By Associate Professor Jelena Rnjak-Kovacina

Journal articles

Kim HN; Elgundi Z; Lin X; Fu L; Tang F; Moh ESX; Jung MS; Chandrasekar K; Bartlett-Tomasetig F; Foster C; Packer NH; Whitelock JM; Rnjak-Kovacina J; Lord MS, 2023, 'Engineered short forms of perlecan enhance angiogenesis by potentiating growth factor signalling', Journal of Controlled Release, 362, pp. 184 - 196, http://dx.doi.org/10.1016/j.jconrel.2023.08.052

Moore MJ; Lam YT; Santos M; Tan RP; Yang N; Hung J; Li Z; Kilian KA; Rnjak-Kovacina J; Pitts JB; Menzel H; Wise SG, 2023, 'Evaluation of the Immune Response to Chitosan-graft-poly(caprolactone) Biopolymer Scaffolds', ACS Biomaterials Science and Engineering, 9, pp. 3320 - 3334, http://dx.doi.org/10.1021/acsbiomaterials.3c00553

Lau K; Fu L; Zhang A; Akhavan B; Whitelock J; Bilek MM; Lord MS; Rnjak-Kovacina J, 2023, 'Recombinant perlecan domain V covalently immobilized on silk biomaterials via plasma immersion ion implantation supports the formation of functional endothelium', Journal of Biomedical Materials Research - Part A, 111, pp. 825 - 839, http://dx.doi.org/10.1002/jbm.a.37525

Tran HA; Hoang TT; Maraldo A; Do TN; Kaplan DL; Lim KS; Rnjak-Kovacina J, 2023, 'Emerging silk fibroin materials and their applications: New functionality arising from innovations in silk crosslinking', Materials Today, 65, pp. 244 - 259, http://dx.doi.org/10.1016/j.mattod.2023.03.027

Joukhdar H; Och Z; Tran H; Heu C; Vasquez GM; Sultana N; Stevens M; Dokos S; Lim KS; Lord MS; Rnjak-Kovacina J, 2023, 'Imparting Multi-Scalar Architectural Control into Silk Materials Using a Simple Multi-Functional Ice-Templating Fabrication Platform', Advanced Materials Technologies, 8, http://dx.doi.org/10.1002/admt.202201642

Molley TG; Jiang S; Ong L; Kopecky C; Ranaweera CD; Jalandhra GK; Milton L; Kardia E; Zhou Z; Rnjak-Kovacina J; Waters SA; Toh YC; Kilian KA, 2023, 'Gas-modulating microcapsules for spatiotemporal control of hypoxia', Proceedings of the National Academy of Sciences of the United States of America, 120, http://dx.doi.org/10.1073/pnas.2217557120

Jiang S; Wise SG; Kovacic JC; Rnjak-Kovacina J; Lord MS, 2023, 'Biomaterials containing extracellular matrix molecules as biomimetic next-generation vascular grafts', Trends in Biotechnology, http://dx.doi.org/10.1016/j.tibtech.2023.09.009

Longoni A; Major GS; Jiang S; Farrugia BL; Kieser DC; Woodfield TBF; Rnjak-Kovacina J; Lim KS, 2023, 'Pristine gelatin incorporation as a strategy to enhance the biofunctionality of poly(vinyl alcohol)-based hydrogels for tissue engineering applications', Biomaterials Science, http://dx.doi.org/10.1039/d3bm01172k

Rnjak-Kovacina J; Choi YS; Lim KS, 2022, 'Biofabrication Applications', Advanced Healthcare Materials, 11, http://dx.doi.org/10.1002/adhm.202202934

Amin ML; Deng K; Tran HA; Singh R; Rnjak-Kovacina J; Thorn P, 2022, 'Glucose-Dependent Insulin Secretion from β Cell Spheroids Is Enhanced by Embedding into Softer Alginate Hydrogels Functionalised with RGD Peptide', Bioengineering, 9, http://dx.doi.org/10.3390/bioengineering9120722

Romanazzo S; Kopecky C; Jiang S; Doshi R; Mukund V; Srivastava P; Rnjak-Kovacina J; Kelly K; Kilian KA, 2022, 'Biomaterials directed activation of a cryostable therapeutic secretome in induced pluripotent stem cell derived mesenchymal stromal cells', Journal of Tissue Engineering and Regenerative Medicine, 16, pp. 1008 - 1018, http://dx.doi.org/10.1002/term.3347

Karimi F; Lau K; Kim HN; Och Z; Lim KS; Whitelock J; Lord M; Rnjak-Kovacina J, 2022, 'Surface Biofunctionalization of Silk Biomaterials Using Dityrosine Cross-Linking', ACS Applied Materials and Interfaces, 14, pp. 31551 - 31566, http://dx.doi.org/10.1021/acsami.2c03345

Moore MJ; Tan RP; Yang N; Rnjak-Kovacina J; Wise SG, 2022, 'Bioengineering artificial blood vessels from natural materials', Trends in Biotechnology, 40, pp. 693 - 707, http://dx.doi.org/10.1016/j.tibtech.2021.11.003

Man K; Joukhdar H; Manz XD; Brunet MY; Jiang LH; Rnjak-Kovacina J; Yang XB, 2022, 'Bone tissue engineering using 3D silk scaffolds and human dental pulp stromal cells epigenetic reprogrammed with the selective histone deacetylase inhibitor MI192', Cell and Tissue Research, 388, pp. 565 - 581, http://dx.doi.org/10.1007/s00441-022-03613-0

Lau K; Heu C; Moore MJ; Zhang A; Akhavan B; Wise SG; Bilek MMM; Lord MS; Rnjak-Kovacina J, 2022, 'Effect of plasma ion immersion implantation on physiochemical and biological properties of silk towards creating a versatile biomaterial platform', Materials Today Advances, 13, http://dx.doi.org/10.1016/j.mtadv.2022.100212

Soliman BG; Major GS; Atienza-Roca P; Murphy CA; Longoni A; Alcala-Orozco CR; Rnjak-Kovacina J; Gawlitta D; Woodfield TBF; Lim KS, 2022, 'Development and Characterization of Gelatin-Norbornene Bioink to Understand the Interplay between Physical Architecture and Micro-Capillary Formation in Biofabricated Vascularized Constructs', Advanced Healthcare Materials, 11, http://dx.doi.org/10.1002/adhm.202101873

Soliman BG; Major GS; Atienza‐Roca P; Murphy CA; Longoni A; Alcala‐Orozco CR; Rnjak‐Kovacina J; Gawlitta D; Woodfield TBF; Lim KS, 2022, 'Development and Characterization of Gelatin‐Norbornene Bioink to Understand the Interplay between Physical Architecture and Micro‐Capillary Formation in Biofabricated Vascularized Constructs (Adv. Healthcare Mater. 2/2022)', Advanced Healthcare Materials, 11, pp. 2270007 - 2270007, http://dx.doi.org/10.1002/adhm.202270007

Lam YT; Tan RP; Michael PL; Lau K; Yang N; Rnjak-Kovacina J; Wise SG, 2021, 'Bioengineering silk into blood vessels', Biochemical Society Transactions, 49, pp. 2271 - 2286, http://dx.doi.org/10.1042/BST20210359

Polonchuk L; Surija L; Lee MH; Sharma P; Ming CLC; Richter F; Ben-Sefer E; Rad MA; Sarmast HMS; Al Shamery W; Tran HA; Vettori L; Haeusermann F; Filipe EC; Rnjak-Kovacina J; Cox T; Tipper J; Kabakova I; Gentile C, 2021, 'Towards engineering heart tissues from bioprinted cardiac spheroids', Biofabrication, 13, http://dx.doi.org/10.1088/1758-5090/ac14ca

Lau K; Waterhouse A; Akhavan B; Gao L; Kim HN; Tang F; Whitelock JM; Bilek MM; Lord MS; Rnjak-Kovacina J, 2021, 'Biomimetic silk biomaterials: Perlecan-functionalized silk fibroin for use in blood-contacting devices', Acta Biomaterialia, 132, pp. 162 - 175, http://dx.doi.org/10.1016/j.actbio.2021.02.014

Monfared M; Mawad D; Rnjak-Kovacina J; Stenzel MH, 2021, '3D bioprinting of dual-crosslinked nanocellulose hydrogels for tissue engineering applications', Journal of Materials Chemistry B, 9, pp. 6163 - 6175, http://dx.doi.org/10.1039/d1tb00624j

Joukhdar H; Seifert A; Jüngst T; Groll J; Lord MS; Rnjak-Kovacina J, 2021, 'Ice Templating Soft Matter: Fundamental Principles and Fabrication Approaches to Tailor Pore Structure and Morphology and Their Biomedical Applications', Advanced Materials, 33, http://dx.doi.org/10.1002/adma.202100091

Yang N; Moore MJ; Michael PL; Santos M; Lam YT; Bao S; Ng MKC; Rnjak-Kovacina J; Tan RP; Wise SG, 2021, 'Silk Fibroin Scaffold Architecture Regulates Inflammatory Responses and Engraftment of Bone Marrow-Mononuclear Cells', Advanced Healthcare Materials, 10, http://dx.doi.org/10.1002/adhm.202100615

Longoni A; Li J; Lindberg GCJ; Rnjak-Kovacina J; Wise LM; Hooper GJ; Woodfield TBF; Kieser DC; Lim KS, 2021, 'Strategies for inclusion of growth factors into 3D printed bone grafts', Essays in Biochemistry, 65, pp. 569 - 585, http://dx.doi.org/10.1042/EBC20200130

Chandrasekar K; Farrugia BL; Johnson L; Marks D; Irving D; Elgundi Z; Lau K; Kim HN; Rnjak-Kovacina J; Bilek MM; Whitelock JM; Lord MS, 2021, 'Effect of Recombinant Human Perlecan Domain V Tethering Method on Protein Orientation and Blood Contacting Activity on Polyvinyl Chloride', Advanced Healthcare Materials, 10, http://dx.doi.org/10.1002/adhm.202100388

Yan Y; Travaglini L; Lau K; Rnjak-Kovacina J; Ta D; Eslami M; Yang S; Lauto A; Officer DL; Mawad D, 2021, 'Impact of Sterilization on a Conjugated Polymer-Based Bioelectronic Patch', ACS Applied Polymer Materials, 3, pp. 2541 - 2552, http://dx.doi.org/10.1021/acsapm.1c00131

Baptista M; Joukhdar H; Alcala-Orozco CR; Lau K; Jiang S; Cui X; He S; Tang F; Heu C; Woodfield TBF; Lim KS; Rnjak-Kovacina J, 2020, 'Silk fibroin photo-lyogels containing microchannels as a biomaterial platform for: In situ tissue engineering', Biomaterials Science, 8, pp. 7093 - 7105, http://dx.doi.org/10.1039/d0bm01010c

Eslami M; Zeglio E; Alosaimi G; Yan Y; Ruprai H; Macmillan A; Seidel J; Lauto A; Joukhdar H; Rnjak-Kovacina J; Mawad D, 2020, 'A One Step Procedure toward Conductive Suspensions of Liposome-Polyaniline Complexes', Macromolecular Bioscience, 20, http://dx.doi.org/10.1002/mabi.202000103

Cui X; Soliman BG; Alcala-Orozco CR; Li J; Vis MAM; Santos M; Wise SG; Levato R; Malda J; Woodfield TBF; Rnjak-Kovacina J; Lim KS, 2020, 'Correction to: Rapid Photocrosslinking of Silk Hydrogels with High Cell Density and Enhanced Shape Fidelity (Adv. Healthcare Mater, (2020), 9, (1901667), 10.1002/adhm.201901667)', Advanced Healthcare Materials, 9, http://dx.doi.org/10.1002/adhm.202001801

Lau K; Akhavan B; Lord MS; Bilek MM; Rnjak-Kovacina J, 2020, 'Dry Surface Treatments of Silk Biomaterials and Their Utility in Biomedical Applications', ACS Biomaterials Science and Engineering, 6, pp. 5431 - 5452, http://dx.doi.org/10.1021/acsbiomaterials.0c00888

Atienza-Roca P; Kieser DC; Cui X; Bathish B; Ramaswamy Y; Hooper GJ; Clarkson AN; Rnjak-Kovacina J; Martens PJ; Wise LM; Woodfield TBF; Lim KS, 2020, 'Visible light mediated PVA-tyramine hydrogels for covalent incorporation and tailorable release of functional growth factors', Biomaterials Science, 8, pp. 5005 - 5019, http://dx.doi.org/10.1039/d0bm00603c

Lin X; Tang F; Jiang S; Khamis H; Bongers A; Whitelock JM; Lord MS; Rnjak-Kovacina J, 2020, 'A Biomimetic Approach toward Enhancing Angiogenesis: Recombinantly Expressed Domain V of Human Perlecan Is a Bioactive Molecule That Promotes Angiogenesis and Vascularization of Implanted Biomaterials', Adv. Sci., 7, pp. 2000900, http://dx.doi.org/10.1002/advs.202000900

Tang F; Manz XD; Bongers A; Odell RA; Joukhdar H; Whitelock JM; Lord MS; Rnjak-Kovacina J, 2020, 'Microchannels are an architectural cue that promotes integration and vascularization of silk biomaterials in vivo', ACS Biomaterials Science and Engineering, 6, pp. 1476 - 1486, http://dx.doi.org/10.1021/acsbiomaterials.9b01624

Cui X; Soliman BG; Alcala-Orozco CR; Li J; Vis MAM; Santos M; Wise SG; Levato R; Malda J; Woodfield TBF; Rnjak-Kovacina J; Lim KS, 2020, 'Rapid Photocrosslinking of Silk Hydrogels with High Cell Density and Enhanced Shape Fidelity', Advanced Healthcare Materials, 9, http://dx.doi.org/10.1002/adhm.201901667

Vettori L; Sharma P; Rnjak-Kovacina J; Gentile C, 2020, '3D Bioprinting of Cardiovascular Tissues for In Vivo and In Vitro Applications Using Hybrid Hydrogels Containing Silk Fibroin: State of the Art and Challenges', Current Tissue Microenvironment Reports, 1, pp. 261 - 276, http://dx.doi.org/10.1007/s43152-020-00026-5

Chan AHP; Filipe EC; Tan RP; Santos M; Yang N; Hung J; Feng J; Nazir S; Benn AJ; Ng MKC; Rnjak-Kovacina J; Wise SG, 2019, 'Altered processing enhances the efficacy of small-diameter silk fibroin vascular grafts', Scientific Reports, 9, http://dx.doi.org/10.1038/s41598-019-53972-y

Rnjak-Kovacina J; Gerrand YW; Wray LS; Tan B; Joukhdar H; Kaplan DL; Morrison WA; Mitchell GM, 2019, 'Vascular Pedicle and Microchannels: Simple Methods Toward Effective In Vivo Vascularization of 3D Scaffolds', Advanced Healthcare Materials, 8, http://dx.doi.org/10.1002/adhm.201901106

Lim KS; Baptista M; Moon S; Woodfield TBF; Rnjak-Kovacina J, 2019, 'Microchannels in Development, Survival, and Vascularisation of Tissue Analogues for Regenerative Medicine', Trends in Biotechnology, 37, pp. 1189 - 1201, http://dx.doi.org/10.1016/j.tibtech.2019.04.004

Holland C; Numata K; Rnjak-Kovacina J; Seib FP, 2019, 'The Biomedical Use of Silk: Past, Present, Future', Advanced Healthcare Materials, 8, http://dx.doi.org/10.1002/adhm.201800465

Lord MS; Tang F; Rnjak-Kovacina J; Smith JGW; Melrose J; Whitelock JM, 2018, 'The multifaceted roles of perlecan in fibrosis', Matrix Biology, 68-69, pp. 150 - 166, http://dx.doi.org/10.1016/j.matbio.2018.02.013

Kondyurin A; Lau K; Tang F; Akhavan B; Chrzanowski W; Lord MS; Rnjak-Kovacina J; Bilek MM, 2018, 'Plasma Ion Implantation of Silk Biomaterials Enabling Direct Covalent Immobilization of Bioactive Agents for Enhanced Cellular Responses', ACS Applied Materials and Interfaces, 10, pp. 17605 - 17616, http://dx.doi.org/10.1021/acsami.8b03182

Lord M; Rnjak-Kovacina J; Tang F; Whitelock J, 2018, 'Glycosaminoglycan and Proteoglycan-Based Biomaterials: Current Trends and Future Perspectives', Advanced Healthcare Materials, 7, pp. 1701042 - 1701042, http://dx.doi.org/10.1002/adhm.201701042

Tan RP; Chan AHP; Lennartsson K; Miravet MM; Lee BSL; Rnjak-Kovacina J; Clayton ZE; Cooke JP; Ng MKC; Patel S; Wise SG, 2018, 'Integration of induced pluripotent stem cell-derived endothelial cells with polycaprolactone/gelatin-based electrospun scaffolds for enhanced therapeutic angiogenesis', Stem Cell Research and Therapy, 9, http://dx.doi.org/10.1186/s13287-018-0824-2

Filipe EC; Santos M; Hung J; Lee BSL; Yang N; Chan AHP; Ng MKC; Rnjak-Kovacina J; Wise SG, 2018, 'Rapid Endothelialization of Off-the-Shelf Small Diameter Silk Vascular Grafts', JACC: Basic to Translational Science, 3, pp. 38 - 53, http://dx.doi.org/10.1016/j.jacbts.2017.12.003

Rnjak-Kovacina J; Tang F; Lin X; Whitelock JM; Lord MS, 2017, 'Recombinant Domain V of Human Perlecan Is a Bioactive Vascular Proteoglycan', Biotechnology Journal, 12, http://dx.doi.org/10.1002/biot.201700196

Rnjak-Kovacina J; Tang F; Whitelock JM; Lord MS, 2016, 'Silk biomaterials functionalized with recombinant domain V of human perlecan modulate endothelial cell and platelet interactions for vascular applications', Colloids and Surfaces B: Biointerfaces, 148, pp. 130 - 138, http://dx.doi.org/10.1016/j.colsurfb.2016.08.039

Lord MS; Cheng B; Tang F; Lyons JG; Rnjak-Kovacina J; Whitelock JM, 2016, 'Bioengineered human heparin with anticoagulant activity', Metabolic Engineering, 38, pp. 105 - 114, http://dx.doi.org/10.1016/j.ymben.2016.07.006

Roberts JJ; Farrugia BL; Green RA; Rnjak-Kovacina J; Martens PJ, 2016, 'In situ formation of poly(vinyl alcohol)–heparin hydrogels for mild encapsulation and prolonged release of basic fibroblast growth factor and vascular endothelial growth factor', Journal of Tissue Engineering, 7, http://dx.doi.org/10.1177/2041731416677132

Ghezzi CE; Wang L; Behlau I; Rnjak-Kovacina J; Wang S; Goldstein MH; Liu J; Marchant JK; Rosenblatt MI; Kaplan DL, 2016, 'Degradation of silk films in multipocket corneal stromal rabbit models', Journal of Applied Biomaterials and Functional Materials, 14, pp. e266 - e276, http://dx.doi.org/10.5301/jabfm.5000274

Lord M; Chuang C; Rnjak‐Kovacina J; Cheng B; Lyons G; Whitelock J, 2016, 'Bioengineering Proteoglycan‐based Matrices For Blood Contacting Applications', The FASEB Journal, 30, http://dx.doi.org/10.1096/fasebj.30.1_supplement.622.2

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