Select Publications
Book Chapters
2022, 'The Alimentary Tract and Exocrine Pancreas', in Keeling's Fetal and Neonatal Pathology, pp. 551 - 595, http://dx.doi.org/10.1007/978-3-030-84168-3_22
,Journal articles
2024, 'A Phase 1 Study of Intravenous EGFR-ErbituxEDVsMIT in Children with Solid or CNS Tumours Expressing Epidermal Growth Factor Receptor', Targeted Oncology, http://dx.doi.org/10.1007/s11523-024-01051-2
,2023, 'A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer', Genome Medicine, 15, http://dx.doi.org/10.1186/s13073-023-01170-x
,2023, 'Histone H3-wild type diffuse midline gliomas with H3K27me3 loss are a distinct entity with exclusive EGFR or ACVR1 mutation and differential methylation of homeobox genes', Scientific Reports, 13, http://dx.doi.org/10.1038/s41598-023-30395-4
,2023, 'A Primer for Research Scientists on Assessing Mouse Gross and Histopathology Images in the Biomedical Literature', Current Protocols, 3, http://dx.doi.org/10.1002/cpz1.891
,2023, 'High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer', Cancer Research, 83, pp. 2716 - 2732, http://dx.doi.org/10.1158/0008-5472.CAN-22-3702
,2023, 'Precision Medicine Is Changing the Roles of Healthcare Professionals, Scientists, and Research Staff: Learnings from a Childhood Cancer Precision Medicine Trial', Journal of Personalized Medicine, 13, http://dx.doi.org/10.3390/jpm13071033
,2023, 'Improved local diagnosis of focal hyperinsulinism in the COVID-19 era by interstate radiopharmaceutical transport', Journal of Paediatrics and Child Health, 59, pp. 398 - 400, http://dx.doi.org/10.1111/jpc.16307
,2023, 'Fetal Lung Interstitial Tumor (FLIT): A case series', Journal of Neonatal Surgery, 12, http://dx.doi.org/10.47338/jns.v12.1141
,2022, 'In vitro and in vivo drug screens of tumor cells identify novel therapies for high-risk child cancer', EMBO Molecular Medicine, 14, pp. e14608, http://dx.doi.org/10.15252/emmm.202114608
,2022, 'Inhibition of mitochondrial translocase SLC25A5 and histone deacetylation is an effective combination therapy in neuroblastoma', International Journal of Cancer, 152, pp. 1399 - 1413, http://dx.doi.org/10.1002/ijc.34349
,2021, 'A Primer for Assessing the Pathology in Mouse Models of Neuroblastoma', Current Protocols, 1, pp. e310, http://dx.doi.org/10.1002/cpz1.310
,2021, 'Dual targeting of chromatin stability by the curaxin CBL0137 and histone deacetylase inhibitor panobinostat shows significant preclinical efficacy in neuroblastoma', Clinical Cancer Research, 27, pp. 4338 - 4352, http://dx.doi.org/10.1158/1078-0432.CCR-20-2357
,2021, 'Exploiting the reactive oxygen species imbalance in high-risk paediatric acute lymphoblastic leukaemia through auranofin', British Journal of Cancer, 125, pp. 55 - 64, http://dx.doi.org/10.1038/s41416-021-01332-x
,2021, 'Parents' experiences of postmortem tumor donation for high-grade gliomas: Benefits and suggested improvements', Neuro-Oncology Advances, 3, pp. vdab087-, http://dx.doi.org/10.1093/noajnl/vdab087
,2021, 'The important role of routine cytopathology in pediatric precision oncology', Cancer Cytopathology, 129, pp. 805 - 818, http://dx.doi.org/10.1002/cncy.22448
,2020, 'Recurrent SPECC1L–NTRK fusions in pediatric sarcoma and brain tumors', Cold Spring Harbor Molecular Case Studies, 6, pp. mcs.a005710, http://dx.doi.org/10.1101/MCS.A005710
,2020, 'Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer', Nature Medicine, 26, pp. 1742 - 1753, http://dx.doi.org/10.1038/s41591-020-1072-4
,2020, 'ABCC4/MRP4 contributes to the aggressiveness of Myc-associated epithelial ovarian cancer', International Journal of Cancer, 147, pp. 2225 - 2238, http://dx.doi.org/10.1002/ijc.33005
,2020, 'CD30 and ALK combination therapy has high therapeutic potency in RANBP2-ALK-rearranged epithelioid inflammatory myofibroblastic sarcoma', British Journal of Cancer, 123, pp. 1101 - 1113, http://dx.doi.org/10.1038/s41416-020-0996-2
,2020, 'Suppression of ABCE1-mediated mRNA translation limits N-MYC-driven cancer progression', Cancer Research, 80, pp. 3706 - 3718, http://dx.doi.org/10.1158/0008-5472.CAN-19-3914
,2020, 'Fatty acid synthase and adenosine monophosphate-activated protein kinase regulate cell survival and drug sensitivity in diffuse large B-cell lymphoma', Leukemia and Lymphoma, 61, pp. 1810 - 1822, http://dx.doi.org/10.1080/10428194.2020.1742899
,2020, 'Stathmin levels alter PTPN14 expression and impact neuroblastoma cell migration', British Journal of Cancer, 122, pp. 434 - 444, http://dx.doi.org/10.1038/s41416-019-0669-1
,2020, 'Accelerating development of high-risk neuroblastoma patient-derived xenograft models for preclinical testing and personalised therapy', British Journal of Cancer, 122, pp. 680 - 691, http://dx.doi.org/10.1038/s41416-019-0682-4
,2019, 'A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia', Cancer Cell, 36, pp. 660 - 673.e11, http://dx.doi.org/10.1016/j.ccell.2019.11.001
,2019, 'Drugging MYCN oncogenic signaling through the MYCN-PA2G4 binding interface', Cancer Research, 79, pp. 5652 - 5667, http://dx.doi.org/10.1158/0008-5472.CAN-19-1112
,2019, 'Rare case of cervical thymic cyst diagnosed on pre-operative imaging', ANZ Journal of Surgery, 89, pp. 1504 - 1505, http://dx.doi.org/10.1111/ans.14923
,2019, 'Complex Compound Inheritance of Lethal Lung Developmental Disorders Due to Disruption of the TBX-FGF Pathway', American Journal of Human Genetics, 104, pp. 213 - 228, http://dx.doi.org/10.1016/j.ajhg.2018.12.010
,2019, 'Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma', Science Translational Medicine, 11, http://dx.doi.org/10.1126/scitranslmed.aau1099
,2019, 'Crizotinib and surgery for long-term disease control in children and adolescents with ALK-positive inflammatory myofibroblastic tumors', JCO Precision Oncology, 3, pp. 1 - 11, http://dx.doi.org/10.1200/PO.18.00297
,2018, 'Integration of genomics, high throughput drug screening, and personalized xenograft models as a novel precision medicine paradigm for high risk pediatric cancer', Cancer Biology and Therapy, 19, pp. 1078 - 1087, http://dx.doi.org/10.1080/15384047.2018.1491498
,2018, 'Unresectable VIP-secreting neuroblastoma: Efficacy of debulking and steroids for symptom control', Pediatric Blood and Cancer, 65, http://dx.doi.org/10.1002/pbc.27358
,2018, 'Clinical Importance of Myc Family Oncogene Aberrations in Epithelial Ovarian Cancer', JNCI: Cancer Spectrum, 2, pp. pky047, http://dx.doi.org/10.1093/jncics/pky047
,2018, 'Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma', British Journal of Cancer, 119, pp. 693 - 696, http://dx.doi.org/10.1038/s41416-018-0251-2
,2018, 'Rare MYC-amplified Neuroblastoma With Large Cell Histology', Pediatric and Developmental Pathology, 21, pp. 461 - 466, http://dx.doi.org/10.1177/1093526617749670
,2018, 'Targeted doxorubicin-loaded bacterially derived nano-cells for the treatment of neuroblastoma', Molecular Cancer Therapeutics, 17, pp. 1012 - 1023, http://dx.doi.org/10.1158/1535-7163.MCT-17-0738
,2018, 'Analysis of eosinophilic esophagitis in children with repaired congenital esophageal atresia', Journal of Allergy and Clinical Immunology, http://dx.doi.org/10.1016/j.jaci.2018.08.040
,2017, 'Suppression of the ATP-binding cassette transporter ABCC4 impairs neuroblastoma tumour growth and sensitises to irinotecan in vivo', European Journal of Cancer, 83, pp. 132 - 141, http://dx.doi.org/10.1016/j.ejca.2017.06.024
,2017, 'Pre-clinical study of panobinostat in xenograft and genetically engineered murine diffuse intrinsic pontine glioma models', PLoS ONE, 12, pp. e0169485, http://dx.doi.org/10.1371/journal.pone.0169485
,2017, 'Antenatal gastrointestinal anomalies in neonates subsequently found to have alveolar capillary dysplasia', Clinical Case Reports, 5, pp. 559 - 566, http://dx.doi.org/10.1002/ccr3.888
,2016, 'Resolution of intestinal histopathology changes in cystic fibrosis after treatment with ivacaftor', Annals of the American Thoracic Society, 13, pp. 297 - 298, http://www.atsjournals.org/doi/abs/10.1513/AnnalsATS.201510-669LE?journalCode=annalsats
,2015, 'Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma', Science Translational Medicine, 7, pp. 312ra176, http://dx.doi.org/10.1126/scitranslmed.aab1803
,2015, 'Barrett's esophagus and eosinophilic esophagitis in a young pediatric patient with esophageal atresia', Journal of Pediatric Surgery Case Reports, 3, pp. 272 - 275, http://dx.doi.org/10.1016/j.epsc.2015.05.004
,2013, 'B-blockers increase response to chemotherapy via direct antitumour and anti-angiogenic mechanisms in neuroblastoma', British Journal of Cancer, 108, pp. 2485 - 2494, http://dx.doi.org/10.1038/bjc.2013.205
,2012, 'Remote frozen section examination of breast sentinel lymph nodes by telepathology', ANZ Journal of Surgery, 82, pp. 803 - 808, http://dx.doi.org/10.1111/j.1445-2197.2012.06191.x
,2009, 'Accessory spleen masquerading as a pancreatic neoplasm', American Journal of Surgery, 197, http://dx.doi.org/10.1016/j.amjsurg.2008.07.063
,2009, 'Reduced folate carrier and methylenetetrahydrofolate reductase gene polymorphisms: associations with clinical outcome in childhood acute lymphoblastic leukemia', Leukemia, 23, pp. 1348 - 1351, http://dx.doi.org/10.1038/leu.2009.67
,2007, 'Intrapancreatic splenunculus', American Journal of Surgery, 194, pp. 75 - 76, http://dx.doi.org/10.1016/j.amjsurg.2006.11.022
,2002, 'Role of E45K reduced folate carrier gene mutation in methotrexate resistance in human leukaemia cells', Leukemia, 16, pp. 2379 - 2387
,2001, 'Single nucleotide polymorphisms in the human reduced folate carrier: characterization of a high-frequency G.A variant at position 80 and transport properties of the his27 And Arg27 carriers', Clinical Cancer Research, 7, pp. 3416 - 3422, https://aacrjournals.org/clincancerres/article/7/11/3416/288667/Single-Nucleotide-Polymorphisms-in-the-Human
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