Select Publications

Journal articles

Squires JE; Patel HR; Nousch M; Sibbritt T; Humphreys DT; Parker BJ; Suter CM; Preiss T, 2012, 'Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA', Nucleic Acids Research, 40, pp. 5023 - 5033, http://dx.doi.org/10.1093/nar/gks144

Preiss T; Clancy JL; Wei G; Echner N; Humphreys D; Beilharz TH, 2011, 'mRNA isoform diversity can obscure detection of miRNA-mediated control of translation', RNA - a Publication of the RNA Society, 17, pp. 1025 - 1031

Schonrock N; Humphreys D; Preiss T; Gotz J, 2011, 'Target Gene Repression Mediated by miRNAs miR-181c and miR-9 Both of Which Are Down-regulated by Amyloid-beta', Journal of Molecular Neuroscience, 46, pp. 324 - 335, http://dx.doi.org/10.1007/s12031-011-9587-2

Larance M; Rowland AF; Hoehn KL; Humphreys D; Preiss T; Guilhaus M; James DE, 2010, 'Global phosphoproteomics identifies a major role for AKT and 14-3-3 in regulating EDC3', Molecular and Cellular Proteomics, 9, pp. 682 - 694, http://dx.doi.org/10.1074/mcp.M900435-MCP200

Schonrock N; Yazi DK; Humphreys D; Staufenbiel M; Ittner LM; Preiss T; Gotz J, 2010, 'Neuronal microRNA deregulation in response to Alzheimer's disease amyloid-beta', PLoS One, 5, pp. e11070, http://dx.doi.org/10.1371/journal.pone.0011070

Beilharz TH; Humphreys D; Clancy JL; Thermann R; Martin DI; Hentze MW; Preiss T, 2009, 'MicroRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells', PLoS One, 4

Clancy JL; Nousch M; Humphreys D; Westman B; Beilharz TH; Preiss T, 2007, 'Methods to analyze microRNA-mediated control of mRNA translation', Methods in Enzymology, 431, pp. 83 - 112

Lu DP; Read RL; Humphreys DT; Battah FM; Martin DIK; Rasko JEJ, 2005, 'PCR-based expression analysis and identification of microRNAs.', J RNAi Gene Silencing, 1, pp. 44 - 49, https://www.ncbi.nlm.nih.gov/pubmed/19771204

Humphreys D; Westman B; Martin DI; Preiss T, 2005, 'MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function', Proceedings of the National Academy of Sciences of the United States of America, 102, pp. 16961 - 16966

Hochgrebe TT; Humphreys D; Wilson MR; Easterbrook-Smith SB, 1999, 'A reexamination of the role of clusterin as a complement regulator', Experimental Cell Research, 249, pp. 13 - 21, http://dx.doi.org/10.1006/excr.1999.4459

Humphreys DT; Carver JA; Easterbrook-Smith SB; Wilson MR, 1999, 'Clusterin has chaperone-like activity similar to that of small heat shock proteins', Journal of Biological Chemistry, 274, pp. 6875 - 6881, http://dx.doi.org/10.1074/jbc.274.11.6875

Humphreys DT; Wilson MR, 1999, 'Modes of L929 cell death induced by TNF-α and other cytotoxic agents', Cytokine, 11, pp. 773 - 782, http://dx.doi.org/10.1006/cyto.1998.0492

Humphreys D; Hochgrebe TT; Easterbrook-Smith SB; Tenniswood MP; Wilson MR, 1997, 'Effects of clusterin overexpression on TNFα- and TGFβ-mediated death of L929 cells', Biochemistry, 36, pp. 15233 - 15243, http://dx.doi.org/10.1021/bi9703507

Conference Papers

Nicks AM; Holman SR; Chan AY; Pang C-HJ; Tsang M; Naqvi N; Husain A; Li M; Humphreys DT; Smith NJ; Iismaa SE; Graham RM, 2021, 'A Standardized Method to Isolate and Purify Cardiomyocytes from Individual Mouse Hearts Irrespective of Postnatal Age', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000752020004371&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Tarr I; Hesselson S; Iismaa S; Troup M; Young P; Mishra K; Wong C; Junday K; Humphreys D; Dunwoodie S; Fatkin D; Muller D; Graham RM; Giannoulatou E, 2021, 'Disease-Specific and Comorbidity-Related Polygenic Risk in Spontaneous Coronary Artery Dissection', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000752020004372&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Nicks AM; Humphreys DT; Holman SR; Chan AY; Djordjevic D; Naqvi N; Husain A; Smith NJ; Ho JW; Iismaa SE; Graham RM, 2018, 'Transcription Factors Driving Postnatal Cardiomyocyte Maturation', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000528619405230&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Coleman JL; Mouat MA; Wu J; Jancovski N; Humphreys DT; Stefani M; Dos Remedios CG; Feneley MP; Allen AM; Graham RM; Smith NJ, 2017, 'Blood Pressure is Increased in Female Mice Lacking Orphan G Protein-Coupled Receptor Gpr37L1', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, VA, Pentagon City, presented at Quality of Care and Outcomes Research Scientific Sessions, VA, Pentagon City, 02 April 2017 - 03 April 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000396815605115&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Nicks AM; Holman SR; Chan A; Humphreys DT; Smith NJ; Ho JW; Naqvi N; Husain A; Graham RM; Iismaa SE, 2016, 'Distinct Transcriptomic Signatures Across Postnatal Cardiomyocyte Development', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, LA, New Orleans, presented at Scientific Sessions of the American-Heart-Association / Resuscitation Science Symposium, LA, New Orleans, 12 November 2016 - 16 November 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000396816606015&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Deakin CT; Deakin JJ; Ginn SL; Young P; Humphreys D; Suter CM; Alexander IE; Hallwirth CV, 2014, 'Impact of next-generation sequencing error on analysis of barcoded plasmid libraries of known complexity and sequence', in Nucleic Acids Research, http://dx.doi.org/10.1093/nar/gku607

Conference Abstracts

Tarr I; Hesselson S; Iismaa S; Troup M; Young P; Mishra K; Wong C; Junday K; Humphreys D; Dunwoodie S; Fatkin D; Muller D; Graham RM; Giannoulatou E, 2021, 'Abstract 11949: Disease-Specific and Comorbidity-Related Polygenic Risk in Spontaneous Coronary Artery Dissection', in Circulation, Vol. 144, pp. a11949 - a11949, http://dx.doi.org/10.1161/circ.144.suppl_1.11949

Olesen M; Liang B; Soka M; Larsen AP; Knop FK; Wang F; Nielsen JB; Andersen MN; Humphreys D; Mann SA; Vandenberg JI; Svendsen JH; Haunso S; Preiss T; Seebohm G; Olesen S-P; Schmitt N; Fatkin D, 2013, 'TASK-1 potassium channel mutations in atrial fibrillation', in EUROPEAN HEART JOURNAL, OXFORD UNIV PRESS, NETHERLANDS, Amsterdam, Vol. 34, pp. 642 - 642, presented at Congress of the European-Society-of-Cardiology (ESC), NETHERLANDS, Amsterdam, 31 August 2013 - 04 September 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000327744604084&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Working Papers

Patrick R; Humphreys D; Janbandhu V; Oshlack A; Ho JWK; Ho JWK; Harvey R; Lo K, 2019, Sierra: discovery of differential transcript usage from polyA-captured single-cell RNA-seq data, http://dx.doi.org10.1101/867309

Preprints

Cornejo-Páramo P; Zhang X; Louis L; Yang Y-H; Li Z; Humphreys D; Wong E, 2024, A Bag-Of-Motif Model Captures Cell States at Distal Regulatory Sequences, , http://dx.doi.org/10.1101/2024.01.03.574012

Humphreys DT; Lewis A; Pan-Castillo B; Berti G; Mein C; Wozniak E; Gordon H; Gadhok R; Minicozzi A; ChinAleong J; Feakins R; Giannoulatou E; James LK; Stagg AJ; Lindsay JO; Silver A, 2023, Single cell sequencing data identify distinct B cell and fibroblast populations in stricturing Crohn’s disease, , http://dx.doi.org/10.1101/2023.09.04.556163

Murtha LA; Hardy SA; Mabotuwana NS; Bigland MJ; Bailey T; Raguram K; Liu S; Ngo DT; Sverdlov AL; Tomin T; Birner-Gruenberger R; Hume RD; Iismaa SE; Humphreys DT; Patrick R; Chong JJH; Lee RJ; Harvey RP; Graham RM; Rainer PP; Boyle AJ, 2023, Fibulin-3 is necessary to prevent cardiac rupture following myocardial infarction, , http://dx.doi.org/10.21203/rs.3.rs-3055737/v1

Marjaneh MM; Kirk E; Patrick R; Alankerage D; Humphreys D; Del Monte-Nieto G; Cornejo-Paramo P; Janbandhu V; Doan T; Dunwoodie S; Wong E; Moran C; Martin ICA; Thomson P; Harvey R, 2022, Quantitative trait and transcriptome analysis of genetic complexity underpinning cardiac interatrial septation in mice using an advanced intercross line, , http://dx.doi.org/10.1101/2022.10.31.514499

Nicks A; Holman S; Chan A; Tsang M; Young P; Humphreys D; Naqvi N; Husain A; Li M; Smith N; Iismaa S; Graham R, 2021, Standardised method for cardiomyocyte isolation and purification from individual murine neonatal, infant, and adult hearts, , http://dx.doi.org/10.1101/2021.09.30.462562


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