By Dr Chamini Jayamali Perera

Book Chapters

Pang T; Xu Z; Perera C; Apte MV, 2023, 'Tumor Microenvironment', in , Wiley, pp. 942 - 950, http://dx.doi.org/10.1002/9781119876007.ch123

Pang T; Xu Z; Perera C; Apte MV, 2023, 'Tumor Microenvironment: Immune Cells and Immunosuppressive Functions of Carcinoma-associated Fibroblasts and Macrophages', in The Pancreas: an Integrated Textbook of Basic Science, Medicine, and Surgery, Fourth Edition, Wiley, pp. 942 - 950, http://dx.doi.org/10.1002/9781119876007.ch123

Lees JG; Fivelman B; Duffy SS; Makker PGS; Perera CJ; Moalem-Taylor G, 2015, 'Cytokines in neuropathic pain and associated depression', in , pp. 51 - 66, http://dx.doi.org/10.1159/000435932

Journal articles

Perera CJ; Hosen SZ; Khan T; Fang H; Mekapogu AR; Xu Z; Falasca M; Chari ST; Wilson JS; Pirola R; Greening DW; Apte MV, 2024, 'Proteomic profiling of small extracellular vesicles derived from mouse pancreatic cancer and stellate cells: Role in pancreatic cancer', Proteomics, 24, http://dx.doi.org/10.1002/pmic.202300067

Sarkar R; Xu Z; Perera CJ; Apte MV, 2023, 'Emerging role of pancreatic stellate cell-derived extracellular vesicles in pancreatic cancer', Seminars in Cancer Biology, 93, pp. 114 - 122, http://dx.doi.org/10.1016/j.semcancer.2023.05.007

Mekapogu AR; Xu Z; Pothula S; Perera C; Pang T; Hosen SMZ; Damalanka V; Janetka J; Goldstein D; Pirola R; Wilson J; Apte M, 2023, 'HGF/c-Met pathway inhibition combined with chemotherapy increases cytotoxic T-cell infiltration and inhibits pancreatic tumour growth and metastasis', Cancer Letters, 568, http://dx.doi.org/10.1016/j.canlet.2023.216286

Binang HB; Perera CJ; Apte MV, 2023, 'Role of Pancreatic Tumour-Derived Exosomes and Their Cargo in Pancreatic Cancer-Related Diabetes', International Journal of Molecular Sciences, 24, pp. 10203, http://dx.doi.org/10.3390/ijms241210203

Hosen SMZ; Uddin MN; Xu Z; Buckley BJ; Perera C; Pang TCY; Mekapogu AR; Moni MA; Notta F; Gallinger S; Pirola R; Wilson J; Ranson M; Goldstein D; Apte M, 2022, 'Metastatic phenotype and immunosuppressive tumour microenvironment in pancreatic ductal adenocarcinoma: Key role of the urokinase plasminogen activator (PLAU)', Frontiers in Immunology, 13, http://dx.doi.org/10.3389/fimmu.2022.1060957

Cederholm JME; Parley KE; Perera CJ; von Jonquieres G; Pinyon JL; Julien JP; Ryugo DK; Ryan AF; Housley GD, 2022, 'Noise-induced hearing loss vulnerability in type III intermediate filament peripherin gene knockout mice', Frontiers in Neurology, 13, http://dx.doi.org/10.3389/fneur.2022.962227

Channon LM; Tyma VM; Xu Z; Greening DW; Wilson JS; Perera CJ; Apte MV, 2022, 'Small extracellular vesicles (exosomes) and their cargo in pancreatic cancer: Key roles in the hallmarks of cancer', Biochimica et Biophysica Acta - Reviews on Cancer, 1877, pp. 188728, http://dx.doi.org/10.1016/j.bbcan.2022.188728

Perera CJ; Falasca M; Chari ST; Greenfield JR; Xu Z; Pirola RC; Wilson JS; Apte MV, 2021, 'Role of pancreatic stellate cell-derived exosomes in pancreatic cancer-related diabetes: A novel hypothesis', Cancers, 13, pp. 5224, http://dx.doi.org/10.3390/cancers13205224

Xu Z; Pang TCY; Liu AC; Pothula SP; Mekapogu AR; Perera CJ; Murakami T; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2020, 'Targeting the HGF/c-MET pathway in advanced pancreatic cancer: a key element of treatment that limits primary tumour growth and eliminates metastasis', British Journal of Cancer, 122, pp. 1486 - 1495, http://dx.doi.org/10.1038/s41416-020-0782-1

Housley DM; Pinyon JL; Von Jonquieres G; Perera CJ; Smout M; Liddell MJ; Jennings EA; Wilson D; Housley GD, 2020, 'Australian scorpion Hormurus waigiensis venom fractions show broad bioactivity through modulation of bio-impedance and cytosolic calcium', Biomolecules, 10, http://dx.doi.org/10.3390/biom10040617

Perera C; Xu Z; Mekapogu AR; Hosen SMZ; Pothula S; Greenfield J; Chari S; Goldstein D; Pirola R; Wilson J; Apte MV, 2020, '1133 PANCREATIC STELLATE CELL AND CANCER CELL DERIVED EXOSOMES IMPAIR BETA CELL FUNCTION: IMPLICATIONS FOR PANCREATIC CANCER RELATED DIABETES.', Gastroenterology, 158, pp. S - 221, http://dx.doi.org/10.1016/s0016-5085(20)31245-2

Duffy SS; Keating BA; Perera CJ; Lees JG; Tonkin RS; Makker PGS; Carrive P; Butovsky O; Moalem-Taylor G, 2019, 'Regulatory T cells and their derived cytokine, interleukin-35, reduce pain in experimental autoimmune encephalomyelitis', Journal of Neuroscience, 39, pp. 2326 - 2346, http://dx.doi.org/10.1523/JNEUROSCI.1815-18.2019

Duffy SS; Keating BA; Perera CJ; Moalem-Taylor G, 2018, 'The role of regulatory T cells in nervous system pathologies', Journal of Neuroscience Research, 96, pp. 951 - 968, http://dx.doi.org/10.1002/jnr.24073

Duffy SS; Lees JG; Perera CJ; Moalem-Taylor G, 2018, 'Managing neuropathic pain in multiple sclerosis: Pharmacological interventions', Medicinal Chemistry, 14, pp. 106 - 119, http://dx.doi.org/10.2174/1573406413666170906122508

Tonkin RS; Bowles C; Perera CJ; Keating BA; Makker PGS; Duffy SS; Lees JG; Tran C; Don AS; Fath T; Liu L; O'Carroll SJ; Nicholson LFB; Green CR; Gorrie C; Moalem-Taylor G, 2018, 'Attenuation of mechanical pain hypersensitivity by treatment with Peptide5, a connexin-43 mimetic peptide, involves inhibition of NLRP3 inflammasome in nerve-injured mice', Experimental Neurology, 300, pp. 1 - 12, http://dx.doi.org/10.1016/j.expneurol.2017.10.016

Makker PGS; Duffy SS; Lees JG; Perera CJ; Tonkin RS; Butovsky O; Park SB; Goldstein D; Moalem-Taylor G, 2017, 'Characterisation of immune and neuroinflammatory changes associated with chemotherapy-induced peripheral neuropathy', PLoS ONE, 12, pp. e0170814, http://dx.doi.org/10.1371/journal.pone.0170814

Duffy SS; Perera CJ; Makker PGS; Lees JG; Carrive P; Moalem-Taylor G, 2016, 'Peripheral and central neuroinflammatory changes and pain behaviors in an animal model of multiple sclerosis', Frontiers in Immunology, 7, pp. 369, http://dx.doi.org/10.3389/fimmu.2016.00369

Perera CJ; Lees JG; Duffy SS; Makker PGS; Fivelman B; Apostolopoulos V; Moalem-Taylor G; Perera C, 2015, 'Effects of active immunisation with myelin basic protein and myelin-derived altered peptide ligand on pain hypersensitivity and neuroinflammation', Journal of Neuroimmunology, 286, pp. 59 - 70, http://dx.doi.org/10.1016/j.jneuroim.2015.07.004

Perera CJ; Duffy SS; Lees JG; Kim CF; Cameron B; Apostolopoulos V; Moalem-Taylor G, 2015, 'Active immunization with myelin-derived altered peptide ligand reduces mechanical pain hypersensitivity following peripheral nerve injury', Journal of Neuroinflammation, 12, http://dx.doi.org/10.1186/s12974-015-0253-4

Lees JG; Duffy SS; Perera CJ; Moalem-Taylor G; Perera C, 2015, 'Depletion of Foxp3+ regulatory T cells increases severity of mechanical allodynia and significantly alters systemic cytokine levels following peripheral nerve injury', Cytokine, 71, pp. 207 - 214, http://dx.doi.org/10.1016/j.cyto.2014.10.028

Tian DH; Perera CJ; Moalem-Taylor G, 2013, 'Neuropathic pain in animal models of nervous system autoimmune diseases', Mediators of Inflammation, 2013, http://dx.doi.org/10.1155/2013/298326

Tian DH; Perera CJ; Apostolopoulos V; Moalem-Taylor G, 2013, 'Effects of vaccination with altered peptide ligand on chronic pain in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis', Frontiers in Neurology, http://dx.doi.org/10.3389/fneur.2013.00168

Austin P; Kim CF; Perera C; Moalem-Taylor G, 2012, 'Regulatory T cells attenuate neuropathic pain following peripheral nerve injury and experimental autoimmune neuritis', Pain, 153, pp. 1916 - 1931, http://dx.doi.org/10.1016/j.pain.2012.06.005

Conference Papers

Perera C; Hossain MJ; Mekapogu AR; Hosen SMZ; Rajan P; Xu Z; Greenfield J; Hoehn K; Horadagoda N; Chari S; Pirola R; Wilson J; Apte MV, 2022, 'Su1261: PANCREATIC CANCER-RELATED DIABETES: A HIGH FRUCTOSE DIET FED TO TRANSGENIC, KRASLSL-G12D/+; PDXCRE/+ (KC) MICE, IS ASSOCIATED WITH PANCREATIC STELLATE CELL ACTIVATION AND ACCELERATED CANCER PROGRESSION', in Gastroenterology, Elsevier BV, http://dx.doi.org/10.1016/s0016-5085(22)61328-3

Mekapogu A; Xu Z; Pothula S; Perera C; Pang T; Hosen SMS; Damalanka V; Mahoney V; Janekta J; Klampfer L; Goldstein D; Pirola R; Wilson J; Apte M; Perera C, 2021, 'Hepatocyte growth factor/c-MET inhibition plus chemotherapy improves tumor immunity and eliminates metastasis in pancreatic cancer', Virtual, presented at Australian Gastroenterology Week, Virtual, 10 August 2021

Mekapogu AR; Xu Z; Pothula S; Perera C; Pang T; Hosen SMZ; Damalanka VC; Mahoney M; Janetka JW; Klampfer L; Goldstein D; Pirola R; Wilson J; Apte MV, 2021, '184 HEPATOCYTE GROWTH FACTOR/ C-MET PATHWAY INHIBITION COMBINED WITH CHEMOTHERAPY RETARDS PRECURSOR PANINS AND POTENTIATES LOCAL IMMUNITY IN A TRANSGENIC MODEL OF EARLY PANCREATIC CANCER', in Gastroenterology, Elsevier BV, pp. S - 45, http://dx.doi.org/10.1016/s0016-5085(21)00855-6

Hosen SMZ; Haar J; Xu Z; Perera C; Buckley BJ; Mekapogu AR; Pang TC; Pothula S; Ranson M; Goldstein D; Pirola R; Wilson J; Apte M, 2021, 'Targeting the urokinase plasminogen activator (uPA) pathway inhibits pancreatic cancer progression', in Pancreatology, Elsevier BV, pp. S73 - S73, http://dx.doi.org/10.1016/j.pan.2021.05.196

Perera C; Xu Z; Mekapogu AR; Hosen SMZ; Pothula S; Greenfield J; Chari S; Goldstein D; Pirola R; Wilson J; Apte M, 2020, 'Pancreatic cancer-related diabetes: Do pancreatic stellate cell and cancer cell derived exosomes play a role?', in Pancreratology, presented at European Pancreatic Club

Perera C; Xu Z; Mekapogu AR; Hosen SMZ; Pothula S; Greenfield J; Chari S; Goldstein D; Pirola R; Wilson J; Apte M, 2020, 'I. Pancreatic Stellate Cell and Cancer Cell Derived Exosomes Impair Beta Cell Function: Implications for Pancreatic Cancer Related Diabetes', in Gastroenterology, Elsevier, Chicago, USA, presented at Digestive Disease Week, Chicago, USA, 02 May 2020, http://dx.doi.org/10.1016/S0016-5085(20)31245-2

Mekapogu A; Xu Z; Pothula S; Perera C; Pang T; Hosen Z; Janetka J; Damalanka V; Mahoney M; Klampfer L; Goldstein D; Pirola R; Wilson J; Apte M, 2020, 'Inhibition of both the ligand and receptor of the hepatocyte growth factor/c-MET pathway, in combination with chemotherapy, retards progression of PanIN lesions in KPC mice', in Pancreatology, Elsevier BV, pp. S39 - S40, http://dx.doi.org/10.1016/j.pan.2020.07.049

Xu Z; Pang T; Pothula S; Mekapogu A; Perera C; Murakami T; Goldstein D; Pirola R; Wilson J; Apte M, 2019, 'Inhibition of Hepatocyte Growth Factor (HGF) Signaling Pathway in Combination With Chemotherapy Reduces Tumour Burden in an Orthotopic Model of Advanced Pancreatic Cancer', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1551 - 1551, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000505712800617&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Xu Z; Pang T; Pothula S; Mekapogu A; Perera C; Murakami T; Goldstein D; Pirola R; Wilson J; Apte M, 2019, 'Inhibition of hepatocyte growth factor signaling pathway in combination with chemotherapy reduces tumor burden in an orthotopic model of advanced pancreatic cancer', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 37 - 38, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000483843100057&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Perera C; Von Jonquieres G; Pinyon J; Parley K; Cederholm J; Julien J-P; Ryan A; Housley G, 2016, 'Phenotyping the differential innervation of the peripherin knockout mouse cochlea', in Proceedings of the Australian Physiological Society, Adelaide, presented at Australian Physiological Society, Adelaide, 04 December 2016 - 07 December 2016

Duffy S; Lees J; Makker P; Perera C; Moalem-Taylor G, 2015, 'Central nervous system immune cell profiling in a model of chronic experimental autoimmune encephalomyelitis', in Journal of Neurochemistry, Wiley, Australia, presented at 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australa, Australia

Perera C; Duffy S; Lees J; Makker P; Tonkin R; Moalem-Taylor G, 2015, 'Effects of IL-35 gene therapy on neuroinflammation and neuropathic pain following peripheral nerve injury', in Journal of Neurochemistry, Wiley, presented at 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australa

Conference Abstracts

Sarkar R; Khan T; Binang H; Xu Z; Hosen SMZ; Mekapogu A; Hoehn K; Horada N; Pirola R; Wilson J; Perera C; Apte M, 2023, 'Pancreatic cancer related diabetes: impaired glucose tolerance and insulin signalling may drive progression of pancreatic intraepithelial neoplasms (PanINs)', in Pancreatology, Elsevier BV, Vol. 23, pp. e143 - e143, http://dx.doi.org/10.1016/j.pan.2023.06.767

Perera C; Greening D; Hosen SMZ; Mekapogu AR; Xu Z; Chari S; Falasca M; Wilson J; Pirola R; Apte M, 2023, 'Proteomic analysis of co-cultured human pancreatic stellate cells and cancer cell-derived exosome cargo: novel insights into signalling pathways in pancreatic cancer', in Pancreatology, Elsevier BV, Vol. 23, pp. e127 - e127, http://dx.doi.org/10.1016/j.pan.2023.06.729

Perera C; Hossain MJ; Mekapogu AR; Hosen SMZ; Xu Z; Greenfield J; Hoehn K; Horadagoda N; Pirola R; Wilson J; Apte M; Hosen SM, 2022, 'Impaired glucose tolerance in transgenic KC mice is associated with pancreatic stellate cell activation and accelerated pancreatic cancer progression', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, Vol. 37, pp. 32 - 32

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