By Dr Chris Jolly

Journal articles

Truong P; Shen S; Joshi S; Islam MI; Zhong L; Raftery MJ; Afrasiabi A; Alinejad-Rokny H; Nguyen M; Zou X; Bhuyan GS; Sarowar CH; Ghodousi ES; Stonehouse O; Mohamed S; Toscan CE; Connerty P; Kakadia PM; Bohlander SK; Michie KA; Larsson J; Lock RB; Walkley CR; Thoms JAI; Jolly CJ; Pimanda JE, 2024, 'TOPORS E3 ligase mediates resistance to hypomethylating agent cytotoxicity in acute myeloid leukemia cells', Nature Communications, 15, pp. 7360, http://dx.doi.org/10.1038/s41467-024-51646-6

Nimmo DG; Jolly CJ; Carthey AJR, 2023, 'Expanding the scope of fire-driven animal evolution', Trends in Ecology and Evolution, 38, pp. 1115 - 1116, http://dx.doi.org/10.1016/j.tree.2023.09.005

Moles E; Howard CB; Huda P; Karsa M; McCalmont H; Kimpton K; Duly A; Chen Y; Huang Y; Tursky ML; Ma D; Bustamante S; Pickford R; Connerty P; Omari S; Jolly CJ; Joshi S; Shen S; Pimanda JE; Dolnikov A; Cheung LC; Kotecha RS; Norris MD; Haber M; de Bock CE; Somers K; Lock RB; Thurecht KJ; Kavallaris M; Moles Meler E, 2023, 'Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia', Science translational medicine, 15, pp. eabm1262 - eabm1262, http://dx.doi.org/10.1126/scitranslmed.abm1262

Schnegg-Kaufmann AS; Thoms JAI; Bhuyan GS; Hampton HR; Vaughan L; Rutherford K; Kakadia PM; Lee HM; Johansson Beves EMV; Failes TW; Arndt GM; Koval J; Lindeman R; Warburton P; Rodriguez-Meira A; Mead AJ; Unnikrishnan A; Davidson S; Polizzotto MN; Hertzberg M; Papaemmanuil E; Bohlander SK; Faridani OR; Jolly CJ; Zanini F; Pimanda JE, 2023, 'Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy', Blood, 141, pp. 1316 - 1321, http://dx.doi.org/10.1182/blood.2022018602

Thoms JAI; Schnegg-Kaufmann A; Bhuyan GS; Hampton HR; Vaughan L; Rutherford K; Kakadia PM; Lee HM; Johansson E; Failes TW; Arndt GM; Koval J; Davidson S; Lindeman R; Warburton P; Rodriguez-Meira A; Mead AJ; Unnikrishnan A; Hertzberg M; Polizzotto MN; Papaemmanuil E; Bohlander SK; Faridani O; Jolly CJ; Zanini F; Pimanda JE, 2022, 'Clinical Response to Azacytidine (AZA) Is Associated with Increased Contribution from Mutated Blood Progenitors: Insights from Single Cell Genotyping of Matched Stem/Progenitor and Mature Blood Cells from MDS/CMML Patients Pre- and Post-AZA Treatment', Blood, 140, pp. 9751 - 9752, http://dx.doi.org/10.1182/blood-2022-163158

O’Rourke MB; Roediger BR; Jolly CJ; Crossett B; Padula MP; Hansbro PM, 2022, 'Viral Biomarker Detection and Validation Using MALDI Mass Spectrometry Imaging (MSI)', Proteomes, 10, http://dx.doi.org/10.3390/proteomes10030033

Schnegg-Kaufmann A; Thoms J; Bhuyan GS; Henry H; Vaughan L; Rutherford K; Kakadia P; Johansson E; Failes T; Greg A; Koval J; Lindeman R; Warburton P; Rodriguez-Meira A; Mead A; Unnikrishnan A; Bohlander S; Pappaemmanuil E; Faridani O; Jolly C; Zanini F; Pimanda J, 2022, 'P748: SINGLE CELL GENOTYPING OF MATCHED BONE MARROW AND PERIPHERAL BLOOD CELLS IN TREATMENT NAIVE AND AZA-TREATED MDS AND CMML', HemaSphere, 6, pp. 643 - 644, http://dx.doi.org/10.1097/01.hs9.0000845876.01682.15

Michel AO; Donovan TA; Roediger B; Lee Q; Jolly CJ; Monette S, 2022, 'Chaphamaparvovirus antigen and nucleic acids are not detected in kidney tissues from cats with chronic renal disease or immunocompromised cats', Veterinary Pathology, 59, pp. 120 - 126, http://dx.doi.org/10.1177/03009858211045439

Jolly CJ; Pimanda JE, 2020, 'Titans awake: HMAs for virus-driven ATL', Blood, 136, pp. 777 - 779, http://dx.doi.org/10.1182/blood.2020006488

Lee Q; Padula MP; Pinello N; Williams SH; O’Rourke MB; Fumagalli MJ; Orkin JD; Song R; Shaban B; Brenner O; Pimanda JE; Weninger W; de Souza WM; Melin AD; Wong JJL; Crim MJ; Monette S; Roediger B; Jolly CJ, 2020, 'Murine and related chapparvoviruses are nephro-tropic and produce novel accessory proteins in infected kidneys', PLoS Pathogens, 16, pp. e1008262, http://dx.doi.org/10.1371/journal.ppat.1008262

Gall MG; Zhang HE; Lee Q; Jolly CJ; McCaughan GW; Cook A; Roediger B; Gorrell MD, 2019, 'Immune regeneration in irradiated mice is not impaired by the absence of DPP9 enzymatic activity', Scientific Reports, 9, pp. 7292, http://dx.doi.org/10.1038/s41598-019-43739-w

Poyntz HC; Jones A; Jauregui R; Young W; Gestin A; Mooney A; Lamiable O; Altermann E; Schmidt A; Gasser O; Weyrich L; Jolly CJ; Linterman MA; Gros GL; Hawkins ED; Forbes-Blom E, 2019, 'Genetic regulation of antibody responsiveness to immunization in substrains of BALB/c mice', Immunology and Cell Biology, 97, pp. 39 - 53, http://dx.doi.org/10.1111/imcb.12199

Jolly C; Lee Q; Padula M; Pinello N; Williams S; O’Rourke M; Fumagalli MJ; Orkin J; Shaban B; Brenner O; Weninger W; de Souza WM; Melin A; Wong JJ-L; Crim M; Monette S; Roediger B, 2019, 'MKPV (aka MuCPV) and related chapparvoviruses are nephro-tropic and encode novel accessory proteins p15 and NS2', , http://dx.doi.org/10.1101/732537

Roediger B; Lee Q; Tikoo S; Cobbin JCA; Henderson JM; Jormakka M; O'Rourke MB; Padula MP; Pinello N; Henry M; Wynne M; Santagostino SF; Brayton CF; Rasmussen L; Lisowski L; Tay SS; Harris DC; Bertram JF; Dowling JP; Bertolino P; Lai JH; Wu W; Bachovchin WW; Wong JJL; Gorrell MD; Shaban B; Holmes EC; Jolly CJ; Monette S; Weninger W, 2018, 'An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis', Cell, 175, pp. 530 - 543.e24, http://dx.doi.org/10.1016/j.cell.2018.08.013

Jolly C; Gall M; Gorrell M; Cook A; Roediger B; Zhang HE; McCaughan G, 2018, 'Immune regeneration in irradiated mice is not impaired by the absence of DPP9 enzymatic activity [forthcoming publication]', Forthcoming/preprint available in bioRxiv, http://dx.doi.org/10.1101/431775

Thientosapol ES; Bosnjak D; Durack T; Stevanovski I; Van Geldermalsen M; Holst J; Jahan Z; Shepard C; Weninger W; Kim B; Brink R; Jolly CJ, 2018, 'SAMHD1 enhances immunoglobulin hypermutation by promoting transversion mutation', Proceedings of the National Academy of Sciences of the United States of America, 115, pp. 4921 - 4926, http://dx.doi.org/10.1073/pnas.1719771115

Wang XM; Holz LE; Chowdhury S; Cordoba SP; Evans KA; Gall MG; De Ribeiro AJV; Zheng YZ; Levy MT; Yu DMT; Yao TW; Polak N; Jolly CJ; Bertolino P; McCaughan GW; Gorrell MD, 2017, 'The pro-fibrotic role of dipeptidyl peptidase 4 in carbon tetrachloride-induced experimental liver injury', Immunology and Cell Biology, 95, pp. 443 - 453, http://dx.doi.org/10.1038/icb.2016.116

Thientosapol ES; Sharbeen G; Edwin Lau KK; Bosnjak D; Durack T; Stevanovski I; Weninger W; Jolly CJ, 2017, 'Proximity to AGCT sequences dictates MMR-independent versus MMR-dependent mechanisms for AID-induced mutation via UNG2', Nucleic Acids Research, 45, pp. 3146 - 3157, http://dx.doi.org/10.1093/nar/gkw1300

Chang GH; Lay AJ; Ting KK; Zhao Y; Coleman PR; Powter EE; Formaz-Preston A; Jolly CJ; Bower NI; Hogan BM; Rinkwitz S; Becker TS; Vadas MA; Gamble JR, 2014, 'Arhgap18: An endogenous inhibitor of angiogenesis, limiting tip formation and stabilizing junctions', Small GTPases, 5, http://dx.doi.org/10.4161/21541248.2014.975002

Sharbeen G; Yee CWY; Smith AL; Jolly CJ, 2012, 'Ectopic restriction of DNA repair reveals that UNG2 excises AID-induced uracils predominantly or exclusively during G1 phase', Journal of Experimental Medicine, 209, pp. 965 - 974, http://dx.doi.org/10.1084/jem.20112379

Chan TD; Wood K; Hermes JR; Jolly CJ; Basten A; Brink R, 2012, 'Elimination of germinal-center-derived self-reactive B cells is governed by the location and concentration of self-antigen', Immunity, 37, pp. 893 - 904, http://dx.doi.org/10.1016/j.immuni.2012.07.017

Sharbeen G; Cook AJL; Lau KKE; Raftery J; Yee CWY; Jolly CJ, 2010, 'Incorporation of dUTP does not mediate mutation of A:T base pairs in Ig genes in vivo', Nucleic Acids Research, 38, pp. 8120 - 8130, http://dx.doi.org/10.1093/nar/gkq682

Jolly CJ; Cook AJL; Manis JP, 2008, 'Fixing DNA breaks during class switch recombination', Journal of Experimental Medicine, 205, pp. 509 - 513, http://dx.doi.org/10.1084/jem.20080356

Jolly C; Cook AJL; Raftery J; Jones ME, 2007, 'Corrigendum to "Measuring bidirectional mutation". [J. Theor. Biol. 246 (2006) 269-277] (DOI:10.1016/j.jtbi.2006.12.034)', Journal of Theoretical Biology, 247, pp. 862, http://dx.doi.org/10.1016/j.jtbi.2007.05.027

Jolly C; Cook AJL; Raferty J; Jones ME, 2007, 'Measuring bidirectional mutation', Journal of Theoretical Biology, 246, pp. 269 - 277, http://dx.doi.org/10.1016/j.jtbi.2006.12.034

Cook AJL; Raftery JM; Lau KKE; Jessup A; Harris RS; Takeda S; Jolly CJ, 2007, 'DNA-dependent protein kinase inhibits AID-induced antibody gene conversion', PLoS Biology, 5, pp. 792 - 799, http://dx.doi.org/10.1371/journal.pbio.0050080

Cook AJL; Oganesian L; Harumal P; Basten A; Brink R; Jolly CJ, 2003, 'Reduced Switching in SCID B Cells Is Associated with Altered Somatic Mutation of Recombined S Regions', Journal of Immunology, 171, pp. 6556 - 6564, http://dx.doi.org/10.4049/jimmunol.171.12.6556

Jolly CJ; Neuberger MS, 2001, 'Somatic hypermutation of immunoglobulin κ transgenes: Association of mutability with demethylation', Immunology and Cell Biology, 79, pp. 18 - 22, http://dx.doi.org/10.1046/j.1440-1711.2001.00968.x

Neuberger MS; Sale JE; Cumbers SJ; Jolly CJ; Bemark MP; Ehrenstein MR; Lanoue A; Brüggemann M; Batista FD; Davies SL; Williams GT, 2000, 'Diversification and selection mechanisms for the production of protein repertoires: Lessons from the immune system', Applied Biochemistry and Biotechnology - Part A Enzyme Engineering and Biotechnology, 83, pp. 53 - 62, http://dx.doi.org/10.1385/ABAB:83:1-3:53

Williams GT; Jolly CJ; Köhler J; Neuberger MS, 2000, 'The contribution of somatic hypermutation to the diversity of serum immunoglobulin: Dramatic increase with age', Immunity, 13, pp. 409 - 417, http://dx.doi.org/10.1016/S1074-7613(00)00040-6

Neuberger MS; Ehrenstein MR; Klix N; Jolly CJ; Yélamos J; Rada C; Milstein C, 1998, 'Monitoring and interpreting the intrinsic features of somatic hypermutation', Immunological Reviews, 162, pp. 107 - 116, http://dx.doi.org/10.1111/j.1600-065X.1998.tb01434.x

Klix N; Jolly CJ; Davies SL; Brüggemann M; Williams GT; Neuberger MS, 1998, 'Multiple sequences from downstream of the J(κ) cluster can combine to recruit somatic hypermutation to a heterologous, upstream mutation domain', European Journal of Immunology, 28, pp. 317 - 326, http://dx.doi.org/10.1002/(SICI)1521-4141(199801)28:01<317::AID-IMMU317>3.0.CO;2-S

Jolly CJ; Klix N; Neuberger MS, 1997, 'Rapid methods for the analysis of immunoglobulin gene hypermutation: Application to transgenic and gene targeted mice', Nucleic Acids Research, 25, pp. 1913 - 1919, http://dx.doi.org/10.1093/nar/25.10.1913

Jolly CJ; O'Neill HC, 1997, 'Specific transcription of the unrearranged TCR Vβ8.2 gene in lymphoid tissues occurs independently of V(D)J rearrangement', Immunology and Cell Biology, 75, pp. 13 - 20, http://dx.doi.org/10.1038/icb.1997.3

Jolly CJ; Glenn GM; Rahman S, 1996, 'GSP-1 genes are linked to the grain hardness locus (Ha) on wheat chromosome 5D', Proceedings of the National Academy of Sciences of the United States of America, 93, pp. 2408 - 2413, http://dx.doi.org/10.1073/pnas.93.6.2408

Jolly CJ; Wagner SD; Rada C; Klix N; Milstein C; Neuberger MS, 1996, 'The targeting of somatic hypermutation', Seminars in Immunology, 8, pp. 159 - 168, http://dx.doi.org/10.1006/smim.1996.0020

Jolly CJ; O'neill HC, 1995, 'Expression of a TCR Vβ8.2 polypeptide from the unrearranged gene in a murine lymphoid precursor cell line', International Immunology, 7, pp. 1147 - 1156, http://dx.doi.org/10.1093/intimm/7.7.1147

O'Neill HC; Jolly CJ, 1995, 'Germline transcription and expression of Tcrb-V8 genes in peripheral mouse lymphoid tissues', Immunogenetics, 42, pp. 309 - 314, http://dx.doi.org/10.1007/BF00179391

Ho ESP; Jolly CJ; O'Neill HC, 1994, 'Analysis of oncogenic progression in a radiation leukemia virus model', Leukemia, 8, pp. 1202 - 1213

RAHMAN S; JOLLY CJ; SKERRITT JH; WALLOSHECK A, 1994, 'Cloning of a wheat 15‐kDa grain softness protein (GSP): GSP is a mixture of puroindoline‐like polypeptides', European Journal of Biochemistry, 223, pp. 917 - 925, http://dx.doi.org/10.1111/j.1432-1033.1994.tb19069.x

Jolly CJ; Rahman S; Kortt AA; Higgins TJV, 1993, 'Characterisation of the wheat Mr 15000 "grain-softness protein" and analysis of the relationship between its accumulation in the whole seed and grain softness', Theoretical and Applied Genetics, 86, pp. 589 - 597, http://dx.doi.org/10.1007/BF00838714

O'Neill HC; Jolly C, 1992, 'Retroviral superantigens', Immunology Today, 13, pp. 462 - 463, http://dx.doi.org/10.1016/0167-5699(92)90078-L

Jolly CJ; Reid JB; Ross JJ, 1987, 'Internode length in Pisum. Action of gene lw', Physiologia Plantarum, 69, pp. 489 - 498, http://dx.doi.org/10.1111/j.1399-3054.1987.tb09230.x

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