By Dr Alexis Estelle Whitton

Journal articles

Whitton AE; Webb CA; Dillon DG; Kayser J; Rutherford A; Goer F; Fava M; McGrath P; Weissman M; Parsey R; Adams P; Trombello JM; Cooper C; Deldin P; Oquendo MA; McInnis MG; Carmody T; Bruder G; Trivedi MH; Pizzagalli DA, 2019, 'Pretreatment Rostral Anterior Cingulate Cortex Connectivity With Salience Network Predicts Depression Recovery: Findings From the EMBARC Randomized Clinical Trial', Biological Psychiatry, 85, pp. 872 - 880, http://dx.doi.org/10.1016/j.biopsych.2018.12.007

Finan PH; Whitton AE; Letzen JE; Remeniuk B; Robinson ML; Irwin MR; Pizzagalli DA; Smith MT, 2019, 'Experimental sleep disruption and reward learning: Moderating role of positive affect responses', Sleep, 42, http://dx.doi.org/10.1093/sleep/zsz026

Sperl MFJ; Panitz C; Rosso IM; Dillon DG; Kumar P; Hermann A; Whitton AE; Hermann C; Pizzagalli DA; Mueller EM, 2019, 'Fear Extinction Recall Modulates Human Frontomedial Theta and Amygdala Activity', Cerebral Cortex, 29, pp. 701 - 715, http://dx.doi.org/10.1093/cercor/bhx353

Kaiser RH; Treadway MT; Wooten DW; Kumar P; Goer F; Murray L; Beltzer M; Pechtel P; Whitton A; Cohen AL; Alpert NM; El Fakhri G; Normandin MD; Pizzagalli DA, 2018, 'Frontostriatal and dopamine markers of individual differences in reinforcement learning: A multi-modal investigation', Cerebral Cortex, 28, pp. 4281 - 4290, http://dx.doi.org/10.1093/cercor/bhx281

Schneier FR; Slifstein M; Whitton AE; Pizzagalli DA; Reinen J; McGrath PJ; Iosifescu DV; Abi-Dargham A, 2018, 'Dopamine Release in Antidepressant-Naive Major Depressive Disorder: A Multimodal [¹¹C]-(+)-PHNO Positron Emission Tomography and Functional Magnetic Resonance Imaging Study', Biological Psychiatry, 84, pp. 563 - 573, http://dx.doi.org/10.1016/j.biopsych.2018.05.014

Whitton AE; Mehta M; Ironside ML; Murray G; Pizzagalli DA, 2018, 'Evidence of a diurnal rhythm in implicit reward learning', Chronobiology International, 35, pp. 1104 - 1114, http://dx.doi.org/10.1080/07420528.2018.1459662

Schneier F; Slifstein M; Whitton A; Pizzagalli D; Reinen J; McGrath P; Iosifescu D; Abi-Dargham A, 2018, 'Dopamine Release in Treatment-Naive Major Depressive Disorder: A [11C]-(+)-PHNO Positron Emission Tomography Study', BIOLOGICAL PSYCHIATRY, 83, pp. S101 - S101, http://dx.doi.org/10.1016/j.biopsych.2018.02.270

Whitton A; Green A; Pizzagalli D; Williams J; Brunette M, 2018, 'Potent Dopamine D2 Receptor Antagonists Block the Reward-Enhancing Effects of Nicotine in Smokers With Schizophrenia', BIOLOGICAL PSYCHIATRY, 83, pp. S443 - S443, http://dx.doi.org/10.1016/j.biopsych.2018.02.1136

Robinson ML; Whitton AE; Remeniuk B; Smith MT; Letzen JE; Irwin MR; Pizzagalli DA; Finan PH, 2018, '0099 Effects of Sleep Disruption on Reward Learning in Healthy Adults', Sleep, 41, pp. A40 - A40, http://dx.doi.org/10.1093/sleep/zsy061.098

Nangle MR; Bailey PE; Henry JD; Khlentzos GS; Varcin KJ; Whitton AE, 2018, 'Age invariance in rapid facial affective reactions to emotionally valenced stimuli', Quarterly Journal of Experimental Psychology, 71, pp. 1687 - 1697, http://dx.doi.org/10.1080/17470218.2017.1345960

Whitton AE; Deccy S; Ironside ML; Kumar P; Beltzer M; Pizzagalli DA, 2018, 'Electroencephalography Source Functional Connectivity Reveals Abnormal High-Frequency Communication Among Large-Scale Functional Networks in Depression', Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 3, pp. 50 - 58, http://dx.doi.org/10.1016/j.bpsc.2017.07.001

Whitton AE; Van't Veer A; Kakani P; Dillon DG; Ironside ML; Haile A; Crowley DJ; Pizzagalli DA, 2017, 'Acute stress impairs frontocingulate activation during error monitoring in remitted depression', Psychoneuroendocrinology, 75, pp. 164 - 172, http://dx.doi.org/10.1016/j.psyneuen.2016.10.007

Whitton AE; Kakani P; Foti D; Van'T Veer A; Haile A; Crowley DJ; Pizzagalli DA, 2016, 'Blunted Neural Responses to Reward in Remitted Major Depression: A High-Density Event-Related Potential Study', Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 1, pp. 87 - 95, http://dx.doi.org/10.1016/j.bpsc.2015.09.007

Lewandowski KE; Whitton AE; Pizzagalli DA; Norris LA; Ongur D; Hall MH, 2016, 'Reward learning, neurocognition, social cognition, and symptomatology in psychosis', Frontiers in Psychiatry, 7, http://dx.doi.org/10.3389/fpsyt.2016.00100

Clarke J; Proudfoot J; Whitton A; Birch MR; Boyd M; Parker G; Manicavasagar V; Hadzi-Pavlovic D; Fogarty A, 2016, 'Therapeutic Alliance With a Fully Automated Mobile Phone and Web-Based Intervention: Secondary Analysis of a Randomized Controlled Trial', JMIR Mental Health, 3, http://dx.doi.org/10.2196/mental.4656

Peechatka AL; Whitton AE; Farmer SL; Pizzagalli DA; Janes AC, 2015, 'Cigarette craving is associated with blunted reward processing in nicotine-dependent smokers', Drug and Alcohol Dependence, 155, pp. 202 - 207, http://dx.doi.org/10.1016/j.drugalcdep.2015.07.015

Janes AC; Pedrelli P; Whitton AE; Pechtel P; Douglas S; Martinson MA; Huz I; Fava M; Pizzagalli DA; Evins AE, 2015, 'Reward responsiveness varies by smoking status in women with a history of major depressive disorder', Neuropsychopharmacology, 40, pp. 1940 - 1946, http://dx.doi.org/10.1038/npp.2015.43

Whitton AE; Henry JD; Grisham JR, 2015, 'Cognitive and psychophysiological correlates of disgust in obsessive-compulsive disorder', British Journal of Clinical Psychology, 54, pp. 16 - 33, http://dx.doi.org/10.1111/bjc.12058

Whitton AE; Treadway MT; Pizzagalli DA, 2015, 'Reward processing dysfunction in major depression, bipolar disorder and schizophrenia', Current Opinion in Psychiatry, 28, pp. 7 - 12, http://dx.doi.org/10.1097/YCO.0000000000000122

Whitton AE; Proudfoot J; Clarke J; Birch MR; Parker G; Manicavasagar V; Hadzi-Pavlovic D, 2015, 'Breaking open the black box: Isolating the most potent features of a web and mobile phone-based intervention for depression, anxiety, and stress', JMIR Mental Health, 2, http://dx.doi.org/10.2196/mental.3573

Peechatka AL; Whitton AE; Farmer SL; Pizzagalli DA; Janes A, 2015, 'Cigarette craving is associated with blunted reward processing in nicotine-dependent smokers', Drug and Alcohol Dependence, 156, pp. e175 - e175, http://dx.doi.org/10.1016/j.drugalcdep.2015.07.475

Grisham JR; Becker L; Williams AD; Whitton AE; Makkar SR, 2014, 'Using Cognitive Bias Modification to Deflate Responsibility in Compulsive Checkers', Cognitive Therapy and Research, 38, pp. 505 - 517, http://dx.doi.org/10.1007/s10608-014-9621-0

Clarke J; Proudfoot J; Birch MR; Whitton AE; Parker G; Manicavasagar V; Harrison V; Christensen H; Hadzi-Pavlovic D, 2014, 'Effects of mental health self-efficacy on outcomes of a mobile phone and web intervention for mild-to-moderate depression, anxiety and stress: Secondary analysis of a randomised controlled trial', BMC Psychiatry, 14, pp. 272, http://dx.doi.org/10.1186/s12888-014-0272-1

Proudfoot J; Whitton AE; Parker G; Manicavasagar V; Nicholas J; Smith M, 2014, 'Evidence of weekly cyclicity in mood and functional impairment in those with a bipolar disorder', Psychiatry Research, 218, pp. 290 - 294, http://dx.doi.org/10.1016/j.psychres.2014.04.047

Grisham JR; Becker L; Williams AD; Whitton AE; Makkar SR, 2014, 'Using Cognitive Bias Modification to Deflate Responsibility in Compulsive Checkers', Cognitive Therapy and Research, 38, pp. 505 - 517, http://dx.doi.org/10.1007/s10608-014-9621-0

Whitton AE; Henry JD; Rendell PG; Grisham JR, 2014, 'Disgust, but not anger provocation, enhances levator labii superioris activity during exposure to moral transgressions', Biological Psychology, 96, pp. 48 - 56, http://dx.doi.org/10.1016/j.biopsycho.2013.11.012

Whitton AE; Henry JD; Grisham JR, 2014, 'Moral rigidity in obsessive-compulsive disorder: Do abnormalities in inhibitory control, cognitive flexibility and disgust play a role?', Journal of Behavior Therapy and Experimental Psychiatry, 45, pp. 152 - 159, http://dx.doi.org/10.1016/j.jbtep.2013.10.001

Proudfoot J; Clarke J; Birch MR; Whitton AE; Parker G; Manicavasagar V; Harrison V; Christensen H; Hadzi-Pavlovic D, 2013, 'Impact of a mobile phone and web program on symptom and functional outcomes for people with mild-to-moderate depression, anxiety and stress: A randomised controlled trial', BMC Psychiatry, 13, pp. 312, http://dx.doi.org/10.1186/1471-244X-13-312

Whitton AE; Grisham JR; Henry JD; Palada HD, 2013, 'Interpretive Bias Modification for Disgust', JOURNAL OF EXPERIMENTAL PSYCHOPATHOLOGY, 4, pp. 341 - 359, http://dx.doi.org/10.5127/jep.030812

Proudfoot JG; Parker GB; Manicavasagar VL; Hadzi-Pavlovic D; Whitton ; Nicholas J; Smith M; Burckhardt R; Burckhardt , 2012, 'Effects of adjunctive peer support on perceptions of illness control and understanding in an online psychoeducation program for bipolar disorder: A randomised controlled trial', Journal of Affective Disorders, 142, pp. 98 - 105

Proudfoot JG; Jayawant A; Whitton ; Parker GB; Manicavasagar VL; Smith M; Nicholas J, 2012, 'Mechanisms underpinning effective peer support: a qualitative analysis of interactions between expert peers and patients newly-diagnosed with bipolar disorder', BMC Psychiatry, 12, pp. 1 - 20, http://dx.doi.org/10.1186/1471-244X-12-196

Whitton AE; Henry JD, 2012, 'The relationship between sub-clinical obsessive-compulsive symptoms and social cognition in chronic schizophrenia.', British Journal of Clinical Psychology, 52, pp. 115 - 128, http://dx.doi.org/10.1111/bjc.12004

Proudfoot JG; Whitton ; Parker GB; Doran J; Manicavasagar VL; Delmas K, 2012, 'Triggers of mania and depression in young adults with bipolar disorder', Journal of Affective Disorders, 143, pp. 196 - 202, http://dx.doi.org/10.1016/j.jad.2012.05.052

Conference Papers

O'Dea B; Braund TA; Batterham PJ; Larsen ME; Glozier N; Whitton AE, 2024, 'Reading Between the Lines: Identifying the Linguistic Markers of Anhedonia for the Stratification of Depression', in Conference on Human Factors in Computing Systems - Proceedings, http://dx.doi.org/10.1145/3613904.3642478

Whitton A; Hardy R; Cope K; O'Dea B; Cockayne N; Newby J, 2021, 'Effectiveness of a digital mental health screening and clinical decision aid for promoting uptake of eMental Health interventions in Australian general practices', in AUSTRALIAN JOURNAL OF PRIMARY HEALTH, CSIRO PUBLISHING, pp. LV - LV, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000681602200101&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Whitton A; Henry JD; Grisham JR; Rendell PG, 2012, 'Hoarding, excessive responsibility and pathological guilt: Symptoms of empathy in overdrive?', in INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY, ELSEVIER SCIENCE BV, ITALY, Pisa, pp. 321 - 321, presented at 16th World Congress of Psychophysiology of the International Organization of Psychophysiology (IOP), ITALY, Pisa, 13 September 2012 - 17 September 2012, http://dx.doi.org/10.1016/j.ijpsycho.2012.06.086

Conference Presentations

Whitton A, 2020, 'Novel approaches for classifying and treating individuals with anhedonia', presented at Australiasian Society for Bipolar & Depressive Disorders Virtual Symposium Series, Virtual, 18 November 2020

Whitton A, 2020, 'Effectiveness of a stepped mental health service for improving the identification and treatment of depression and anxiety in primary care', presented at Australian Society for Medical Research NSW Annual Scientific Meeting, Virtual, 13 November 2020 - 13 November 2020

Conference Abstracts

Tran D; McNair N; Whitton A; Whitford T; Livesey E, 2023, 'The predictive brain: Linking motor and sensory attenuation using combined TMS-EEG', in Brain Stimulation, Elsevier BV, Vol. 16, pp. 260 - 260, http://dx.doi.org/10.1016/j.brs.2023.01.428

Reinen J; Whitton A; Pizzagalli D; Silfstein M; Abi-Dargham A; McGrath P; Iosifescu DV; Schneier F, 2018, 'Major Depressive Disorder is Associated With Blunted Learning Signals in Medial Prefrontal Cortex and Putamen When Seeking Monetary Reward', in BIOLOGICAL PSYCHIATRY, ELSEVIER SCIENCE INC, NY, New York, Vol. 83, pp. S101 - S102, presented at 73rd Annual Scientific Convention and Meeting of the Society-of-Biological-Psychiatry (SOBP), NY, New York, 10 May 2018 - 12 May 2018, http://dx.doi.org/10.1016/j.biopsych.2018.02.271

Whitton A; Reinen J; Slifstein M; McGrath P; Iosifescu D; Abi-Dargham A; Pizzagalli D; Schneier F, 2018, 'Utilizing a Behavioral Assay of Reward Learning to Predict Clinical Response to a Dopamine Agonist in Individuals With Depression', in BIOLOGICAL PSYCHIATRY, ELSEVIER SCIENCE INC, NY, New York, Vol. 83, pp. S102 - S102, presented at 73rd Annual Scientific Convention and Meeting of the Society-of-Biological-Psychiatry (SOBP), NY, New York, 10 May 2018 - 12 May 2018, http://dx.doi.org/10.1016/j.biopsych.2018.02.272

Pizzagalli D; Whitton A; Van't Veer A; Donahue R; Carlezon W, 2017, 'Aberrant Error Processing in Depressive Phenotypes: Cross-species Confluence and Initial Electrophysiological Markers', in BIOLOGICAL PSYCHIATRY, ELSEVIER SCIENCE INC, CA, San Diego, Vol. 81, pp. S315 - S315, presented at 72nd Annual Scientific Convention and Meeting of the Society-of-Biological-Psychiatry (SOBP), CA, San Diego, 18 May 2017 - 20 May 2017, http://dx.doi.org/10.1016/j.biopsych.2017.02.842

Whitton A; Pizzagalli D, 2017, 'Spectral EEG Dynamics of Large-Scale Functional Network Disturbances in Depression', in BIOLOGICAL PSYCHIATRY, ELSEVIER SCIENCE INC, CA, San Diego, Vol. 81, pp. S58 - S58, presented at 72nd Annual Scientific Convention and Meeting of the Society-of-Biological-Psychiatry (SOBP), CA, San Diego, 18 May 2017 - 20 May 2017, http://dx.doi.org/10.1016/j.biopsych.2017.02.151

Eren CY; Sancak S; Yazici D; Uysal SP; Whitton A; Rutherford A; Pizzagalli D; Eser HY, 2017, 'Effect of GLP-1 Agonists Use on Cognitive and Affective Functioning in Type 2 Diabetes Mellitus Patients: A Preliminary Study', in BIOLOGICAL PSYCHIATRY, ELSEVIER SCIENCE INC, NY, New York, Vol. 83, pp. S385 - S385, presented at 73rd Annual Scientific Convention and Meeting of the Society-of-Biological-Psychiatry (SOBP), NY, New York, 10 May 2017 - 12 May 2017, http://dx.doi.org/10.1016/j.biopsych.2018.02.989

Rutherford A; Whitton AE; Ironside ML; Jensen JE; Du F; Farabaugh A; Deckersbach T; Ongur D; Pizzagalli DA, 2017, 'Rostral Anterior Cingulate Glutamate Levels are Linked to Abnormal High-Frequency Resting-State Functional Connectivity in Bipolar Disorder', in BIOLOGICAL PSYCHIATRY, ELSEVIER SCIENCE INC, NY, New York, Vol. 83, pp. S271 - S271, presented at 73rd Annual Scientific Convention and Meeting of the Society-of-Biological-Psychiatry (SOBP), NY, New York, 10 May 2017 - 12 May 2017, http://dx.doi.org/10.1016/j.biopsych.2018.02.700

, 2017, 'Abstracts of the WASAD Conference 2017, 14-16 September, Würzburg, Germany.', in J Neural Transm (Vienna), Austria, Vol. 124, pp. 1277 - 1328, Austria, http://dx.doi.org/10.1007/s00702-017-1777-9

, 2017, 'ACNP 56th Annual Meeting: Poster Session III, December 6, 2017', in Neuropsychopharmacology, Springer Science and Business Media LLC, Vol. 42, pp. S476 - S652, http://dx.doi.org/10.1038/npp.2017.266

, 2016, 'Poster Session Abstracts', in Psychophysiology, Wiley, Vol. 53, http://dx.doi.org/10.1111/psyp.12719

Hall MH; Whitton A; Mallya S; Douglas S; Spencer K; Cohen B; Levy D; Smoller J; Oenguer D; Pizzagalli D, 2015, 'Associations among reward-based learning, mood and anxiety symptoms, and their relation to brain neurophysiology in schizophrenia and bipolar disorder', in BIPOLAR DISORDERS, WILEY-BLACKWELL, Vol. 17, pp. 101 - 101, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000355338100280&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Whitton AE; Henry JD; Rendell PG; Grisham JR, 2012, 'Pathological disgust and the basal ganglia: An examination of disgust responding in obsessive-compulsive disorder', in INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY, ELSEVIER SCIENCE BV, ITALY, Pisa, Vol. 85, pp. 365 - 365, presented at 16th World Congress of Psychophysiology of the International Organization of Psychophysiology (IOP), ITALY, Pisa, 13 September 2012 - 17 September 2012, http://dx.doi.org/10.1016/j.ijpsycho.2012.07.010

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