By Associate Professor Izzy Jayasinghe

Preprints

Sheard T; Howlett L; Kirton H; Yang Z; Gurrola G; Steele D; Jayasinghe I; Valdivia H; Colyer J, 2020, Peptide ligands of the cardiac ryanodine receptor as super-resolution imaging probes, http://dx.doi.org/10.1101/2020.06.26.131854

Hurley ME; White E; Sheard TMD; Steele D; Jayasinghe I, Correlative super-resolution analysis of cardiac calcium sparks and their molecular origins in health and disease, http://dx.doi.org/10.1101/2023.02.12.528168

Ashford F; Brown E; Calagan S; Jayasinghe I; Henderson C; Fuller W; Wypijewski K, Cysteine post-translational modifications regulate protein interactions of caveolin-3, http://dx.doi.org/10.1101/2022.09.15.508083

Sheard TMD; Shakespeare T; Seehra RS; Spencer ME; Suen KM; Jayasinghe I, Differential labelling of human sub-cellular compartments with fluorescent dye esters and expansion microscopy, http://dx.doi.org/10.1101/2023.02.21.529394

Suen KM; Sheard TMD; Lin C-C; Milonaityte D; Jayasinghe I; Ladbury JE, Expansion microscopy reveals subdomains in C. elegans germ granules, http://dx.doi.org/10.1101/2022.05.29.493872

Seehra RS; Allouis BHK; Sheard TMD; Spencer ME; Shakespeare T; Cadby A; Jayasinghe I, Geometry-preserving Expansion Microscopy microplates enable high fidelity nanoscale distortion mapping, http://dx.doi.org/10.1101/2023.02.20.529230

Shakespeare T; Seehra RS; Rodriguez NF; Atuanya N; Sheard TMD; Köhler R; Bose D; Woodman P; Ciani B; Jayasinghe I, Mapping EGFR1 sorting domains in endosomes with a calibrated 3D expansion microscopy toolkit, http://dx.doi.org/10.1101/2025.10.01.678490

Sheard TMD; Hurley ME; Smith AJ; Colyer J; White E; Jayasinghe I, Molecular-scale 3D visualisation of the cardiac ryanodine receptor clusters and the molecular-scale fraying of dyads, http://dx.doi.org/10.1101/2021.10.21.462365

Narayanasamy KK; Price JC; Mesquita-Riberio R; Mather ML; Jayasinghe I, Self-activated photoblinking of nitrogen vacancy centers in nanodiamonds (sandSTORM): A method for rapid single molecule localization microscopy with unlimited observation time, http://dx.doi.org/10.1101/2020.05.20.106716

Köhler R; Hurley ME; White E; Jayasinghe I, Structural and functional heterogeneity in cardiac RyR signalling nanodomains revealed with quantitative single molecule mapping toolkit, http://dx.doi.org/10.64898/2026.07.22.740006

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