2621
,2016, 'Pantoprazole affecting docetaxel resistance pathways via autophagy (PANDORA): A phase II trial in men with metastatic castrate resistant prostate cancer (mCRPC)', Vol. 27, pp. vi249, http://dx.doi.org/10.1093/annonc/mdw372.20
,2016, 'A feasibility trial of geriatric assessment and integrated care plan for older cancer patients.', IL, Chicago, Vol. 34, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 03 June 2016 - 07 June 2016, http://dx.doi.org/10.1200/JCO.2016.34.15_suppl.10054
,2016, 'Development of the Princess Margaret Immune Oncology Prognostic Index (PM-IPI): A novel prognostic score for patients (pts) treated in immune oncology (IO) phase I (P1) trials', IL, Chicago, Vol. 34, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 03 June 2016 - 07 June 2016, http://dx.doi.org/10.1200/JCO.2016.34.15_suppl.3058
,2016, 'IDH-1/2mutations and associated oncometabolite 2-hydroxyglutarate (2-HG) in solid tumors.', IL, Chicago, Vol. 34, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 03 June 2016 - 07 June 2016, http://dx.doi.org/10.1200/JCO.2016.34.15_suppl.e23210
,2016, 'Pantoprazole affecting docetaxel resistance pathways via autophagy (PANDORA): a phase II trial in men with castration resistant prostate cancer (mCRPC).', IL, Chicago, Vol. 34, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 03 June 2016 - 07 June 2016, http://dx.doi.org/10.1200/JCO.2016.34.15_suppl.e16502
,2016, 'Immune-Related Adverse Events (irAEs) Following CTLA-4 and PD-1/PD-L1 Blockade in Advanced Melanoma: A Comprehensive Rapid Autopsy Study', WA, Seattle, Vol. 29, pp. 4A - 4A, presented at 105th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, WA, Seattle, 12 March 2016 - 18 March 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000370302500004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2016, 'Immune-Related Adverse Events (irAEs) Following CTLA-4 and PD-1/PD-L1 Blockade in Advanced Melanoma: A Comprehensive Rapid Autopsy Study', WA, Seattle, Vol. 96, pp. 4A - 4A, presented at 105th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, WA, Seattle, 12 March 2016 - 18 March 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000369270700004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2016, 'Our Rapid Research Autopsy Program: A Solid Platform for Next Generation Clinical Trials', WA, Seattle, Vol. 96, pp. 4A - 4A, presented at 105th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, WA, Seattle, 12 March 2016 - 18 March 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000369270700003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2016, 'Our Rapid Research Autopsy Program: A Solid Platform for Next Generation Clinical Trials', WA, Seattle, Vol. 29, pp. 4A - 4A, presented at 105th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, WA, Seattle, 12 March 2016 - 18 March 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000370302500003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2016, 'Unique Insights into Cardiac Metastases and Tumor Biology from a Cancer Center's Rapid Research Autopsy Program', WA, Seattle, Vol. 29, pp. 81A - 81A, presented at 105th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, WA, Seattle, 12 March 2016 - 18 March 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000370302500318&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2016, 'Unique Insights into Cardiac Metastases and Tumor Biology from a Cancer Center's Rapid Research Autopsy Program', WA, Seattle, Vol. 96, pp. 81A - 81A, presented at 105th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, WA, Seattle, 12 March 2016 - 18 March 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000369270700318&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2016, 'What is the role of comorbidity, frailty, and functional status in the decision-making process for older adults with cancer and their family members, oncologists, and family physician?', CA, San Francisco, Vol. 34, presented at Cancer Survivorship Symposium on Advancing Care and Research, CA, San Francisco, 15 January 2016 - 16 January 2016, http://dx.doi.org/10.1200/jco.2016.34.3_suppl.92
,2016, 'Correlation of a novel whole blood RT-PCR assay measuring AR-V7 expression with outcomes in metastatic castration-resistant prostate cancer (mCRPC) patients treated with abiraterone acetate (ABI).', CA, San Francisco, Vol. 34, presented at Genitourinary Cancers Symposium, CA, San Francisco, 07 January 2016 - 09 January 2016, http://dx.doi.org/10.1200/jco.2016.34.2_suppl.223
,2016, 'The utility of serum CA9 in prognostication in prostate cancer', CA, San Francisco, Vol. 34, presented at Genitourinary Cancers Symposium, CA, San Francisco, 07 January 2016 - 09 January 2016, http://dx.doi.org/10.1200/jco.2016.34.2_suppl.309
,2015, 'A phase 1/2 open-label study of safety and antitumor activity of EPI-506, a novel AR N-terminal domain inhibitor, in men with metastatic castration-resistant prostate cancer (mCRPC) with progression after enzalutamide or abiraterone.', IL, Chicago, Vol. 33, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO) / Clinical Science Symposium on Predicting and Improving Adverse Outcomes in Older Adults with Cancer, IL, Chicago, 29 May 2015 - 02 June 2015, http://dx.doi.org/10.1200/jco.2015.33.15_suppl.tps5072
,2015, 'A Phase 2 biomarker-enriched study of evofosfamide (TH-302) in patients with advanced melanoma.', IL, Chicago, Vol. 33, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO) / Clinical Science Symposium on Predicting and Improving Adverse Outcomes in Older Adults with Cancer, IL, Chicago, 29 May 2015 - 02 June 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000358036904887&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2015, 'Brain radiosurgery and ipilimumab (Ipi) in melanoma brain metastases (MBM) patients: Does an enhanced immune response induce radionecrosis (RN)?', IL, Chicago, Vol. 33, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO) / Clinical Science Symposium on Predicting and Improving Adverse Outcomes in Older Adults with Cancer, IL, Chicago, 29 May 2015 - 02 June 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000358036904043&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2015, 'Does frailty affect response to chemotherapy in older men with metastatic castration-resistant prostate cancer?', IL, Chicago, Vol. 33, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO) / Clinical Science Symposium on Predicting and Improving Adverse Outcomes in Older Adults with Cancer, IL, Chicago, 29 May 2015 - 02 June 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000358036904159&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2015, 'Molecular profiling and targeted therapy in advanced endometrial cancer.', IL, Chicago, Vol. 33, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO) / Clinical Science Symposium on Predicting and Improving Adverse Outcomes in Older Adults with Cancer, IL, Chicago, 29 May 2015 - 02 June 2015, http://dx.doi.org/10.1200/jco.2015.33.15_suppl.5589
,2015, 'Patterns of response to anti-PD1 treatment: Comparison of three radiological response criteria and effect on overall survival (OS) in metastatic melanoma patients (MM)', IL, Chicago, Vol. 33, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO) / Clinical Science Symposium on Predicting and Improving Adverse Outcomes in Older Adults with Cancer, IL, Chicago, 29 May 2015 - 02 June 2015
,2015, 'Project Data Sphere: A first look at prostate cancer including concomitant medication use, prognosis, and toxicity.', IL, Chicago, Vol. 33, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO) / Clinical Science Symposium on Predicting and Improving Adverse Outcomes in Older Adults with Cancer, IL, Chicago, 29 May 2015 - 02 June 2015, http://dx.doi.org/10.1200/jco.2015.33.15_suppl.5022
,2015, 'A pilot study of adoptive cell therapy with in vitro educated MART1 T cells in combination with ipilimumab for the treatment of metastatic melanoma', PA, Philadelphia, Vol. 75, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), PA, Philadelphia, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-CT226
,2015, 'Effect of pantoprazole to enhance activity of docetaxel against human tumor xenografts by inhibiting autophagy', PA, Philadelphia, Vol. 75, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), PA, Philadelphia, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-395
,2015, 'Exome analysis of an exceptional responder uncovers an activating GNAS mutation that may confer sensitivity to cytotoxic chemotherapy', PA, Philadelphia, Vol. 75, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), PA, Philadelphia, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-3898
,2015, 'Using functional and chemical genomics to identify mechanisms of Enzalutamide resistance in prostate cancer', PA, Philadelphia, Vol. 75, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), PA, Philadelphia, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-732
,2015, 'Project data sphere (PDS) in prostate cancer: A first look including concomitant medication use.', FL, Orlando, Vol. 33, presented at Genitourinary Cancers Symposium, FL, Orlando, 26 February 2015 - 28 February 2015, http://dx.doi.org/10.1200/jco.2015.33.7_suppl.204
,2011, 'Evaluation of PTEN and TMPRSS2-ERG abnormalities in prostate cancer by FISH and immunohistochemistry to address intra- and intertissue heterogeneity and disease progression.', Vol. 29, http://dx.doi.org/10.1200/jco.2011.29.15_suppl.4651
,2011, 'Preoperative sorafenib (Sor) and cytoreductive nephrectomy (CN) in metastatic renal cell carcinoma (mRCC)', Vol. 29, http://dx.doi.org/10.1200/jco.2011.29.15_suppl.4668
,2011, 'Use of serum and tissue biomarker analysis embedded in a phase II clinical trial of cytarabine in castration-refractory prostate cancer to investigate prostate cancer biology.', Vol. 29, http://dx.doi.org/10.1200/jco.2011.29.15_suppl.e15022
,2011, 'Evaluation of PTEN and TMPRSS2-ERG abnormalities in prostate cancer by FISH and immunohistochemistry to address intra- and inter-tissue heterogeneity and disease progression', Vol. 71, http://dx.doi.org/10.1158/1538-7445.AM2011-5074
,2011, 'Use of serum and tissue biomarker analysis embedded in a phase II clinical trial of cytarabine in castration-refractory prostate cancer to investigate prostate cancer biology', Vol. 71, http://dx.doi.org/10.1158/1538-7445.AM2011-290
,2011, 'Use of serum and tissue biomarker analysis embedded in a phase II clinical trial of cytarabine in castration-refractory prostate cancer to investigate prostate cancer biology', Vol. 29, http://dx.doi.org/10.1200/jco.2011.29.7_suppl.59
,2011, 'Evaluation of PTEN and TMPRSS2-ERG Abnormalities in Prostate Cancer by FISH and Immunohistochemistry To Address Intra- and Inter-Tissue Heterogeneity and Disease Progression', TX, San Antonio, Vol. 24, pp. 393A - 393A, presented at 100th Annual Meeting United States-and-Canadian-Academy-of-Pathology, TX, San Antonio, 26 February 2011 - 04 March 2011, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000287282302118&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2010, 'Influence of concurrent medications on outcomes of men with prostate cancer included in the TAX327 study.', Vol. 28, http://dx.doi.org/10.1200/jco.2010.28.15_suppl.4686
,2010, 'Immunohistochemical Expression of Secretory Clusterin (sCLU) in Benign and Malignant Prostate in the Context of Hormonal Therapy', DC, Washington, Vol. 23, pp. 190A - 190A, presented at 99th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, DC, Washington, 20 March 2010 - 26 March 2010, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000274582501174&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2010, 'Immunohistochemical Expression of Secretory Clusterin (sCLU) in Benign and Malignant Prostate in the Context of Hormonal Therapy', DC, Washington, Vol. 90, pp. 190A - 190A, presented at 99th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, DC, Washington, 20 March 2010 - 26 March 2010, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000274337300838&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2009, 'Correlations between telomere dysfunction and genomic instability in prostatic carcinogenesis', Vol. 69, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209701804103&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2008, 'Rationale and evidence for the use of sunitnib to treat patients with malignant paraganglioma/pheochromocytoma (MPP)', Vol. 26, http://dx.doi.org/10.1200/jco.2008.26.15_suppl.14681
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